Freya Fowkes

Evaluation of the effectiveness of topical repellent distributed by village health volunteer networks against Plasmodium spp. infection in Myanmar: A stepped-wedge cluster randomised trial

Paul A Agius, Julia C Cutts, Win Han Oo, Aung Thi, Katherine O'Flaherty, Kyaw Zayar Aung, Htin Kyaw Thu, Poe Poe Aung, Myat Mon Thein, Nyi Nyi Zaw, Wai Yan Min Htay, Aung Paing Soe, Zahra Razook, Alyssa E Barry, Win Htike, Angela Devine, Julie A Simpson, Brendan S Crabb, James G Beeson, Naanki Pasricha, et al.

Journal article  |  2020  |  PLoS Medicine

BACKGROUND: The World Health Organization has yet to endorse deployment of topical repellents for malaria prevention as part of pu..

Multi-functional antibodies are induced by the RTS,S malaria vaccine and associated with protection in a phase I/IIa trial.

Liriye Kurtovic, Tanmaya Atre, Gaoqian Feng, Bruce D Wines, Jo-Anne Chan, Michelle J Boyle, Damien R Drew, P Mark Hogarth, Freya JI Fowkes, Elke S Bergmann-Leitner, James G Beeson

Journal article  |  2020  |  The Journal of Infectious Diseases

BACKGROUND: RTS,S is the leading malaria vaccine candidate, but only confers partial efficacy against malaria in children. RTS,S i..

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3 alpha and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M

Damian A Oyong, Danny W Wilson, Bridget E Barber, Timothy William, Jianlin Jiang, Mary R Galinski, Freya JI Fowkes, Matthew J Grigg, James G Beeson, Nicholas M Anstey, Michelle J Boyle

Journal article  |  2019  |  The Journal of Infectious Diseases

BACKGROUND: Complement-fixing antibodies are important mediators of protection against Plasmodium falciparum malaria. However, com..

Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives

Katherine O'Flaherty, Ricardo Ataide, Sophie G Zaloumis, Elizabeth A Ashley, Rosanna Powell, Gaoqian Feng, Linda Reiling, Arjen M Dondorp, Nicholas P Day, Mehul Dhorda, Rick M Fairhurst, Pharath Lim, Chanaki Amaratunga, Sasithon Pukrittayakamee, Tinh Hien Tran, Ye Htut, Mayfong Mayxay, M Abul Faiz, James G Beeson, Francois Nosten, et al.

Journal article  |  2019  |  Journal of Infectious Diseases

BACKGROUND: Antibodies to the blood-stages of malaria enhance parasite-clearance and antimalarial efficacy. The antibody subclass ..

IgM in human immunity to Plasmodium falciparum malaria

MJ Boyle, JA Chan, I Handayuni, L Reiling, G Feng, A Hilton, L Kurtovic, D Oyong, KA Piera, BE Barber, T William, DP Eisen, G Minigo, C Langer, DR Drew, F de Labastida Rivera, FH Amante, TN Williams, S Kinyanjui, K Marsh, et al.

Journal article  |  2019  |  Science Advances

Understanding the interactions between iron supplementation, infectious disease and adverse birth outcomes is essential to guide public health recommendations

Freya JI Fowkes, Eliza Davidson, Paul A Agius, James G Beeson

Journal article  |  2019  |  BMC Medicine

UNINTENDED PREGNANCY AND FAMILY PLANNING USE AMONG ANTENATAL ATTENDEES IN EAST NEW BRITAIN, PAPUA NEW GUINEA

Elizabeth Peach, Chris Morgan, Michelle Scoullar, Freya Fowkes, Elissa Kennedy, Stanley Luchters, Andrew Vallely, Lisa Vallely, Angela Kelly, Leanne Robinson, Brendan Crabb, Peter Siba, William Pomat, JG Beeson

Conference Proceedings  |  2019  |  INTERNAL MEDICINE JOURNAL

Antibody Targets on the Surface of Plasmodium falciparum-Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children

Jo-Anne Chan, Michelle J Boyle, Kerryn A Moore, Linda Reiling, Zaw Lin, Wina Hasang, Marion Avril, Laurens Manning, Ivo Mueller, Moses Laman, Timothy Davis, Joseph D Smith, Stephen J Rogerson, Julie A Simpson, Freya JI Fowkes, James G Beeson

Journal article  |  2019  |  The Journal of Infectious Diseases

Induction and decay of functional complement-fixing antibodies by the RTS,S malariavaccine in children, and a negative impact of malaria exposure

Liriye Kurtovic, Paul A Agius, Gaoqian Feng, Damien R Drew, Itziar Ubillos, Jahit Sacarlal, John J Aponte, Freya JI Fowkes, Carlota Dobano, James G Beeson

Journal article  |  2019  |  BMC Medicine

Targets of complement-fixing antibodies in protective immunity against malaria in children

Linda Reiling, Michelle J Boyle, Michael T White, Danny W Wilson, Gaoqian Feng, Rupert Weaver, D Herbert Opi, Kristina EM Persson, Jack S Richards, Peter M Siba, Freya JI Fowkes, Eizo Takashima, Takafumi Tsuboi, Ivo Mueller, James G Beeson

Journal article  |  2019  |  Nature Communications