Maria Bandala Sanchez

Type 1 diabetes in pregnancy is associated with distinct changes in the composition and function of the gut microbiome

Alexandra J Roth-Schulze, Megan AS Penno, Katrina M Ngui, Helena Oakey, Esther Bandala-Sanchez, Alannah D Smith, Theo R Allnutt, Rebecca L Thomson, Peter J Vuillermin, Maria E Craig, William D Rawlinson, Elizabeth A Davis, Mark Harris, Georgia Soldatos, Peter G Colman, John M Wentworth, Aveni Haynes, Simon C Barry, Richard O Sinnott, Grant Morahan, et al.

Journal article  |  2021  |  MICROBIOME

BACKGROUND: The gut microbiome changes in response to a range of environmental conditions, life events and disease states. Pregnan..

Sialoglycan recognition is a common connection linking acidosis, zinc, and HMGB1 in sepsis

Shoib S Siddiqui, Chirag Dhar, Venkatasubramaniam Sundaramurthy, Aniruddha Sasmal, Hai Yu, Esther Bandala-Sanchez, Miaomiao Li, Xiaoxiao Zhang, Xi Chen, Leonard C Harrison, Ding Xu, Ajit Varki

Journal article  |  2021  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Blood pH is tightly maintained between 7.35 and 7.45, and acidosis (pH <7.3) indicates poor prognosis in sepsis, wherein lactic ac..

Multi-level remodelling of chromatin underlying activation of human T cells

Naiara G Bediaga, Hannah D Coughlan, Timothy M Johanson, Alexandra L Garnham, Gaetano Naselli, Jan Schroeder, Liam G Fearnley, Esther Bandala-Sanchez, Rhys S Allan, Gordon K Smyth, Leonard C Harrison

Journal article  |  2021  |  SCIENTIFIC REPORTS

Remodelling of chromatin architecture is known to regulate gene expression and has been well characterized in cell lineage develop..

The association between intravitreal ranibizumab therapy and serum cytokine concentrations in patients with diabetic macular edema

Sivashanth Gnanasekaran, Esther Bandala-Sanchez, Maria Kolic, Leonid Churilov, Sophie L Rogers, Annie K McAuley, Sukhpal S Sandhu, Salmaan Qureshi, Lyndell L Lim, Sanjeewa S Wickremasinghe

Journal article  |  2020  |  MOLECULAR VISION

Aim: To investigate the association between intravitreal ranibizumab therapy and serum cytokine concentrations in patients with di..

Siglec-10 expression is up-regulated in activated human CD4( ) T cells

E Bandala-Sanchez, NG Bediaga, G Naselli, AM Neale, LC Harrison

Journal article  |  2020  |  HUMAN IMMUNOLOGY

Most sialic acid-binding immunoglobulin-like lectins (Siglecs) suppress immune cell function but are expressed at low levels on hu..

Specific Sialoforms Required for the Immune Suppressive Activity of Human Soluble CD52

Abdulrahman M Shathili, Esther Bandala-Sanchez, Alan John, Ethan D Goddard-Borger, Morten Thaysen-Andersen, Arun V Everest-Dass, Timothy E Adams, Leonard C Harrison, Nicolle H Packer

Journal article  |  2019  |  FRONTIERS IN IMMUNOLOGY

Human CD52 is a small glycopeptide (12 amino acid residues) with one N-linked glycosylation site at asparagine 3 (Asn3) and severa..

RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development

Holly Anderton, Esther Bandala-Sanchez, Daniel S Simpson, James A Rickard, Ashley P Ng, Ladina Di Rago, Cathrine Hall, James E Vince, John Silke, Gianmaria Liccardi, Rebecca Feltham

Journal article  |  2019  |  CELL DEATH AND DIFFERENTIATION

RIPK1 is an essential downstream component of many pattern recognition and death receptors. RIPK1 can promote the activation of ca..

Correction for Bandala-Sanchez et al., CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function.

Journal article  |  2019  |  Proc Natl Acad Sci U S A

IMMUNOLOGY AND INFLAMMATION Correction for “CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor ..

The Influence of Intravitreal Ranibizumab on Inflammation-associated Cytokine Concentrations in Eyes With Diabetic Macular Edema

Shueh Wen Lim, Esther Bandala-Sanchez, Maria Kolic, Sophie L Rogers, Annie K McAuley, Lyndell L Lim, Sanjeewa S Wickremasinghe

Journal article  |  2018  |  INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

Purpose: To evaluate the effect of intravitreal ranibizumab injections on aqueous concentrations of angiogenic or inflammatory cyt..

Minimal variation of the plasma lipidome after delayed processing of neonatal cord blood

John M Wentworth, Naiara G Bediaga, Megan AS Penno, Esther Bandala-Sanchez, Komal N Kanojia, Konstantinos A Kouremenos, Jennifer J Couper, Leonard C Harrison

Journal article  |  2018  |  METABOLOMICS

BACKGROUND: Cord blood lipids are potential disease biomarkers. We aimed to determine if their concentrations were affected by del..