Orla McNally

Shifting incidence and survival of epithelial ovarian cancer (1995-2014): A SurvMark-2 study.

Citadel J Cabasag, Melina Arnold, Mark Rutherford, Jacques Ferlay, Aude Bardot, Eileen Morgan, John Butler, Dianne L O'Connell, Gregg Nelson, Claus Høgdall, Tine Schnack, Anna Gavin, Mark Elwood, Louise Hanna, Charlie Gourley, Prithwish De, Nathalie Saint-Jacques, Lina Steinrud Mørch, Ryan R Woods, Alon D Altman, et al.

Journal article  |  2023  |  Int J Cancer

The aim of the study is to provide a comprehensive assessment of incidence and survival trends of epithelial ovarian cancer (EOC) ..

Utility of risk of malignancy indices to predict ovarian malignancy in children and adolescents

Yasmin Jayasinghe, EA Blok, I Putri, JA How, O McNally, P Rao, J Marino, SR Grover, Y Jayasinghe

Journal article  |  2023  |  Journal of Pediatric and Adolescent Gynecology

Multiomic analysis of homologous recombination-deficient end-stage high-grade serous ovarian cancer.

Nikki L Burdett, Madelynne O Willis, Kathryn Alsop, Allison L Hunt, Ahwan Pandey, Phineas T Hamilton, Tamara Abulez, Xuan Liu, Therese Hoang, Stuart Craig, Sian Fereday, Joy Hendley, Dale W Garsed, Katy Milne, Shreena Kalaria, Ashley Marshall, Brian L Hood, Katlin N Wilson, Kelly A Conrads, Kathleen I Pishas, et al.

Journal article  |  2023  |  Nat Genet

High-grade serous ovarian cancer (HGSC) is frequently characterized by homologous recombination (HR) DNA repair deficiency and, wh..

Prognostic significance of FIGO 2018 staging of loco-regionally advanced cervical cancer (LRACC) with the use of MRI and PET and implications for treatment selection.

Ming Yin Lin, Linda Mileshkin, Orla McNally, Srinivas Kondalsamy-Chennakesavan, Kailash Narayan

Journal article  |  2023  |  Gynecol Oncol

INTRODUCTION: The FIGO 2018 staging of cervix cancer recognizes a total of 11 categories of loco-regionally advanced cervix cancer..

Combining TNFR2-Expressing Tregs and IL-6 as Superior Diagnostic Biomarkers for High-Grade Serous Ovarian Cancer Masses.

Nirmala Chandralega Kampan, Apriliana Ellya Ratna Kartikasari, Cyril Deceneux, Mutsa Tatenda Madondo, Orla M McNally, Katie Louise Flanagan, Norhaslinda A Aziz, Andrew N Stephens, John Reynolds, Michael A Quinn, Magdalena Plebanski

Journal article  |  2023  |  Cancers (Basel)

We hypothesised that the inclusion of immunosuppressive and inflammatory biomarkers in HGSOC patients would improve the sensitivit..

Pediatric, adolescent, and young adult breast and reproductive tumors.

Courtney J Harris, Erin E Rowell, Yasmin Jayasinghe, Carrye Cost, Krista J Childress, Natasha N Frederick, Orla McNally, Leslie Appiah, Antoinette Anazodo

Journal article  |  2022  |  Pediatr Blood Cancer

Tumors of the breast and reproductive organs that occur in children, adolescents, and young adults (AYA) have different biological..

Epithelial-to-Mesenchymal Transition Supports Ovarian Carcinosarcoma Tumorigenesis and Confers Sensitivity to Microtubule Targeting with Eribulin

Gwo Yaw Ho, Elizabeth L Kyran, Justin Bedo, Matthew J Wakefield, Darren P Ennis, Hasan B Mirza, Cassandra J Vandenberg, Elizabeth Lieschke, Andrew Farrell, Anthony Hadla, Ratana Lim, Genevieve Dall, James E Vince, Ngee Kiat Chua, Olga Kondrashova, Rosanna Upstill-Goddard, Ulla-Maja Bailey, Suzanne Dowson, Patricia Roxburgh, Rosalind M Glasspool, et al.

Journal article  |  2022  |  CANCER RESEARCH

UNLABELLED: Ovarian carcinosarcoma (OCS) is an aggressive and rare tumor type with limited treatment options. OCS is hypothesized ..

The genomic and immune landscape of long-term survivors of high-grade serous ovarian cancer

Dale W Garsed, Ahwan Pandey, Sian Fereday, Catherine J Kennedy, Kazuaki Takahashi, Kathryn Alsop, Phineas T Hamilton, Joy Hendley, Yoke-Eng Chiew, Nadia Traficante, Pamela Provan, Dinuka Ariyaratne, George Au-Yeung, Nicholas W Bateman, Leanne Bowes, Alison Brand, Elizabeth L Christie, Julie M Cunningham, Michael Friedlander, Bronwyn Grout, et al.

Journal article  |  2022  |  NATURE GENETICS

Fewer than half of all patients with advanced-stage high-grade serous ovarian cancers (HGSCs) survive more than five years after d..

EP082/#839 ISO-prognostic clusters in advanced cervix cancer treated with curative intent

Kailash Narayan, Ming-Yin Lin, Linda Mileshkin, Srinivas Kondalsamy-Chennakesavan, Orla Mcnally

Conference Proceedings  |  2022  |  E-Posters

The changing role for extended resections in an era of advanced radiotherapy techniques and novel therapies in gynaecological malignancy.

RD McBain, MFG McGauran, KH Tran, G Au-Yeung, PYL Khaw, OM McNally

Journal article  |  2022  |  Eur J Surg Oncol

Pelvic exenteration, first described in 1948 and subsequently refined, may be offered as a last hope of cure to patients with recu..