Giuseppe Infusini

Dynamic reconfiguration of pro-apoptotic BAK on membranes

Jarrod J Sandow, Iris Kl Tan, Alan S Huang, Shashank Masaldan, Jonathan P Bernardini, Ahmad Z Wardak, Richard W Birkinshaw, Robert L Ninnis, Ziyan Liu, Destiny Dalseno, Daisy Lio, Giuseppi Infusini, Peter E Czabotar, Andrew Webb, Grant Dewson

Journal article  |  2021  |  EMBO JOURNAL

BAK and BAX, the effectors of intrinsic apoptosis, each undergo major reconfiguration to an activated conformer that self-associat..

Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men

Liza O'Donnell, Diane Rebourcet, Laura F Dagley, Raouda Sgaier, Giuseppe Infusini, Peter J O'Shaughnessy, Frederic Chalmel, Daniela Fietz, Wolfgang Weidner, Julien MD Legrand, Robin M Hobbs, Robert McLachlan, Andrew Webb, Adrian Pilatz, Thorsten Diemer, Lee B Smith, Peter G Stanton

Journal article  |  2021  |  FASEB JOURNAL

Sperm develop from puberty in the seminiferous tubules, inside the blood-testis barrier to prevent their recognition as "non-self"..

Serum microRNA is a biomarker for post-operative monitoring in glioma

Andrew Morokoff, Jordan Jones, Hong Nguyen, Chenkai Ma, Arian Lasocki, Frank Gaillard, Iwan Bennett, Rod Luwor, Stanley Stylli, Lucia Paradiso, Rachel Koldej, Iddo Paldor, Ramyar Molania, Terence P Speed, Andrew Webb, Guiseppe Infusini, Jason Li, Charles Malpas, Tomas Kalincik, Katharine Drummond, et al.

Journal article  |  2020  |  JOURNAL OF NEURO-ONCOLOGY

PURPOSE: A circulating biomarker has potential to provide more accurate information for glioma progression post treatment, however..

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response

James G Bedford, Giuseppe Infusini, Laura F Dagley, Fernando Villalon-Letelier, