Freya Fowkes

Multi-functional antibodies are induced by the RTS,S malaria vaccine and associated with protection in a phase I/IIa trial.

Liriye Kurtovic, Tanmaya Atre, Gaoqian Feng, Bruce D Wines, Jo-Anne Chan, Michelle J Boyle, Damien R Drew, P Mark Hogarth, Freya JI Fowkes, Elke S Bergmann-Leitner, James G Beeson

Journal article  |  2020  |  The Journal of Infectious Diseases

BACKGROUND: RTS,S is the leading malaria vaccine candidate, but only confers partial efficacy against malaria in children. RTS,S i..

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3 alpha and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M

Damian A Oyong, Danny W Wilson, Bridget E Barber, Timothy William, Jianlin Jiang, Mary R Galinski, Freya JI Fowkes, Matthew J Grigg, James G Beeson, Nicholas M Anstey, Michelle J Boyle

Journal article  |  2019  |  The Journal of Infectious Diseases

BACKGROUND: Complement-fixing antibodies are important mediators of protection against Plasmodium falciparum malaria. However, com..

Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives

Katherine O'Flaherty, Ricardo Ataide, Sophie G Zaloumis, Elizabeth A Ashley, Rosanna Powell, Gaoqian Feng, Linda Reiling, Arjen M Dondorp, Nicholas P Day, Mehul Dhorda, Rick M Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tinh Hien Tran, Ye Htut, Mayfong Mayxay, M Abul Faiz, James G Beeson, Francois Nosten, et al.

Journal article  |  2019  |  The Journal of Infectious Diseases

BACKGROUND: Antibodies to the blood-stages of malaria enhance parasite-clearance and antimalarial efficacy. The antibody subclass ..

IgM in human immunity to Plasmodium falciparum malaria

MJ Boyle, JA Chan, I Handayuni, L Reiling, G Feng, A Hilton, L Kurtovic, D Oyong, KA Piera, BE Barber, T William, DP Eisen, G Minigo, C Langer, DR Drew, F de Labastida Rivera, FH Amante, TN Williams, S Kinyanjui, K Marsh, et al.

Journal article  |  2019  |  Science Advances

Understanding the interactions between iron supplementation, infectious disease and adverse birth outcomes is essential to guide public health recommendations

Freya JI Fowkes, Eliza Davidson, Paul A Agius, James G Beeson

Journal article  |  2019  |  BMC Medicine

UNINTENDED PREGNANCY AND FAMILY PLANNING USE AMONG ANTENATAL ATTENDEES IN EAST NEW BRITAIN, PAPUA NEW GUINEA

Elizabeth Peach, Chris Morgan, Michelle Scoullar, Freya Fowkes, Elissa Kennedy, Stanley Luchters, Andrew Vallely, Lisa Vallely, Angela Kelly, Leanne Robinson, Brendan Crabb, Peter Siba, William Pomat, JG Beeson

Conference Proceedings  |  2019  |  INTERNAL MEDICINE JOURNAL

Antibody Targets on the Surface of Plasmodium falciparum-Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children

Jo-Anne Chan, Michelle J Boyle, Kerryn A Moore, Linda Reiling, Zaw Lin, Wina Hasang, Marion Avril, Laurens Manning, Ivo Mueller, Moses Laman, Timothy Davis, Joseph D Smith, Stephen J Rogerson, Julie A Simpson, Freya JI Fowkes, James G Beeson

Journal article  |  2019  |  The Journal of Infectious Diseases

Induction and decay of functional complement-fixing antibodies by the RTS,S malariavaccine in children, and a negative impact of malaria exposure

Liriye Kurtovic, Paul A Agius, Gaoqian Feng, Damien R Drew, Itziar Ubillos, Jahit Sacarlal, John J Aponte, Freya JI Fowkes, Carlota Dobano, James G Beeson

Journal article  |  2019  |  BMC Medicine

Targets of complement-fixing antibodies in protective immunity against malaria in children

Linda Reiling, Michelle J Boyle, Michael T White, Danny W Wilson, Gaoqian Feng, Rupert Weaver, D Herbert Opi, Kristina EM Persson, Jack S Richards, Peter M Siba, Freya JI Fowkes, Eizo Takashima, Takafumi Tsuboi, Ivo Mueller, James G Beeson

Journal article  |  2019  |  Nature Communications

THE EFFECTIVENESS OF REPELLENT DELIVERED THROUGH VILLAGE HEALTH VOLUNTEERS ON MALARIA INCIDENCE IN SOUTHEAST MYANMAR: A STEPPED-WEDGE CLUSTER-RANDOMIZED CONTROLLED TRIAL

Paul Agius, Win Han Oo, Naanki Pasricha, Katherine O'Flaherty, Kyaw Zayar Aung, Aung Thi, Myat Mon Thein, Nyi Nyi Zaw, Htin Kyaw Thu, Wai Yan Min Htay, Aung Paing Soe, Nicole Romero, Zahra Razook, Alyssa Barry, Angela Devine, Julie Simpson, Brendan S Crabb, James G Beeson, Julia Cutts, Freya J Fowkes

Conference Proceedings  |  2019  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Effectiveness of repellent delivered through village health volunteers on malaria incidence in villages in South-East Myanmar: a stepped-wedge cluster-randomised controlled trial protocol

Win Han Oo, Julia C Cutts, Paul A Agius, Kyaw Zayar Aung, Poe Poe Aung, Thi Aung, Nyi Nyi Zaw, Htin Kyaw Thu, Wai Yan Min Htay, Ricardo Ataide, Katherine O'Flaherty, Ai Pao Yawn, Aung Paing Soe, James G Beeson, Brendan Crabb, Naanki Pasricha, Freya JI Fowkes

Journal article  |  2018  |  BMC Infectious Diseases

In Silico Investigation of the Decline in Clinical Efficacy of Artemisinin Combination Therapies Due to Increasing Artemisinin and Partner Drug Resistance

Sophie G Zaloumis, Pengxing Cao, Saber Dini, Miles P Davenport, Deborah Cromer, David S Khoury, Freya JI Fowkes, James M McCaw, Julie A Simpson

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling

Saber Dini, Sophie Zaloumis, Pengxing Cao, Ric N Price, Freya J Fowkes, E Rob W van der Pluijm, James M McCaw, Julie A Simpson

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Iron deficiency during pregnancy is associated with a reduced risk of adverse birth outcomes in a malaria-endemic area in a longitudinal cohort study

Freya JI Fowkes, Kerryn A Moore, D Herbert Opi, Julie A Simpson, Freya Langham, Danielle I Stanisic, Alice Ura, Christopher L King, Peter M Siba, Ivo Mueller, Stephen J Rogerson, James G Beeson

Journal article  |  2018  |  BMC MEDICINE

Implications of population-level immunity for the emergence of artemisinin-resistant malaria: a mathematical model

Nick Scott, Ricardo Ataide, David P Wilson, Margaret Hellard, Ric N Price, Julie A Simpson, Freya J Fowkes

Journal article  |  2018  |  Malaria Journal

Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children

Liriye Kurtovic, Marije C Behet, Gaoqian Feng, Linda Reiling, Kiprotich Chelimo, Arlene E Dent, Ivo Mueller, James W Kazura, Robert W Sauerwein, Freya JI Fowkes, James G Beeson

Journal article  |  2018  |  BMC Medicine

Anopheles Salivary Biomarker as a Proxy for Estimating Plasmodium falciparum Malaria Exposure on the Thailand-Myanmar Border

Phubeth Ya-Umphan, Dominique Cerqueira, Gilles Cottrell, Daniel M Parker, Freya JI Fowkes, Francois Nosten, Vincent Corbel

Journal article  |  2018  |  The American Journal of Tropical Medicine and Hygiene

A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum

Pengxing Cao, Nectarios Klonis, Sophie Zaloumis, Con Dogovski, Stanley C Xie, Sompob Saralamba, Lisa J White, Freya JI Fowkes, Leann Tilley, Julie A Simpson, James M McCaw

Journal article  |  2017  |  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Patterns of protective associations differ for antibodies to &ITP&IT. &ITfalciparum&IT-infected erythrocytes and merozoites in immunity against malaria in children

Jo-Anne Chan, Danielle Stanisic, Michael F Duffy, Leanne J Robinson, Enmoore Lin, James W Kazura, Christopher L King, Peter M Siba, Freya J Fowkes, Ivo Mueller, James G Beeson

Journal article  |  2017  |  European Journal of Immunology

Quantification of the association between malaria in pregnancy and stillbirth: a systematic review and meta-analysis

Kerryn A Moore, Julie A Simpson, Michelle JL Scoullar, Rose McGready, Freya JI Fowkes

Journal article  |  2017  |  The Lancet Global Health

P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission

Alistair RD McLean, Danielle Stanisic, Rose McGready, Kesinee Chotivanich, Caroline Clapham, Francesca Baiwog, Mupawjay Pimanpanarak, Peter Siba, Ivo Mueller, Christopher L King, Francois Nosten, James G Beeson, Stephen Rogerson, Julie A Simpson, Freya JI Fowkes

Journal article  |  2017  |  PLOS ONE

Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children

Cleopatra K Mugyenyi, Salenna R Elliott, Xi Zen Yap, Gaoqian Feng, Philippe Boeuf, Gregory Fegan, Faith FH Osier, Freya JI Fowkes, Marion Avril, Thomas N Williams, Kevin Marsh, James G Beeson

Journal article  |  2017  |  The Journal of Infectious Diseases

Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study

Ricardo Ataide, Rosanna Powell, Kerryn Moore, Alistair McLean, Aung Pyae Phyo, Shalini Nair, Marina White, Tim J Anderson, James G Beeson, Julie A Simpson, Francois Nosten, Freya JI Fowkes

Journal article  |  2017  |  The Journal of Infectious Diseases

Influence of the number and timing of malaria episodes during pregnancy on prematurity and small-for-gestational-age in an area of low transmission

Kerryn A Moore, Julie A Simpson, Jacher Wiladphaingern, Aung Myat Min, Mupawjay Pimanpanarak, Moo Kho Paw, Jathee Raksuansak, Sasithon Pukrittayakamee, Freya JI Fowkes, Nicholas J White, Francois Nosten, Rose McGready

Journal article  |  2017  |  BMC Medicine

Mediation of the effect of malaria in pregnancy on stillbirth and neonatal death in an area of low transmission: observational data analysis

Kerryn A Moore, Freya JI Fowkes, Jacher Wiladphaingern, Nan San Wai, Moo Kho Paw, Mupawjay Pimanpanarak, Verena I Carrara, Jathee Raksuansak, Julie A Simpson, Nicholas J White, Francois Nosten, Rose McGready

Journal article  |  2017  |  BMC Medicine

Immunity as a predictor of anti-malarial treatment failure: a systematic review

Katherine O'Flaherty, Julia Maguire, Julie A Simpson, Freya JI Fowkes

Journal article  |  2017  |  Malaria Journal

Differing rates of antibody acquisition to merozoite antigens in malaria: implications for immunity and surveillance

Fiona J McCallum, Kristina EM Persson, Freya JI Fowkes, Linda Reiling, Cleopatra K Mugyenyi, Jack S Richards, Julie A Simpson, Thomas N Williams, Paul R Gilson, Anthony N Hodder, Paul R Sanders, Robin F Anders, David L Narum, Chetan Chitnis, Brendan S Crabb, Kevin Marsh, James G Beeson

Journal article  |  2017  |  Journal of Leukocyte Biology

Host immunity to Plasmodium falciparum and the assessment of emerging artemisinin resistance in a multinational cohort

Ricardo Ataide, Elizabeth A Ashley, Rosanna Powell, Jo-Anne Chan, Michael J Malloy, Katherine O'Flaherty, Eizo Takashima, Christine Langer, Takafumi Tsuboi, Arjen M Dondorp, Nicholas P Day, Mehul Dhorda, Rick M Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tinh Hien Tran, Ye Htut, Mayfong Mayxay, M Abul Faiz, et al.

Journal article  |  2017  |  Proceedings of the National Academy of Sciences

Recent insights into humoral immunity targeting Plasmodium falciparum and Plasmodium vivax malaria

Michelle J Boyle, Linda Reiling, Faith H Osier, Freya JI Fowkes

Journal article  |  2017  |  International Journal for Parasitology

Inhibition of placental mTOR signaling provides a link between placental malaria and reduced birthweight

Kris Genelyn Dimasuay, Elizabeth H Aitken, Fredrick Rosario, Madi Njie, Jocelyn Glazier, Stephen J Rogerson, Freya JI Fowkes, James G Beeson, Theresa Powell, Thomas Jansson, Philippe Boeuf

Journal article  |  2017  |  BMC MEDICINE

Antibody Responses to Plasmodium falciparum and Plasmodium vivax and Prospective Risk of Plasmodium spp. Infection Postpartum

Alistair RD McLean, Machteld Boel, Rose McGready, Ricardo Ataide, Damien Drew, Takafumi Tsuboi, James G Beeson, Francois Nosten, Julie A Simpson, Freya JI Fowkes

Journal article  |  2017  |  The American Journal of Tropical Medicine and Hygiene

Achieving development goals for HIV, tuberculosis and malaria in sub-Saharan Africa through integrated antenatal care: barriers and challenges

Freya JI Fowkes, Bridget L Draper, Margaret Hellard, Mark Stoove

Journal article  |  2016  |  BMC Medicine

Association between malaria immunity and pregnancy outcomes among Malawian pregnant women receiving nutrient supplementation

Upeksha P Chandrasiri, Freya JI Fowkes, James G Beeson, Jack S Richards, Steve Kamiza, Kenneth Maleta, Per Ashorn, Stephen J Rogerson

Journal article  |  2016  |  MALARIA JOURNAL

A single point in protein trafficking by Plasmodium falciparum determines the expression of major antigens on the surface of infected erythrocytes targeted by human antibodies

Jo-Anne Chan, Katherine B Howell, Christine Langer, Alexander G Maier, Wina Hasang, Stephen J Rogerson, Michaela Petter, Joanne Chesson, Danielle I Stanisic, Michael F Duffy, Brian M Cooke, Peter M Siba, Ivo Mueller, Peter C Bull, Kevin Marsh, Freya JI Fowkes, James G Beeson

Journal article  |  2016  |  CELLULAR AND MOLECULAR LIFE SCIENCES

A malaria vaccine in children with HIV

James G Beeson, Freya JI Fowkes

Journal article  |  2016  |  The Lancet Infectious Diseases

The association between naturally acquired IgG subclass specific antibodies to the PfRH5 invasion complex and protection from Plasmodium falciparum malaria

Rupert Weaver, Linda Reiling, Gaoqian Feng, Damien R Drew, Ivo Mueller, Peter M Siba, Takafumi Tsuboi, Jack S Richards, Freya JI Fowkes, James G Beeson

Journal article  |  2016  |  Scientific Reports

Antibody responses to Plasmodium falciparum and Plasmodium vivax blood-stage and sporozoite antigens in the postpartum period

Alistair RD McLean, Machteld E Boel, Rose McGready, Ricardo Ataide, Damien Drew, Takafumi Tsuboi, James G Beeson, Francois Nosten, Julie A Simpson, Freya JI Fowkes

Journal article  |  2016  |  Scientific Reports

Water, Sanitation, and Hygiene Facilities and Hygiene Practices Associated with Diarrhea and Vomiting in Monastic Schools, Myanmar

Emma RN Weaver, Paul A Agius, Hilary Veale, Karl Dorning, Thein T Hlang, Poe P Aung, Freya JI Fowkes, Margaret E Hellard

Journal article  |  2016  |  The American Journal of Tropical Medicine and Hygiene

Differences in PfEMP1s recognized by antibodies from patients with uncomplicated or severe malaria

Michael F Duffy, Rintis Noviyanti, Takafumi Tsuboi, Zhi-Ping Feng, Leily Trianty, Boni F Sebayang, Eizo Takashima, Fransisca Sumardy, Daniel A Lampah, Louise Turner, Thomas Lavstsen, Freya JI Fowkes, Peter Siba, Stephen J Rogerson, Thor G Theander, Jutta Marfurt, Ric N Price, Nicholas M Anstey, Graham V Brown, Anthony T Papenfuss

Journal article  |  2016  |  MALARIA JOURNAL

Merozoite surface proteins in red blood cell invasion, immunity and vaccines against malaria

James G Beeson, Damien R Drew, Michelle J Boyle, Gaoqian Feng, Freya JI Fowkes, Jack S Richards

Journal article  |  2016  |  FEMS Microbiology Reviews

Safety of artemisinins in first trimester of prospectively followed pregnancies: an observational study

Kerryn A Moore, Julie A Simpson, Moo Kho Paw, Mupawjay Pimanpanarak, Jacher Wiladphaingern, Marcus J Rijken, Podjanee Jittamala, Nicholas J White, Freya JI Fowkes, Francois Nosten, Rose McGready

Journal article  |  2016  |  The Lancet Infectious Diseases

Maternal-foetal transfer of Plasmodium falciparum and Plasmodium vivax antibodies in a low transmission setting

SC Charnaud, R McGready, A Herten-Crabb, R Powell, A Guy, C Langer, JS Richards, PR Gilson, K Chotivanich, T Tsuboi, DL Narum, M Pimanpanarak, JA Simpson, JG Beeson, F Nosten, FJI Fowkes

Journal article  |  2016  |  Scientific Reports

Parasite Strain, Host Immunity, and Circulating Blood Cells with Dead Parasites: Why Predicting Malaria Parasite Clearance Is Not a Simple Task

J Simpson, J McCaw, FJ Fowkes

Journal article  |  2016  |  Antimicrobial Agents and Chemotherapy

Immunity to malaria in an era of declining malaria transmission

Freya JI Fowkes, Philippe Boeuf, James G Beeson

Journal article  |  2016  |  Parasitology

Presenting parasitological data: the good, the bad and the error bar

Sophie G Zaloumis, Freya JI Fowkes, Alysha De Livera, Julie A Simpson

Journal article  |  2015  |  Parasitology

Malaria eradication and elimination: views on how to translate a vision into reality

Marcel Tanner, Brian Greenwood, Christopher JM Whitty, Evelyn K Ansah, Ric N Price, Arjen M Dondorp, Lorenz von Seidlein, J Kevin Baird, James G Beeson, Freya JI Fowkes, Janet Hemingway, Kevin Marsh, Faith Osier

Journal article  |  2015  |  BMC Medicine

Malaria and immunity during pregnancy and postpartum: a tale of two species

ARD Mclean, R Ataide, JA Simpson, JG Beeson, FJI Fowkes

Journal article  |  2015  |  Parasitology

Estimating Gestational Age in Late Presenters to Antenatal Care in a Resource-Limited Setting on the Thai-Myanmar Border

Kerryn A Moore, Julie A Simpson, Kyla H Thomas, Marcus J Rijken, Lisa J White, Saw Lu Moo Dwell, Moo Kho Paw, Jacher Wiladphaingern, Sasithon Pukrittayakamee, Francois Nosten, Freya JI Fowkes, Rose McGready

Journal article  |  2015  |  PLOS ONE

The impact of lipid-based nutrient supplementation on anti-malarial antibodies in pregnant women in a randomized controlled trial

Upeksha P Chandrasiri, Freya JI Fowkes, Jack S Richards, Christine Langer, Yue-Mei Fan, Steve M Taylor, James G Beeson, Kathryn G Dewey, Kenneth Maleta, Per Ashorn, Stephen J Rogerson

Journal article  |  2015  |  MALARIA JOURNAL

Maximizing antimalarial efficacy and the importance of dosing strategies

James G Beeson, Philippe Boeuf, Freya JI Fowkes

Journal article  |  2015  |  BMC Medicine

Plasmodium vivax Malaria Challenges in diagnosis, treatment and elimination

James G Beeson, Cindy S Chu, Jack S Richards, Francois Nosten, Freya JI Fowkes

Journal article  |  2015  |  The Pediatric Infectious Disease Journal

Risk factors for malaria and adverse birth outcomes in a prospective cohort of pregnant women resident in a high malaria transmission area of Papua New Guinea

Danielle I Stanisic, Kerryn A Moore, Francesca Baiwog, Alice Ura, Caroline Clapham, Christopher L King, Peter M Siba, James G Beeson, Ivo Mueller, Freya J Fowkes, Stephen J Rogerson

Journal article  |  2015  |  Transactions of The Royal Society of Tropical Medicine and Hygiene

Trying to remember: immunological B cell memory to malaria

Lars Hviid, Lea Barfod, Freya JI Fowkes

Journal article  |  2015  |  Trends in Parasitology

Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes

Greta E Weiss, Paul R Gilson, Tana Taechalertpaisarn, Wai-Hong Tham, Nienke WM de Jong, Katherine L Harvey, Freya JI Fowkes, Paul N Barlow, Julian C Rayner, Gavin J Wright, Alan F Cowman, Brendan S Crabb

Journal article  |  2015  |  PLOS Pathogens

Acquisition of Antibodies against Plasmodium falciparum Merozoites and Malaria Immunity in Young Children and the Influence of Age, Force of Infection, and Magnitude of Response

Danielle I Stanisic, Freya JI Fowkes, Melanie Koinari, Sarah Javati, Enmoore Lin, Benson Kiniboro, Jack S Richards, Leanne J Robinson, Louis Schofield, James W Kazura, Christopher L King, Peter Zimmerman, Ingrid Felger, Peter M Siba, Ivo Mueller, James G Beeson

Journal article  |  2015  |  Infection and Immunity

Use of Immunodampening To Overcome Diversity in the Malarial Vaccine Candidate Apical Membrane Antigen 1

Karen S Harris, Christopher G Adda, Madhavi Khore, Damien R Drew, Antonina Valentini-Gatt, Freya JI Fowkes, James G Beeson, Sheetij Dutta, Robin F Anders, Michael Foley

Journal article  |  2014  |  Infection and Immunity

Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates

Jo-Anne Chan, Freya JI Fowkes, James G Beeson

Journal article  |  2014  |  Cellular and Molecular Life Sciences

Immunological markers of Plasmodium vivax exposure and immunity: a systematic review and meta-analysis

Julia C Cutts, Rosanna Powell, Paul A Agius, James G Beeson, Julie A Simpson, Freya JI Fowkes

Journal article  |  2014  |  BMC Medicine

Research priorities for the development and implementation of serological tools for malaria surveillance.

Salenna R Elliott, Freya JI Fowkes, Jack S Richards, Linda Reiling, Damien R Drew, James G Beeson

Journal article  |  2014  |  F1000Prime Reports

Surveillance is a key component of control and elimination programs. Malaria surveillance has been typically reliant on case repor..

Implications of the licensure of a partially efficacious malaria vaccine on evaluating second-generation vaccines

Freya JI Fowkes, Julie A Simpson, James G Beeson

Journal article  |  2013  |  BMC Medicine

T-Helper Cell 2-Driven Immunity in Pregnancy as a Determinant of Antiplasmodial Antibody Half-life Through Regulation of Fc-Receptor-Mediated Clearance Reply

Freya JI Fowkes, James G Beeson

Journal article  |  2013  |  J. Infect. Dis.

Erythrocyte-Binding Antigens of Plasmodium falciparum Are Targets of Human Inhibitory Antibodies and Function To Evade Naturally Acquired Immunity

Kristina EM Persson, Freya JI Fowkes, Fiona J McCallum, Nimmo Gicheru, Linda Reiling, Jack S Richards, Danny W Wilson, Sash Lopaticki, Alan F Cowman, Kevin Marsh, James G Beeson

Journal article  |  2013  |  J. Immunol.

Identification and Prioritization of Merozoite Antigens as Targets of Protective Human Immunity to Plasmodium falciparum Malaria for Vaccine and Biomarker Development

Jack S Richards, Thangavelu U Arumugam, Linda Reiling, Julie Healer, Anthony N Hodder, Freya JI Fowkes, Nadia Cross, Christine Langer, Satoru Takeo, Alex D Uboldi, Jennifer K Thompson, Paul R Gilson, Ross L Coppel, Peter M Siba, Christopher L King, Motomi Torii, Chetan E Chitnis, David L Narum, Ivo Mueller, Brendan S Crabb, et al.

Journal article  |  2013  |  Journal of Immunology

Antibody Boosting and Longevity Following Tetanus Immunization During Pregnancy

Freya JI Fowkes, Rose McGready, Simon Johnstone-Robertson, Francois Nosten, James G Beeson

Journal article  |  2013  |  Clinical Infectious Diseases

PfEMP1 as a target of human immunity and a vaccine candidate against malaria

James G Beeson, Jo-Anne Chan, Freya JI Fowkes

Journal article  |  2013  |  Expert Rev. Vaccines

Epistatic Interactions between Apolipoprotein E and Hemoglobin S Genes in Regulation of Malaria Parasitemia

V Rougeron, CM Woods, KE Tiedje, F Bodeau-Livinec, F Migot-Nabias, P Deloron, AJF Luty, FJI Fowkes, KP Day

Journal article  |  2013  |  PLoS ONE

New Insights into Acquisition, Boosting, and Longevity of Immunity to Malaria in Pregnant Women

Freya JI Fowkes, Rose McGready, Nadia J Cross, Mirja Hommel, Julie A Simpson, Salenna R Elliott, Jack S Richards, Kurt Lackovic, Jacher Viladpai-Nguen, David Narum, Takafumi Tsuboi, Robin F Anders, Francois Nosten, James G Beeson

Journal article  |  2012  |  Journal of Infectious Diseases

The Plasmodium falciparum Erythrocyte Invasion Ligand Pfrh4 as a Target of Functional and Protective Human Antibodies against Malaria

Linda Reiling, Jack S Richards, Freya JI Fowkes, Danny W Wilson, Watcharee Chokejindachai, Alyssa E Barry, Wai-Hong Tham, Janine Stubbs, Christine Langer, John Donelson, Pascal Michon, Livingstone Tavul, Brendan S Crabb, Peter M Siba, Alan F Cowman, Ivo Mueller, James G Beeson

Journal article  |  2012  |  PLoS One

Targets of antibodies against Plasmodium falciparum-infected erythrocytes in malaria immunity

Jo-Anne Chan, Katherine B Howell, Linda Reiling, Ricardo Ataide, Claire L Mackintosh, Freya JI Fowkes, Michaela Petter, Joanne M Chesson, Christine Langer, George M Warimwe, Michael F Duffy, Stephen J Rogerson, Peter C Bull, Alan F Cowman, Kevin Marsh, James G Beeson

Journal article  |  2012  |  JOURNAL OF CLINICAL INVESTIGATION

Bacterial Vaginosis (BV) Candidate Bacteria: Associations with BV and Behavioural Practices in Sexually-Experienced and Inexperienced Women

Katherine Fethers, Jimmy Twin, Christopher K Fairley, Freya JI Fowkes, Suzanne M Garland, Glenda Fehler, Anna M Morton, Jane S Hocking, Sepehr N Tabrizi, Catriona S Bradshaw

Journal article  |  2012  |  PLoS One

Individual Variation in Levels of Haptoglobin-Related Protein in Children from Gabon

HJ Imrie, FJI Fowkes, F Migot-Nabias, AJF Luty, P Deloron, SL Hajduk, KP Day

Journal article  |  2012  |  PLoS ONE

Bacterial vaginosis (BV) candidate bacteria: associations with BV and behavioural practices in sexually-experienced and inexperienced women.

KA Fethers, J Twin, CK Fairley, FJ Fowkes, SM Garland, G Fehler, AM Morton, JS Hocking, S Tabrizi, CS Bradshaw

Journal article  |  2012  |  PLoS One

Quantifying the Importance of MSP1-19 as a Target of Growth-Inhibitory and Protective Antibodies against Plasmodium falciparum in Humans

Danny W Wilson, Freya JI Fowkes, Paul R Gilson, Salenna R Elliott, Livingstone Tavul, Pascal Michon, Elija Dabod, Peter M Siba, Ivo Mueller, Brendan S Crabb, James G Beeson

Journal article  |  2011  |  PLoS One

The Stability and Complexity of Antibody Responses to the Major Surface Antigen of Plasmodium falciparum Are Associated with Age in a Malaria Endemic Area

Alyssa E Barry, Angela Trieu, Freya JI Fowkes, Jozelyn Pablo, Mina Kalantari-Dehaghi, Algis Jasinskas, Xiaolin Tan, Matthew A Kayala, Livingstone Tavul, Peter M Siba, Karen P Day, Pierre Baldi, Philip L Felgner, Denise L Doolan

Journal article  |  2011  |  Molecular and Cellular Proteomics

The stability and complexity of antibody responses to the major surface antigen of Plasmodium falciparum are associated with age in a malaria endemic area.

Journal article  |  2011  |  Mol. Cell Proteomics

A Phase 1 Trial of MSP2-C1, a Blood-Stage Malaria Vaccine Containing 2 Isoforms of MSP2 Formulated with Montanide (R) ISA 720

James S McCarthy, Joanne Marjason, Suzanne Elliott, Paul Fahey, Gilles Bang, Elissa Malkin, Eveline Tierney, Hayley Aked-Hurditch, Christopher Adda, Nadia Cross, Jack S Richards, Freya JI Fowkes, Michelle J Boyle, Carole Long, Pierre Druilhe, James G Beeson, Robin F Anders

Journal article  |  2011  |  PLoS ONE

Quantifying Malaria Dynamics Within the Host

Karen P Day, Freya JI Fowkes

Journal article  |  2011  |  SCIENCE

Intermittent Preventive Treatment to Reduce the Burden of Malaria in Children: New Evidence on Integration and Delivery

