Susanne Heinzel

Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny

Mark R Dowling, Andrey Kan, Susanne Heinzel, Julia M Marchingo, Philip D Hodgkin, Edwin D Hawkins

Journal article  |  2018  |  Frontiers in Immunology

Multiplexed Division Tracking Dyes for Proliferation-Based Clonal Lineage Tracing

Miles B Horton, Giulio Prevedello, Julia M Marchingo, Jie HS Zhou, Ken R Duffy, Susanne Heinzel, Philip D Hodgkin

Journal article  |  2018  |  The Journal of Immunology

The regulation of lymphocyte activation and proliferation

Susanne Heinzel, Julia M Marchingo, Miles B Horton, Philip D Hodgkin

Journal article  |  2018  |  Current Opinion in Immunology

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia

M Waibel, SJ Vervoort, IY Kong, S Heinzel, KM Ramsbottom, BP Martin, ED Hawkins, RW Johnstone

Journal article  |  2018  |  Leukemia

Life and Death of Activated T Cells: How Are They Different from Naive T Cells?

Yifan Zhan, Emma M Carrington, Yuxia Zhang, Susanne Heinzel, Andrew M Lew

Journal article  |  2017  |  Frontiers in Immunology

Cognate antigen engagement on parenchymal cells stimulates CD8( ) T cell proliferation in situ

Robyn M Sutherland, Sarah L Londrigan, Jamie L Brady, Emma M Carrington, Julia M Marchingo, Susanne Heinzel, Philip D Hodgkin, Kate L Graham, Thomas W Kay, Yifan Zhan, Andrew M Lew

Journal article  |  2017  |  Nature Communications

Characterisation of mice lacking all functional isoforms of the pro-survival BCL-2 family member A1 reveals minor defects in the haematopoietic compartment

Robyn L Schenk, Selma Tuzlak, Emma M Carrington, Yifan Zhan, Susanne Heinzel, Charis E Teh, Daniel H Gray, Lin Tai, Andrew M Lew, Andreas Villunger, Andreas Strasser, Marco J Herold

Journal article  |  2017  |  Cell Death & Differentiation

A Myc-dependent division timer complements a cell-death timer to regulate T cell and B cell responses

Susanne Heinzel, Binh Giang Tran, Andrey Kan, Julia M Marchingo, Bryan K Lye, Lynn M Corcoran, Philip D Hodgkin

Journal article  |  2017  |  Nature Immunology

T-cell stimuli independently sum to regulate an inherited clonal division fate

JM Marchingo, G Prevedello, A Kan, S Heinzel, PD Hodgkin, KR Duffy

Journal article  |  2016  |  Nature Communications

German Society for Immunology and Australasian Society for Immunology joint Workshop 3(rd)-4(th) December 2015-Meeting report

Christian Kurts, Catherine Gottschalk, Sammy Bedoui, Susanne Heinzel, Dale Godfrey, Anselm Enders

Journal article  |  2016  |  European Journal of Immunology

Stochastic Measurement Models for Quantifying Lymphocyte Responses Using Flow Cytometry

Andrey Kan, Damian Pavlyshyn, John F Markham, Mark R Dowling, Susanne Heinzel, Jie HS Zhou, Julia M Marchingo, Philip D Hodgkin

Journal article  |  2016  |  PLOS ONE

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

Julia M Marchingo, Andrey Kan, Robyn M Sutherland, Ken R Duffy, Cameron J Wellard, Gabrielle T Belz, Andrew M Lew, Mark R Dowling, Susanne Heinzel, Philip D Hodgkin

Journal article  |  2014  |  Science

Stretched cell cycle model for proliferating lymphocytes

Mark R Dowling, Andrey Kan, Susanne Heinzel, Jie HS Zhou, Julia M Marchingo, Cameron J Wellard, John F Markham, Philip D Hodgkin

