Paul is employed as the Assistant Dean, The University of Melbourne Academic Centre, Royal Children's Hospital; Stevenson Professor and Head of Department of Paediatrics, The University of Melbourne. He is also a Paediatric Haematologist at the Royal Children’s Hospital.
Paul graduated from Monash Medical School with honours in 1988. He achieved dual Fellowship of RACP/RCPA in 1997 as a paediatric haematologist. His MD (Monash) was completed in 2003 and he obtained Fellowship of ACCP in 2001. During 1996-98 Paul worked as a Research Fellow in the Department of Paediatrics, McMaster University, Hamilton Ontario, completing a Masters of Science (Health Research Methodology).
Paul returned to Melbourne in 1998 to commence as Laboratory Haematologist, Women’s and Children’s Health Care Network. Within 12 months Paul was appointed Acting Director, Division of Laboratory Services and subsequently was formally appointed Director and was charged with rebuilding Laboratory Services. This was a successful process with considerable improvements achieved in quality systems, clinical interfacing, management and financial accountability. In 2001 Paul was awarded the RCH Gold Medal, the youngest ever recipient, for his efforts in dealing with the organ retention after autopsy issue.
Paul has remained an active educator, being involved in undergraduate and post graduate teaching.
Paul is a reviewer for many international journals and has published extensively in the fields of developmental haemostasis and paediatric thrombosis and anticoagulation, co authoring the only major textbook in the field (Thromboembolic complications during infancy and childhood. Andrew M, Monagle P, Brooker L. Decker Inc. 2000) as well as multiple chapters in other major textbooks. Paul has significant international collaborations and has published over 110 peer reviewed papers, in addition to numerous reviews.
Paul is recognised internationally for his clinical service and is the current Chair, American College of Chest Physicians (ACCP) Antithrombotic Guidelines, paediatric chapter and in 2012 completed a tenure as Chair, ISTH (International Society Thrombosis Haemostasis) Paediatric/Perinatal Subcommittee. He is a Director of the Murdoch Childrens Research Institute and Royal Children’s Hospital Foundation. Paul is a member of University of Melbourne Academic Programs committee.
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Salary Contribution - Scholarship Contribution - Monsorul Hoq 18/19- Proj Determining Age..
Challenges and Opportunities in the Pharmacological Treatment of Acute Venous Thromboembol..
A Novel Point Of Care (Poc) Device For Predicting And Monitoring Bleeding And Clotting (Ha..
Displaying the 18 most recent projects by Paul Monagle.
Improving Functional Outcomes After Fontan Surgery By A Cross-Sectional Study Of The Outcomes Following Variation In Practice In Australia And New Zealand: Focus On Anticoagulation And Cardiac Shunting By The Fenestration
The Fontan procedure is the last of a series of life-saving operations offered to children born with only one pumping chamber in their heart..
Internal Research Grant
Displaying the 380 most recent scholarly works by Paul Monagle.
Age-specific differences in the in vitro anticoagulant effect of Bivalirudin in healthy neonates and children compared to adults.
Natasha Letunica, Xavier Busuttil-Crellin, Jessica Cowley, Paul Monagle, Vera Ignjatovic
Journal article | 2020 | Thrombosis Research
Bivalirudin is a reversible direct thrombin inhibitor that inhibits both bound and free thrombin and binds to the active (catalyti..
Challenges and Opportunities in the Pharmacological Treatment of Acute Venous Thromboembolism in Children
Carly George, Marzia Rahman, Paul Monagle
Journal article | 2020 | Pediatric Drugs
Venous thromboembolism (VTE) is an important but historically under-recognized problem in pediatrics, with an incidence concentrat..
Rivaroxaban for treatment of pediatric venous thromboembolism. An Einstein-Jr phase 3 dose-exposure-response evaluation
Guy Young, Anthonie WA Lensing, Paul Monagle, Christoph Male, Kirstin Thelen, Stefan Willmann, Joseph S Palumbo, Riten Kumar, Ildar Nurmeev, Kerry Hege, Fanny Bajolle, Philip Connor, Helene L Hooimeijer, Marcela Torres, Anthony KC Chan, Gili Kenet, Susanne Holzhauer, Amparo Santamaria, Pascal Amedro, Jan Beyer-Westendorf, et al.
