Nic Geard

PoLoBag: Polynomial Lasso Bagging for signed gene regulatory network inference from expression data.

Gourab Ghosh Roy, Nicholas Geard, Karin Verspoor, Shan He

Journal article  |  2020  |  Bioinformatics

MOTIVATION: Inferring gene regulatory networks (GRNs) from expression data is a significant systems biology problem. A useful infe..

Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection

Rebecca H Chisholm, Nikki Sonenberg, Jake A Lacey, Malcolm I McDonald, Manisha Pandey, Mark R Davies, Steven YC Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2020  |  PLOS COMPUTATIONAL BIOLOGY

Group A Streptococcus (GAS) skin infections are caused by a diverse array of strain types and are highly prevalent in disadvantage..

Longitudinal Analysis of Group A Streptococcus emm Types and emm Clusters in a High-Prevalence Setting: Relationship between Past and Future Infections.

Patricia Therese Campbell, Steven YC Tong, Nicholas Geard, Mark R Davies, Kate A Worthing, Jake A Lacey, Pierre R Smeesters, Michael R Batzloff, Joseph Kado, Adam WJ Jenney, Jodie Mcvernon, Andrew C Steer

Journal article  |  2020  |  The Journal of Infectious Diseases

Group A Streptococcus is a pathogen of global importance, but despite the ubiquity of group A Streptococcus infections, the relati..

Assessing the risk of spread of COVID-19 to the Asia Pacificregion

Freya Shearer, James Walker, Nefel Tellioglu, James McCaw, Jodie McVernon, Andrew Black, Nic Geard

Journal article  |  2020

Abstract During the early stages of an emerging disease outbreak, governments are required to make critical decisions on how to re..

A model of population dynamics with complex household structure and mobility: implications for transmission and control of communicable diseases.

Rebecca H Chisholm, Bradley Crammond, Yue Wu, Asha C Bowen, Patricia T Campbell, Steven YC Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2020  |  PeerJ

Households are known to be high-risk locations for the transmission of communicable diseases. Numerous modelling studies have demo..

Profiling Mycobacterium tuberculosis transmission and the resulting disease burden in the five highest tuberculosis burden countries

Romain Ragonnet, James M Trauer, Nicholas Geard, Nick Scott, Emma S McBryde

Journal article  |  2019  |  BMC MEDICINE

BACKGROUND: Tuberculosis (TB) control efforts are hampered by an imperfect understanding of TB epidemiology. The true age distribu..

Optimal timing of influenza vaccine during pregnancy: A systematic review and meta-analysis

Will Cuningham, Nicholas Geard, James E Fielding, Sabine Braat, Shabir A Madhi, Marta C Nunes, Lisa M Christian, Shin-Yu Lin, Chien-Nan Lee, Koushi Yamaguchi, Hans Bisgaard, Bo Chawes, An-Shine Chao, Geraldine Blanchard-Rohner, Elizabeth P Schlaudecker, Barbra M Fisher, Jodie McVernon, Robert Moss

Journal article  |  2019  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

BACKGROUND: Pregnant women have an elevated risk of illness and hospitalisation from influenza. Pregnant women are recommended to ..

Epidemiological consequences of enduring strain-specific immunity requiring repeated episodes of infection

Rebecca Chisholm, Nikki Sonenberg, Jake Lacey, Malcolm McDonald, Manisha Pandey, Mark Davies, Steven Tong, Jodie McVernon, Nicholas Geard

Journal article  |  2019

Abstract Group A Streptococcus (GAS) skin infections are caused by a diverse array of strain types and are highly prevalent in Ind..

GEOFIL: A spatially-explicit agent-based modelling framework for predicting the long-term transmission dynamics of lymphatic filariasis in American Samoa

Zhijing Xu, Patricia M Graves, Colleen L Lau, Archie Clements, Nicholas Geard, Kathryn Glass

Journal article  |  2019  |  Epidemics

In this study, a spatially-explicit agent-based modelling framework GEOFIL was developed to predict lymphatic filariasis (LF) tran..

What can urban mobility data reveal about the spatial distribution of infection in a single city?

Robert Moss, Elham Naghizade, Martin Tomko, Nicholas Geard

Journal article  |  2019  |  BMC Public Health

Background Infectious diseases spread through inherently spatial processes. Road and air traffic data have been used to model thes..