Rebecca Kelley

Anti-Mullerian hormone overexpression restricts preantral ovarian follicle survival

Michael W Pankhurst, Rebecca L Kelley, Rachel L Sanders, Savana R Woodcock, Dorothy E Oorschot, Nicola J Batchelor

Journal article  |  2018  |  Journal of Endocrinology

Anti-Müllerian hormone (AMH) is an ovarian regulator that affects folliculogenesis. AMH inhibits the developmental activation of t..

Group culture of preimplantation embryos creates a microenvironment that determines development, viability, and response to external stressors

Rebecca Lauren Kelley

Thesis / Dissertation  |  2018

Over 400,000 babies worldwide are born following in vitro fertilisation (IVF) treatment every year and millions of babies have bee..

Addition of interleukin-6 to mouse embryo culture increases blastocyst cell number and influences the inner cell mass to trophectoderm ratio

Rebecca L Kelley, David K Gardner

Journal article  |  2017  |  Clinical and experimental reproductive medicine

OBJECTIVE: In vitro culture of preimplantation embryos is improved by grouping embryos together in a drop of media. Individually c..

Impact of the IVF laboratory environment on human preimplantation embryo phenotype

DK Gardner, RL Kelley

Journal article  |  2017  |  Journal of Developmental Origins of Health and Disease

The phenotype of the human embryo conceived through in vitro fertilization (IVF), that is its morphology, developmental kinetics, ..

In vitro culture of individual mouse preimplantation embryos: the role of embryo density, microwells, oxygen, timing and conditioned media

Rebecca L Kelley, David K Gardner

Journal article  |  2017  |  Reproductive BioMedicine Online

Single embryo culture is suboptimal compared with group culture, but necessary for embryo monitoring, and culture systems should b..

Combined effects of individual culture and atmospheric oxygen on preimplantation mouse embryos in vitro

Rebecca L Kelley, David K Gardner

Journal article  |  2016  |  Reproductive BioMedicine Online

Embryos are routinely cultured individually, although this can reduce blastocyst development. Culture in atmospheric (20%) oxygen ..

Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions

Athar Aziz, E Joanna Baxter, Carol Edwards, Clara Yujing Cheong, Mitsuteru Ito, Anthony Bench, Rebecca Kelley, Yvonne Silber, Philip A Beer, Keefe Chng, Marilyn B Renfree, Kirsten McEwen, Dionne Gray, Jyoti Nangalia, Ghulam J Mufti, Eva Hellstrom-Lindberg, Jean-Jacques Kiladjian, Mary Frances McMullin, Peter J Campbell, Anne C Ferguson-Smith, et al.

Journal article  |  2013  |  Journal of Clinical Investigation

Large regions of recurrent genomic loss are common in cancers; however, with a few well-characterized exceptions, how they contrib..

Recombinant human follicle-stimulating hormone alters maternal ovarian hormone concentrations and the uterus and perturbs fetal development in mice

Rebecca L Kelley, Karen L Kind, Michelle Lane, Rebecca L Robker, Jeremy G Thompson, Lisa J Edwards

Journal article  |  2006  |  AJP Endocrinology and Metabolism

Gonadotropins are routinely administered to produce multiple oocytes for clinical in vitro fertilization (IVF) treatment, laborato..

Effect of culturing mouse embryos under different oxygen concentrations on subsequent fetal and placental development

D Feil, M Lane, CT Roberts, RL Kelley, LJ Edwards, JG Thompson, KL Kind

Journal article  |  2006  |  The Journal of Physiology

The oxygen concentration used during embryo culture can influence embryo development and quality. Reducing the oxygen concentratio..