Wesley Thevathasan

Targeting the centromedian thalamic nucleus for deep brain stimulation

Aaron EL Warren, Linda J Dalic, Wesley Thevathasan, Annie Roten, Kristian J Bulluss, John Archer

Journal article  |  2020  |  Journal of Neurology, Neurosurgery & Psychiatry

OBJECTIVES: Deep brain stimulation (DBS) of the centromedian thalamic nucleus (CM) is an emerging treatment for multiple brain dis..

Tailoring Subthalamic Nucleus Deep Brain Stimulation for Parkinson's Disease Using Evoked Resonant Neural Activity

Wesley Thevathasan, Nicholas C Sinclair, Kristian J Bulluss, Hugh J McDermott

Journal article  |  2020  |  Frontiers in Human Neuroscience

Deep brain stimulation for Parkinson's disease modulates high-frequency evoked and spontaneous neural activity

Nicholas C Sinclair, Hugh J McDermott, James B Fallon, Thushara Perera, Peter Brown, Kristian J Bulluss, Wesley Thevathasan

Journal article  |  2019  |  Neurobiology of Disease

Deep brain stimulation is an established therapy for Parkinson's disease; however, its effectiveness is hindered by limited unders..

What is the therapeutic mechanism of pedunculopontine nucleus stimulation in Parkinson's disease?

Wesley Thevathasan, Elena Moro

Journal article  |  2019  |  Neurobiology of Disease

On the neural basis of deep brain stimulation evoked resonant activity

Nicholas C Sinclair, James B Fallon, Kristian J Bulluss, Wesley Thevathasan, Hugh J McDermott

Journal article  |  2019  |  Biomedical Physics & Engineering Express

SUBTHALAMIC NUCLEUS DEEP BRAIN STIMULATION EVOKED RESONANT NEURAL ACTIVITY PREDICTS CLINICAL RESPONSE TO DBS

San San Xu, Nicholas C Sinclair, Kristian J Bulluss, Thushara Perera, Wee-Lih Lee, Hugh J McDermott, Wesley Theathasan

Conference Proceedings  |  2019  |  Journal of Neurology, Neurosurgery & Psychiatry

An Instrumented Pull Test to Characterize Postural Responses

Joy Tan, Wesley Thevathasan, Jennifer McGinley, Peter Brown, Thushara Perera

Journal article  |  2019  |  Journal of Visualized Experiments

Alternate Subthalamic Nucleus Deep Brain Stimulation Parameters to Manage Motor Symptoms of Parkinson's Disease: Systematic Review and Meta-analysis

Zachary J Conway, Peter A Silburn, Wesley Thevathasan, Karen O' Maley, Geraldine A Naughton, Michael H Cole

Journal article  |  2019  |  Movement Disorders Clinical Practice

Neurophysiological analysis of the clinical pull test

Joy Lynn Tan, Thushara Perera, Jennifer L McGinley, Shivanthan Arthur Curtis Yohanandan, Peter Brown, Wesley Thevathasan

Journal article  |  2018  |  Journal of Neurophysiology

Balance control systems in Parkinson's disease and the impact of pedunculopontine area stimulation

Thushara Perera, Joy L Tan, Michael H Cole, Shivy AC Yohanandan, Paul Silberstein, Raymond Cook, Richard Peppard, Tipu Aziz, Terry Coyne, Peter Brown, Peter A Silburn, Wesley Thevathasan

Journal article  |  2018  |  Brain

Subthalamic nucleus deep brain stimulation evokes resonant neural activity

Nicholas C Sinclair, Hugh J McDermott, Kristian J Bulluss, James B Fallon, Thushara Perera, San San Xu, Peter Brown, Wesley Thevathasan

Journal article  |  2018  |  Annals of Neurology

Association between hemorrhagic transformation after endovascular therapy and poststroke seizures

Arthur Thevathasan, Jillian Naylor, Leonid Churilov, Peter J Mitchell, Richard J Dowling, Bernard Yan, Patrick Kwan

Journal article  |  2018  |  Epilepsia

Pedunculopontine Nucleus Deep Brain Stimulation in Parkinson's Disease: A Clinical Review

Wesley Thevathasan, Bettina Debu, Tipu Aziz, Bastiaan R Bloem, Christian Blahak, Christopher Butson, Virginie Czernecki, Thomas Foltynie, Valerie Fraix, David Grabli, Carole Joint, Andres M Lozano, Michael S Okun, Jill Ostrem, Nicola Pavese, Christoph Schrader, Chun-Hwei Tai, Joachim K Krauss, Elena Moro

