Gaoqian Feng

Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives

Katherine O'Flaherty, Ricardo Ataide, Sophie G Zaloumis, Elizabeth A Ashley, Rosanna Powell, Gaoqian Feng, Linda Reiling, Arjen M Dondorp, Nicholas P Day, Mehul Dhorda, Rick M Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tinh Hien Tran, Ye Htut, Mayfong Mayxay, M Abul Faiz, James G Beeson, Francois Nosten, et al.

Journal article  |  2019  |  The Journal of Infectious Diseases

BACKGROUND: Antibodies to the blood-stages of malaria enhance parasite-clearance and antimalarial efficacy. The antibody subclass ..

IgM in human immunity to Plasmodium falciparum malaria

MJ Boyle, JA Chan, I Handayuni, L Reiling, G Feng, A Hilton, L Kurtovic, D Oyong, KA Piera, BE Barber, T William, DP Eisen, G Minigo, C Langer, DR Drew, F de Labastida Rivera, FH Amante, TN Williams, S Kinyanjui, K Marsh, et al.

Journal article  |  2019  |  Science Advances

Induction and decay of functional complement-fixing antibodies by the RTS,S malariavaccine in children, and a negative impact of malaria exposure

Liriye Kurtovic, Paul A Agius, Gaoqian Feng, Damien R Drew, Itziar Ubillos, Jahit Sacarlal, John J Aponte, Freya JI Fowkes, Carlota Dobano, James G Beeson

Journal article  |  2019  |  BMC Medicine

Targets of complement-fixing antibodies in protective immunity against malaria in children

Linda Reiling, Michelle J Boyle, Michael T White, Danny W Wilson, Gaoqian Feng, Rupert Weaver, D Herbert Opi, Kristina EM Persson, Jack S Richards, Peter M Siba, Freya JI Fowkes, Eizo Takashima, Takafumi Tsuboi, Ivo Mueller, James G Beeson

Journal article  |  2019  |  Nature Communications

Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells

Xi Zen Yap, Rachel J Lundie, Gaoqian Feng, Joanne Pooley, James G Beeson, Meredith O'Keeffe

Journal article  |  2019  |  Frontiers in Immunology

Challenges and strategies for developing efficacious and long-lasting malaria vaccines

James G Beeson, Liriye Kurtovic, Carlota Dobano, D Herbert Opi, Jo-Anne Chan, Gaoqian Feng, Michael F Good, Linda Reiling, Michelle J Boyle

Journal article  |  2019  |  Science Translational Medicine

Human Immunization With a Polymorphic Malaria Vaccine Candidate Induced Antibodies to Conserved Epitopes That Promote Functional Antibodies to Multiple Parasite Strains

Gaoqian Feng, Michelle J Boyle, Nadia Cross, Jo-Anne Chan, Linda Roiling, Faith Osier, Danielle Stanisic, Ivo Mueller, Robin F Anders, James S McCarthy, Jack S Richards, James G Beeson

Journal article  |  2018  |  The Journal of Infectious Diseases

Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children

Liriye Kurtovic, Marije C Behet, Gaoqian Feng, Linda Reiling, Kiprotich Chelimo, Arlene E Dent, Ivo Mueller, James W Kazura, Robert W Sauerwein, Freya JI Fowkes, James G Beeson

Journal article  |  2018  |  BMC Medicine

Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure

Aida Valmaseda, Eusebio Macete, Augusto Nhabomba, Caterina Guinovart, Pedro Aide, Azucena Bardaji, Quique Bassat, Tacilta Nhampossa, Sonia Maculuve, Aina Casellas, Llorenc Quinto, Sergi Sanz, Alfons Jimenez, Gaoqian Feng, Christine Langer, Linda Reiling, K Sony Reddy, Alok Pandey, Chetan E Chitnis, Virander S Chauhan, et al.

Journal article  |  2018  |  Clinical Infectious Diseases

Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children

Cleopatra K Mugyenyi, Salenna R Elliott, Xi Zen Yap, Gaoqian Feng, Philippe Boeuf, Gregory Fegan, Faith FH Osier, Freya JI Fowkes, Marion Avril, Thomas N Williams, Kevin Marsh, James G Beeson

Journal article  |  2017  |  The Journal of Infectious Diseases

Functional Antibodies and Protection against Blood-Stage Malaria

Andrew Teo, Gaoqian Feng, Graham V Brown, James G Beeson, Stephen J Rogerson

Journal article  |  2016  |  Trends in Parasitology

The association between naturally acquired IgG subclass specific antibodies to the PfRH5 invasion complex and protection from Plasmodium falciparum malaria

Rupert Weaver, Linda Reiling, Gaoqian Feng, Damien R Drew, Ivo Mueller, Peter M Siba, Takafumi Tsuboi, Jack S Richards, Freya JI Fowkes, James G Beeson

Journal article  |  2016  |  Scientific Reports

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

James G Beeson, Damien R Drew, Michelle J Boyle, Gaoqian Feng, Freya JI Fowkes, Jack S Richards

Journal article  |  2016  |  FEMS Microbiology Reviews

CD14(hi)CD16 monocytes phagocytose antibody-opsonised Plasmodium falciparum infected erythrocytes more efficiently than other monocyte subsets, and require CD16 and complement to do so

Jingling Zhou, Gaoqian Feng, James Beeson, P Mark Hogarth, Stephen J Rogerson, Yan Yan, Anthony Jaworowski

Journal article  |  2015  |  BMC Medicine

Background With more than 600,000 deaths from malaria, mainly of children under five years old and caused by infection with Plasmo..

