Julie Sheridan

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.

Rushika C Wirasinha, Ainsley R Davies, Monika Srivastava, Julie M Sheridan, Xavier YX Sng, Ottavia M Delmonte, Kerry Dobbs, Khai L Loh, Lisa A Miosge, Cindy Eunhee Lee, Rochna Chand, Anna Chan, Jin Yan Yap, Michael D Keller, Karin Chen, Jamie Rossjohn, Nicole L La Gruta, Carola G Vinuesa, Hugh H Reid, Michail S Lionakis, et al.

Journal article  |  2021  |  Journal of Experimental Medicine

NF-κB2/p100 (p100) is an inhibitor of κB (IκB) protein that is partially degraded to produce the NF-κB2/p52 (p52) transcription fa..

A missense mutation in the MLKL brace region promotes lethal neonatal inflammation and hematopoietic dysfunction

Joanne M Hildebrand, Maria Kauppi, Ian J Majewski, Zikou Liu, Allison J Cox, Sanae Miyake, Emma J Petrie, Michael A Silk, Zhixiu Li, Maria C Tanzer, Gabriela Brumatti, Samuel N Young, Cathrine Hall, Sarah E Garnish, Jason Corbin, Michael D Stutz, Ladina Di Rago, Pradnya Gangatirkar, Emma C Josefsson, Kristin Rigbye, et al.

Journal article  |  2020  |  Nature Communications

MLKL is the essential effector of necroptosis, a form of programmed lytic cell death. We have isolated a mouse strain with a singl..

Isolation and Propagation of Mammary Epithelial Stem and Progenitor Cells.

Julie M Sheridan, Jane E Visvader

Journal article  |  2019  |  Methods in molecular biology (Clifton, N.J.)

Several methods of mammary gland dissociation have been described that utilize a combined strategy of mechanical and enzymatic dis..

A critical epithelial survival axis regulated by MCL-1 maintains thymic function in mice

Reema Jain, Julie M Sheridan, Antonia Policheni, Melanie Heinlein, Luke C Gandolfo, Grant Dewson, Gordon K Smyth, Stephen N Sansom, Nai Yang Fu, Jane E Visvader, Georg A Hollander, Andreas Strasser, Daniel HD Gray

Journal article  |  2017  |  Blood

Thymospheres Are Formed by Mesenchymal Cells with the Potential to Generate Adipocytes, but Not Epithelial Cells

Julie M Sheridan, Ashleigh Keown, Antonia Policheni, Siti NA Roesley, Noa Rivlin, Noam Kadouri, Matthew E Ritchie, Reema Jain, Jakub Abramson, Tracy SP Heng, Daniel HD Gray

Journal article  |  2017  |  Cell Reports

Combining multiple tools outperforms individual methods in gene set enrichment analyses

Monther Alhamdoosh, Milica Ng, Nicholas J Wilson, Julie M Sheridan, Huy Huynh, Michael J Wilson, Matthew E Ritchie

Journal article  |  2017  |  Bioinformatics

Easy and efficient ensemble gene set testing with EGSEA.

Monther Alhamdoosh, Charity W Law, Luyi Tian, Julie M Sheridan, Milica Ng, Matthew E Ritchie

Journal article  |  2017  |  F1000Research

Gene set enrichment analysis is a popular approach for prioritising the biological processes perturbed in genomic datasets. The Bi..

Linear ubiquitin chain assembly complex coordinates late thymic T-cell differentiation and regulatory T-cell homeostasis

Charis E Teh, Najoua Lalaoui, Reema Jain, Antonia N Policheni, Melanie Heinlein, Silvia Alvarez-Diaz, Julie M Sheridan, Eva Rieser, Stefanie Deuser, Maurice Darding, Hui-Fern Koay, Yifang Hu, Fiona Kupresanin, Lorraine A O'Reilly, Dale I Godfrey, Gordon K Smyth, Philippe Bouillet, Andreas Strasser, Henning Walczak, John Silke, et al.

Journal article  |  2016  |  NATURE COMMUNICATIONS

Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing

Andrew Keniry, Linden J Gearing, Natasha Jansz, Joy Liu, Aliaksei Z Holik, Peter F Hickey, Sarah A Kinkel, Darcy L Moore, Kelsey Breslin, Kelan Chen, Ruijie Liu, Catherine Phillips, Miha Pakusch, Christine Biben, Julie M Sheridan, Benjamin T Kile, Catherine Carmichael, Matthew E Ritchie, Douglas J Hilton, Marnie E Blewitt

Journal article  |  2016  |  Epigenetics & Chromatin

Reinforcing the 'gauntlet' of thymic negative selection via exosomal transfer of self-antigens

Julie Sheridan, Daniel Gray

Journal article  |  2015  |  Immunology & Cell Biology