Samir Taoudi

Single-cell analyses reveal the clonal and molecular aetiology of Flt3L-induced emergency dendritic cell development

Dawn S Lin, Luyi Tian, Sara Tomei, Daniela Amann-Zalcenstein, Tracey M Baldwin, Tom S Weber, Jaring Schreuder, Olivia J Stonehouse, Jai Rautela, Nicholas D Huntington, Samir Taoudi, Matthew E Ritchie, Philip D Hodgkin, Ashley P Ng, Stephen L Nutt, Shalin H Naik

Journal article  |  2021  |  Nature Cell Biology

Regulation of haematopoietic stem and progenitor cell (HSPC) fate is crucial during homeostasis and under stress conditions. Here ..

A new lymphoid-primed progenitor marked byDach1downregulation identified with single cell multi-omics

Daniela Amann-Zalcenstein, Luyi Tian, Jaring Schreuder, Sara Tomei, Dawn S Lin, Kirsten A Fairfax, Jessica E Bolden, Mark D McKenzie, Andrew Jarratt, Adrienne Hilton, Jacob T Jackson, Ladina Di Rago, Matthew P McCormack, Carolyn A de Graaf, Olivia Stonehouse, Samir Taoudi, Warren S Alexander, Stephen L Nutt, Matthew E Ritchie, Ashley P Ng, et al.

Journal article  |  2020  |  Nature Immunology

A classical view of blood cell development is that multipotent hematopoietic stem and progenitor cells (HSPCs) become lineage-rest..

Membrane budding is a major mechanism of in vivo platelet biogenesis

Kathryn S Potts, Alison Farley, Caleb A Dawson, Joel Rimes, Christine Biben, Carolyn de Graaf, Margaret A Potts, Olivia J Stonehouse, Amandine Carmagnac, Pradnya Gangatirkar, Emma C Josefsson, Casey Anttila, Daniela Amann-Zalcenstein, Shalin Naik, Warren S Alexander, Douglas J Hilton, Edwin D Hawkins, Samir Taoudi

Journal article  |  2020  |  Journal of Experimental Medicine

How platelets are produced by megakaryocytes in vivo remains controversial despite more than a century of investigation. Megakaryo..

Analysis of the Spatiotemporal Development of Hematopoietic Stem and Progenitor Cells in the Early Human Embryo

Jennifer Easterbrook, Stanislav Rybtsov, Sabrina Gordon-Keylock, Andrejs Ivanovs, Samir Taoudi, Richard A Anderson, Alexander Medvinsky

Journal article  |  2019  |  Stem Cell Reports

NOTCHing down a win for megakaryocytes

Samir Taoudi

Journal article  |  2018  |  Blood

High-Jaking the blood: resistance is fetal

Samir Taoudi

Journal article  |  2016  |  Blood

Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells

Celine Souilhol, Christele Gonneau, Javier G Lendinez, Antoniana Batsivari, Stanislav Rybtsov, Heather Wilson, Lucia Morgado-Palacin, David Hills, Samir Taoudi, Jennifer Antonchuk, Suling Zhao, Alexander Medvinsky

Journal article  |  2016  |  Nature Communications

Mouse prenatal platelet-forming lineages share a core transcriptional program but divergent dependence on MPL

Kathryn S Potts, Tobias J Sargeant, Caleb A Dawson, Emma C Josefsson, Douglas J Hilton, Warren S Alexander, Samir Taoudi

Journal article  |  2015  |  Blood

A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo

Kathryn S Potts, Tobias J Sargeant, John F Markham, Wei Shi, Christine Biben, Emma C Josefsson, Lachlan W Whitehead, Kelly L Rogers, Anna Liakhovitskaia, Gordon K Smyth, Benjamin T Kile, Alexander Medvinsky, Warren S Alexander, Douglas J Hilton, Samir Taoudi

Journal article  |  2014  |  Blood

Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region

Stanislav Rybtsov, Malgorzata Sobiesiak, Samir Taoudi, Celine Souilhol, Jordi Senserrich, Anna Liakhovitskaia, Andrejs Ivanovs, Jon Frampton, Suling Zhao, Alexander Medvinsky

Journal article  |  2011  |  Journal of Experimental Medicine