Erika Cretney

Characterization of Blimp-1 function in effector regulatory T cells

Erika Cretney, Patrick SK Leung, Stephanie Trezise, Dane M Newman, Lucille C Rankin, Charis E Teh, Tracy L Putoczki, Daniel HD Gray, Gabrielle T Belz, Lisa A Mielke, Sheila Dias, Stephen L Nutt

Journal article  |  2018  |  JOURNAL OF AUTOIMMUNITY

Regulatory T (Treg) cells maintain immunological tolerance in steady-state and after immune challenge. Activated Treg cells can un..

Association of Regulatory T-Cell Expansion With Progression of Amyotrophic Lateral Sclerosis A Study of Humans and a Transgenic Mouse Model

Rebecca K Sheean, Fiona C McKay, Erika Cretney, Christopher R Bye, Nirma D Perera, Doris Tomas, Richard A Weston, Karlene J Scheller, Elvan Djouma, Parvathi Menon, Stephen D Schibeci, Najwa Marmash, Justin J Yerbury, Stephen L Nutt, David R Booth, Graeme J Stewart, Mathew C Kiernan, Steve Vucic, Bradley J Turner

Journal article  |  2018  |  JAMA NEUROLOGY

IMPORTANCE: Neuroinflammation appears to be a key modulator of disease progression in amyotrophic lateral sclerosis (ALS) and ther..

Inclusion of BLIMP-1( ) effector regulatory T cells improves the Immunoscore in a cohort of New Zealand colorectal cancer patients: a pilot study

Kirsten A Ward-Hartstonge, John L McCall, Timothy R McCulloch, Ann-Kristin Kamps, Adam Girardin, Erika Cretney, Fran M Munro, Roslyn A Kemp

Journal article  |  2017  |  CANCER IMMUNOLOGY IMMUNOTHERAPY

Analysis of tumour-infiltrating T cells in colorectal cancer can predict disease-free survival. The Immunoscore, obtained by quant..

Effector Regulatory T Cell Differentiation and Immune Homeostasis Depend on the Transcription Factor Myb

Sheila Dias, Angela D'Amico, Erika Cretney, Yang Liao, Julie Tellier, Christine Bruggeman, Francisca F Almeida, Jamie Leahy, Gabrielle T Belz, Gordon K Smyth, Wei Shi, Stephen L Nutt

Journal article  |  2017  |  IMMUNITY

FoxP3-expressing regulatory T (Treg) cells are essential for maintaining immune homeostasis. Activated Treg cells undergo further ..

Th17 cell differentiation proceeds independently of IRF8

Dane M Newman, Patrick SK Leung, Tracy L Putoczki, Stephen L Nutt, Erika Cretney

Journal article  |  2016  |  IMMUNOLOGY AND CELL BIOLOGY

The transcriptional repressor/activator interferon regulatory factor 8 (IRF8) modulates the differentiation of a multitude of hema..

Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology

Marcela Montes de Oca, Rajiv Kumar, Fabian de labastida Rivera, Fiona H Amante, Meru Sheel, Rebecca J Faleiro, Patrick T Bunn, Shannon E Best, Lynette Beattie, Susanna S Ng, Chelsea L Edwards, Werner Muller, Erika Cretney, Stephen L Nutt, Mark J Smyth, Ashraful Haque, Geoffrey R Hill, Shyam Sundar, Axel Kallies, Christian R Engwerda

Journal article  |  2016  |  PLOS PATHOGENS

Tumor necrosis factor (TNF) is critical for controlling many intracellular infections, but can also contribute to inflammation. It..

Differentiation and function of Foxp3( ) effector regulatory T cells

Erika Cretney, Axel Kallies, Stephen L Nutt

Journal article  |  2013  |  TRENDS IN IMMUNOLOGY

Regulatory T (Treg) cells are essential for immunological tolerance and homeostasis. Although forkhead box (Fox)p3 is continually ..

Keeping memories alive

Gabrielle T Belz, Erika Cretney

Journal article  |  2013  |  FRONTIERS IN IMMUNOLOGY

The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells

Erika Cretney, Annie Xin, Wei Shi, Martina Minnich, Frederick Masson, Maria Miasari, Gabrielle T Belz, Gordon K Smyth, Meinrad Busslinger, Stephen L Nutt, Axel Kallies

Journal article  |  2011  |  NATURE IMMUNOLOGY

Regulatory T cells (T(reg) cells) are required for peripheral tolerance. Evidence indicates that T(reg) cells can adopt specialize..

Fatal Hepatitis Mediated by Tumor Necrosis Factor TNF alpha Requires Caspase-8 and Involves the BH3-Only Proteins Bid and Bim

Thomas Kaufmann, Philipp J Jost, Marc Pellegrini, Hamsa Puthalakath, Raffi Gugasyan, Steve Gerondakis, Erika Cretney, Mark J Smyth, John Silke, Razq Hakem, Philippe Bouillet, Tak W Mak, Vishva M Dixit, Andreas Strasser

Journal article  |  2009  |  IMMUNITY

Apoptotic death of hepatocytes, a contributor to many chronic and acute liver diseases, can be a consequence of overactivation of ..