Journal article | 2020 | Journal of Thrombosis and Haemostasis
BACKGROUND: Recently, the randomized EINSTEIN-Jr study showed similar efficacy and safety for rivaroxaban and standard anticoagula..
Defining the path ahead for NOAC use in the pediatric population: A Cardiac Safety Research Consortium Think Tank
Jonathan H Seltzer, Ann Farrell, Neil Goldenberg, Christoph Hornik, Daniel Keene, Mitchell W Krucoff, Concetta Lipardi, Patricia Massicotte, Dirk Mentzer, Paul Monagle, Courtney Thornburg, James H Revkin, Shetarra Walker, Diptee Gajjar
Journal article | 2020 | American Heart Journal
Plasma Proteomic Analysis Reveals Age-Specific Changes in Platelet- and Endothelial Cell-Derived Proteins and Regulators of Plasma Coagulation and Fibrinolysis
Conor McCafferty, Xavier Busuttil-Crellin, Tengyi Cai, Paul Monagle, Neil A Goldenberg, Vera Ignjatovic
Journal article | 2020 | The Journal of Pediatrics
This post hoc study of a plasma proteomic database investigated hemostatic proteins in the context of developmental hemostasis. Tw..
Hot topics in coagulation testing: Important considerations for testing children for bleeding/thrombotic disorders
Marzia Rahman, Carly George, Paul Monagle
Journal article | 2020 | International Journal of Laboratory Hematology
The accurate use and interpretation of diagnostic investigations are essential for safe and effective patient care. Appropriate ap..
Reference intervals for serum cystatin C in neonates and children 30 days to 18 years old
Tengyi Cai, Vasiliki Karlaftis, Stephen Hearps, Susan Matthews, Janet Burgess, Paul Monagle, Vera Ignjatovic
Journal article | 2020 | Pediatric Nephrology
BACKGROUND: Serum cystatin C (CysC) is a promising biomarker of kidney function, which has higher accuracy and sensitivity when co..
Thrombin dynamics in children with liver disease or extrahepatic portal vein obstruction or shunt
William Beattie, Romy Kremers, Maria Magnusson, Tessa Peters, Bas de Laat, Winita Hardikar, Paul Monagle, Vera Ignjatovic
Journal article | 2020 | Thrombosis Research
INTRODUCTION: Changes in the coagulation profile in children with liver disease and extrahepatic portal vein obstruction or shunt ..
Cognitive resilience following paediatric stroke: Biological and environmental predictors
Vicki Anderson, Simone Darling, Mark Mackay, Paul Monagle, Mardee Greenham, Anna Cooper, Rod W Hunt, Stephen Hearps, Anne L Gordon
Journal article | 2020 | European Journal of Paediatric Neurology
Little is known about resilience after paediatric stroke (PS), or the factors that contribute to better outcomes. Rather, research..
Anticoagulant Heparin Mimetics via RAFT Polymerization
Abdullah Al Nahain, Vera Ignjatovic, Paul Monagle, John Tsanaktsidis, George Vamvounis, Vito Ferro
Journal article | 2020 | Biomacromolecules
Heparin, a sulfated polysaccharide derived from animal sources, is the most commonly used parenteral anticoagulant drug, but it su..
Method article: guidelines for panel design, optimization, and performance of whole blood multi-color flow cytometry of platelet surface markers
Xavier Busuttil-Crellin, Conor McCafferty, Suelyn Van Den Helm, Hui Ping Yaw, Paul Monagle, Matthew Linden, Vera Ignjatovic
Journal article | 2020 | Platelets
Flow cytometry is a valuable tool in determining the phenotype and function of platelets accurately. The emergence of platelet flo..
Rivaroxaban compared with standard anticoagulants for the treatment of acute venous thromboembolism in children: a randomised, controlled, phase 3 trial
Christoph Male, Anthonie WA Lensing, Joseph S Palumbo, Riten Kumar, Ildar Nurmeev, Kerry Hege, Damien Bonnet, Philip Connor, Helene L Hooimeijer, Marcela Torres, Anthony KC Chan, Gili Kenet, Susanne Holzhauer, Amparo Santamaria, Pascal Amedro, Elizabeth Chalmers, Paolo Simioni, Rukhmi V Bhat, Donald L Yee, Olga Lvova, et al.
