Kirsten Palmer

Challenging the definition of hypertension in pregnancy: a retrospective cohort study.

Maya Reddy, Daniel Lorber Rolnik, Katrina Harris, Wentao Li, Ben Willem Mol, Fabricio Da Silva Costa, Euan M Wallace, Kirsten Palmer

Conference Proceedings  |  2020  |  American Journal of Obstetrics and Gynecology

BACKGROUND: In routine antenatal care, blood pressure is used as a screening tool for preeclampsia and its associated adverse outc..

Acceptability of dietary or nutritional supplementation in pregnancy (ADONS) - Exploring the consumer's perspective on introducing creatine monohydrate as a pregnancy supplement

Deborah L de Guingand, Kirsten R Palmer, Jade E Bilardi, Stacey J Ellery

Journal article  |  2020  |  Midwifery

BACKGROUND: Pre-clinical studies suggest maternal dietary creatine supplementation during pregnancy could protect babies against h..

Changes in the modes of twin birth in Victoria, 1983-2015.

Yizhen Amy Liu, Mary-Ann Davey, Rilka Lee, Kirsten R Palmer, Euan M Wallace

Journal article  |  2020  |  Medical Journal of Australia

OBJECTIVES: To examine changes in the modes of delivery of twins in Victoria over 33 years. DESIGN: Retrospective population-based..

Pregnancy Prolongation After Eculizumab Use in Early-Onset Preeclampsia.

Angela B Lu, Benjamin Lazarus, Daniel L Rolnik, Kirsten R Palmer

Journal article  |  2019  |  Obstetrics & Gynecology

BACKGROUND: Untreated microangiopathic hemolytic anemia in pregnancy is associated with adverse maternal and perinatal outcomes. A..

Evaluation of Cardiac Function in Women With a History of Preeclampsia: A Systematic Review and Meta-Analysis

Maya Reddy, Leah Wright, Daniel Lorber Rolnik, Wentao Li, Ben Willem Mol, Andre La Gerche, Fabricio da SilvaCosta, Euan M Wallace, Kirsten Palmer

Journal article  |  2019  |  Journal of the American Heart Association

Background Women with a history of preeclampsia are at increased risk of cardiovascular morbidity and mortality. However, the unde..

Prolong: a double-blind randomised placebo-controlled trial of broccoli sprout extract in women with early onset preeclampsia. A clinical trial protocol.

Annie G Langston-Cox, Sarah A Marshall, Kirsten R Palmer, Euan M Wallace

Journal article  |  2019  |  BMJ Open

INTRODUCTION: Preeclampsia is a leading cause of maternal and perinatal morbidity and mortality. There is a need for adjuvant, tar..

Stability of placental growth factor, soluble fms-like tyrosine kinase 1, and soluble fms-like tyrosine kinase 1 e15a in human serum and plasma.

Saskia Rowson, Maya Reddy, Daniel L Rolnik, Fabricio Da Silva Costa, Kirsten R Palmer

Journal article  |  2019  |  Placenta

Placental growth factor (PlGF), total soluble fms-like tyrosine-kinase 1 (sFlt-1) and its placental-specific variant, sFlt-1 e15a,..

Protect-me: a parallel-group, triple blinded, placebo-controlled randomised clinical trial protocol assessing antenatal maternal melatonin supplementation for fetal neuroprotection in early-onset fetal growth restriction.

Kirsten R Palmer, Joanne C Mockler, Miranda L Davies-Tuck, Suzanne L Miller, Stacy K Goergen, Michael C Fahey, Peter J Anderson, Katie M Groom, Euan M Wallace

Journal article  |  2019  |  BMJ Open

INTRODUCTION: Fetal growth restriction (FGR) is a serious pregnancy complication, associated with increased rates of perinatal dea..

Comparison of maternal and perinatal outcomes in women with super obesity based on planned mode of delivery.

Anisha Parambi, Miranda Davies-Tuck, Kirsten R Palmer

Journal article  |  2019  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

BACKGROUND: Currently, little evidence exists to guide mode of delivery in pregnant women with super obesity. There is a trend tow..

Inter-twin delivery interval, short-term perinatal outcomes and risk of caesarean for the second twin.

