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Dr

Samir Taoudi

Honorary
Medical Biology (W.E.H.I.)
science & technology
animals
life sciences & biomedicine
hematopoietic stem cells
agm region
mice
aorta
mouse embryo
embryo, mammalian
Samir Taoudi's Profile Picture
Dr

Samir Taoudi

 
Division
Medicine, Dentistry And Health Sciences
 
Primary Interest
Stem cells
Samir Taoudi's Profile Picture
Dr

Samir Taoudi

 

www.wehi.edu.au/people/samir-taoudi

Our laboratory studies blood stem cells, which can generate the diverse types of blood cells formed. The ability to sustain blood production throughout our lifetime is critical for our health.

Many diseases result from failures of normal blood cell formation.

Understanding how stem cells are produced and their behaviours are controlled is critical for our endeavours to produce stem cells tailored for therapeutic use. Deciphering the processes of blood stem cell formation is the focus of our laboratory.

Projects

Displaying the most recent project by Samir Taoudi.

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Identifying Molecular Regulators Of Haematopoietic Stem Cell Development

Blood stem cells are capable of making all types of mature blood cell whilst making new copies of themselves. These properties are essential..

2012 - 2015
Completed

1

Projects

Project Types

1

Research Grant

Scholarly Works

Displaying the 15 most recent scholarly works by Samir Taoudi.

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Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo

Jennifer Easterbrook, Stanislav Rybtsov, Sabrina Gordon-Keylock, Andrejs Ivanovs, Samir Taoudi, Richard A Anderson, Alexander Medvinsky

Journal article  |  2019  |  Stem Cell Reports

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NOTCHing down a win for megakaryocytes

Samir Taoudi

Journal article  |  2018  |  Blood

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High-Jaking the blood: resistance is fetal

Samir Taoudi

Journal article  |  2016  |  Blood

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Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells

Celine Souilhol, Christele Gonneau, Javier G Lendinez, Antoniana Batsivari, Stanislav Rybtsov, Heather Wilson, Lucia Morgado-Palacin, David Hills, Samir Taoudi, Jennifer Antonchuk, Suling Zhao, Alexander Medvinsky

Journal article  |  2016  |  Nature Communications

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Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

Kathryn S Potts, Tobias J Sargeant, Caleb A Dawson, Emma C Josefsson, Douglas J Hilton, Warren S Alexander, Samir Taoudi

Journal article  |  2015  |  Blood

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A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Kathryn S Potts, Tobias J Sargeant, John F Markham, Wei Shi, Christine Biben, Emma C Josefsson, Lachlan W Whitehead, Kelly L Rogers, Anna Liakhovitskaia, Gordon K Smyth, Benjamin T Kile, Alexander Medvinsky, Warren S Alexander, Douglas J Hilton, Samir Taoudi

Journal article  |  2014  |  Blood

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Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

Stanislav Rybtsov, Malgorzata Sobiesiak, Samir Taoudi, Celine Souilhol, Jordi Senserrich, Anna Liakhovitskaia, Andrejs Ivanovs, Jon Frampton, Suling Zhao, Alexander Medvinsky

Journal article  |  2011  |  Journal of Experimental Medicine

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Embryonic origin of the adult hematopoietic system: advances and questions

Alexander Medvinsky, Stanislav Rybtsov, Samir Taoudi

Journal article  |  2011  |  Development

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ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

Samir Taoudi, Thomas Bee, Adrienne Hilton, Kathy Knezevic, Julie Scott, Tracy A Willson, Caitlin Collin, Tim Thomas, Anne K Voss, Benjamin T Kile, Warren S Alexander, John E Pimanda, Douglas J Hilton

Journal article  |  2011  |  Genes & Development

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Hematopoietic stem cell activity in the Aorta-Gonad-Mesonephros region enhances after mid-day 11 of mouse development

Erin Taylor, Samir Taoudi, Alexander Medvinsky

Journal article  |  2010  |  The International Journal of Developmental Biology

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A Novel Method for the Generation of Reaggregated Organotypic Cultures That Permits Juxtaposition of Defined Cell Populations

Julie M Sheridan, Samir Taoudi, Alexander Medvinsky, C Clare Blackburn

Journal article  |  2009  |  genesis

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Extensive hematopoietic stem cell generation in the AGM region via maturation of VE-cadherin( )CD45( ) pre-definitive HSCs

Samir Taoudi, Christele Gonneau, Kate Moore, Julie M Sheridan, C Clare Blackburn, Erin Taylor, Alexander Medvinsky

Journal article  |  2008  |  Cell Stem Cell

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Analysis and manipulation of hematopoietic progenitor and stem cells from murine embryonic tissues.

Alexander Medvinsky, Samir Taoudi, Sandra Mendes, Elaine Dzierzak

Journal article  |  2008  |  Current Protocols in Stem Cell Biology

Hematopoietic development begins in several locations in the mammalian embryo: yolk sac, aorta-gonad-mesonephros region (AGM), and..

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Functional identification of the hematopoietic stem cell niche in the ventral domain of the embryonic dorsal aorta

Samir Taoudi, Alexander Medvinsky

Journal article  |  2007  |  Proceedings of the National Academy of Sciences

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Progressive divergence of definitive haematopoietic stem cells from the endothelial compartment does not depend on contact with the foetal liver

S Taoudi, AM Morrison, H Inoue, R Gribi, J Ure, A Medvinsky

Journal article  |  2005  |  Development

15

Scholarly Works

Keyword Analysis

Clinical Health (organs, Diseases and Abnormal Conditions)
Expanding Knowledge
Biochemistry and Cell Biology
Cardiovascular Medicine and Haematology
Genetics
Other Medical and Health Sciences

Credentials

Positions

Honorary

Medical Biology (W.E.H.I.)

Education

Doctor of Philosophy

The University of Edinburgh

Links