Clare Whitehead

Consider pregnancy in COVID-19 therapeutic drug and vaccine trials

Clare L Whitehead, Susan P Walker

Journal article  |  2020  |  The Lancet

Circulating mRNAs are differentially expressed in pregnancies with severe placental insufficiency and at high risk of stillbirth

Natalie J Hannan, Owen Stock, Rebecca Spencer, Clare Whitehead, Anna L David, Katie Groom, Scott Petersen, Amanda Henry, Joanne M Said, Sean Seeho, Stefan C Kane, Lavinia Gordon, Sally Beard, Kantaraja Chindera, Smita Karegodar, Richard Hiscock, Natasha Pritchard, Tu'uhevaha J Kaitu'u-Lino, Susan P Walker, Stephen Tong

Journal article  |  2020  |  BMC Medicine

BACKGROUND: Fetuses affected by placental insufficiency do not receive adequate nutrients and oxygenation, become growth restricte..

Wharton's jelly area and its association with placental morphometry and pathology.

Sarah K Debebe, Lindsay S Cahill, John C Kingdom, Clare L Whitehead, Anjana Ravi Chandran, W Tony Parks, Lena Serghides, Ahmet Baschat, Christopher K Macgowan, John G Sled

Journal article  |  2020  |  Placenta

INTRODUCTION: Wharton's jelly (WJ) is the mucoid connective tissue that surrounds the vessels in the human umbilical cord and prov..

The dispensing of psychotropic medicines to older people before and after they enter residential aged care.

Stephanie L Harrison, Janet K Sluggett, Catherine Lang, Craig Whitehead, Maria Crotty, Megan Corlis, Steven L Wesselingh, Maria C Inacio

Journal article  |  2020  |  Medical Journal of Australia

OBJECTIVE: To examine the prevalence of psychotropic medicine dispensing before and after older people enter residential care. DES..

Beyond Experiential Learning in Project-Based Quality Improvement Education: Questioning Assumptions and Identifying Future Directions.

Joanne Goldman, Ayelet Kuper, G Ross Baker, Beverly Bulmer, Maitreya Coffey, Lianne Jeffs, Christine Shea, Cynthia Whitehead, Kaveh Shojania, Brian Wong

Journal article  |  2020  |  Academic Medicine

PURPOSE: Project-based experiential learning is a defining element of quality improvement (QI) education despite ongoing challenge..

When logics of learning conflict: an analysis of two workplace-based continuing education programs.

Paula Rowland, Victoria Boyd, Dean Lising, Joanne Goldman, Cynthia Whitehead, Stella L Ng

Journal article  |  2020  |  Advances in Health Sciences Education

Educators, practitioners, and policy makers are calling for stronger connections between continuing education (CE) for professiona..

The compatibility principle: on philosophies in the assessment of clinical competence.

Walter Tavares, Ayelet Kuper, Kulamakan Kulasegaram, Cynthia Whitehead

Journal article  |  2019  |  Advances in Health Sciences Education

The array of different philosophical positions underlying contemporary views on competence, assessment strategies and justificatio..

Effect of maternal betamethasone administration on feto-placental vascular resistance in the mouse†.

Lindsay S Cahill, Clare L Whitehead, Sebastian R Hobson, Greg Stortz, John C Kingdom, Ahmet Baschat, Kellie E Murphy, Lena Serghides, Christopher K Macgowan, John G Sled

Journal article  |  2019  |  Biology of Reproduction

Antenatal corticosteroids are often administered to women at risk of preterm birth to accelerate fetal lung development; however, ..

Risk of recurrent shoulder dystocia: are we any closer to prediction?

Shadha Al-Hawash, Clare L Whitehead, Dan Farine

Journal article  |  2019  |  The Journal of Maternal-Fetal & Neonatal Medicine

Objective: To determine the incidence and risk factors for recurrent shoulder dystocia in women. Methods: We searched Medline, Pub..

One Size Does Not Fit All: Balancing Individual and System Needs in Primary Care and Beyond.

Cynthia Whitehead, Elise Paradis

Journal article  |  2019  |  Academic Medicine

In this issue, Dewan and Norcini invite readers to reconsider the basic minimum standards for independent primary care practice. T..

A Reappraisal of Circulating Fetal Cell Noninvasive Prenatal Testing.

Meysam Rezaei, Marnie Winter, Deirdre Zander-Fox, Clare Whitehead, Jan Liebelt, Majid Ebrahimi Warkiani, Tristan Hardy, Benjamin Thierry

Journal article  |  2019  |  Trends in Biotechnology

New tools for higher-resolution fetal genome analysis including microarray and next-generation sequencing have revolutionized pren..

Placental vascular abnormalities in the mouse alter umbilical artery wave reflections.

Lindsay S Cahill, Yu-Qing Zhou, Johnathan Hoggarth, Lisa X Yu, Anum Rahman, Greg Stortz, Clare L Whitehead, Ahmet Baschat, John C Kingdom, Christopher K Macgowan, Lena Serghides, John G Sled

Journal article  |  2019  |  American Journal of Physiology-Heart and Circulatory Physiology

Current methods to detect placental vascular pathologies that monitor Doppler ultrasound changes in umbilical artery (UA) pulsatil..

