Richard Tothill

Novel RET Fusion RET-SEPTIN9 Predicts Response to Selective RET Inhibition With Selpercatinib in Malignant Pheochromocytoma

Angela Mweempwa, Huiling Xu, Joseph HA Vissers, Richard W Tothill, Andrew D Pattison, Andrew P Fellowes, David M Thomas, Gary Richardson, Rodney J Hicks, Sean M Grimmond, Stephen B Fox, Stephen J Luen, Jayesh Desai, Benjamin J Solomon

Journal article  |  2021  |  JCO Precision Oncology

gamma delta T Cells in Merkel Cell Carcinomas Have a Proinflammatory Profile Prognostic of Patient Survival

Nicholas A Gherardin, Kelly Waldeck, Alex Caneborg, Luciano G Martelotto, Shiva Balachander, Magnus Zethoven, Pasquale M Petrone, Andrew Pattison, James S Wilmott, Sergio M Quinones-Parra, Fernando Rossello, Atara Posner, Annie Wong, Alison M Weppler, Kerwin F Shannon, Angela Hong, Peter M Ferguson, Valerie Jakrot, Jeanette Raleigh, Athena Hatzimihalis, et al.

Journal article  |  2021  |  CANCER IMMUNOLOGY RESEARCH

Merkel cell carcinomas (MCC) are immunogenic skin cancers associated with viral infection or UV mutagenesis. To study T-cell infil..

FAPI PET/CT: Will It End the Hegemony of F-18-FDG in Oncology?

Rodney J Hicks, Peter J Roselt, Kumarswamy G Kallur, Richard W Tothill, Linda Mileshkin

Journal article  |  2021  |  JOURNAL OF NUCLEAR MEDICINE

For over 40 years, 18F-FDG has been the dominant PET tracer in neurology, cardiology, inflammatory diseases, and, most particularl..

Towards Routine Implementation of Liquid Biopsies in Cancer Management: It Is Always Too Early, until Suddenly It Is Too Late

Maarten J IJzerman, Jasper de Boer, Arun Azad, Koen Degeling, Joel Geoghegan, Chelsee Hewitt, Frederic Hollande, Belinda Lee, Yat Ho To, Richard W Tothill, Gavin Wright, Jeanne Tie, Sarah-Jane Dawson

Journal article  |  2021  |  DIAGNOSTICS

Blood-based liquid biopsies are considered a new and promising diagnostic and monitoring tool for cancer. As liquid biopsies only ..

CUP-AI-Dx: A tool for inferring cancer tissue of origin and molecular subtype using RNA gene-expression data and artificial intelligence

Yue Zhao, Ziwei Pan, Sandeep Namburi, Andrew Pattison, Atara Posner, Shiva Balachander, Carolyn A Paisie, Honey Reddi, Jens Rueter, Anthony J Gill, Stephen Fox, Kanwal PS Raghav, William F Flynn, Richard W Tothill, Sheng Li, R Krishna Murthy Karuturi, Joshy George

Journal article  |  2020  |  EBIOMEDICINE

BACKGROUND: Cancer of unknown primary (CUP), representing approximately 3-5% of all malignancies, is defined as metastatic cancer ..

A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb /- rats (vol 27, pg 337, 2020)

James F Powers, Brent Cochran, James D Baleja, Hadley D Sikes, Andrew D Pattison, Xue Zhang, Inna Lomakin, Annette Shepard-Barry, Karel Pacak, Sun Jin Moon, Troy F Langford, Kassi Taylor Stein, Richard W Tothill, Yingbin Ouyang, Arthur S Tischler

Journal article  |  2020  |  ENDOCRINE-RELATED CANCER

The authors and journal apologise for an error in the above paper, which appeared in volume 27 part 6, pages 337-354. The error re..

The changing paradigm of managing Merkel cell carcinoma in Australia: An expert commentary

David L Kok, Annie Wang, Wen Xu, Margaret ST Chua, Alexander Guminski, Michael Veness, Julie Howle, Richard Tothill, Ganessan Kichendasse, Michael Poulsen, Shahneen Sandhu, Gerald Fogarty

Journal article  |  2020  |  ASIA-PACIFIC JOURNAL OF CLINICAL ONCOLOGY

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine tumor of the skin with an estimated disease-associated mortality..

Enhancing the anti-tumour activity of 177Lu-DOTA-octreotate radionuclide therapy in somatostatin receptor-2 expressing tumour models by targeting PARP

Carleen Cullinane, Kelly Waldeck, Laura Kirby, Buck E Rogers, Peter Eu, Richard W Tothill, Rodney J Hicks

Journal article  |  2020  |  SCIENTIFIC REPORTS

Peptide receptor radionuclide therapy (PRRT) is an important treatment option for patients with somatostatin receptor-2 (SSTR2)-ex..

A xenograft and cell line model of SDH-deficient pheochromocytoma derived from Sdhb plus /- rats

James F Powers, Brent Cochran, James D Baleja, Hadley D Sikes, Andrew D Pattison, Xue Zhang, Inna Lomakin, Annette Shepard-Barry, Karel Pacak, Sun Jin Moon, Troy F Langford, Kassi Taylor Stein, Richard W Tothill, Yingbin Ouyang, Arthur S Tischler

Journal article  |  2020  |  ENDOCRINE-RELATED CANCER

Tumors caused by loss-of-function mutations in genes encoding TCA cycle enzymes have been recently discovered and are now of great..

Identifying biomarkers to guide immunotherapy treatment of cancer of unknown primary.

Linda R Mileshkin, Atara Posner, Andrew Pattison, Shiva Balachander, Dariush Etemadmoghadam, Andrew Fellowes, Hui Li Wong, Eryn Dow, Anna DeFazio, Bo Gao, Christos Stelios Karapetis, Madhu Sudan Singh, Ian M Collins, Christopher Steer, Mark Andrew Warren, Narayan Karanth, David Bowtell, Owen WJ Prall, Richard Tothill

Conference Proceedings  |  2020  |  JOURNAL OF CLINICAL ONCOLOGY

e15252 Background: Cancer of unknown primary (CUP) is a metastatic cancer where the primary tissue of origin (ToO) evades detecti..