Rebecca Kelley

Fetal resorption coincides with dysregulated LH secretion in AMH-overexpressing mice

Yiran Zhou, Christine Neyt, Nicola J Batchelor, Rebecca L Kelley, Karmilla Jaafar Amsak, Greg M Anderson, Dorothy E Oorschot, Christine L Jasoni, Jane E Girling, Michael W Pankhurst

Journal article  |  2022  |  JOURNAL OF ENDOCRINOLOGY

Female anti-Müllerian hormone (AMH) overexpressing (Thy1.2-AMHTg/0) mice experience fetal resorption (miscarriage) by mid-gestatio..

Individual culture and atmospheric oxygen during culture affect mouse preimplantation embryo metabolism and post-implantation development

Rebecca L Kelley, David K Gardner

Journal article  |  2019  |  REPRODUCTIVE BIOMEDICINE ONLINE

RESEARCH QUESTION: Does single embryo culture under atmospheric or reduced oxygen alter preimplantation metabolism and post-implan..

Anti-Mullerian hormone overexpression restricts preantral ovarian follicle survival

Michael W Pankhurst, Rebecca L Kelley, Rachel L Sanders, Savana R Woodcock, Dorothy E Oorschot, Nicola J Batchelor

Journal article  |  2018  |  JOURNAL OF ENDOCRINOLOGY

Anti-Müllerian hormone (AMH) is an ovarian regulator that affects folliculogenesis. AMH inhibits the developmental activation of t..

Group culture of preimplantation embryos creates a microenvironment that determines development, viability, and response to external stressors

Rebecca Lauren Kelley

Thesis / Dissertation  |  2018

Over 400,000 babies worldwide are born following in vitro fertilisation (IVF) treatment every year and millions of babies have bee..

Addition of interleukin-6 to mouse embryo culture increases blastocyst cell number and influences the inner cell mass to trophectoderm ratio

Rebecca L Kelley, David K Gardner

Journal article  |  2017  |  CLINICAL AND EXPERIMENTAL REPRODUCTIVE MEDICINE-CERM

OBJECTIVE: In vitro culture of preimplantation embryos is improved by grouping embryos together in a drop of media. Individually c..

Impact of the IVF laboratory environment on human preimplantation embryo phenotype

DK Gardner, RL Kelley

Journal article  |  2017  |  JOURNAL OF DEVELOPMENTAL ORIGINS OF HEALTH AND DISEASE

The phenotype of the human embryo conceived through in vitro fertilization (IVF), that is its morphology, developmental kinetics, ..

In vitro culture of individual mouse preimplantation embryos: the role of embryo density, microwells, oxygen, timing and conditioned media

Rebecca L Kelley, David K Gardner

Journal article  |  2017  |  REPRODUCTIVE BIOMEDICINE ONLINE

Single embryo culture is suboptimal compared with group culture, but necessary for embryo monitoring, and culture systems should b..

Combined effects of individual culture and atmospheric oxygen on preimplantation mouse embryos in vitro

Rebecca L Kelley, David K Gardner

Journal article  |  2016  |  REPRODUCTIVE BIOMEDICINE ONLINE

Embryos are routinely cultured individually, although this can reduce blastocyst development. Culture in atmospheric (20%) oxygen ..

MALE AND FEMALE EMBRYOS DIFFER IN THEIR RESPONSE TO OXYGEN CONCENTRATION.

DK Gardner, RL Kelley

Conference Proceedings  |  2013  |  FERTILITY AND STERILITY

Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions

Athar Aziz, E Joanna Baxter, Carol Edwards, Clara Yujing Cheong, Mitsuteru Ito, Anthony Bench, Rebecca Kelley, Yvonne Silber, Philip A Beer, Keefe Chng, Marilyn B Renfree, Kirsten McEwen, Dionne Gray, Jyoti Nangalia, Ghulam J Mufti, Eva Hellstrom-Lindberg, Jean-Jacques Kiladjian, Mary Frances McMullin, Peter J Campbell, Anne C Ferguson-Smith, et al.

Journal article  |  2013  |  JOURNAL OF CLINICAL INVESTIGATION

Large regions of recurrent genomic loss are common in cancers; however, with a few well-characterized exceptions, how they contrib..