Journal article | 2020 | The Lancet Haematology
BACKGROUND: Treatment of venous thromboembolism in children is based on data obtained in adults with little direct documentation o..
Management of People With a Fontan Circulation: a Cardiac Society of Australia and New Zealand Position Statement
Dominica Zentner, David S Celermajer, Thomas Gentles, Yves d'Udekem, Julian Ayer, Gillian M Blue, Cameron Bridgman, Luke Burchill, Michael Cheung, Rachael Cordina, Evelyn Culnane, Andrew Davis, Karin du Plessis, Karen Eagleson, Kirsten Finucane, Belinda Frank, Sebastian Greenway, Leeanne Grigg, Winita Hardikar, Tim Hornung, et al.
Journal article | 2020 | Heart, Lung and Circulation
The Fontan circulation describes the circulatory state resulting from an operation in congenital heart disease where systemic veno..
A multi-national trial of a direct oral anticoagulant in children with cardiac disease: Design and rationale of the Safety of ApiXaban On Pediatric Heart disease On the preventioN of Embolism (SAXOPHONE) study
R Mark Payne, Kristin M Burns, Andrew C Glatz, Danshi Li, Xiaodong Li, Paul Monagle, Jane W Newburger, Elizabeth A Swan, Olivia Wheaton, Christoph Male
Journal article | 2019 | American Heart Journal
Anticoagulation in children is problematic for multiple reasons. Currently used anticoagulants have significant disadvantages and ..
Bodyweight-adjusted rivaroxaban for children with venous thromboembolism (EINSTEIN-Jr): results from three multicentre, single-arm, phase 2 studies
Paul Monagle, Anthonie WA Lensing, Kirstin Thelen, Ida Martinelli, Christoph Male, Amparo Santamaria, Elena Samochatova, Riten Kumar, Susanne Holzhauer, Paola Saracco, Paolo Simioni, Jeremy Robertson, Gernot Grangl, Jacqueline Halton, Phillip Connor, Guy Young, Angelo C Molinari, Ulrike Nowak-Goettl, Gili Kenet, Stefanie Kapsa, et al.
Journal article | 2019 | The Lancet Haematology
Reference Values for 30 Common Biochemistry Analytes Across 5 Different Analyzers in Neonates and Children 30 Days to 18 Years of Age
Monsurul Hoq, Susan Matthews, Vicky Karlaftis, Janet Burgess, Jessica Cowley, Susan Donath, John Carlin, Tina Yen, Vera Ignjatovic, Paul Monagle
Journal article | 2019 | Clinical Chemistry
Development and Validation of the Warfarin-Aspirin Bleeding Assessment Tool (WA-BAT) in Children.
Chantal Attard, Joanna Huang, Fiona Newall, Paul Monagle, Yves d'Udekem, Vera Ignjatovic
Journal article | 2019 | Journal of Pediatric Hematology/Oncology
Bleeding assessment tools (BATs) aim to screen and estimate bleeding risk in patients with inherited bleeding disorders. However, ..
