Rhiannon Wood

Remodelling of myelinated axons and oligodendrocyte differentiation is stimulated by environmental enrichment in the young adult brain

Madeline Nicholson, Rhiannon J Wood, David G Gonsalvez, Anthony J Hannan, Jessica L Fletcher, Junhua Xiao, Simon S Murray

Journal article  |  2022  |  EUROPEAN JOURNAL OF NEUROSCIENCE

Oligodendrocyte production and myelination continues lifelong in the central nervous system (CNS), and all stages of this process ..

Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury (vol 339, 113652, 2021)

Jessica L Fletcher, Larissa K Dill, Rhiannon J Wood, Sharon Wang, Kate Robertson, Simon S Murray, Akram Zamani, Bridgette D Semple

Journal article  |  2021  |  EXPERIMENTAL NEUROLOGY

The authors regret the inclusion of a calculation error, in results section 3.6 (Fig. 5a and b), regarding cortical and hippocampa..

CSF infusion of TrkB agonist, 7,8-dihydroxyflavone, is ineffective in promoting remyelination in cuprizone and EAE models of multiple sclerosis

Jessica Fletcher, Rhiannon Wood, Alexa Prawdiuk, Ryan O’Rafferty, Ophelia Ehrlich, David Gonsalvez, Simon Murray

Journal article  |  2021

Small molecular weight functional mimetics of brain-derived neurotrophic factor (BDNF) which act via the TrkB receptor have been d..

Acute treatment with TrkB agonist LM22A-4 confers neuroprotection and preserves myelin integrity in a mouse model of pediatric traumatic brain injury

Jessica L Fletcher, Larissa K Dill, Rhiannon J Wood, Sharon Wang, Kate Robertson, Simon S Murray, Akram Zamani, Bridgette D Semple

Journal article  |  2021  |  EXPERIMENTAL NEUROLOGY

Young children have a high risk of sustaining a traumatic brain injury (TBI), which can have debilitating life-long consequences. ..

Partial deletion of p75(NTR)in large-diameter DRG neurons exerts no influence upon the survival of peripheral sensory neuronsin vivo

Zuoheng Qin, David G Gonsalvez, Rhiannon J Wood, Fatemeh Daemi, Sangwon Yoo, Jason J Ivanusic, Elizabeth J Coulson, Simon S Murray, Junhua Xiao

Journal article  |  2020  |  JOURNAL OF NEUROSCIENCE RESEARCH

The p75 neurotrophin receptor (p75NTR ) is required for maintaining peripheral sensory neuron survival and function; however, the ..

The dynamics of oligodendrocyte generation: how distinct is the mouse from the human?

David Gonsalvez, Georgina Craig, Darragh Walsh, Barry Hughes, Rhiannon Wood, Sang Won Yoo, Simon Murray, Junhua Xiao

Journal article  |  2019

Murine oligodendrocyte generation dynamics are considered distinct from those in the human, with implications for cross-species di..

Imaging and Quantification of Myelin Integrity After Injury With Spectral Confocal Reflectance Microscopy

David G Gonsalvez, SangWon Yoo, Jessica L Fletcher, Rhiannon J Wood, Georgina A Craig, Simon S Murray, Junhua Xiao

Journal article  |  2019  |  FRONTIERS IN MOLECULAR NEUROSCIENCE

Developing a high-throughput approach to quantify the extent of myelin integrity in preclinical models of demyelinating diseases w..

TrkB Agonist LM22A-4 Increases Oligodendroglial Populations During Myelin Repair in the Corpus Callosum

Huynh TH Nguyen, Rhiannon J Wood, Alexa R Prawdiuk, Sebastian GB Furness, Junhua Xiao, Simon S Murray, Jessica L Fletcher

Journal article  |  2019  |  FRONTIERS IN MOLECULAR NEUROSCIENCE

The neurotrophin, brain-derived neurotrophic factor (BDNF) promotes central nervous system (CNS) myelination during development an..

Impaired myelin repair in the brain of young adult mice following repeat-insult demyelination

JL Fletcher, R Wood, H Nguyen, O Ehrlich, A Govier-Cole, J Xiao, S Murray

Conference Proceedings  |  2019  |  GLIA

TRKB AGONISM CONFERS NEUROPROTECTION IN A MOUSE MODEL OF PEDIATRIC TRAUMATIC BRAIN INJURY

Bridgette Semple, Larissa Dill, Kate Robertson, Sharon Wang, Akram Zamani, Rhiannon Wood, Simon Murray, Jessica Fletcher

Conference Proceedings  |  2019  |  JOURNAL OF NEUROTRAUMA