Sandy Shultz

The biological significance and clinical utility of emerging blood biomarkers for traumatic brain injury.

Megan E Huibregtse, Jeffrey J Bazarian, Sandy R Shultz, Keisuke Kawata

Journal article  |  2021  |  Neurosci Biobehav Rev

HUIBREGTSE, M.E, Bazarian, J.J., Shultz, S.R., and Kawata K. The biological significance and clinical utility of emerging blood bi..

Targeting the Cerebrovascular System: Next-Generation Biomarkers and Treatment for Mild Traumatic Brain Injury

Tamara L Baker, Denes V Agoston, Rhys D Brady, Brendan Major, Stuart J McDonald, Richelle Mychasiuk, David K Wright, Glenn R Yamakawa, Mujun Sun, Sandy R Shultz

Journal article  |  2021  |  NEUROSCIENTIST

The diagnosis, prognosis, and treatment of mild traumatic brain injuries (mTBIs), such as concussions, are significant unmet medic..

Is the glymphatic system the missing link between sleep impairments and neurological disorders? Examining the implications and uncertainties.

Jennaya Christensen, Glenn R Yamakawa, Sandy R Shultz, Richelle Mychasiuk

Journal article  |  2021  |  Prog Neurobiol

Until recently, both the purpose of the biological need for sleep and the mechanism by which the central nervous system eliminated..

Elevated Serum Interleukin-1 beta Levels in Male, but not Female, Collision Sport Athletes with a Concussion History

William T O'Brien, Georgia F Symons, Jesse Bain, Brendan P Major, Daniel M Costello, Mujun Sun, Joshua S Kimpton, Zhibin Chen, Rhys D Brady, Richelle Mychasiuk, Terence J O'Brien, Mastura Monif, Sandy R Shultz, Stuart J McDonald

Journal article  |  2021  |  JOURNAL OF NEUROTRAUMA

It is increasingly reported that a history of concussion may be associated with chronic deleterious consequences. While the pathop..

Prolonged elevation of serum neurofilament light after concussion in male Australian football players

Stuart J McDonald, William T O'Brien, Georgia F Symons, Zhibin Chen, Jesse Bain, Brendan P Major, Daniel Costello, Glenn Yamakawa, Mujun Sun, Rhys D Brady, Biswadev Mitra, Richelle Mychasiuk, Terence J O'Brien, Sandy R Shultz

Journal article  |  2021  |  BIOMARKER RESEARCH

BACKGROUND: Biomarkers that can objectively guide the diagnosis of sports-related concussion, and consequent return-to-play decisi..

Pain in the Developing Brain: Early Life Factors Alter Nociception and Neurobiological Function in Adolescent Rats.

Sabrina Salberg, Glenn R Yamakawa, Yannick Griep, Jesse Bain, Jaimie K Beveridge, Mujun Sun, Stuart J McDonald, Sandy R Shultz, Rhys D Brady, David K Wright, Melanie Noel, Richelle Mychasiuk

Journal article  |  2021  |  Cereb Cortex Commun

Although adverse early experiences prime individuals to be at increased risk for chronic pain, little research has examined the tr..

Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: Novel insights using a clinically relevant rat model

Louise Pham, David K Wright, William T O'Brien, Jesse Bain, Cheng Huang, Mujun Sun, Pablo M Casillas-Espinosa, Anup D Shah, Ralf B Schittenhelm, Christopher G Sobey, Rhys D Brady, Terence J O'Brien, Richelle Mychasiuk, Sandy R Shultz, Stuart J McDonald

Journal article  |  2021  |  NEUROBIOLOGY OF DISEASE

A history of mild traumatic brain injury (mTBI) is linked to a number of chronic neurological conditions, however there is still m..

Neurological heterotopic ossification: novel mechanisms, prognostic biomarkers and prophylactic therapies

Ker Rui Wong, Richelle Mychasiuk, Terence J O'Brien, Sandy R Shultz, Stuart J McDonald, Rhys D Brady

Journal article  |  2020  |  BONE RESEARCH

Neurological heterotopic ossification (NHO) is a debilitating condition where bone forms in soft tissue, such as muscle surroundin..

Contrast enhanced magnetic resonance imaging highlights neurovasculature changes following experimental traumatic brain injury in the rat

David K Wright, Jamie N Mayo, Mujun Sun, Terence J O'Brien, Sandy R Shultz

Journal article  |  2020  |  SCIENTIFIC REPORTS

Neurovascular injury has been proposed as a universal pathological hallmark of traumatic brain injury (TBI) with molecular markers..

The interaction of the circadian and immune system: Desynchrony as a pathological outcome to traumatic brain injury.

GR Yamakawa, RD Brady, M Sun, SJ McDonald, SR Shultz, R Mychasiuk

Journal article  |  2020  |  Neurobiol Sleep Circadian Rhythms

Traumatic brain injury (TBI) is a complex and costly worldwide phenomenon that can lead to many negative health outcomes including..