A prospective, cross-sectional study to establish age-specific reference intervals for neonates and children in the setting of clinical biochemistry, immunology and haematology: the HAPPI Kids study protocol
Monsurul Hoq, Vicky Karlaftis, Susan Mathews, Janet Burgess, Susan M Donath, John Carlin, Paul Monagle, Vera Ignjatovic
Journal article | 2019 | BMJ Open
Motor function daily living skills 5 years after paediatric arterial ischaemic stroke: a prospective longitudinal study
Anna N Cooper, Vicki Anderson, Mardee Greenham, Stephen Hearps, Rod W Hunt, Mark T Mackay, Michael Ditchfield, Lee Coleman, Paul Monagle, Anne L Gordon
Journal article | 2019 | Developmental Medicine & Child Neurology
Australian Clinical Consensus Guideline: The diagnosis and acute management of childhood stroke
Tanya L Medley, Christina Miteff, Ian Andrews, Tyson Ware, Michael Cheung, Paul Monagle, Simone Mandelstam, Alison Wray, Clair Pridmore, Christopher Troedson, Russell C Dale, Michael Fahey, Adriane Sinclair, Peter Walsh, Belinda Stojanovski, Mark T MacKay
Journal article | 2019 | International Journal of Stroke
Bleeding and thrombotic events occur early in children on durable ventricular assist devices
Joanna Y Huang, Vera Ignjatovic, Bennett J Sheridan, Jacob Mathew, Yves D'Udekem, Johann Brink, Rebecca Barton, Gabrielle Callea, Dominique Morsman, Susan Donath, Stephen Opat, Paul Monagle
Journal article | 2019 | Thrombosis Research
Rivaroxaban versus standard anticoagulation for acute venous thromboembolism in childhood. Design of the EINSTEIN-Jr phase III study
Anthonie WA Lensing, Christoph Male, Guy Young, Dagmar Kubitza, Gili Kenet, M Patricia Massicotte, Anthony Chan, Angelo C Molinari, Ulrike Nowak-Goettl, Akos F Pap, Ivet Adalbo, William T Smith, Amy Mason, Kirstin Thelen, Scott D Berkowitz, Mark Crowther, Stephan Schmidt, Victoria Price, Martin H Prins, Paul Monagle
Journal article | 2018 | Thrombosis Journal
Exploratory evaluation of pharmacodynamics, pharmacokinetics and safety of rivaroxaban in children and adolescents: an EINSTEIN-Jr phase I study
Dagmar Kubitza, Stefan Willmann, Michael Becka, Kirstin Thelen, Guy Young, Leonardo R Brandao, Paul Monagle, Christoph Male, Anthony Chan, Gili Kennet, Ida Martinelli, Paola Saracco, Anthonie WA Lensing
Journal article | 2018 | Thrombosis Journal
American Society of Hematology 2018 Guidelines for management of venous thromboembolism: treatment of pediatric venous thromboembolism
Paul Monagle, Carlos A Cuello, Caitlin Augustine, Mariana Bonduel, Leonardo R Brandao, Tammy Capman, Anthony KC Chan, Sheila Hanson, Christoph Male, Joerg Meerpohl, Fiona Newall, Sarah H O'Brien, Leslie Raffini, Heleen van Ommen, John Wiernikowski, Suzan Williams, Meha Bhatt, John J Riva, Yetiani Roldan, Nicole Schwab, et al.
Journal article | 2018 | Blood Advances
Clinical presentation and therapeutic management of venous thrombosis in young children: a retrospective analysis
Anthony Chan, Anthonie WA Lensing, Dagmar Kubitza, Grahaem Brown, Dolores Elorza, Marta Ybarra, Jacqueline Halton, Sebastian Grunt, Gili Kenet, Damien Bonnet, Amparo Santamaria, Paola Saracco, Tina Biss, Francesco Climent, Philip Connor, Joseph Palumbo, Kirstin Thelen, William T Smith, Amy Mason, Ivet Adalbo, et al.
Journal article | 2018 | Thrombosis Journal
Treatment and secondary prophylaxis with ethanol lock therapy for central line-associated bloodstream infection in paediatric cancer: a randomised, double-blind, controlled trial
Joshua Wolf, Tom G Connell, Kim J Allison, Li Tang, Julie Richardson, Kristen Branum, Eloise Borello, Jeffrey E Rubnitz, Aditya H Gaur, Hana Hakim, Yin Su, Sara M Federico, Francoise Mechinaud, Randall T Hayden, Paul Monagle, Leon J Worth, Nigel Curtis, Patricia M Flynn
Journal article | 2018 | The Lancet Infectious Diseases
Identifying low-grade cellular rejection after heart transplantation in children by using gene expression profiling
Annie Xin, Melissa GY Lee, Yifang Hu, Vera Ignjatovic, William Y Shi, Anne Shipp, Slavica Praporski, Axel Kallies, Robert G Weintraub, Paul T Monagle, Gordon K Smyth, Igor E Konstantinov
Journal article | 2018 | Physiological Genomics
Expression of Biglycan in First Trimester Chorionic Villous Sampling Placental Samples and Altered Function in Telomerase-Immortalized Microvascular Endothelial Cells
