Matthew Call

The Influence of Chimeric Antigen Receptor Structural Domains on Clinical Outcomes and Associated Toxicities

Ashleigh S Davey, Matthew E Call, Melissa J Call

Journal article  |  2021  |  Cancers

Chimeric antigen receptor (CAR)-T cell therapy has transformed the treatment of B cell malignancies, improving patient survival an..

Experimentally Guided Computational Methods Yield Highly Accurate Insights into Transmembrane Interactions within the T Cell Receptor Complex

Samyuktha Ramesh, Soohyung Park, Melissa J Call, Wonpil Im, Matthew E Call

Journal article  |  2020  |  The Journal of Physical Chemistry B

Understanding how molecular interactions within the plasma membrane govern assembly, clustering, and conformational changes in sin..

T Cell Activation Machinery: Form and Function in Natural and Engineered Immune Receptors

Nicholas J Chandler, Melissa J Call, Matthew E Call

Journal article  |  2020  |  International Journal of Molecular Sciences

The impressive success of chimeric antigen receptor (CAR)-T cell therapies in treating advanced B-cell malignancies has spurred a ..

Novel drivers and modifiers of MPL-dependent oncogenic transformation identified by deep mutational scanning

Jessica L Bridgford, Su Min Lee, Christine MM Lee, Paola Guglielmelli, Elisa Rumi, Daniela Pietra, Stephen Wilcox, Yash Chhabra, Alan F Rubin, Mario Cazzola, Alessandro M Vannucchi, Andrew J Brooks, Matthew E Call, Melissa J Call

Journal article  |  2020  |  Blood

The single transmembrane domain (TMD) of the human thrombopoietin receptor (TpoR/myeloproliferative leukemia [MPL] protein), encod..

Protein-Eye View of the in Meso Crystallization Mechanism

Leonie van't Ha, Liliana de Campo, Nhiem Tran, Anna Sokolova, Raphael Trenker, Matthew E Call, Melissa J Call, Christopher J Garvey, Anna E Leung, Tamim A Darwish, Anwen Krause-Heuer, Robert Knott, Thomas G Meikle, Calum J Drummond, Raffaele Mezzenga, Charlotte E Conn

Journal article  |  2019  |  Langmuir

A serine in the first transmembrane domain of the human E3 ubiquitin ligase MARCH9 is critical for down-regulation of its protein substrates

Cyrus Tan, Eamon FX Byrne, Casey Ah-Cann, Melissa J Call, Matthew E Call

Journal article  |  2019  |  Journal of Biological Chemistry

Structural Conservation and Effects of Alterations in T Cell Receptor Transmembrane Interfaces

Soohyung Park, Logesvaran Krshnan, Melissa J Call, Matthew E Call, Wonpil Im

Journal article  |  2018  |  Biophysical Journal

Lipidic Cubic Phase-Induced Membrane Protein Crystallization: Interplay Between Lipid Molecular Structure, Mesophase Structure and Properties, and Crystallogenesis

Alexandru Zabara, Thomas G Meikle, Raphael Trenker, Shenggen Yao, Janet Newman, Thomas S Peat, Frances Separovic, Charlotte E Conn, Melissa J Call, Matthew E Call, Ehud M Landau, Calum J Drummond

Journal article  |  2017  |  Crystal Growth & Design

Transmembrane features governing Fc receptor CD16A assembly with CD16A signaling adaptor molecules

Alfonso Blazquez-Moreno, Soohyung Park, Wonpil Im, Melissa J Call, Matthew E Call, Hugh T Reyburn

Journal article  |  2017  |  Proceedings of the National Academy of Sciences of the United States of America

Modular Activating Receptors in Innate and Adaptive Immunity

Richard Berry, Matthew E Call

Journal article  |  2017  |  Biochemistry