Journal article  |  2018  |  Movement Disorders

Functional Connectivity of the Pedunculopontine Nucleus and Surrounding Region in Parkinson's Disease

Ashwani Jha, Vladimir Litvak, Samu Taulu, Wesley Thevathasan, Jonathan A Hyam, Tom Foltynie, Patricia Limousin, Marko Bogdanovic, Ludvic Zrinzo, Alexander L Green, Tipu Z Aziz, Karl Friston, Peter Brown

Journal article  |  2017  |  Cerebral Cortex

Clinical validation of a precision electromagnetic tremor measurement system in participants receiving deep brain stimulation for essential tremor

Thushara Perera, Shivanthan AC Yohanandan, Wesley Thevathasan, Mary Jones, Richard Peppard, Andrew H Evans, Joy L Tan, Colette M McKay, Hugh J McDermott

Journal article  |  2016  |  Physiological Measurement

Understanding the human pedunculopontine nucleus in Parkinson's disease

Anders Fytagoridis, Peter A Silburn, Terry J Coyne, Wesley Thevathasan

Journal article  |  2016  |  Journal of Neural Transmission

Pedunculopontine Nucleus Region Deep Brain Stimulation in Parkinson Disease: Surgical Techniques, Side Effects, and Postoperative Imaging

Clement Hamani, Andres M Lozano, Paolo AM Mazzone, Elena Moro, William Hutchison, Peter A Silburn, Ludvic Zrinzo, Mesbah Alam, Laurent Goetz, Erlick Pereira, Anand Rughani, Wesley Thevathasan, Tipu Aziz, Bastiaan R Bloem, Peter Brown, Stephan Chabardes, Terry Coyne, Kelly Foote, Edgar Garcia-Rill, Etienne C Hirsch, et al.

Journal article  |  2016  |  Stereotactic and Functional Neurosurgery

Pedunculopontine Nucleus Region Deep Brain Stimulation in Parkinson Disease: Surgical Anatomy and Terminology

Clement Hamani, Tipu Aziz, Bastiaan R Bloem, Peter Brown, Stephan Chabardes, Terry Coyne, Kelly Foote, Edgar Garcia-Rill, Etienne C Hirsch, Andres M Lozano, Paolo AM Mazzone, Michael S Okun, William Hutchison, Peter Silburn, Ludvic Zrinzo, Mesbah Alam, Laurent Goetz, Erlick Pereira, Anand Rughani, Wesley Thevathasan, et al.

Journal article  |  2016  |  Stereotactic and Functional Neurosurgery

Tremor Reduction by Deep Brain Stimulation Is Associated With Gamma Power Suppression in Parkinson's Disease

Martijn Beudel, Simon Little, Alek Pogosyan, Keyoumars Ashkan, Thomas Foltynie, Patricia Limousin, Ludvic Zrinzo, Marwan Hariz, Marko Bogdanovic, Binith Cheeran, Alexander L Green, Tipu Aziz, Wesley Thevathasan, Peter Brown

Journal article  |  2015  |  Neuromodulation: Technology at the Neural Interface

Where and what is the PPN and what is its role in locomotion?

Francois Windels, Wesley Thevathasan, Peter Silburn, Pankaj Sah

Journal article  |  2015  |  Brain

PALLIDAL SOMATOTOPY SUGGESTED BY DEEP BRAIN STIMULATION IN A PATIENT WITH DYSTONIA

Carole Joint, Wesley Thevathasan, Alex L Green, Tipu Aziz

Journal article  |  2013  |  Neurology

A spatiotemporal analysis of gait freezing and the impact of pedunculopontine nucleus stimulation

Wesley Thevathasan, Michael H Cole, Cara L Graepel, Jonathan A Hyam, Ned Jenkinson, John-Stuart Brittain, Terry J Coyne, Peter A Silburn, Tipu Z Aziz, Graham Kerr, Peter Brown

Journal article  |  2012  |  Brain

Alpha oscillations in the pedunculopontine nucleus correlate with gait performance in parkinsonism

Wesley Thevathasan, Alek Pogosyan, Jonathan A Hyam, Ned Jenkinson, Tom Foltynie, Patricia Limousin, Marko Bogdanovic, Ludvic Zrinzo, Alexander L Green, Tipu Z Aziz, Peter Brown