Amy Chui, Tilini Gunatillake, Shaun P Brennecke, Vera Ignjatovic, Paul T Monagle, John M Whitelock, Dagmar E van Zanten, Jasper Eijsink, Yao Wang, James Deane, Anthony J Borg, Janet Stevenson, Jan Jaap Erwich, Joanne M Said, Padma Murthi
Journal article | 2017 | Arteriosclerosis, Thrombosis, and Vascular Biology
Differences in the mechanism of blood clot formation and nanostructure in infants and children compared with adults
Vera Ignjatovic, Leonie Pelkmans, Hilde Kelchtermans, Raed Al Dieri, Coen Hemker, Romy Kremers, Saartje Bloemen, Vasiliki Karlaftis, Chantal Attarda, Bas de Laat, Paul Monagle
Journal article | 2015 | Thrombosis Research
Monitoring Central Venous Catheter Resistance to Predict Imminent Occlusion: A Prospective Pilot Study
Joshua Wolf, Li Tang, Jeffrey E Rubnitz, Rachel C Brennan, David R Shook, Dennis C Stokes, Paul Monagle, Nigel Curtis, Leon J Worth, Kim Allison, Yilun Sun, Patricia M Flynn
Journal article | 2015 | PLOS ONE
Remote Ischemic Preconditioning (RIPC) Modifies the Plasma Proteome in Children Undergoing Repair of Tetralogy of Fallot: A Randomized Controlled Trial
Michele Hepponstall, Vera Ignjatovic, Steve Binos, Chantal Attard, Vasiliki Karlaftis, Yves d'Udekem, Paul Monagle, Igor E Konstantinov
Journal article | 2015 | PLOS ONE
Challenges and Priorities for Research A Report From the National Heart, Lung, and Blood Institute (NHLBI)/National Institutes of Health (NIH) Working Group on Thrombosis in Pediatric Cardiology and Congenital Heart Disease
Brian W McCrindle, Jennifer S Li, Cedric Manlhiot, James S Tweddell, Therese M Giglia, M Patricia Massicotte, Paul Monagle, Rajesh Krishnamurthy, Kenneth W Mahaffey, Alan D Michelson, Nicole Verdun, Christopher S Almond, Jane W Newburger, Leonardo R Brandao, Charles T Esmon, Marilyn J Manco-Johnson, Rebecca Ichord, Thomas L Ortel, Anthony K Chan, Ron Portman, et al.
Journal article | 2014 | Circulation
Vintage venoms: Proteomic and pharmacological stability of snake venoms stored for up to eight decades
Clemence Jesupret, Kate Baumann, Timothy NW Jackson, Syed Abid Ali, Daryl C Yang, Laura Greisman, Larissa Kern, Jessica Steuten, Mandokht Jouiaei, Nicholas R Casewell, Eivind AB Undheim, Ivan Koludarav, Jordan Debono, Dolyce HW Low, Sarah Rossi, Nadya Panagides, Kelly Winter, Vera Ignjatovic, Robyn Summerhayes, Alun Jones, et al.
Journal article | 2014 | Journal of Proteomics
Subcutaneous protein C concentrate in the management of severe protein C deficiency - experience from 12 centres
Adrian Minford, Wolfgang Behnisch, Paul Brons, Michele David, Natividad Gomez Gomez, Hans-Joerg Hertfelder, Anne Kruempel, Karin Kurnik, Mary Mathias, Antonio Molines Honrubia, Paul Monagle, Mary Morgan, Ulrike Nowak-Goettl, Martin Olivieri
Journal article | 2014 | British Journal of Haematology
Remote Ischemic Preconditioning Modifies the Plasma Proteome in Children Undergoing Repair of Tetralogy of Fallot: a Randomized Controlled Trial
Joanne M Hepponstall, Vera Ignjatovic, Steve Binos, Chantal Attard, Vasiliki Kariaftis, Yves d'Udekem, Paul Monagle, Igor Konstantinov
Conference Proceedings | 2013 | CIRCULATION
The economic costs of routine INR monitoring in infants and children - Examining point-of-care devices used within the home setting compared to traditional anticoagulation clinic monitoring
James R Gaw, Steven Crowley, Paul Monagle, Sophie Jones, Fiona Newall
Journal article | 2013 | Thrombosis Research
Altered Decorin Expression Leads to Disrupted Vascular Endothelial Cell Functions: A Potential Mechanism in the Pathogenesis of Human Fetal Growth Restriction
Amy KL Chui, Padma Murthi, Shaun P Brennecke, Vera Ignjatovic, Paul T Monagle, Joanne M Said
Conference Proceedings | 2013 | REPRODUCTIVE SCIENCES
Factors Associated With Thrombotic Complications After the Fontan Procedure A Secondary Analysis of a Multicenter, Randomized Trial of Primary Thromboprophylaxis for 2 Years After the Fontan Procedure
Brian W McCrindle, Cedric Manlhiot, Andrew Cochrane, Robin Roberts, Marina Hughes, Barbara Szechtman, Robert Weintraub, Maureen Andrew, Paul Monagle
Journal article | 2013 | Journal of the American College of Cardiology
Comparative effectiveness and safety of the novel oral anticoagulants: do the pivotal clinical trials point to a new paradigm?