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals

Paul Koenen, Susanne Heinzel, Emma M Carrington, Lina Happo, Warren S Alexander, Jian-Guo Zhang, Marco J Herold, Clare L Scott, Andrew M Lew, Andreas Strasser, Philip D Hodgkin

Journal article  |  2013  |  Nature Communications

Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax (TM) polysaccharide adjuvant

David L Gordon, Dimitar Sajkov, Richard J Woodman, Yoshikazu Honda-Okubo, Manon MJ Cox, Susanne Heinzel, Nikolai Petrovsky

Journal article  |  2012  |  Vaccine

The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

Harukazu Suzuki, Alistair RR Forrest, Erik van Nimwegen, Carsten O Daub, Piotr J Balwierz, Katharine M Irvine, Timo Lassmann, Timothy Ravasi, Yuki Hasegawa, Michiel JL de Hoon, Shintaro Katayama, Kate Schroder, Piero Carninci, Yasuhiro Tomaru, Mutsumi Kanamori-Katayama, Atsutaka Kubosaki, Altuna Akalin, Yoshinari Ando, Erik Arner, Maki Asada, et al.

Journal article  |  2009  |  Nature Genetics

New-age vaccine adjuvants: Friend or foe?

N Petrovsky, S Heinzel, Y Honda, AB Lyons

Journal article  |  2007  |  BioPharm International

Immune activation in patients with irritable bowel syndrome

Tobias Liebregts, Birgit Adam, Christoph Bredack, Alexander Roth, Susanne Heinzel, Sue Lester, Sarah Downie-Doyle, Eric Smith, Paul Drew, Nicholas J Talley, Gerald Holtmann

Journal article  |  2007  |  Gastroenterology

Plasmacytoid DCs and cancer: a new role for an enigmatic cell

M Mohty, D Olive, A Gaugler

Journal article  |  2004  |  Trends in Immunology

CD1a in human cancers: a new role for an old molecule

B Coventry, S Heinzel

Journal article  |  2004  |  Trends in Immunology

Is CDI a involved in antitumour immune responses during carcinogenesis? Reply

BJ Coventry, S Heinzel

Journal article  |  2004  |  British Journal of Cancer

Is CDI a involved in antitumour immune responses during carcinogenesis?

F Cappello

Journal article  |  2004  |  British Journal of Cancer

Peptide HER2(776-788) represents a naturally processed broad MHC class II-restricted T cell epitope

R Sotiriadou, SA Perez, AD Gritzapis, P Sotiropoulou, H Echner, S Heinzel, A Mamalaki, G Pawelec, W Voelter, CN Baxevanis, M Papamichail

Journal article  |  2001  |  British Journal of Cancer

The self peptide annexin II (208-223) presented by dendritic cells sensitizes autologous CD4 T lymphocytes to recognize melanoma cells.

S Heinzel, D Rea, R Offringa, G Pawelec

Journal article  |  2001  |  Cancer Immunology, Immunotherapy

Annexin II is known to be over-expressed in different types of tumours. We show here that annexin II protein is expressed by melan..

Defensins are dominant HLA-DR-associated self-peptides from CD34(-) peripheral blood mononuclear cells of different tumor patients (plasmacytoma, chronic myeloid leukemia)

TM Halder, M Bluggel, S Heinzel, G Pawelec, HE Meyer, H Kalbacher

Journal article  |  2000  |  Blood

Escape mechanisms in tumor immunity: A year 2000 update

G Pawelec, S Heinzel, R Kiessling, L Muller, Q Ouyang, J Zeuthen

Journal article  |  2000  |  Critical Reviews in Oncogenesis

Tumour-specific MHC-class-II-restricted responses after in vitro sensitization to synthetic peptides corresponding to gp100 and Annexin II eluted from melanoma cells

K Li, M Adibzadeh, T Halder, H Kalbacher, S Heinzel, C Muller, J Zeuthen, G Pawelec

Journal article  |  1998  |  Cancer Immunology, Immunotherapy