Adeline Robin

Biophysical Characterization of Pro-apoptotic BimBH3 Peptides Reveals an Unexpected Capacity for Self-Association.

Tufa E Assafa, Sukhendu Nandi, Dariusz Śmiłowicz, Laura Galazzo, Markus Teucher, Christina Elsner, Stefanie Pütz, Stephanie Bleicken, Adeline Y Robin, Dana Westphal, Isabel Uson, Raphael Stoll, Peter E Czabotar, Nils Metzler-Nolte, Enrica Bordignon

Journal article  |  2020  |  Structure

Bcl-2 proteins orchestrate the mitochondrial pathway of apoptosis, pivotal for cell death. Yet, the structural details of the conf..

Tyrosine metabolism: identification of a key residue in the acquisition of prephenate aminotransferase activity by 1β aspartate aminotransferase.

Cecile Giustini, Matthieu Graindorge, David Cobessi, Serge Crouzy, Adeline Robin, Gilles Curien, Michel Matringe

Journal article  |  2019  |  The FEBS Journal

Alternative routes for the post-chorismate branch of the biosynthetic pathway leading to tyrosine exist, the 4-hydroxyphenylpyruva..

BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association

Michael A Dengler, Adeline Y Robin, Leonie Gibson, Mark X Li, Jarrod J Sandow, Sweta Iyer, Andrew Webb, Dana Westphal, Grant Dewson, Jerry M Adams

Journal article  |  2019  |  Cell Reports

Ensemble Properties of Bax Determine Its Function

Adeline Y Robin, Sweta Iyer, Richard W Birkinshaw, Jarrod Sandow, Ahmad Wardak, Cindy S Luo, Melissa Shi, Andrew Webb, Peter E Czabotar, Ruth M Kluck, Peter M Colman

Journal article  |  2018  |  Structure

Conversion of Bim-BH3 from Activator to Inhibitor of Bak through Structure-Based Design

Jason M Brouwer, Ping Lan, Angus D Cowan, Jonathan P Bernardini, Richard W Birkinshaw, Mark F van Delft, Brad E Sleebs, Adeline Y Robin, Ahmad Wardak, Iris K Tan, Boris Reljic, Erinna F Lee, W Douglas Fairlie, Melissa J Call, Brian J Smith, Grant Dewson, Guillaume Lessene, Peter M Colman, Peter E Czabotar

Journal article  |  2017  |  Molecular Cell

Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interaction

AY Robin, K Krishna Kumar, D Westphal, AZ Wardak, GV Thompson, G Dewson, PM Colman, PE Czabotar

Journal article  |  2015  |  Cell Death & Disease

Bak Core and Latch Domains Separate during Activation, and Freed Core Domains Form Symmetric Homodimers

Jason M Brouwer, Dana Westphal, Grant Dewson, Adeline Y Robin, Rachel T Uren, Ray Bartolo, Geoff V Thompson, Peter M Colman, Ruth M Kluck, Peter E Czabotar

Journal article  |  2014  |  Molecular Cell

Bax Crystal Structures Reveal How BH3 Domains Activate Bax and Nucleate Its Oligomerization to Induce Apoptosis

Peter E Czabotar, Dana Westphal, Grant Dewson, Stephen Ma, Colin Hockings, W Douglas Fairlie, Erinna F Lee, Shenggen Yao, Adeline Y Robin, Brian J Smith, David CS Huang, Ruth M Kluck, Jerry M Adams, Peter M Colman

Journal article  |  2013  |  Cell

Silver coordination polymers with isonicotinic acid derived short polyethylene glycol-Synthesis, structures, anion effect and solution behavior

KM Fromm, JL Sagué, AY Robin

Journal article  |  2013  |  Inorganica Chimica Acta

The Dendritic Cell Receptor Clec9A Binds Damaged Cells via Exposed Actin Filaments

Jian-Guo Zhang, Peter E Czabotar, Antonia N Policheni, Irina Caminschi, Soo San Wan, Susie Kitsoulis, Kirsteen M Tullett, Adeline Y Robin, Rajini Brammananth, Mark F van Delft, Jinhua Lu, Lorraine A O'Reilly, Emma C Josefsson, Benjamin T Kile, Wei Jin Chin, Justine D Mintern, Maya A Olshina, Wilson Wong, Jake Baum, Mark D Wright, et al.

Journal article  |  2012  |  IMMUNITY