Claire Gorrie

Hidden Resistances: How Routine Whole-Genome Sequencing Uncovered an Otherwise Undetected bla(NDM-1) Gene in Vibrio alginolyticus from Imported Seafood

Jacqueline MM Morris, Karolina Mercoulia, Mary Valcanis, Claire LL Gorrie, Norelle LL Sherry, Benjamin PP Howden

Journal article  |  2023  |  MICROBIOLOGY SPECTRUM

Vibrio alginolyticus causes vibriosis of marine vertebrates, invertebrates, and humans, and while there have been several reports ..

An ISO-certified genomics workflow for identification and surveillance of antimicrobial resistance.

Norelle L Sherry, Kristy A Horan, Susan A Ballard, Anders Gonҫalves da Silva, Claire L Gorrie, Mark B Schultz, Kerrie Stevens, Mary Valcanis, Michelle L Sait, Timothy P Stinear, Benjamin P Howden, Torsten Seemann

Journal article  |  2023  |  Nat Commun

Realising the promise of genomics to revolutionise identification and surveillance of antimicrobial resistance (AMR) has been a lo..

104. Dissemination of Carbapenemase-producing Enterobacterales positive patients through the health system: A linkage study

Michael Lydeamore, Tjibbe Donker, Ben Cooper, Marion Easton, Nicolas Geard, Claire Gorrie, Daneeta Hennessy, Benjamin Howden, Anton Peleg, Annabelle Turner, Andrew Wilson, Andrew Stewardson

Journal article  |  2022  |  Infection, Disease & Health

Genomic dissection of Klebsiella pneumoniae infections in hospital patients reveals insights into an opportunistic pathogen

Claire L Gorrie, Mirjana Mirceta, Ryan R Wick, Louise M Judd, Margaret MC Lam, Ryota Gomi, Iain J Abbott, Nicholas R Thomson, Richard A Strugnell, Nigel F Pratt, Jill S Garlick, Kerrie M Watson, Peter C Hunter, David V Pilcher, Steve A McGloughlin, Denis W Spelman, Kelly L Wyres, Adam WJ Jenney, Kathryn E Holt

Journal article  |  2022  |  NATURE COMMUNICATIONS

Klebsiella pneumoniae is a major cause of opportunistic healthcare-associated infections, which are increasingly complicated by th..

Klebsiella pneumoniae induces host metabolic stress that promotes tolerance to pulmonary infection

Tania Wong Fok Lung, Daniel Charytonowicz, Kristin G Beaumont, Shivang S Shah, Shwetha H Sridhar, Claire L Gorrie, Andre Mu, Casey E Hofstaedter, David Varisco, Thomas H McConville, Marija Drikic, Brandon Fowler, Andreacarola Urso, Wei Shi, Dario Fucich, Medini K Annavajhala, Ibrahim N Khan, Irina Oussenko, Nancy Francoeur, Melissa L Smith, et al.

Journal article  |  2022  |  CELL METABOLISM

K. pneumoniae sequence type 258 (Kp ST258) is a major cause of healthcare-associated pneumonia. However, it remains unclear how it..

Multi-site implementation of whole genome sequencing for hospital infection control: A prospective genomic epidemiological analysis

Norelle L Sherry, Claire L Gorrie, Jason C Kwong, Charlie Higgs, Rhonda L Stuart, Caroline Marshall, Susan A Ballard, Michelle Sait, Tony M Korman, Monica A Slavin, Robyn S Lee, Maryza Graham, Marcel Leroi, Leon J Worth, Hiu Tat Chan, Torsten Seemann, M Lindsay Grayson, Benjamin P Howden

Journal article  |  2022  |  LANCET REGIONAL HEALTH-WESTERN PACIFIC

BACKGROUND: Current microbiological methods lack the resolution to accurately identify multidrug-resistant organism (MDRO) transmi..

Optimising genomic approaches for identifying vancomycin-resistant Enterococcus faecium transmission in healthcare settings

Charlie Higgs, Norelle L Sherry, Torsten Seemann, Kristy Horan, Hasini Walpola, Paul Kinsella, Katherine Bond, Deborah A Williamson, Caroline Marshall, Jason C Kwong, M Lindsay Grayson, Timothy P Stinear, Claire L Gorrie, Benjamin P Howden

Journal article  |  2022  |  NATURE COMMUNICATIONS

Vancomycin-resistant Enterococcus faecium (VREfm) is a major nosocomial pathogen. Identifying VREfm transmission dynamics permits ..

Search and Contain: Impact of an Integrated Genomic and Epidemiological Surveillance and Response Program for Control of Carbapenemase-producing Enterobacterales

Courtney R Lane, Judith Brett, Mark Schultz, Claire L Gorrie, Kerrie Stevens, Donna RM Cameron, Siobhan St George, Annaliese van Diemen, Marion Easton, Rhonda L Stuart, Michelle Sait, Anton Y Peleg, Andrew J Stewardson, Allen C Cheng, Denis W Spelman, Mary Jo Waters, Susan A Ballard, Norelle L Sherry, Deborah A Williamson, Finn Romanes, et al.

Journal article  |  2021  |  CLINICAL INFECTIOUS DISEASES

BACKGROUND: Multiresistant organisms (MROs) pose a critical threat to public health. Population-based programs for control of MROs..

Key parameters for genomics-based real-time detection and tracking of multidrug-resistant bacteria: a systematic analysis

Claire L Gorrie, Anders Goncalves Da Silva, Danielle J Ingle, Charlie Higgs, Torsten Seemann, Timothy P Stinear, Deborah A Williamson, Jason C Kwong, M Lindsay Grayson, Norelle L Sherry, Benjamin P Howden

Journal article  |  2021  |  LANCET MICROBE

BACKGROUND: Pairwise single nucleotide polymorphisms (SNPs) are a cornerstone of genomic approaches to the inference of transmissi..

Daptomycin Resistance Occurs Predominantly in vanA-Type Vancomycin-Resistant Enterococcus faecium in Australasia and Is Associated With Heterogeneous and Novel Mutations

Lucy Li, Charlie Higgs, Adrianna M Turner, Yi Nong, Claire L Gorrie, Norelle L Sherry, Kristin H Dyet, Torsten Seemann, Deborah A Williamson, Timothy P Stinear, Benjamin P Howden, Glen P Carter

Journal article  |  2021  |  FRONTIERS IN MICROBIOLOGY

Healthcare associated infections caused by vancomycin-resistant Enterococcus faecium (VREfm) have a major impact on health outcome..