Yuqing Yang

HBO1 is required for the maintenance of leukaemia stem cells

Laura MacPherson, Juliana Anokye, Miriam M Yeung, Enid YN Lam, Yih-Chih Chan, Chen-Fang Weng, Paul Yeh, Kathy Knezevic, Miriam S Butler, Annabelle Hoegl, Kah-Lok Chan, Marian L Burr, Linden J Gearing, Tracy Willson, Joy Liu, Jarny Choi, Yuqing Yang, Rebecca A Bilardi, Hendrik Falk, Nguyen Nghi, et al.

Journal article  |  2020  |  NATURE

Acute myeloid leukaemia (AML) is a heterogeneous disease characterized by transcriptional dysregulation that results in a block in..

Synchrotron microbeam radiotherapy evokes a different early tumor immunomodulatory response to conventional radiotherapy in EMT6.5 mammary tumors

Yuqing Yang, Agnieszka Swierczak, Mohammad Ibahim, Premila Paiva, Leonie Cann, Andrew W Stevenson, Jeffrey C Crosbie, Robin L Anderson, Peter AW Rogers

Journal article  |  2019  |  RADIOTHERAPY AND ONCOLOGY

BACKGROUND: Synchrotron microbeam radiation therapy (MRT) is a new, evolving form of radiotherapy that has potential for clinical ..

Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth

Jonathan B Baell, David J Leaver, Stefan J Hermans, Gemma L Kelly, Margs S Brennan, Natalie L Downer, Nghi Nguyen, Johannes Wichmann, Helen M Mcrae, Yuqing Yang, Ben Cleary, H Rachel Lagiakos, Stephen Mieruszynski, Guido Pacini, Hannah K Vanyai, Maria I Bergamasco, Rose E May, Bethany K Davey, Kimberly J Morgan, Andrew J Sealey, et al.

Journal article  |  2018  |  NATURE

Acetylation of histones by lysine acetyltransferases (KATs) is essential for chromatin organization and function1. Among the genes..

MOZ (KAT6A) is essential for the maintenance of classically defined adult hematopoietic stem cells

Bilal N Sheikh, Yuqing Yang, Jaring Schreuder, Susan K Nilsson, Rebecca Bilardi, Sebastian Carotta, Helen M McRae, Donald Metcalf, Anne K Voss, Tim Thomas

Journal article  |  2016  |  BLOOD

Hematopoietic stem cells (HSCs) are conventionally thought to be at the apex of a hierarchy that produces all mature cells of the ..

An evaluation of novel real-time technology as a tool for measurement of radiobiological and radiation-induced bystander effects

Mohammad Johari Ibahim, Jeffrey C Crosbie, Premila Paiva, Yuqing Yang, Marina Zaitseva, Peter AW Rogers

Journal article  |  2016  |  RADIATION AND ENVIRONMENTAL BIOPHYSICS

The xCELLigence real-time cell impedance system uses a non-invasive and label-free method to create a cell index that is a composi..

Eosinophil-Associated Gene Pathways but not Eosinophil Numbers are Differentially Regulated between Synchrotron Microbeam Radiation Treatment and Synchrotron Broad-Beam Treatment by 48 Hours Postirradiation

MJ Ibahim, Y Yang, JC Crosbie, A Stevenson, L Cann, P Paiva, PA Rogers

Journal article  |  2016  |  RADIATION RESEARCH

Synchrotron microbeam radiation treatment (MRT) is a preclinical radiotherapy technique with considerable clinical promise, althou..

In Vitro Study of Genes and Molecular Pathways Differentially Regulated by Synchrotron Microbeam Radiotherapy

Yuqing Yang, Jeffrey C Crosbie, Premila Paiva, Mohammad Ibahim, Andrew Stevenson, Peter AW Rogers

Journal article  |  2014  |  RADIATION RESEARCH

The aim of this study was to identify genes and molecular pathways differentially regulated by synchrotron-generated microbeam rad..

An Evaluation of Dose Equivalence between Synchrotron Microbeam Radiation Therapy and Conventional Broadbeam Radiation Using Clonogenic and Cell Impedance Assays

Mohammad Johari Ibahim, Jeffrey C Crosbie, Yuqing Yang, Marina Zaitseva, Andrew W Stevenson, Peter AW Rogers, Premila Paiva

Journal article  |  2014  |  PLOS ONE

BACKGROUND: High-dose synchrotron microbeam radiation therapy (MRT) has shown the potential to deliver improved outcomes over conv..

Genome-Wide Transcription Responses to Synchrotron Microbeam Radiotherapy

Carl N Sprung, Yuqing Yang, Helen B Forrester, Jason Li, Marina Zaitseva, Leonie Cann, Tina Restall, Robin L Anderson, Jeffrey C Crosbie, Peter AW Rogers

Journal article  |  2012  |  RADIATION RESEARCH

The majority of cancer patients achieve benefit from radiotherapy. A significant limitation of radiotherapy is its relatively low ..