Human Antibodies Fix Complement to Inhibit Plasmodium falciparum Invasion of Erythrocytes and Are Associated with Protection against Malaria

Michelle J Boyle, Linda Reiling, Gaoqian Feng, Christine Langer, Faith H Osier, Harvey Aspeling-Jones, Yik Sheng Cheng, Janine Stubbs, Kevin KA Tetteh, David J Conway, James S McCarthy, Ivo Muller, Kevin Marsh, Robin F Anders, James G Beeson

Journal article  |  2015  |  Immunity

Decreasing Malaria Prevalence and Its Potential Consequences for Immunity in Pregnant Women

Andrew Teo, Wina Hasang, Louise M Randall, Gaoqian Feng, Lauren Bell, Holger Unger, Christine Langer, James G Beeson, Peter M Siba, Ivo Mueller, Malcolm E Molyneux, Graham V Brown, Stephen J Rogerson

Journal article  |  2014  |  Journal of Infectious Diseases

Opsonic phagocytosis of Plasmodium falciparum merozoites: mechanism in human immunity and a correlate of protection against malaria

Faith HA Osier, Gaoqian Feng, Michelle J Boyle, Christine Langer, Jingling Zhou, Jack S Richards, Fiona J McCallum, Linda Reiling, Anthony Jaworowski, Robin F Anders, Kevin Marsh, James G Beeson

Journal article  |  2014  |  BMC Medicine

The Effects of Malaria and Intermittent Preventive Treatment During Pregnancy on Fetal Anemia in Malawi

Elizabeth T Rogawski, Ebbie Chaluluka, Malcolm E Molyneux, Gaoqian Feng, Stephen J Rogerson, Steven R Meshnick

Journal article  |  2012  |  Clinical Infectious Diseases

Intermittent Preventive Treatment in Pregnancy With Sulfadoxine-Pyrimethamine: The Times They Are A-Changin' Reply

Steve M Taylor, Alejandro L Antonia, Victor Mwapasa, Gaoqian Feng, Malcolm E Molyneux, Feiko O ter Kuile, Steven R Meshnick, Stephen J Rogerson

Journal article  |  2012  |  Clinical Infectious Diseases

Antenatal Receipt of Sulfadoxine-Pyrimethamine Does Not Exacerbate Pregnancy-Associated Malaria Despite the Expansion of Drug-Resistant Plasmodium falciparum: Clinical Outcomes From the QuEERPAM Study

Steve M Taylor, Alejandro L Antonia, Ebbie Chaluluka, Victor Mwapasa, Gaoqian Feng, Malcolm E Molyneux, Feiko O ter Kuile, Steven R Meshnick, Stephen J Rogerson

Journal article  |  2012  |  Clinical Infectious Diseases

Adaptive evolution and fixation of drug-resistant Plasmodium falciparum genotypes in pregnancy-associated malaria: 9-year results from the QuEERPAM study

Steve M Taylor, Alejandro Antonia, Gaoqian Feng, Victor Mwapasa, Ebbie Chaluluka, Malcolm Molyneux, Feiko O ter Kuile, Stephen J Rogerson, Steven R Meshnick

Journal article  |  2012  |  Infection Genetics and Evolution

Decreasing Burden of Malaria in Pregnancy in Malawian Women and Its Relationship to Use of Intermittent Preventive Therapy or Bed Nets

Gaoqian Feng, Julie A Simpson, Ebbie Chaluluka, Malcolm E Molyneux, Stephen J Rogerson

Journal article  |  2010  |  PLoS One

Antibodies to Variant Surface Antigens of Plasmodium falciparum-Infected Erythrocytes Are Associated with Protection from Treatment Failure and the Development of Anemia in Pregnancy

Gaoqian Feng, Elizabeth Aitken, Francisca Yosaatmadja, Linda Kalilani, Steven R Meshnick, Anthony Jaworowski, Julie A Simpson, Stephen J Rogerson

Journal article  |  2009  |  Journal of Infectious Diseases

Relationship between Human Immunodeficiency Virus Type 1 Coinfection, Anemia, and Levels and Function of Antibodies to Variant Surface Antigens in Pregnancy-Associated Malaria

Anthony Jaworowski, Liselle A Fernandes, Francisca Yosaatmadja, Gaoqian Feng, Victor Mwapasa, Malcolm E Molyneux, Steven R Meshnick, Jenny Lewis, Stephen J Rogerson

Journal article  |  2009  |  Clinical and Vaccine Immunology