James G Beeson, Stephen J Rogerson, Ivo Mueller, Jack S Richards, Freya JI Fowkes

Journal article  |  2011  |  PLOS MEDICINE

Evidence That the Erythrocyte Invasion Ligand PfRh2 is a Target of Protective Immunity against Plasmodium falciparum Malaria

Linda Reiling, Jack S Richards, Freya JI Fowkes, Alyssa E Barry, Tony Triglia, Watcharee Chokejindachai, Pascal Michon, Livingstone Tavul, Peter M Siba, Alan F Cowman, Ivo Mueller, James G Beeson

Journal article  |  2010  |  Journal of Immunology

Association between Naturally Acquired Antibodies to Erythrocyte-Binding Antigens of Plasmodium falciparum and Protection from Malaria and High-Density Parasitemia

Jack S Richards, Danielle I Stanisic, Freya JI Fowkes, Livingstone Tavul, Elijah Dabod, Jennifer K Thompson, Sanjeev Kumar, Chetan E Chitnis, David L Narum, Pascal Michon, Peter M Siba, Alan F Cowman, Ivo Mueller, James G Beeson

Journal article  |  2010  |  Clinical Infectious Diseases

Antibodies to Chondroitin Sulfate A- Binding Infected Erythrocytes: Dynamics and Protection during Pregnancy in Women Receiving Intermittent Preventive Treatment

Elizabeth H Aitken, Bernard Mbewe, Mari Luntamo, Ken Maleta, Teija Kulmala, Marc-James Friso, Freya JI Fowkes, James G Beeson, Per Ashorn, Stephen J Rogerson

Journal article  |  2010  |  Journal of Infectious Diseases

Evaluation of the Antigenic Diversity of Placenta-Binding Plasmodium falciparum Variants and the Antibody Repertoire among Pregnant Women

Mirja Hommel, Salenna R Elliott, Viju Soma, Greg Kelly, Freya JI Fowkes, Joanne M Chesson, Michael F Duffy, Joseph Bockhorst, Marion Avril, Ivo Mueller, Andrew Raiko, Danielle I Stanisic, Stephen J Rogerson, Joseph D Smith, James G Beeson

Journal article  |  2010  |  INFECTION AND IMMUNITY

The Relationship between Anti-merozoite Antibodies and Incidence of Plasmodium falciparum Malaria: A Systematic Review and Meta-analysis

Freya JI Fowkes, Jack S Richards, Julie A Simpson, James G Beeson

Journal article  |  2010  |  PLoS Medicine

The acute phase response in children with mild and severe malaria in Papua New Guinea

Angela O'Donnell, Freya JI Fowkes, Stephen J Allen, Heather Imrie, Michael P Alpers, David J Weatherall, Karen P Day

Journal article  |  2009  |  Trans. R. Soc. Trop. Med. Hyg.

Scottish smoke-free legislation and trends in smoking cessation.

Freya JI Fowkes, Marlene CW Stewart, F Gerald R Fowkes, Amanda Amos, Jackie F Price

Journal article  |  2008  |  Addiction

AIM: To investigate trends in smoking cessation before and after the introduction of Scottish smoke-free legislation and to assess..

Acquisition of Growth-Inhibitory Antibodies against Blood-Stage Plasmodium falciparum

Fiona J McCallum, Kristina EM Persson, Cleopatra K Mugyenyi, Freya JI Fowkes, Julie A Simpson, Jack S Richards, Thomas N Williams, Kevin Marsh, James G Beeson

Journal article  |  2008  |  PLoS One

Alpha -thalassaemia and malaria in Melanesia: epidemiological perspectives.

Freya JI Fowkes, Karen P Day

Journal article  |  2008  |  P N G Med J

In 1948 Haldane first proposed that the high frequencies of thalassaemias in malaria-endemic regions were due to natural selection..

Increased microerythrocyte count in homozygous alpha( )- thalassaemia contributes to protection against severe malarial anaemia

Freya JI Fowkes, Stephen J Allen, Angela Allen, Michael P Alpers, David J Weatherall, Karen P Day

Journal article  |  2008  |  PLoS Med.

Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea

Freya JI Fowkes, Pascal Michon, Lynn Pilling, Ruth M Ripley, Livingstone Tavul, Heather J Imrie, Caira M Woods, Charles S Mgone, Adrian JF Luty, Karen P Day

Journal article  |  2008  |  MALARIA JOURNAL