AC Spyropoulos, NA Goldenberg, CM Kessler, J Kittelson, S Schulman, AGG Turpie, NR Cutler, WR Hiatt, JL Halperin
Journal article | 2012 | Journal of Thrombosis and Haemostasis
Individually tailored client-focused reports for ubiquitous devices: An experimental analysis
SP Smith, R Lederman, P Monagle, B Alzougool, L Naish, S Dreyfus
Conference Proceedings | 2012 | ACIS 2012 : Location, location, location : Proceedings of the 23rd Australasian Conference on Information Systems 2012
Standardization of post-thrombotic syndrome definition and outcome assessment following upper venous system thrombosis in pediatric practice.
S Revel-Vilk, LR Brandão, J Journeycake, NA Goldenberg, P Monagle, A Sharathkumar, AKC Chan, undefined Perinatal And Paediatric Haemostasis Subcommittee Of The Scientific And Standardization Committee Of The International Society On Thrombosis And Haemostasis
Journal article | 2012 | Journal of Thrombosis and Haemostasis
Definition of post-thrombotic syndrome following lower extremity deep venous thrombosis and standardization of outcome measurement in pediatric clinical investigations.
NA Goldenberg, LR Brandão, J Journeycake, SR Kahn, P Monagle, S Revel-vilk, A Sharathkumar, AKC Chan, undefined Perinatal And Paediatric Haemostasis Subcommittee Of The Scientific And Standardization Committee Of The International Society On Thrombosis And Haemostasis
Journal article | 2012 | Journal of Thrombosis and Haemostasis
Antithrombotic Therapy in Neonates and Children Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Paul Monagle, Anthony KC Chan, Neil A Goldenberg, Rebecca N Ichord, Janna M Journeycake, Ulrike Nowak-Goettl, Sara K Vesely
Journal article | 2012 | Chest
Impact of Persistent Antiphospholipid Antibodies on Risk of Incident Symptomatic Thromboembolism in Children: A Systematic Review and Meta-Analysis
Gili Kenet, Sofia Aronis, Yackov Berkun, Mariana Bonduel, Anthony Chan, Neil A Goldenberg, Susanne Holzhauer, Alfonso Iorio, Janna Journeycake, Ralf Junker, Christoph Male, Marilyn Manco-Johnson, Patti Massicotte, Rolf Mesters, Paul Monagle, Heleen van Ommen, Leslie Rafini, Paolo Simioni, Guy Young, Ulrike Nowak-Goettl
Journal article | 2011 | Seminars in Thrombosis and Hemostasis
A Multicenter, Randomized Trial Comparing Heparin/Warfarin and Acetylsalicylic Acid as Primary Thromboprophylaxis for 2 Years After the Fontan Procedure in Children
Paul Monagle, Andrew Cochrane, Robin Roberts, Cedric Manlhiot, Robert Weintraub, Barbara Szechtman, Marina Hughes, Maureen Andrew, Brian W McCrindle
Journal article | 2011 | Journal of the American College of Cardiology
Impact of Persistent Antiphospholipid Antibodies on Symptomatic Thromboembolism In Children: A Systematic Review & Meta-Analysis [Observational Studies]
Gili Kenet, Mariana Bonduel, Anthony Chan, Neil Goldenberg, Suzzane Holtzhauer, Alfonso Iorio, Janna M Journeycake, Ralf Junker, Christoph Male, Mary Patricia Massicotte, Rolf M Mesters, Paul Monagle, Heleen Van Ommen, Leslie Raffini, Paolo Simioni, Guy Young, Ulrike Nowak-Gottl
Conference Proceedings | 2010 | BLOOD
Evaluation of a Post-operative Thrombin Inhibitor Replacement Protocol to reduce Haemorrhagic and Thrombotic Complications after Paediatric Liver Transplantation
Winita Hardikar, Ujjal Poddar, Janis Chamberlain, Sharon Teo, Rukhmi Bhat, Bob Jones, Vera Ignjatovic, Janine Campbell, Fiona Newall, Paul Monagle
Journal article | 2010 | Thrombosis Research