Are increased fetal movements always reassuring?

Clare L Whitehead, Nicole Cohen, Gerard HA Visser, Dan Farine

Journal article  |  2019  |  The Journal of Maternal-Fetal & Neonatal Medicine

Many studies have reported on the association of reduced fetal movements and stillbirth, but little is known about excessive fetal..

EGFL7 gene expression is regulated by hypoxia in trophoblast and altered in the plasma of patients with early preeclampsia

Clare L Whitehead, Tu'uhevaha J Kaitu'u-Lino, Natalie K Binder, Sally Beard, Natasha De Alwis, Fiona Brownfoot, Stephen Tong, Natalie J Hannan

Journal article  |  2018  |  Pregnancy Hypertension

Severe placental insufficiency, acidemia and imminent stillbirth are associated with changes in circulating levels of mRNA coding NR4A2, RCBTB2 and EMP1

Stephen Tong, Clare Whitehead, Susan Walker, Gordon Lavinia, Jo Said, Katie Groom, Scott Petersen, Sean Seeho, Amanda Henry, Stefan Kane, Natalie Hannan, Owen Stock

Conference Proceedings  |  2018  |  AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Activating Transcription Factor 3 Is Reduced in Preeclamptic Placentas and Negatively Regulates sFlt-1 (Soluble fms-Like Tyrosine Kinase 1), Soluble Endoglin, and Proinflammatory Cytokines in Placenta

Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot, Roxanne Hastie, Ashwini Chand, Ping Cannon, Minh Deo, Laura Tuohey, Clare Whitehead, Natalie J Hannan, Stephen Tong

Journal article  |  2017  |  Hypertension

The circulating microRNA-200 family in whole blood are potential biomarkers for high-grade serous epithelial ovarian cancer

Adam Pendlebury, Natalie J Hannan, Natalie Binder, Sally Beard, Monica Mcgauran, Peter Grant, Stephen Tong, Clare L Whitehead

Journal article  |  2017  |  Biomedical Reports

Variable effect of maternal oral glucose load on circulating cell-free placental mRNAs

Teresa Mary MacDonald, Tu'uhevaha Joy Kaitu'u-Lino, Susan Philippa Walker, Kirsten Margaret Dane, Elizabeth Beatrice Lockie, Stephen Tong, Clare Louise Whitehead, Lisa Hui

Journal article  |  2017  |  The Journal of Maternal-Fetal & Neonatal Medicine

Neonatal outcomes after introduction of a national intrapartum fetal surveillance education program: a retrospective cohort study

LD Brown, M Permezel, JR Holberton, CL Whitehead

Journal article  |  2017  |  The Journal of Maternal-Fetal & Neonatal Medicine

Steroid sulfatase is increased in the placentas and whole blood of women with early-onset preeclampsia

Amy M Gratton, Louie Ye, Fiona C Brownfoot, Natalie J Hannan, Clare Whitehead, Ping Cannon, Minh Deo, Peter J Fuller, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2016  |  Placenta

IFPA meeting 2015 workshop report II: mechanistic role of the placenta in fetal programming; biomarkers of placental function and complications of pregnancy

PH Andraweera, G Bobek, C Bowen, GJ Burton, P Correa Frigerio, A Chaparro, H Dickinson, G Duncombe, J Hyett, SE Illanes, E Johnstone, S Kumar, TK Morgan, J Myers, R Orefice, CT Roberts, CM Salafia, KL Thornburg, CL Whitehead, SA Bainbridge

Journal article  |  2016  |  Placenta

Measuring circulating placental RNAs to non-invasively assess the placental transcriptome and to predict pregnancy complications

Clare L Whitehead, Susan P Walker, Stephen Tong

Journal article  |  2016  |  Prenatal Diagnosis

Identifying late-onset fetal growth restriction by measuring circulating placental RNA in the maternal blood at 28 weeks' gestation

Clare L Whitehead, Helen McNamara, Susan P Walker, Maria Alexiadis, Peter J Fuller, Daniel K Vickers, Natalie J Hannan, Roxanne Hastie, Laura Tuohey, Tu'uhevaha J Kaitu'u-Lino, Stephen Tong

Journal article  |  2016  |  American Journal of Obstetrics and Gynecology

Placental Insufficiency in Fetuses That Slow in Growth but Are Born Appropriate for Gestational Age: A Prospective Longitudinal Study

Nadia Bardien, Clare L Whitehead, Stephen Tong, Antony Ugoni, Susan McDonald, Susan P Walker

Journal article  |  2016  |  PLOS ONE

Heme Oxygenase-1 Is Not Decreased in Preeclamptic Placenta and Does Not Negatively Regulate Placental Soluble fms-Like Tyrosine Kinase-1 or Soluble Endoglin Secretion

Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Kenji Onda, Sally Beard, Roxanne Hastie, Natalie K Binder, Cathy Cluver, Laura Tuohey, Clare Whitehead, Fiona Brownfoot, Manarangi De Silva, Natalie J Hannan

Journal article  |  2015  |  HYPERTENSION

Maternal vitamin D supplementation during pregnancy prevents vitamin D deficiency in the newborn: an open-label randomized controlled trial

CP Rodda, JE Benson, AJ Vincent, CL Whitehead, A Polykov, B Vollenhoven

Journal article  |  2015  |  Clinical Endocrinology

Chorioamnionitis Occurring in Women With Preterm Rupture of the Fetal Membranes Is Associated With a Dynamic Increase in mRNAs Coding Cytokines in the Maternal Circulation

Owen Stock, Lavinia Gordon, Jada Kapoor, Susan P Walker, Clare Whitehead, Tu'uhevaha J Kaitu'u-Lino, Gabrielle Pell, Natalie J Hannan, Stephen Tong

Journal article  |  2015  |  REPRODUCTIVE SCIENCES

Treatment of Early-Onset Preeclampsia With Continuous Positive Airway Pressure

Clare Whitehead, Stephen Tong, Danielle Wilson, Mark Howard, Susan P Walker

Journal article  |  2015  |  Obstetrics & Gynecology

Measuring hypoxia-induced RNA in maternal blood: a new way to identify critically hypoxic fetuses in utero?

Clare L Whitehead, Stephen Tong

Journal article  |  2014  |  Expert Reviews in Molecular Diagnosis

Quantifying circulating hypoxia-induced RNA transcripts in maternal blood to determine in utero fetal hypoxic status

Clare Whitehead, Wan Tinn Teh, Susan P Walker, Cheryl Leung, Sonali Mendis, Luke Larmour, Stephen Tong

Journal article  |  2013  |  BMC Medicine

Circulating MicroRNAs in Maternal Blood as Potential Biomarkers for Fetal Hypoxia In-Utero

Clare L Whitehead, Wan Tinn Teh, Susan P Walker, Cheryl Leung, Luke Larmour, Stephen Tong

Journal article  |  2013  |  PLoS One

Effects of Gefitinib, an Epidermal Growth Factor Receptor Inhibitor, on Human Placental Cell Growth

Ulrika W Nilsson, Terrance G Johns, Tania Wilmann, Tu'uhevaha Kaitu'u-Lino, Clare Whitehead, Eva Dimitriadis, Ellen Menkhorst, Burcu Saglam, Yane Gao, Sameer A Greenall, Andrew W Horne, Stephen Tong

Journal article  |  2013  |  Obstetrics and Gynecology

Quantifying mRNA coding growth genes in the maternal circulation to detect fetal growth restriction

Clare L Whitehead, Susan P Walker, Sonali Mendis, Martha Lappas, Stephen Tong

Journal article  |  2013  |  AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Circulating RNA coding genes regulating apoptosis in maternal blood in severe early onset fetal growth restriction and pre-eclampsia

CL Whitehead, SP Walker, M Lappas, S Tong

Journal article  |  2013  |  Journal of Perinatology

Placental Specific mRNA in the Maternal Circulation Are Globally Dysregulated in Pregnancies Complicated by Fetal Growth Restriction

Clare L Whitehead, Susan P Walker, Louie Ye, Sonali Mendis, Tu'uhevaha J Kaitu'u-Lino, Martha Lappas, Stephen Tong

Journal article  |  2013  |  Journal of Clinical Endocrinology & Metabolism

MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin

Tu'uhevaha J Kaitu'u-Lino, Kirsten R Palmer, Clare L Whitehead, Elizabeth Williams, Martha Lappas, Stephen Tong

Journal article  |  2012  |  American Journal of Pathology

Serum Concentrations of Soluble Flt-1 Are Decreased among Women with a Viable Fetus and No Symptoms of Miscarriage Destined for Pregnancy Loss

Tu'uhevaha J Kaitu'u-Lino, Clare L Whitehead, Gene-Lyn Ngian, Michael Permezel, Stephen Tong

Journal article  |  2012  |  PLOS ONE

Characterization of Symptoms Immediately Preceding Eclampsia

Shamil D Cooray, Sally M Edmonds, Stephen Tong, Sumudu P Samarasekera, Clare L Whitehead

Journal article  |  2011  |  Obstetrics and Gynecology

Measurement of mRNA Transcripts of Very High Placental Expression in Maternal Blood as Biomarkers of Preeclampsia

Premila Paiva, Clare Whitehead, Burcu Saglam, Kirsten Palmer, Stephen Tong

Journal article  |  2011  |  Journal of Clinical Endocrinology & Metabolism

Peroxisome proliferator-activated receptors are altered in pathologies of the human placenta: Gestational diabetes mellitus, intrauterine growth restriction and preeclampsia

SJ Holdsworth-Carson, R Lim, A Mitton, C Whitehead, GE Rice, M Permezel, M Lappas

Journal article  |  2010  |  Placenta