Journal article  |  2012  |  Brain

Pedunculopontine Nucleus Stimulation Improves Gait Freezing in Parkinson Disease

Wesley Thevathasan, Terry J Coyne, Jonathan A Hyam, Graham Kerr, Ned Jenkinson, Tipu Z Aziz, Peter A Silburn

Journal article  |  2011  |  Neurosurgery

A block to pre-prepared movement in gait freezing, relieved by pedunculopontine nucleus stimulation

Wesley Thevathasan, Alek Pogosyan, Jonathan A Hyam, Ned Jenkinson, Marko Bogdanovic, Terry J Coyne, Peter A Silburn, Tipu Z Aziz, Peter Brown

Journal article  |  2011  |  Brain

Deep brain stimulation can suppress pathological synchronisation in parkinsonian patients

A Eusebio, W Thevathasan, L Doyle Gaynor, A Pogosyan, E Bye, T Foltynie, L Zrinzo, K Ashkan, T Aziz, P Brown

Journal article  |  2011  |  Journal of Neurology, Neurosurgery and Psychiatry

Permanent tremor reduction during thalamic stimulation in multiple sclerosis

Wesley Thevathasan, Patrick Schweder, Carole Joint, Nicola Ray, Pieter Pretorius, Ralph Gregory, Tipu Aziz

Journal article  |  2011  |  Journal of Neurology, Neurosurgery and Psychiatry

Oculopharyngodistal myopathy - A possible association with cardiomyopathy

Wesley Thevathasan, Waney Squier, David H MacIver, David A Hilton, Edward Fathers, David Hilton-Jones

Journal article  |  2011  |  Neuromuscular Disorders

THALAMOTOMY FOR POSTAPOPLECTIC HEMIBALLISTIC CHOREA IN OLDER ADULTS

Arnar Astradsson, Patrick Schweder, Carole Joint, Beth Forrow, Wesley Thevathasan, Erlick AC Pereira, Alexander L Green, Tipu Z Aziz

Journal article  |  2010  |  Journal of the American Geriatrics Society

Reply from the authors

W Thevathasan, P Brown

Journal article  |  2010  |  Neurology

Oculopharyngodistal myopathy - a possible association with cardiomyopathy

D Hilton-Jones, W Thevathasan, W Squier, D Maclver, D Hilton, E Fathers

Conference Proceedings  |  2010  |  Neuromuscular Disorders

The impact of low-frequency stimulation of the pedunculopontine nucleus region on reaction time in parkinsonism

Wesley Thevathasan, Peter A Silburn, Helen Brooker, Terry J Coyne, Sadaquate Khan, Steven S Gill, Tipu Z Aziz, Peter Brown

Journal article  |  2010  |  Journal of Neurology, Neurosurgery and Psychiatry

Predicting falls in Parkinson disease A step in the right direction

Wesley Thevathasan, Tipu Aziz

Journal article  |  2010  |  Neurology

SPINAL CORD STIMULATION FAILED TO RELIEVE AKINESIA OR RESTORE LOCOMOTION IN PARKINSON DISEASE

W Thevathasan, P Mazzone, A Jha, A Djamshidian, M Dileone, V Di Lazzaro, P Brown

Journal article  |  2010  |  Neurology

Deep brain stimulation for movement disorders.

Wesley Thevathasan, Ralph Gregory

Journal article  |  2010  |  Practical Neurology

Deep brain stimulation is now considered a routine treatment option for selected patients with advanced Parkinson's disease, prima..

Involvement of the subthalamic nucleus in engagement with behaviourally relevant stimuli

Paul Sauleau, Alexandre Eusebio, Wesley Thevathasan, Kielan Yarrow, Alek Pogosyan, Ludvic Zrinzo, Keyoumars Ashkan, Tipu Aziz, Wim Vandenberghe, Bart Nuttin, Peter Brown

Journal article  |  2009  |  European Journal of Neuroscience

Vasogenic oedema with no mass lesion Cerebral amyloid angiopathy (CAA)

Shen-Yang Lim, A Wesley Thevathasan, Michael Gonzales, Peter J Mitchell, Andrew H Evans

Journal article  |  2008  |  Journal of Clinical Neuroscience

Serpentine tongue - A lingual dyskinesia

SHC Sheehy, T Lawrence, AW Thevathasan

Journal article  |  2008  |  Neurology

TEMPORAL ARTERITIS

A Wesley Thevathasan, Stephen M Davis

Book Chapter  |  2008