Altered reference ranges for protein C and protein S during early pregnancy: Implications for the diagnosis of protein C and protein S deficiency during pregnancy
Joanne M Said, Vera Ignjatovic, Paul T Monagle, Susan P Walker, John R Higgins, Shaun P Brennecke
Journal article | 2010 | Thrombosis and Haemostasis
Impact of Thrombophilia on Risk of Arterial Ischemic Stroke or Cerebral Sinovenous Thrombosis in Neonates and Children A Systematic Review and Meta-Analysis of Observational Studies
Gili Kenet, Lisa K Luetkhoff, Manuela Albisetti, Timothy Bernard, Mariana Bonduel, Leonardo Brandao, Stephane Chabrier, Anthony Chan, Gabrielle deVeber, Barbara Fiedler, Heather J Fullerton, Neil A Goldenberg, Eric Grabowski, Gudrun Guenther, Christine Heller, Susanne Holzhauer, Alfonso Iorio, Janna Journeycake, Ralf Junker, Fenella J Kirkham, et al.
Journal article | 2010 | Circulation
Occlusive aortic arch thrombus in a preterm neonate.
Johny Vakayil Francis, Paul Monagle, Sarah Hope, Arvind Sehgal
Journal article | 2010 | Pediatric Critical Care Medicine
OBJECTIVE: To present the case of an extremely preterm infant with occlusive aortic arch clot managed with low-risk therapy. DATA ..
Impact of Thrombophilia On Arterial Ischemic Stroke or Cerebral Venous Sinus Thromboses in Children: A Systematic Review & Meta-Analysis of Observational Studies
Lisa K Luetkhoff, Manuela Albisetti, Timothy J Bernard, Mariana Bonduel, Leonardo R Brandao, Stephanie Chabrier, Anthony Chan, Barbara Fiedler, Heather J Fullerton, Vijeja Ganesan, Neil A Goldenberg, Meredith Golomb, Eric F Grabowski, Christine Heller, Susanne Holzhauer, Alfonso Iorio, Janna Journeycake, Gili Kenet, Fenella J Kirkham, Karin Kurnik, et al.
Conference Proceedings | 2009 | BLOOD
Factors Associated With Thrombotic Complications in the First 2 Years After the Fontan Procedure: A Multicentre Prospective Study
Brian W McCrindle, Andrew Cochrane, Robin Roberts, Barbara Szechtman, Michael Gent, Cedric Manlhiot, Robert Weintraub, Maureen Andrew, Paul Monagle
Conference Proceedings | 2009 | CIRCULATION
Point-of-care monitoring of oral anticoagulation therapy in children Comparison of the CoaguChek XS (R) system with venous INR and venous INR using an International Reference Thromboplastin preparation (rTF/95)
Anthea Greenway, Vera Ignjatovic, Robyn Summerhayes, Fiona Newalll, Janet Burgess, Lydia DeRosa, Paul Monagle
Journal article | 2009 | Thrombosis and Haemostasis
The prevalence of inherited thrombophilic polymorphisms in an asymptomatic Australian antenatal population
Joanne M Said, Shaun P Brennecke, Eric K Moses, Susan P Walker, Paul T Monagle, Janine Campbell, Valerie J Bryant, Anthony J Borg, John R Higgins
Journal article | 2008 | Australian and New Zealand Journal of Obstetrics and Gynaecology
A Multicentre Randomized Trial Comparing Heparin/warfarin Versus Aspirin As Primary Thromboprophylaxis For Two Years After Fontan Procedure In Children
Paul Monagle, Andrew Cochrane, Robin Roberts, Barbara Szechtman, Michael Gent, Maureen Andrew, Brian McCrindle
Conference Proceedings | 2008 | CIRCULATION
Impact of inherited thrombophilia on venous thromboembolism in children - A systematic review and meta-analysis of observational studies
Guy Young, Manuela Albisetti, Mariana Bonduel, Leonardo Brandao, Anthony Chan, Frauke Friedrichs, Neil A Goldenberg, Eric Grabowski, Christine Heller, Janna Journeycake, Gili Kenet, Anne Kruempel, Karin Kurnik, Aaron Lubetsky, Christoph Male, Marilyn Manco-Johnson, Prasad Mathew, Paul Monagle, Heleen van Ommen, Paolo Simioni, et al.
