Lindsea Booth

Blunted diuretic and natriuretic responses to acute sodium loading early after catheter-based renal denervation in normotensive sheep

Zoe McArdle, Roberto B Pontes, Song T Yao, Yugeh R Lankadeva, Reetu R Singh, Sally G Hood, Markus P Schlaich, Clive N May, Lindsea C Booth

Journal article  |  2019  |  AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Catheter-based renal denervation (RDN) was introduced as a treatment for resistant hypertension. There remain critical questions r..

Renal perfusion, oxygenation, and sympathetic nerve activity during volatile or intravenous general anaesthesia in sheep

Naoya Iguchi, Junko Kosaka, Lindsea C Booth, Yoko Iguchi, Roger G Evans, Rinaldo Bellomo, Clive N May, Yugeesh R Lankadeva

Journal article  |  2019  |  BRITISH JOURNAL OF ANAESTHESIA

BACKGROUND: Global and intra-renal perfusion and oxygenation may be affected by the choice of anaesthetic. We compared the effects..

Sustained Decrease in Blood Pressure and Reduced Anatomical and Functional Reinnervation of Renal Nerves in Hypertensive Sheep 30 Months After Catheter-Based Renal Denervation

Reetu R Singh, Zoe M McArdle, Michael Iudica, Lawrence K Easton, Lindsea C Booth, Clive N May, Helena C Parkington, Paul Lombardo, Geoff A Head, Gavin Lambert, Karen M Moritz, Markus P Schlaich, Kate M Denton

Journal article  |  2019  |  HYPERTENSION

We examined whether renal denervation (RDN) reduced blood pressure (BP), improved glomerular filtration rate, albuminuria, and lef..

EFFECTS OF CLONIDINE ON THE CARDIOVASCULAR, RENAL, AND INFLAMMATORY RESPONSES TO EXPERIMENTAL BACTEREMIA

Paolo Calzavacca, Lindsea C Booth, Yugeesh R Lankadeva, Simon R Bailey, Louise M Burrell, Michael Bailey, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  SHOCK

INTRODUCTION: Supra-clinical doses of clonidine appear beneficial in experimental sepsis, but there is limited understanding of th..

Effects of Fluid Bolus Therapy on Renal Perfusion, Oxygenation, and Function in Early Experimental Septic Kidney Injury

Yugeesh R Lankadeva, Junko Kosaka, Naoya Iguchi, Roger G Evans, Lindsea C Booth, Rinaldo Bellomo, Clive N May

Journal article  |  2019  |  CRITICAL CARE MEDICINE

OBJECTIVES: To examine the effects of fluid bolus therapy on systemic hemodynamics, renal blood flow, intrarenal perfusion and oxy..

Alterations in regional kidney oxygenation during expansion of extracellular fluid volume in conscious healthy sheep

Yugeesh R Lankadeva, Roger G Evans, Junko Kosaka, Lindsea C Booth, Naoya Iguchi, Rinaldo Bellomo, Clive N May

Journal article  |  2018  |  AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Expansion of extracellular fluid volume with crystalloid solutions is a common medical intervention, but its effects on renal cort..

Increased cardiac sympathetic nerve activity in ovine heart failure is reduced by lesion of the area postrema, but not lamina terminalis

Yonis Abukar, Rohit Ramchandra, Sally G Hood, Michael J McKinley, Lindsea C Booth, Song T Yao, Clive N May

Journal article  |  2018  |  BASIC RESEARCH IN CARDIOLOGY

Increased cardiac sympathetic nerve activity (CSNA) is a key feature of heart failure (HF) and is associated with poor outcome. Th..

Catheter-Based Renal Denervation Exacerbates Blood Pressure Fall During Hemorrhage

Reetu R Singh, Varsha Sajeesh, Lindsea C Booth, Zoe McArdle, Clive N May, Geoffrey A Head, Karen M Moritz, Markus P Schlaich, Kate M Denton

Journal article  |  2017  |  JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

BACKGROUND: Clinical trials applying catheter-based radiofrequency renal denervation (RDN) demonstrated a favorable safety profile..

The role of the renal afferent and efferent nerve fibers in heart failure

Lindsea C Booth, Clive N May, Song T Yao

Journal article  |  2015  |  FRONTIERS IN PHYSIOLOGY

Renal nerves contain afferent, sensory and efferent, sympathetic nerve fibers. In heart failure (HF) there is an increase in renal..

Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure

Lindsea C Booth, Markus P Schlaich, Erika E Nishi, Song T Yao, Jianzhong Xu, Rohit Ramchandra, Gavin W Lambert, Clive N May

Journal article  |  2015  |  INTERNATIONAL JOURNAL OF CARDIOLOGY

OBJECTIVES: Sympathetic drive, especially to the heart, is elevated in heart failure and is strongly associated with poor outcome...