Troi Pediongco

Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection

Zhe Zhao, Huimeng Wang, Mai Shi, Tianyuan Zhu, Troi Pediongco, Xin Yi Lim, Bronwyn S Meehan, Adam G Nelson, David P Fairlie, Jeffrey YW Mak, Sidonia BG Eckle, Marcela de Lima Moreira, Carolin Tumpach, Michael Bramhall, Cameron G Williams, Hyun Jae Lee, Ashraful Haque, Maximilien Evrard, Jamie Rossjohn, James McCluskey, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

Mucosal-associated Invariant T (MAIT) cells are recognized for their antibacterial functions. The protective capacity of MAIT cell..

IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection

Huimeng Wang, Lars Kjer-Nielsen, Mai Shi, Criselle D'Souza, Troi J Pediongco, Hanwei Cao, Lyudmila Kostenko, Xin Yi Lim, Sidonia BG Eckle, Bronwyn S Meehan, Tianyuan Zhu, Bingjie Wang, Zhe Zhao, Jeffrey YW Mak, David P Fairlie, Michele WL Teng, Jamie Rossjohn, Di Yu, Barbara Fazekas de St Groth, George Lovrecz, et al.

Journal article  |  2019  |  SCIENCE IMMUNOLOGY

Mucosal-associated invariant T (MAIT) cells are activated in a TCR-dependent manner by antigens derived from the riboflavin synthe..

IL-23 co-stimulation drives antigen-specific MAIT cell activation and enables vaccination against bacterial infection

H Wang, L Kjer-Nielsen, M Shi, DC Souza, T Pediongco, H Cao, L Kostenko, X Lim, S Eckle, B Meeha, B Wang, T Zhu, J Mak, D Fairlie, M Teng, J Rossjohn, D Yu, B Groth, J McCluskey, R Strugnell, et al.

Conference Proceedings  |  2019  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Activation and In Vivo Evolution of the MAIT Cell Transcriptome in Mice and Humans Reveals Tissue Repair Functionality

Timothy SC Hinks, Emanuele Marchi, Maisha Jabeen, Moshe Olshansky, Ayako Kurioka, Troi J Pediongco, Bronwyn S Meehan, Lyudmila Kostenko, Stephen J Turner, Alexandra J Corbett, Zhenjun Chen, Paul Klenerman, James McCluskey

Journal article  |  2019  |  CELL REPORTS

Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells conserved across mammalian species, including m..

Characterization and Purification of Mouse Mucosal-Associated Invariant T (MAIT) Cells

Zhenjun Chen, Huimeng Wang, Criselle D'Souza, Hui-Fern Koay, Bronwyn Meehan, Zhe Zhao, Troi Pediongco, Mai Shi, Tianyuan Zhu, Bingjie Wang, Lars Kjer-Nielsen, Sidonia BG Eckle, Jamie Rossjohn, David P Fairlie, Dale I Godfrey, Richard A Strugnell, James McCluskey, Alexandra J Corbett

Journal article  |  2019  |  Current protocols in immunology

This unit describes the utility of various mouse models of infection and immunization for studying mucosal-associated invariant T ..

Activation and in vivo evolution of the MAIT cell transcriptome in mice and humans reveals diverse functionality

Timothy SC Hinks, Emanuele Marchi, Maisha Jabeen, Moshe Olshansky, Ayako Kurioka, Troi Pediongco, Bronwyn Meehan, Lyudmila Kostenko, Stephen Turner, Alexandra Corbett, Zhenjun Chen, Paul Klenerman, James McCluskey

Journal article  |  2018

Mucosal-associated invariant T (MAIT) cells are MR1-restricted innate-like T cells conserved across mammalian species, including m..

MAIT CELLS CONTRIBUTE TO A PROTECTIVE ANTIVIRAL INNATE RESPONSE TO INFLUENZA INFECTION

TSC Hinks, B van Wilgenburg, L Loh, TJ Pediongco, H Wang, M Shi, Z Zhao, M Koutsakos, S Nussing, S Sant, Z Wang, C D'Souza, CF Almeida, P Reading, AJ Corbett, J McCluskey, P Klenerman, K Kedzierska

Conference Proceedings  |  2018  |  THORAX

MAIT cells contribute to protection against lethal influenza infection in vivo

Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Xiaoxiao Jia, Catarina F Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn S Meehan, Axel Kallies, Dale I Godfrey, Patrick C Reading, et al.

Journal article  |  2018  |  NATURE COMMUNICATIONS

Mucosal associated invariant T (MAIT) cells are evolutionarily-conserved, innate-like lymphocytes which are abundant in human lung..

MAIT cells contribute to a protective antiviral innate response to influenza infection

Timothy Hinks, Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Catarina Almeida, Patrick Reading, Alexandra Corbett, James Mccluskey, Paul Klenerman, Katherine Kedzierska

Conference Proceedings  |  2018  |  EUROPEAN RESPIRATORY JOURNAL

MAIT cells protect against pulmonary Legionella longbeachae infection

Huimeng Wang, Criselle D'Souza, Xin Yi Lim, Lyudmila Kostenko, Troi J Pediongco, Sidonia BG Eckle, Bronwyn S Meehan, Mai Shi, Nancy Wang, Shihan Li, Ligong Liu, Jeffrey YW Mak, David P Fairlie, Yoichiro Iwakura, Jennifer M Gunnersen, Andrew W Stent, Dale I Godfrey, Jamie Rossjohn, Glen P Westall, Lars Kjer-Nielsen, et al.

Journal article  |  2018  |  NATURE COMMUNICATIONS

Mucosal associated invariant T (MAIT) cells recognise conserved microbial metabolites from riboflavin synthesis. Striking evolutio..