Dr. McMillan is the Manager of the Biological Optical Microscopy Platform at the University of Melbourne. The platform brings together the high-end optical microscopes across 10 departments within the Faculty of Medicine, Health & Dentistry and the Faculty of Science (see www.microscopy.unimelb.edu.au).
He gained his PhD in Molecular Parasitology from the University of Glasgow in 2006, before moving to La Trobe University in 2007 after receiving a La Trobe University Postdoctoral Fellowship. He relocated to the Department of Biochemistry & Molecular Biology at the University of Melbourne in 2011, before taking up the position of manager of the Biological Optical Microscopy Platform at the start of 2013.His background is in fluorescence imaging of the host/parasite interactions during malaria infections and he has experience in wide field, live cell, confocal & super-resolution microscopy methods.
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Paul McMillan's selected work
Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac ..
Role of Plasmodium falciparum Protein GEXPO7 in Maurer's Cleft Morphology, Knob Architectu..
Displaying the 5 most recent projects by Paul McMillan.
Displaying the 37 most recent scholarly works by Paul McMillan.
Sustained subcutaneous delivery of secretome of human cardiac stem cells promotes cardiac repair following myocardial infarction.
Andrew R Kompa, David W Greening, Anne M Kong, Paul J McMillan, Hoayun Fang, Ritika Saxena, Raymond CB Wong, Jarmon G Lees, Priyadharshini Sivakumaran, Andrew E Newcomb, Bakhos A Tannous, Cameron Kos, Lina Mariana, Thomas Loudovaris, Derek J Hausenloy, Shiang Y Lim
Journal article | 2020 | Cardiovascular Research
AIMS: To establish pre-clinical proof of concept that sustained subcutaneous delivery of the secretome of human cardiac stem cells..
Role of Plasmodium falciparum Protein GEXPO7 in Maurer's Cleft Morphology, Knob Architecture, and P. falciparum EMP1 Trafficking
Emma McHugh, Olivia MS Carmo, Adam Blanch, Oliver Looker, Boyin Liu, Snigdha Tiash, Dean Andrew, Steven Batinovic, Andy JY Low, Hyun-Jung Cho, Paul McMillan, Leann Tilley, Matthew WA Dixon
Journal article | 2020 | mBio
The malaria parasite Plasmodium falciparum traffics the virulence protein P. falciparum erythrocyte membrane protein 1 (PfEMP1) to..
Decreased K13 Abundance Reduces Hemoglobin Catabolism and Proteotoxic Stress, Underpinning Artemisinin Resistance
Tuo Yang, Lee M Yeoh, Madel V Tutor, Matthew W Dixon, Paul J McMillan, Stanley C Xie, Jessica L Bridgford, David L Gillett, Michael F Duffy, Stuart A Ralph, Malcolm J McConville, Leann Tilley, Simon A Cobbold
Journal article | 2019 | Cell Reports
Essential role of Plasmodium perforin-like protein 4 in ookinete midgut passage
Elena Deligianni, Natalie C Silmon de Monerri, Paul J McMillan, Lucia Bertuccini, Fabiana Superti, Maria Manola, Lefteris Spanos, Christos Louis, Michael J Blackman, Leann Tilley, Inga Siden-Kiamos
Journal article | 2018 | PLOS ONE
Viral regulation of host cell biology by hijacking of the nucleolar DNA-damage response
Stephen M Rawlinson, Tianyue Zhao, Ashley M Rozario, Christina L Rootes, Paul J McMillan, Anthony W Purcell, Amanda Woon, Glenn A Marsh, Kim G Lieu, Lin-Fa Wang, Hans J Netter, Toby DM Bell, Cameron R Stewart, Gregory W Moseley
Journal article | 2018 | Nature Communications
Disrupting assembly of the inner membrane complex blocks Plasmodium falciparum sexual stage development
Molly Parkyn Schneider, Boyin Liu, Philipp Glock, Annika Suttie, Emma McHugh, Dean Andrew, Steven Batinovic, Nicholas Williamson, Eric Hanssen, Paul McMillan, Marion Hliscs, Leann Tilley, Matthew WA Dixon
Journal article | 2017 | PLOS Pathogens
A repeat sequence domain of the ring-exported protein-1 of Plasmodium falciparum controls export machinery architecture and virulence protein trafficking
Emma McHugh, Steven Batinovic, Eric Hanssen, Paul J McMillan, Shannon Kenny, Michael DW Griffin, Simon Crawford, Katharine R Trenholme, Donald L Gardiner, Matthew WA Dixon, Leann Tilley
Journal article | 2015 | Molecular Microbiology
