Andrew Lonsdale

ALLSorts: an RNA-Seq subtype classifier for B-cell acute lymphoblastic leukemia

Breon Schmidt, Lauren M Brown, Georgina L Ryland, Andrew Lonsdale, Hansen J Kosasih, Louise E Ludlow, Ian J Majewski, Piers Blombery, Paul G Ekert, Nadia M Davidson, Alicia Oshlack

Journal article  |  2022  |  BLOOD ADVANCES

B-cell acute lymphoblastic leukemia (B-ALL) is the most common childhood cancer. Subtypes within B-ALL are distinguished by charac..

Effects of Excess Manganese on the Xylem Sap Protein Profile of Tomato (Solanum lycopersicum) as Revealed by Shotgun Proteomic Analysis

Laura Ceballos-Laita, Elain Gutierrez-Carbonell, Daisuke Takahashi, Andrew Lonsdale, Anunciacion Abadia, Monika S Doblin, Antony Bacic, Matsuo Uemura, Javier Abadia, Ana Flor Lopez-Millan

Journal article  |  2020  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Metal toxicity is a common problem in crop species worldwide. Some metals are naturally toxic, whereas others such as manganese (M..

The application of RNA sequencing for the diagnosis and genomic classification of pediatric acute lymphoblastic leukemia

Lauren M Brown, Andrew Lonsdale, Andrea Zhu, Nadia M Davidson, Breon Schmidt, Anthony Hawkins, Elise Wallach, Michelle Martin, Francoise M Mechinaud, Seong Lin Khaw, Ray C Bartolo, Louise EA Ludlow, Jackie Challis, Ian Brooks, Vida Petrovic, Nicola C Venn, Rosemary Sutton, Ian J Majewski, Alicia Oshlack, Paul G Ekert

Journal article  |  2020  |  BLOOD ADVANCES

Acute lymphoblastic leukemia (ALL) is the most common childhood malignancy, and implementation of risk-adapted therapy has been in..

Bionitio: demonstrating and facilitating best practices for bioinformatics command-line software

Peter Georgeson, Anna Syme, Clare Sloggett, Jessica Chung, Harriet Dashnow, Michael Milton, Andrew Lonsdale, David Powell, Torsten Seemann, Bernard Pope

Journal article  |  2019  |  GIGASCIENCE

BACKGROUND: Bioinformatics software tools are often created ad hoc, frequently by people without extensive training in software de..

STRetch: detecting and discovering pathogenic short tandem repeat expansions

Harriet Dashnow, Monkol Lek, Belinda Phipson, Andreas Halman, Simon Sadedin, Andrew Lonsdale, Mark Davis, Phillipa Lamont, Joshua S Clayton, Nigel G Laing, Daniel G MacArthur, Alicia Oshlack

Journal article  |  2018  |  GENOME BIOLOGY

Short tandem repeat (STR) expansions have been identified as the causal DNA mutation in dozens of Mendelian diseases. Most existin..

Ten Simple Rules for a Bioinformatics Journal Club

Andrew Lonsdale, Jocelyn Sietsma Penington, Timothy Rice, Michael Walker, Harriet Dashnow

Journal article  |  2016  |  PLOS COMPUTATIONAL BIOLOGY