Melinda Hardy

Characterisation of clinical and immune reactivity to barley and rye ingestion in children with coeliac disease

Melinda Y Hardy, Amy K Russell, Catherine Pizzey, Claerwen M Jones, Katherine A Watson, Nicole L La Gruta, Donald J Cameron, Jason A Tye-Din

Journal article  |  2020  |  Gut

OBJECTIVE: Barley and rye are major components of the Western diet, and historic feeding studies indicate that they cause clinical..

Circulating gluten-specific, but not CMV-specific, CD39( ) regulatory T cells have an oligoclonal TCR repertoire

Laura Cook, C Mee Ling Munier, Nabila Seddiki, Melinda Y Hardy, Robert P Anderson, John Zaunders, Jason A Tye-Din, Anthony D Kelleher, David van Bockel

Journal article  |  2020  |  Clinical and Translational Immunology

Objectives: Understanding the T cell receptor (TCR) repertoire of regulatory CD4+ T-cell (Treg) populations is important for strat..

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease

Jan Petersen, Laura Ciacchi, Mai T Tran, Khai Lee Loh, Yvonne Kooy-Winkelaar, Nathan P Croft, Melinda Y Hardy, Zhenjun Chen, James McCluskey, Robert P Anderson, Anthony W Purcell, Jason A Tye-Din, Frits Koning, Hugh H Reid, Jamie Rossjohn

Journal article  |  2019  |  Nature Structural & Molecular Biology

The human leukocyte antigen (HLA) locus is strongly associated with T cell-mediated autoimmune disorders. HLA-DQ2.5-mediated celia..

Preparation and Characterization of Avenin-Enriched Oat Protein by Chill Precipitation for Feeding Trials in Celiac Disease.

Greg Tanner, Angéla Juhász, Christakis George Florides, Mitchell Nye-Wood, Frank Békés, Michelle L Colgrave, Amy K Russell, Melinda Y Hardy, Jason A Tye-Din

Journal article  |  2019  |  Frontiers in Nutrition

The safety of oats for people with celiac disease remains unresolved. While oats have attractive nutritional properties that can i..

T cells in coeliac disease: a rational target for diagnosis and therapy

Melinda Y Hardy, Jason A Tye-Din

Journal article  |  2018  |  Nature Reviews Gastroenterology & Hepatology

Resolving incomplete single nucleotide polymorphism tagging of HLA-DQ2.2 for coeliac disease genotyping using digital droplet PCR

MY Hardy, N Ontiveros, MD Varney, JA Tye-Din

Journal article  |  2018  |  HLA

Circulating gluten-specific FOXP3( )CD39( ) regulatory T cells have impaired suppressive function in patients with celiac disease

Laura Cook, C Mee Ling Munier, Nabila Seddiki, David van Bockel, Noe Ontiveros, Melinda Y Hardy, Jana K Gillies, Megan K Levings, Hugh H Reid, Jan Petersen, Jamie Rossjohn, Robert P Anderson, John J Zaunders, Jason A Tye-Din, Anthony D Kelleher

Journal article  |  2017  |  Journal of Allergy and Clinical Immunology

Coeliac disease: a unique model for investigating broken tolerance in autoimmunity

Melinda Y Hardy, Jason A Tye-Din

Journal article  |  2016  |  Clinical and Translational Immunology

Age-Related Immunoreactivity to Gluten Peptides in Celiac Disease Reply

Melinda Y Hardy, Robert P Anderson, Jason A Tye-Din

Journal article  |  2016  |  Gastroenterology

Consistency in Polyclonal T-cell Responses to Gluten Between Children and Adults With Celiac Disease

Melinda Y Hardy, Adam Girardin, Catherine Pizzey, Donald J Cameron, Katherine A Watson, Stefania Picascia, Renata Auricchio, Luigi Greco, Carmen Gianfrani, Nicole L La Gruta, Robert P Anderson, Jason A Tye-Din

Journal article  |  2015  |  Gastroenterology