Mark Dowling

Germline heterozygous mutations in Nxf1 perturb RNA metabolism and trigger thrombocytopenia and lymphopenia in mice

Stephane Chappaz, Charity W Law, Mark R Dowling, Kirstyn T Carey, Rachael M Lane, Linh H Ngo, Vihandha O Wickramasinghe, Gordon K Smyth, Matthew E Ritchie, Benjamin T Kile

Journal article  |  2020  |  Blood Advances

In eukaryotic cells, messenger RNA (mRNA) molecules are exported from the nucleus to the cytoplasm, where they are translated. The..

Neurological Complications after Allogeneic Transplantation - Can We Do Better?

Mark R Dowling, Karen K Ballen

Journal article  |  2019  |  Acta Haematologica

Regulatory T Cells Suppress Effector T Cell Proliferation by Limiting Division Destiny

Mark R Dowling, Andrey Kan, Susanne Heinzel, Julia M Marchingo, Philip D Hodgkin, Edwin D Hawkins

Journal article  |  2018  |  Frontiers in Immunology

Neurologic complications after allogeneic hematopoietic stem cell transplantation: risk factors and impact

MR Dowling, S Li, BR Dey, SL McAfee, HR Hock, TR Spitzer, Y-B Chen, KK Ballen

Journal article  |  2018  |  Bone Marrow Transplantation

Regulation of platelet lifespan in the presence and absence of thrombopoietin signaling

M Lebois, MR Dowling, P Gangatirkar, PD Hodgkin, BT Kile, WS Alexander, EC Josefsson

Journal article  |  2016  |  JOURNAL OF THROMBOSIS AND HAEMOSTASIS

Stochastic Measurement Models for Quantifying Lymphocyte Responses Using Flow Cytometry

Andrey Kan, Damian Pavlyshyn, John F Markham, Mark R Dowling, Susanne Heinzel, Jie HS Zhou, Julia M Marchingo, Philip D Hodgkin

Journal article  |  2016  |  PLOS ONE

Antigen affinity, costimulation, and cytokine inputs sum linearly to amplify T cell expansion

Julia M Marchingo, Andrey Kan, Robyn M Sutherland, Ken R Duffy, Cameron J Wellard, Gabrielle T Belz, Andrew M Lew, Mark R Dowling, Susanne Heinzel, Philip D Hodgkin

Journal article  |  2014  |  Science

Why the immune system takes its chances with randomness

Philip D Hodgkin, Mark R Dowling, Ken R Duffy

Journal article  |  2014  |  Nature Reviews Immunology

Stretched cell cycle model for proliferating lymphocytes

Mark R Dowling, Andrey Kan, Susanne Heinzel, Jie HS Zhou, Julia M Marchingo, Cameron J Wellard, John F Markham, Philip D Hodgkin

Journal article  |  2014  |  Proceedings of the National Academy of Sciences of the United States of America

Labour-Efficient In Vitro Lymphocyte Population Tracking and Fate Prediction Using Automation and Manual Review

Rajib Chakravorty, David Rawlinson, Alan Zhang, John Markham, Mark R Dowling, Cameron Wellard, Jie HS Zhou, Philip D Hodgkin

Journal article  |  2014  |  PLoS One