Ronit Cukierman, Sarah Heland, Kirsten Palmer, Peter Neil, Fabricio da Silva Costa, Daniel L Rolnik

Journal article  |  2019  |  Australian and New Zealand Journal of Obstetrics and Gynaecology

OBJECTIVE: To examine the association between inter-twin delivery interval and short-term perinatal outcomes of the second twin af..

Proton Pump Inhibitors and Preeclampsia Risk Among 157 720 Women A Swedish Population Register-Based Cohort Study

Roxanne Hastie, Lina Bergman, Catherin A Cluver, Anna Wikman, Natalie J Hannan, Susan P Walker, Anna-Karin Wikstrom, Stephen Tong, Susanne Hesselman

Journal article  |  2019  |  Hypertension

Current and emerging pharmacotherapy for emergency management of preeclampsia.

Annie G Cox, Sarah A Marshall, Kirsten R Palmer, Euan M Wallace

Journal article  |  2019  |  Expert Opinion on Pharmacotherapy

INTRODUCTION: Preeclampsia is a disease specific to pregnancy characterised by new onset hypertension with maternal organ dysfunct..

Management of intrahepatic cholestasis in pregnancy.

Kirsten R Palmer, Liu Xiaohua, Ben W Mol

Journal article  |  2019  |  The Lancet

Undiagnosed maternal diaphragmatic hernia - a management dilemma.

Maya Reddy, Annie Kroushev, Kirsten Palmer

Journal article  |  2018  |  BMC Pregnancy and Childbirth

BACKGROUND: Maternal diaphragmatic hernias identified during pregnancy are rare and pose significant management challenges with re..

Uterine Artery Doppler in Screening for Preeclampsia and Fetal Growth Restriction.

Marianna Amaral Pedroso, Kirsten Rebecca Palmer, Ryan James Hodges, Fabricio da Silva Costa, Daniel Lorber Rolnik

Journal article  |  2018  |  Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics

OBJECTIVE:  To perform a comprehensive review of the current evidence on the role of uterine artery Doppler, isolated or in combin..

Accurately Predicting the Risk of Serious Maternal Morbidity in Preterm Preeclampsia: Can It Be Done?

Kirsten R Palmer, Stephen Tong

Journal article  |  2018  |  Hypertension

Assessing the Circulating Placental-Specific Anti-angiogenic Protein sFLT-1 e15a in Preeclampsia.

Kirsten Palmer

Book Chapter  |  2018  |  Methods in Molecular Biology

Preeclampsia is a common obstetric complication globally responsible for a significant burden of maternal and perinatal morbidity ..

Resveratrol inhibits release of soluble fms-like tyrosine kinase (sFlt-1) and soluble endoglin and improves vascular dysfunction - implications as a preeclampsia treatment

Natalie J Hannan, Fiona C Brownfoot, Ping Cannon, Minh Deo, Sally Beard, Tuong V Nguyen, Kirsten R Palmer, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2017  |  Scientific Reports

Maternal plasma concentrations of the placental specific sFLT-1 variant, sFLT-1 e15a, in fetal growth restriction and preeclampsia

Kirsten R Palmer, Tu'uhevaha J Kaitu'u-Lino, Ping Cannon, Laura Tuohey, Manarangi S De Silva, Manuel Varas-Godoy, Stephanie Acuna, Jose Galaz, Stephen Tong, Sebastian E Illanes

Journal article  |  2017  |  The Journal of Maternal-Fetal & Neonatal Medicine

Proton Pump Inhibitors Decrease Soluble fms-Like Tyrosine Kinase-1 and Soluble Endoglin Secretion, Decrease Hypertension, and Rescue Endothelial Dysfunction

Kenji Onda, Stephen Tong, Sally Beard, Natalie Binder, Masanaga Muto, Sevvandi N Senadheera, Laura Parry, Mark Dilworth, Lewis Renshall, Fiona Brownfoot, Roxanne Hastie, Laura Tuohey, Kirsten Palmer, Toshihiko Hirano, Masahito Ikawa, Tu'uhevaha Kaitu'u-Lino, Natalie J Hannan

