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Dr

Wei Shi

Honorary
Medical Biology (W.E.H.I.)
computational biology
Bioinformatics
computer science
genomics
gene expression
microarray
next-generation sequencing
science & technology
life sciences & biomedicine
Wei Shi's Profile Picture
Dr

Wei Shi

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Dr Shi develops computational methods for analyzing high-throughput molecular data including next-gen sequencing data and microarray data.
Wei Shi's Profile Picture
Dr

Wei Shi

 

Research interest

NGS technologies provide single-nucleotide resolution in measuring molecular changes in cells, and they have fundamentally transformed medical research. However, a significant challenge for analysis of NGS data lies in the processing of massive volumes of read data.



We develop highly efficient and accurate algorithms for the analysis of NGS data, and these algorithms are implemented in easy-to-use software programs that have been used worldwide.

The methods we develop include:
- ‘Seed-and-vote’ read mapping for short and long NGS reads. - Detection of structural variants and complex indels in normal and cancer genomes. - Quantification of expression levels of genes, transcripts and exons.
Another arm of research in my lab is to use a genomic approach to investigate the differentiation of lymphocytes in our immune system. We collaborate with world-leading immunologists to profile global changes of gene expression during lymphocyte differentiation, and we aim to discover novel target genes for improved vaccine design and therapy.


www.wehi.edu.au/people/wei-shi

Scholarly Works

Displaying the 71 most recent scholarly works by Wei Shi.

Honours, Awards and Fellowships

2016

CSL Centenary Fellowship in Bioinformatics


1

Award

Credentials

Positions


Honorary

Medical Biology (W.E.H.I.)

Honorary

Computing And Information Systems

Education


Master of Science

Harbin Institute of Technology

Bachelor of Engineering

Harbin Institute of Technology

Doctor of Philosophy

Harbin Institute of Technology