Samir Taoudi

A Prox1 enhancer represses haematopoiesis in the lymphatic vasculature

Jan Kazenwadel, Parvathy Venugopal, Anna Oszmiana, John Toubia, Luis Arriola-Martinez, Virginia Panara, Sandra G Piltz, Chris Brown, Wanshu Ma, Andreas W Schreiber, Katarzyna Koltowska, Samir Taoudi, Paul Q Thomas, Hamish S Scott, Natasha L Harvey

Journal article  |  2023  |  NATURE

Transcriptional enhancer elements are responsible for orchestrating the temporal and spatial control over gene expression that is ..

In vivo clonal tracking reveals evidence of haemangioblast and haematomesoblast contribution to yolk sac haematopoiesis.

C Biben, TS Weber, KS Potts, J Choi, DC Miles, A Carmagnac, T Sargeant, CA de Graaf, KA Fennell, A Farley, OJ Stonehouse, MA Dawson, DJ Hilton, SH Naik, S Taoudi

Journal article  |  2023  |  Nat Commun

During embryogenesis, haematopoietic and endothelial lineages emerge closely in time and space. It is thought that the first blood..

Mesoderm-derived PDGFRA cells regulate the emergence of hematopoietic stem cells in the dorsal aorta.

Vashe Chandrakanthan, Prunella Rorimpandey, Fabio Zanini, Diego Chacon, Jake Olivier, Swapna Joshi, Young Chan Kang, Kathy Knezevic, Yizhou Huang, Qiao Qiao, Rema A Oliver, Ashwin Unnikrishnan, Daniel R Carter, Brendan Lee, Chris Brownlee, Carl Power, Robert Brink, Simon Mendez-Ferrer, Grigori Enikolopov, William Walsh, et al.

Journal article  |  2022  |  Nat Cell Biol

Mouse haematopoietic stem cells (HSCs) first emerge at embryonic day 10.5 (E10.5), on the ventral surface of the dorsal aorta, by ..

Cerebral vasculature exhibits dose-dependent sensitivity to thrombocytopenia that is limited to fetal/neonatal life

Alison M Farley, Merle Dayton, Christine Biben, Olivia Stonehouse, Antoine Terreaux, Samir Taoudi

Journal article  |  2022  |  BLOOD

Whether increasing platelet counts in fetal and neonatal alloimmune thrombocytopenia (FNAIT) is effective at preventing intracereb..

1003 – MEMBRANE BUDDING AS A MECHANISM OF PLATELET BIOGENESIS

Samir Taoudi

Journal article  |  2022  |  Experimental Hematology

Vaccine-induced immune thrombosis and thrombocytopenia syndrome following adenovirus-vectored severe acute respiratory syndrome coronavirus 2 vaccination: a novel hypothesis regarding mechanisms and implications for future vaccine development

Paul Monagle, Ashley P Ng, Matthew Linden, Vera Ignjatovic, Alison Farley, Samir Taoudi, Sant Rayn Pasricha, Joseph Torresi

Journal article  |  2021  |  IMMUNOLOGY AND CELL BIOLOGY

We hypothesize that thrombosis with thrombocytopenia syndrome recently described after administration of adenovirus-vectored vacci..

Severe thrombocytopenia is sufficient for fetal and neonatal intracerebral hemorrhage to occur

Alison Farley, Sarah Lloyd, Merle Dayton, Christine Biben, Olivia Stonehouse, Samir Taoudi

Journal article  |  2021  |  BLOOD

Intracerebral hemorrhage (ICH) has a devastating impact on the neonatal population. Whether thrombocytopenia is sufficient to caus..

3128 – SINGLE-CELL ANALYSIS OF FOETAL LIVER STEM AND PROGENITOR CELLS REVEALS IMMUNOPHENOTYPICALLY HIDDEN LONG-TERM RECONSTITUTING HSCS

Olivia Stonehouse, Christine Biben, Katie Fennell, Alexandra Garnham, Tom Weber, Samir Taoudi

Journal article  |  2021  |  Experimental Hematology

2017 – THE MESODERMAL LINEAGES OF THE YOLK SAC ARE SEEDED BY HAEMANGIOBLAST, HAEMATOMESOBLAST, AND MESENCHYMOANGIOBLAST PRECURSORS

Christine Biben, Tom Weber, Kathryn Potts, Jarny Choi, Denise Miles, Amandine Carmagnac, Tobias Sargent, Carolyn de Graaf, Katie Fennell, Alison Farley, Olivia Stonehouse, Mark Dawson, Douglas Hilton, Shalin Naik, Samir Taoudi

Journal article  |  2021  |  Experimental Hematology

3041 – TRANSCRIPTIONAL STEPS IN MEGAKARYOCYTE COMMITMENT AND MATURATION

AnneMarie Welch, Christine Biben, Carolyn de Graff, Doug Hilton, Maria Kauppi, Kerry Ramsay, Samir Taoudi

Journal article  |  2021  |  Experimental Hematology