Tu Nguyen

Heritable methylation marks associated with prostate cancer risk.

James G Dowty, Chenglong Yu, Mahnaz Hosseinpour, Jihoon Eric Joo, Ee Ming Wong, Tu Nguyen-Dumont, Joseph Rosenbluh, Graham G Giles, Roger L Milne, Robert J MacInnis, Pierre-Antoine Dugué, Melissa C Southey

Journal article  |  2023  |  Fam Cancer

DNA methylation marks that are inherited from parents to offspring are known to play a role in cancer risk and could explain part ..

Clonal hematopoiesis and risk of prostate cancer in large samples of European ancestry men.

Anqi Wang, Yili Xu, Yao Yu, Kevin T Nead, TaeBeom Kim, Keren Xu, Tokhir Dadaev, Ed Saunders, Xin Sheng, Peggy Wan, Loreall Pooler, Lucy Y Xia, Stephen Chanock, Sonja I Berndt, Susan M Gapstur, Victoria Stevens, Demetrius Albanes, Stephanie J Weinstein, Vincent Gnanapragasam, Graham G Giles, et al.

Journal article  |  2023  |  Hum Mol Genet

Little is known regarding the potential relationship between clonal hematopoiesis (CH) of indeterminate potential (CHIP), which is..

Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers.

Christopher Hakkaart, John F Pearson, Louise Marquart, Joe Dennis, George AR Wiggins, Daniel R Barnes, Bridget A Robinson, Peter D Mace, Kristiina Aittomäki, Irene L Andrulis, Banu K Arun, Jacopo Azzollini, Judith Balmaña, Rosa B Barkardottir, Sami Belhadj, Lieke Berger, Marinus J Blok, Susanne E Boonen, Julika Borde, Angela R Bradbury, et al.

Journal article  |  2022  |  Commun Biol

The contribution of germline copy number variants (CNVs) to risk of developing cancer in individuals with pathogenic BRCA1 or BRCA..

Segregation analysis of 17,425 population-based breast cancer families: Evidence for genetic susceptibility and risk prediction

Shuai Li, Robert J MacInnis, Andrew Lee, Tu Nguyen-Dumont, Leila Dorling, Sara Carvalho, Gillian S Dite, Mitul Shah, Craig Luccarini, Qin Wang, Roger L Milne, Mark A Jenkins, Graham G Giles, Alison M Dunning, Paul DP Pharoah, Melissa C Southey, Douglas F Easton, John L Hopper, Antonis C Antoniou

Journal article  |  2022  |  AMERICAN JOURNAL OF HUMAN GENETICS

Rare pathogenic variants in known breast cancer-susceptibility genes and known common susceptibility variants do not fully explain..

Abstract 688: Multi-stage exome sequencing study of 17,546 aggressive and non-aggressive prostate cancer cases

Burcu F Darst, Ed Saunders, Tokhir Dadaev, Xin Sheng, Peggy Wan, Loreall Pooler, Lucy Y Xia, Stephen Chanock, Sonja I Berndt, Susan M Gapstur, Victoria Stevens, Demetrius Albanes, Stephanie J Weinstein, Vincent Gnanapragasam, Graham G Giles, Tu Nguyen-Dumont, Roger L Milne, Mark M Pomerantz, Julie A Schmidt, Ruth C Travis, et al.

Journal article  |  2022  |  Cancer Research

Abstract Rare pathogenic variants in DNA repair genes have been found to influence risk of aggressive prostate canc..

Abstract 532: Circulating tumor DNA and outcomes with lutetium-PSMA in advanced prostate cancer: Preliminary results from an Australian study

Heidi Fettke, Nicole Ng, Christine Hauser, Patricia Bukczynska, Elizabeth Medhurst, Louise Kostos, James Buteau, Jason Steen, Tu Nguyen-Dumont, Michael Hofman, Arun A Azad

Journal article  |  2022  |  Cancer Research

Abstract Recent clinical trials have revealed that Lutetium PSMA-617 (Lu-PSMA, a small molecular inhibitor of prost..

Genetic Aspects of Mammographic Density Measures Associated with Breast Cancer Risk

Shuai Li, Tuong L Nguyen, Nguyen-Dumont Tu, James G Dowty, Gillian S Dite, Zhoufeng Ye, Ho N Trinh, Christopher F Evans, Maxine Tan, Joohon Sung, Mark A Jenkins, Graham G Giles, John L Hopper, Melissa C Southey

Journal article  |  2022  |  CANCERS

Cumulus, Altocumulus, and Cirrocumulus are measures of mammographic density defined at increasing pixel brightness thresholds, whi..

Genome-wide and transcriptome-wide association studies of mammographic density phenotypes reveal novel loci

Hongjie Chen, Shaoqi Fan, Jennifer Stone, Deborah J Thompson, Julie Douglas, Shuai Li, Christopher Scott, Manjeet K Bolla, Qin Wang, Joe Dennis, Kyriaki Michailidou, Christopher Li, Ulrike Peters, John L Hopper, Melissa C Southey, Tu Nguyen-Dumont, Tuong L Nguyen, Peter A Fasching, Annika Behrens, Gemma Cadby, et al.

Journal article  |  2022  |  BREAST CANCER RESEARCH

BACKGROUND: Mammographic density (MD) phenotypes, including percent density (PMD), area of dense tissue (DA), and area of non-dens..

Population DNA screening for medically actionable disease risk in adults.

Paul A Lacaze, Jane Tiller, Ingrid Winship, undefined DNA Screen Investigator Group

Journal article  |  2022  |  Med J Aust

First international workshop of the ATM and cancer risk group (4-5 December 2019).

Fabienne Lesueur, Douglas F Easton, Anne-Laure Renault, Sean V Tavtigian, Jonine L Bernstein, Zsofia Kote-Jarai, Rosalind A Eeles, Dijana Plaseska-Karanfia, Lidia Feliubadaló, undefined Spanish ATM working group, Banu Arun, Natalie Herold, Beatrix Versmold, Rita Katharina Schmutzler, undefined GC-HBOC, Tú Nguyen-Dumont, Melissa C Southey, Leila Dorling, Alison M Dunning, Paola Ghiorzo, et al.

Journal article  |  2022  |  Fam Cancer

The first International Workshop of the ATM and Cancer Risk group focusing on the role of Ataxia-Telangiectasia Mutated (ATM) gene..