Nai Fu

STEM CELLS AND THE DIFFERENTIATION HIERARCHY IN MAMMARY GLAND DEVELOPMENT

Nai Yang Fu, Emma Nolan, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2020  |  PHYSIOLOGICAL REVIEWS

The mammary gland is a highly dynamic organ that undergoes profound changes within its epithelium during puberty and the reproduct..

Halting triple negative breast cancer by targeting PROCR

Nai Yang Fu, Jane E Visvader

Journal article  |  2019  |  CELL RESEARCH

Lgr(5 ) pericentral hepatocytes are self-maintained in normal liver regeneration and susceptible to hepatocarcinogenesis

Chow Hiang Ang, Shih Han Hsu, Fusheng Guo, Chong Teik Tan, Victor C Yu, Jane E Visvader, Pierce KH Chow, Nai Yang Fu

Journal article  |  2019  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging evidence suggests that hepatocytes are primarily maintained by self-renewal during normal liver homeostasis, as well as i..

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.

Anne C Rios, Bianca D Capaldo, François Vaillant, Bhupinder Pal, Ravian van Ineveld, Caleb A Dawson, Yunshun Chen, Emma Nolan, Nai Yang Fu, undefined 3DTCLSM Group, Felicity C Jackling, Sapna Devi, David Clouston, Lachlan Whitehead, Gordon K Smyth, Scott N Mueller, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2019  |  Cancer Cell

(Cancer Cell 35, 618–632.e1–e6; April 15, 2019) In the STAR Methods section of the originally published version of this article, t..

Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging

Anne C Rios, Bianca D Capaldo, Francois Vaillant, Bhupinder Pal, Ravian van Ineveld, Caleb A Dawson, Yunshun Chen, Emma Nolan, Nai Yang Fu, Felicity C Jackling, Sapna Devi, David Clouston, Lachlan Whitehead, Gordon K Smyth, Scott N Mueller, Geoffrey J Lindeman, Jane E Visvader, Jamie R Flynn, William M Palmer, Antony P Martin, et al.

Journal article  |  2019  |  CANCER CELL

Breast tumors are inherently heterogeneous, but the evolving cellular organization through neoplastic progression is poorly unders..

Foxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from Quiescence

Nai Yang Fu, Bhupinder Pal, Yunshun Chen, Felicity C Jackling, Michael Milevskiy, Francois Vaillant, Bianca D Capaldo, Fusheng Guo, Kevin H Liu, Anne C Rios, Nicholas Lim, Andrew J Kueh, David M Virshup, Marco J Herold, Haley O Tucker, Gordon K Smyth, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2018  |  DEVELOPMENTAL CELL

Long-lived quiescent mammary stem cells (MaSCs) are presumed to coordinate the dramatic expansion of ductal epithelium that occurs..

Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling

Bhupinder Pal, Yunshun Chen, Francois Vaillant, Paul Jamieson, Lavinia Gordon, Anne C Rios, Stephen Wilcox, Naiyang Fu, Kevin He Liu, Felicity C Jackling, Melissa J Davis, Geoffrey J Lindeman, Gordon K Smyth, Jane E Visvader

Journal article  |  2017  |  NATURE COMMUNICATIONS

The mammary epithelium comprises two primary cellular lineages, but the degree of heterogeneity within these compartments and thei..

Derivation of a robust mouse mammary organoid system for studying tissue dynamics

Paul R Jamieson, Johanna F Dekkers, Anne C Rios, Nai Yang Fu, Geoffrey J Lindeman, Jane E Visvader

Journal article  |  2017  |  DEVELOPMENT

Advances in stem cell research have enabled the generation of 'mini organs' or organoids that recapitulate phenotypic traits of th..

Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive

Nai Yang Fu, Anne C Rios, Bhupinder Pal, Charity W Law, Paul Jamieson, Ruijie Liu, Francois Vaillant, Felicity Jackling, Kevin He Liu, Gordon K Smyth, Geoffrey J Lindeman, Matthew E Ritchie, Jane E Visvader

Journal article  |  2017  |  NATURE CELL BIOLOGY

Despite accumulating evidence for a mammary differentiation hierarchy, the basal compartment comprising stem cells remains poorly ..

Lineage Tracing of Mammary Stem and Progenitor Cells

Anoeska AA van de Moosdijk, Nai Yang Fu, Anne C Rios, Jane E Visvader, Renee van Amerongen

Journal article  |  2017  |  MAMMARY GLAND DEVELOPMENT: METHODS AND PROTOCOLS

Lineage tracing analysis allows mammary epithelial cells to be tracked in their natural environment, thereby revealing cell fate a..