Journal article | 2008 | Circulation
Estimation of transient increases in bleeding risk associated with physical activity in children with haemophilia.
Carolyn R Broderick, Robert D Herbert, Jane Latimer, Chris Barnes, Julie A Curtin, Paul Monagle
Journal article | 2008 | BMC Blood Disorders
BACKGROUND: Although it is widely appreciated that vigorous physical activity can increase the risk of bleeding episodes in childr..
Monitoring unfractionated heparin (UFH) therapy: Which anti factor Xa assay is appropriate?
Vera Ignjatovic, Robyn Summerhayes, Andrew Gan, Jenny Than, Anthony Chan, Andrew Cochrane, Martin Bennett, Stephen Horton, Frank Shann, Geoff Lane, Maree Ross-Smith, Paul Monagle
Journal article | 2007 | Thrombosis Research
Antithrombotic therapy in children: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy.
Paul Monagle, Anthony Chan, Patti Massicotte, Elizabeth Chalmers, Alan D Michelson
Journal article | 2004 | Chest
This article about antithrombotic therapy in children is part of the 7th American College of Chest Physicians Conference on Antith..
Thromboembolic problems after the Fontan operation.
Paul Monagle, Tom R Karl
Journal article | 2002 | Pediatric Cardiac Surgery Annual of the Seminars in Thoracic and Cardiovascular Surgery
One of the major causes of morbidity and mortality after the Fontan operation is thromboembolic events (TE). To assess the current..
Outcome of pediatric thromboembolic disease: A report from the Canadian Childhood Thrombophilia Registry
P Monagle, M Adams, M Mahoney, K Ali, D Barnard, M Bernstein, L Brisson, M David, S Desai, MF Scully, J Halton, S Israels, L Jardine, M Leaker, P McCusker, M Silva, J Wu, R Anderson, M Andrew, MP Massicotte
Journal article | 2000 | Pediatric Research
Homozygous protein C deficiency: description of a new mutation and successful treatment with low molecular weight heparin.
P Monagle, M Andrew, J Halton, R Marlar, L Jardine, P Vegh, M Johnston, C Webber, MP Massicotte
Journal article | 1998 | Thrombosis and Haemostasis
We present a kindred with a new mutation of the protein C gene, in which the proband had an unusual clinical presentation. The rel..
Displaying the 2 most recent news articles by Paul Monagle.
Honours, Awards and Fellowships
Outstanding Research Award in Paediatric Cardiology
Gold Medal for services to children
Travelling scholarship awarded for training program with Dr Maureen Andrew, McMaster University, Canada
Medical student elective in Paediatrics, Solomon Islands
Medical student elective in paediatrics, Solomon Islands
FCCP - Fellow of the College of Chest Physicians
FRCPA - Fellow of the Royal College of Pathologists, Australia
FRACP - Fellow of the Royal Australasian College of Physicians
Professor In Paediatrics
Paediatrics Royal Children'S Hospital
AHCDO - Australian Haemophilia Centre Directors' Organisation
ISTH - International Society Haemostasis and Thrombosis
ASH - American Society for Hematology
SCT - Society for Clinical Trials
ASHT - Australiasian Society of Haemostasis and Thrombosis
HSA - Haematology Society of Australia
ASBT - Australasian Society of Blood Transfusion
Doctor of Medicine
Masters of Science (Health Research Methodology)
Bachelor of Medicine & Bachelor of Surgery