Gillian Mitchell

Evaluation of implementation of risk management guidelines for carriers of pathogenic variants in mismatch repair genes: a nationwide audit of familial cancer clinics

B Meiser, R Kaur, J Kirk, A Morrow, M Peate, WKT Wong, E McPike, E Cops, C Dowson, R Austin, M Fine, L Thrupp, R Ward, F Macrae, JE Hiller, AH Trainer, G Mitchell

Journal article  |  2020  |  FAMILIAL CANCER

INTRODUCTION: This nationwide study assessed the impact of Lynch syndrome-related risk management guidelines on clinicians' recomm..

The predicted impact and cost-effectiveness of systematic testing of people with incident colorectal cancer for Lynch syndrome

Yoon-Jung Kang, James Killen, Michael Caruana, Kate Simms, Natalie Taylor, Ian M Frayling, Tristan Snowsill, Nicola Huxley, Veerle MH Coupe, Suzanne Hughes, Victoria Freeman, Alex Boussioutas, Alison H Trainer, Robyn L Ward, Gillian Mitchell, Finlay A Macrae, Karen Canfell

Journal article  |  2020  |  MEDICAL JOURNAL OF AUSTRALIA

OBJECTIVES: To evaluate the health impact and cost-effectiveness of systematic testing for Lynch syndrome (LS) in people with inci..

Cost-effectiveness of long-term clinical management of BRCA pathogenic variant carriers

Lara Petelin, Lucinda Hossack, Mary Shanahan, Gillian Mitchell, Danny Liew, Paul A James, Alison H Trainer

Journal article  |  2020  |  GENETICS IN MEDICINE

PURPOSE: Women who inherit a BRCA1 or BRCA2 pathogenic variant are at high risk of developing breast and ovarian cancer. Evidence ..

Pathways to a cancer-free future: a protocol for modelled evaluations to minimise the future burden of colorectal cancer in Australia

Eleonora Feletto, Jie-Bin Lew, Joachim Worthington, Emily He, Michael Caruana, Katherine Butler, Harriet Hui, Natalie Taylor, Emily Banks, Karen Barclay, Kate Broun, Alison Butt, Rob Carter, Jeff Cuff, Anita Dessaix, Hooi Ee, Jon Emery, Ian M Frayling, Paul Grogan, Carol Holden, et al.

Journal article  |  2020  |  BMJ OPEN

INTRODUCTION: With almost 50% of cases preventable and the Australian National Bowel Cancer Screening Program in place, colorectal..

A Microsimulation Model for Evaluating the Effectiveness of Cancer Risk Management for BRCA Pathogenic Variant Carriers: miBRovaCAre

Lara Petelin, Lucinda Hossack, Gillian Mitchell, Danny Liew, Alison H Trainer, Paul A James

Journal article  |  2019  |  VALUE IN HEALTH

OBJECTIVES: To develop a validated model for evaluating the real-world effectiveness of long-term clinical management strategies f..

Cancer screening in Australia: future directions in melanoma, Lynch syndrome, and liver, lung and prostate cancers

Marianne F Weber, Henry M Marshall, Nicole Rankin, Stephen Duffy, Kwun M Fong, Kate Dunlop, Lauren Humphreys, Amelia K Smit, Anne E Cust, Natalie Taylor, Gillian Mitchell, Yoon-Jung Kang, Kathy Tucker, Mark Jenkins, Finlay Macrae, Ian Lockart, Mark Danta, Bruce K Armstrong, Megan Howe

Journal article  |  2019  |  PUBLIC HEALTH RESEARCH & PRACTICE

While Australia now has well-established national screening programs for breast, bowel and cervical cancers, research continues in..

Comparing theory and non-theory based implementation approaches to improving referral practices in cancer genetics: a cluster randomised trial protocol

April Morrow, Emily Hogden, Yoon-Jung Kang, Julia Steinberg, Karen Canfell, Michael J Solomon, James G Kench, Anthony J Gill, Tim Shaw, Nicholas Pachter, Bonny Parkinson, Luke Wolfenden, Gillian Mitchell, Finlay Macrae, Kathy Tucker, Natalie Taylor

Journal article  |  2019  |  TRIALS

BACKGROUND: Lynch syndrome (LS) is an inherited, cancer predisposition syndrome associated with an increased risk of colorectal, e..

Assessing the medical workforces perceived barriers to the prescription of risk-reducing medication for women at high-risk of breast cancer

Sarah Sutherland, Bettina Meiser, Rajneesh Kaur, Gillian Mitchell, Judy Kirk, Michelle Peate, WK Tim Wong, Annabel Goodwin

Journal article  |  2019  |  BREAST JOURNAL

This study aims to determine the attitudes and barriers of Australian oncology health professionals towards using tamoxifen as a b..

Current mismatch repair deficiency tumor testing practices and capabilities: A survey of Australian pathology providers

Lyon Mascarenhas, Susan Shanley, Gillian Mitchell, Amanda B Spurdle, Finlay Macrae, Nicholas Pachter, Daniel D Buchanan, Robyn L Ward, Stephen Fox, Elaine Duxbury, Rebecca Driessen, Alex Boussioutas

Journal article  |  2018  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

AIM & METHODS: An electronic survey of the Royal College of Pathologists of Australasia accredited pathology services was conducte..

Cost-effectiveness and comparative effectiveness of cancer risk management strategies in BRCA1/2 mutation carriers: a systematic review

Lara Petelin, Alison H Trainer, Gillian Mitchell, Danny Liew, Paul A James

Journal article  |  2018  |  GENETICS IN MEDICINE

PURPOSE: To review the evidence for the effectiveness and cost-effectiveness of cancer risk management interventions for BRCA carr..