Journal article  |  2017  |  Hypertension

Placental-specific sFLT-1: role in pre-eclamptic pathophysiology and its translational possibilities for clinical prediction and diagnosis

KR Palmer, S Tong, TJ Kaitu'u-Lino

Journal article  |  2017  |  MOLECULAR HUMAN REPRODUCTION

Nuclear factor of activated T-cells (NFAT) regulates soluble fms-like tyrosine kinase-1 secretion (sFlt-1) from human placenta

Louie Ye, Amy Gratton, Natalie J Hannan, Ping Cannon, Minh Deo, Kirsten R Palmer, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino, Fiona C Brownfoot

Journal article  |  2016  |  PLACENTA

Jumonji Domain Containing Protein 6 Is Decreased in Human Preeclamptic Placentas and Regulates sFLT-1 Splice Variant Production

Kirsten R Palmer, Stephen Tong, Laura Tuohey, Ping Cannon, Louie Ye, Natalie J Hannan, Fiona C Brownfoot, Sebastian E Illanes, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2016  |  Biology of Reproduction

Placental-Specific sFLT-1 e15a Protein Is Increased in Preeclampsia, Antagonizes Vascular Endothelial Growth Factor Signaling, and Has Antiangiogenic Activity

Kirsten R Palmer, Tu'uhevaha J Kaitu'u-Lino, Roxanne Hastie, Natalie J Hannan, Louie Ye, Natalie Binder, Ping Cannon, Laura Tuohey, Terrance G Johns, Alexis Shub, Stephen Tong

Journal article  |  2015  |  HYPERTENSION

PAPPA2 is increased in severe early onset pre-eclampsia and upregulated with hypoxia

Kate Macintire, Laura Tuohey, Louie Ye, Kirsten Palmer, Michael Gantier, Stephen Tong, Tu'uhevaha J Kaitu'u-Lino

Journal article  |  2014  |  Reproduction, Fertility and Development

PLAC4 is upregulated in severe early onset preeclampsia and upregulated with syncytialisation but not hypoxia

L Tuohey, K Macintire, L Ye, K Palmer, M Skubisz, S Tong, TJ Kaitu'u-Lino

Journal article  |  2013  |  Placenta

MT-MMPs in pre-eclamptic placenta: Relationship to soluble endoglin production

TJ Kaitu'u-Lino, L Tuohey, L Ye, K Palmer, M Skubisz, S Tong

Journal article  |  2013  |  Placenta

MMP-15 Is Upregulated in Preeclampsia, but Does Not Cleave Endoglin to Produce Soluble Endoglin

Tu'uhevaha J Kaitu'u-Lino, Kirsten Palmer, Laura Tuohey, Louie Ye, Stephen Tong

Journal article  |  2012  |  PLOS ONE

MMP-14 Is Expressed in Preeclamptic Placentas and Mediates Release of Soluble Endoglin

Tu'uhevaha J Kaitu'u-Lino, Kirsten R Palmer, Clare L Whitehead, Elizabeth Williams, Martha Lappas, Stephen Tong

Journal article  |  2012  |  American Journal of Pathology

Ultrasound Reference Chart Based on IVF Dates to Estimate Gestational Age at 6-9 weeks' Gestation.

Pavitra Delpachitra, Kirsten Palmer, Joseph Onwude, Simon Meagher, Luk Rombauts, Karen Waalwyk, Michael Bethune, Stephen Tong

Journal article  |  2012  |  ISRN Obstetrics and Gynecology

Accurate determination of gestational age underpins good obstetric care. We assessed the performance of six existing ultrasound re..

Measurement of mRNA Transcripts of Very High Placental Expression in Maternal Blood as Biomarkers of Preeclampsia

Premila Paiva, Clare Whitehead, Burcu Saglam, Kirsten Palmer, Stephen Tong

Journal article  |  2011  |  Journal of Clinical Endocrinology & Metabolism

Is fetal growth restriction associated with a more severe maternal phenotype in the setting of early onset pre-eclampsia? A retrospective study.

Jane Weiler, Stephen Tong, Kirsten R Palmer

Journal article  |  2011  |  PLoS One

BACKGROUND: Both pre-eclampsia and fetal growth restriction are thought to result from abnormal placental implantation in early pr..