Amber Alsop

Mcl-1 and Bcl-x(L) sequestration of Bak confers differential resistance to BH3-only proteins

Colin Hockings, Amber E Alsop, Stephanie C Fennell, Erinna F Lee, W Douglas Fairlie, Grant Dewson, Ruth M Kluck

Journal article  |  2018  |  Cell Death & Differentiation

BAK alpha 6 permits activation by BH3-only proteins and homooligomerization via the canonical hydrophobic groove

Mark Xiang Li, Iris KL Tan, Stephen B Ma, Colin Hockings, Tobias Kratina, Michael A Dengler, Amber E Alsop, Ruth M Kluck, Grant Dewson

Journal article  |  2017  |  Proceedings of the National Academy of Sciences of the United States of America

Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization

Daniella Brasacchio, Amber E Alsop, Tahereh Noori, Mariam Lufti, Sweta Iyer, Kaylene J Simpson, Phillip I Bird, Ruth M Kluck, Ricky W Johnstone, Joseph A Trapani

Journal article  |  2017  |  Cell Death & Differentiation

Disordered clusters of Bak dimers rupture mitochondria during apoptosis

Rachel T Uren, Martin O'Hely, Sweta Iyer, Ray Bartolo, Melissa X Shi, Jason M Brouwer, Amber E Alsop, Grant Dewson, Ruth M Kluck

Journal article  |  2017  |  eLife

Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies

Sweta Iyer, Khatira Anwari, Amber E Alsop, Wai Shan Yuen, David CS Huang, John Carroll, Nicholas A Smith, Brian J Smith, Grant Dewson, Ruth M Kluck

Journal article  |  2016  |  NATURE COMMUNICATIONS

Dissociation of Bak alpha 1 helix from the core and latch domains is required for apoptosis

Amber E Alsop, Stephanie C Fennell, Ray C Bartolo, Iris KL Tan, Grant Dewson, Ruth M Kluck

Journal article  |  2015  |  Nature Communications

Fas ligand-mediated immune surveillance by T cells is essential for the control of spontaneous B cell lymphomas

Shoukat Afshar-Sterle, Dimitra Zotos, Nicholas J Bernard, Anna K Scherger, Lisa Roedling, Amber E Alsop, Jennifer Walker, Frederick Masson, Gabrielle T Belz, Lynn M Corcoran, Lorraine A O'Reilly, Andreas Strasser, Mark J Smyth, Ricky Johnstone, David M Tarlinton, Stephen L Nutt, Axel Kallies

Journal article  |  2014  |  Nature Medicine

Reconstruction of the ancestral marsupial karyotype from comparative gene maps

Janine E Deakin, Margaret L Delbridge, Edda Koina, Nerida Harley, Amber E Alsop, Chenwei Wang, Vidushi S Patel, Jennifer A Marshall Graves

Journal article  |  2013  |  BMC Evolutionary Biology

Cyclin E facilitates dysplastic hepatocytes to bypass G(1)/S checkpoint in hepatocarcinogenesis

Sharon Pok, Victoria Wen, Nicholas Shackel, Amber Alsop, Pawan Pyakurel, Aude Fahrer, Geoffrey C Farrell, Narci C Teoh

Journal article  |  2013  |  Journal of Gastroenterology and Hepatology

Bak apoptotic function is not directly regulated by phosphorylation

VH Tran, R Bartolo, D Westphal, A Alsop, G Dewson, RM Kluck

Journal article  |  2013  |  Cell Death and Disease