Leonie Cann

The gamma H2AX DSB marker may not be a suitable biodosimeter to measure the biological MRT valley dose

Jessica A Ventura, Jacqueline F Donoghue, Cameron J Nowell, Leonie M Cann, Liam RJ Day, Lloyd ML Smyth, Helen B Forrester, Peter AW Rogers, Jeffrey C Crosbie

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

PURPOSE: γH2AX biodosimetry has been proposed as an alternative dosimetry method for microbeam radiation therapy (MRT) because con..

Elucidating the role of long intergenic non-coding RNA 339 in human endometrium and endometriosis

Sarah J Holdsworth-Carson, Molly Churchill, Jacqueline F Donoghue, Sally Mortlock, Jenny N Fung, Clare Sloggett, Jessica Chung, Leonie Cann, Wan Tinn Teh, Katie-Rose Campbell, Rodney Luwor, Martin Healey, Grant Montgomery, Jane E Girling, Peter AW Rogers

Journal article  |  2021  |  MOLECULAR HUMAN REPRODUCTION

Endometriosis is a complex disease, influenced by genetic factors. Genetic markers associated with endometriosis exist at chromoso..

Endometrial uNK cell counts do not predict successful implantation in an IVF population

JF Donoghue, P Paiva, WT Teh, LM Cann, C Nowell, H Rees, S Bittinger, V Obers, JN Bulmer, C Stern, J Mcbain, PAW Rogers

Journal article  |  2019  |  HUMAN REPRODUCTION

STUDY QUESTION: Are uterine natural killer (uNK) cell numbers and their distribution relative to endometrial arterioles altered in..

Synchrotron microbeam radiotherapy evokes a different early tumor immunomodulatory response to conventional radiotherapy in EMT6.5 mammary tumors

Yuqing Yang, Agnieszka Swierczak, Mohammad Ibahim, Premila Paiva, Leonie Cann, Andrew W Stevenson, Jeffrey C Crosbie, Robin L Anderson, Peter AW Rogers

Journal article  |  2019  |  RADIOTHERAPY AND ONCOLOGY

BACKGROUND: Synchrotron microbeam radiation therapy (MRT) is a new, evolving form of radiotherapy that has potential for clinical ..

Expression and Cellular Localization of Endometriosis Risk Gene Long Intergenic Non-Coding RNA 339 (LINC00339).

Sarah J Holdsworth-Carson, Jane Girling, Leonie Cann, Martin Healey, Jenny N Fung, Grant Montgomery, Peter Rogers

Conference Proceedings  |  2019  |  REPRODUCTIVE SCIENCES

Uterine Natural Killer Cell Subpopulations and Their Proximity to Endometrial Arterioles Are Not Altered in Women with Recurrent Implantation Failure Following In Vitro Fertilisation.

Premila Paiva, Wan Tinn Teh, Leonie M Cann, Cameron Nowell, Jacqueline Donoghue, Judith N Bulmer, Catharyn Stern, John McBain, Peter A Rogers

Conference Proceedings  |  2017  |  REPRODUCTIVE SCIENCES

Histological changes in the umbilical artery following severe chorioamnionitis and funisitis may be indicative of early atherosclerosis

Anthony R Rafferty, Colleen D'Arcy, Leonie Cann, Jan Pyman, Peter Rogers, Peter G Davis, Cameron Nowell, David Burgner

Journal article  |  2017  |  PLACENTA

We investigated whether histological evidence of early atherosclerosis was present in the umbilical artery of 21 pregnancies compl..

Differences in the cellular composition of small versus large uterine fibroids

Sarah J Holdsworth-Carson, Dong Zhao, Leonie Cann, Sophie Bittinger, Cameron J Nowell, Peter AW Rogers

Journal article  |  2016  |  REPRODUCTION

Uterine fibroids are clonally derived from a single cell; however, despite being monoclonal, the cellular phenotypes that make up ..

Eosinophil-Associated Gene Pathways but not Eosinophil Numbers are Differentially Regulated between Synchrotron Microbeam Radiation Treatment and Synchrotron Broad-Beam Treatment by 48 Hours Postirradiation

MJ Ibahim, Y Yang, JC Crosbie, A Stevenson, L Cann, P Paiva, PA Rogers

Journal article  |  2016  |  RADIATION RESEARCH

Synchrotron microbeam radiation treatment (MRT) is a preclinical radiotherapy technique with considerable clinical promise, althou..

Genome-Wide Transcription Responses to Synchrotron Microbeam Radiotherapy

Carl N Sprung, Yuqing Yang, Helen B Forrester, Jason Li, Marina Zaitseva, Leonie Cann, Tina Restall, Robin L Anderson, Jeffrey C Crosbie, Peter AW Rogers

Journal article  |  2012  |  RADIATION RESEARCH

The majority of cancer patients achieve benefit from radiotherapy. A significant limitation of radiotherapy is its relatively low ..