Renal participation of myeloperoxidase in antineutrophil cytoplasmic antibody (ANCA)-associated glomerulonephritis
Kim M O'Sullivan, Camden Y Lo, Shaun A Summers, Kirstin D Elgass, Paul J McMillan, Anthony Longano, Sharon L Ford, Poh-Yi Gan, Peter G Kerr, A Richard Kitching, Stephen R Holdsworth
Journal article | 2015 | Kidney International
Differential use of autophagy by primary dendritic cells specialized in cross-presentation
Justine D Mintern, Christophe Macri, Wei Jin Chin, Scott E Panozza, Elodie Segura, Natalie L Patterson, Peter Zeller, Dorothee Bourges, Sammy Bedoui, Paul J McMillan, Adi Idris, Cameron J Nowell, Andrew Brown, Kristen J Radford, Angus PR Johnston, Jose A Villadangos
Journal article | 2015 | Autophagy
Detailed morphological characterisation of Hendra virus infection of different cell types using super-resolution and conventional imaging
Paul Monaghan, Diane Green, Jackie Pallister, Reuben Klein, John White, Catherine Williams, Paul McMillan, Leann Tilley, Marko Lampe, Pippa Hawes, Lin-Fa Wang
Journal article | 2014 | Virology Journal
Spatial and temporal mapping of the PfEMP1 export pathway in Plasmodium falciparum
Paul J McMillan, Coralie Millet, Steven Batinovic, Mauro Maiorca, Eric Hanssen, Shannon Kenny, Rebecca A Muhle, Martin Melcher, David A Fidock, Joseph D Smith, Matthew WA Dixon, Leann Tilley
Journal article | 2013 | Cellular Microbiology
An atypical cyclin-dependent kinase controls Plasmodium falciparum proliferation rate
Dominique Dorin-Semblat, Teresa Gil Carvalho, Marie-Paule Nivez, Jean Halbert, Patrick Poullet, Jean-Philippe Semblat, Dean Goldring, Debopam Chakrabarti, Parul Mehra, Suman Dhar, May M Paing, Daniel E Goldberg, Paul J McMillan, Leann Tilley, Christian Doerig
Journal article | 2013 | Kinome
Co-ordinated stage-dependent enhancement of Plasmodium falciparum antioxidant enzymes and heat shock protein expression in parasites growing in oxidatively stressed or G6PD-deficient red blood cells
Oscar Bate Akide-Ndunge, Elisa Tambini, Giuliana Giribaldi, Paul J McMillan, Sylke Muller, Paolo Arese, Francesco Turrini
Journal article | 2009 | Malaria Journal
Targeted mutagenesis of the ring-exported protein-1 of Plasmodium falciparum disrupts the architecture of Maurer's cleft organelles
Eric Hanssen, Paula Hawthorne, Matthew WA Dixon, Katharine R Trenholme, Paul J McMillan, Tobias Spielmann, Donald L Gardiner, Leann Tilley
Journal article | 2008 | Molecular Microbiology
Inhibition of high M-r and low M-r thioredoxin reductases from Plasmodium falciparum and Trichomonas vaginalis by organotellurides.
Paul J McMillan, Susan E Young, Eva-Maria Patzewitz, Gareth D Westrop, Graham H Coombs, Lars Engman, Sylke Muller
Conference Proceedings | 2008 | INTERNATIONAL JOURNAL FOR PARASITOLOGY
Structural and biochemical characterization of a mitochondrial peroxiredoxin from Plasmodium falciparum
Ian W Boucher, Paul J McMillan, Mads Gabrielsen, Susan E Akerman, James A Brannigan, Claudia Schnick, Andrzej M Brzozowski, Anthony J Wilkinson, Sylke Muller
Journal article | 2006 | Molecular Microbiology
Mapping and identification of essential gene functions on the X chromosome of Drosophila
A Peter, P Schottler, M Werner, N Beinert, G Dowe, P Burkert, F Mourkioti, L Dentzer, YC He, P Deak, PV Benos, MK Gatt, L Murphy, D Harris, B Barrell, C Ferraz, S Vidal, C Brun, J Demaille, E Cadieu, et al.
Journal article | 2002 | EMBO reports
From first base: The sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies
PV Benos, MK Gatt, L Murphy, D Harris, B Barrell, C Ferraz, S Vidal, C Brun, J Demaille, E Cadieu, S Dreano, S Gloux, V Lelaure, S Mottier, F Galibert, D Borkova, B Minana, FC Kafatos, S Bolshakov, I Siden-Kiamos, et al.
Journal article | 2001 | Genome Research
From sequence to chromosome: The tip of the X chromosome of D. melanogaster
PV Benos, MK Gatt, M Ashburner, L Murphy, D Harris, B Barrell, C Ferraz, S Vidal, C Brun, J Demailles, E Cadieu, S Dreano, S Gloux, V Lelaure, S Mottier, F Galibert, D Borkova, B Minana, FC Kafatos, C Louis, et al.
Journal article | 2000 | Science