Mark Dowling

Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny

Mark R Dowling, Andrey Kan, Susanne Heinzel, Julia M Marchingo, Philip D Hodgkin, Edwin D Hawkins

Journal article  |  2018  |  Frontiers in Immunology

Neurologic complications after allogeneic hematopoietic stem cell transplantation: risk factors and impact

MR Dowling, S Li, BR Dey, SL McAfee, HR Hock, TR Spitzer, Y-B Chen, KK Ballen

Journal article  |  2018  |  Bone Marrow Transplantation

Regulation of platelet lifespan in the presence and absence of thrombopoietin signaling

M Lebois, MR Dowling, P Gangatirkar, PD Hodgkin, BT Kile, WS Alexander, EC Josefsson

Journal article  |  2016  |  JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Stochastic Measurement Models for Quantifying Lymphocyte Responses Using Flow Cytometry

Andrey Kan, Damian Pavlyshyn, John F Markham, Mark R Dowling, Susanne Heinzel, Jie HS Zhou, Julia M Marchingo, Philip D Hodgkin

Journal article  |  2016  |  PLOS ONE

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

Julia M Marchingo, Andrey Kan, Robyn M Sutherland, Ken R Duffy, Cameron J Wellard, Gabrielle T Belz, Andrew M Lew, Mark R Dowling, Susanne Heinzel, Philip D Hodgkin

Journal article  |  2014  |  Science

Why the immune system takes its chances with randomness

Philip D Hodgkin, Mark R Dowling, Ken R Duffy

Journal article  |  2014  |  Nature Reviews Immunology

Stretched cell cycle model for proliferating lymphocytes

Mark R Dowling, Andrey Kan, Susanne Heinzel, Jie HS Zhou, Julia M Marchingo, Cameron J Wellard, John F Markham, Philip D Hodgkin

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Labour-Efficient In Vitro Lymphocyte Population Tracking and Fate Prediction Using Automation and Manual Review

Rajib Chakravorty, David Rawlinson, Alan Zhang, John Markham, Mark R Dowling, Cameron Wellard, Jie HS Zhou, Philip D Hodgkin

Journal article  |  2014  |  PLoS One

Quantal and graded stimulation of B lymphocytes as alternative strategies for regulating adaptive immune responses

ED Hawkins, ML Turner, CJ Wellard, JHS Zhou, MR Dowling, PD Hodgkin

Journal article  |  2013  |  Nature Communications

The Regulation of Platelet Life Span

EC Josefsson, MR Dowling, M Lebois, BT Kile

Book Chapter  |  2013

A Model for Studying the Hemostatic Consumption or Destruction of Platelets

Mark R Dowling, Emma C Josefsson, Katya J Henley, Benjamin T Kile, Philip D Hodgkin

Journal article  |  2013  |  PLoS One

Activation-Induced B Cell Fates Are Selected by Intracellular Stochastic Competition

Ken R Duffy, Cameron J Wellard, John F Markham, Jie HS Zhou, Ross Holmberg, Edwin D Hawkins, Jhagvaral Hasbold, Mark R Dowling, Philip D Hodgkin

Journal article  |  2012  |  Science

Platelet Life Span and Apoptosis

Emma C Josefsson, Michael J White, Mark R Dowling, Benjamin T Kile

Journal article  |  2012  |  Methods in Molecular Biology

Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets

Emma C Josefsson, Chloe James, Katya J Henley, Marlyse A Debrincat, Kelly L Rogers, Mark R Dowling, Michael J White, Elizabeth A Kruse, Rachael M Lane, Sarah Ellis, Paquita Nurden, Kylie D Mason, Lorraine A O'Reilly, Andrew W Roberts, Donald Metcalf, David CS Huang, Benjamin T Kile

Journal article  |  2011  |  Journal of Experimental Medicine

Platelet senescence is regulated by an internal timer, not damage inflicted by hits

Mark R Dowling, Emma C Josefsson, Katya J Henley, Philip D Hodgkin, Benjamin T Kile

Journal article  |  2010  |  Blood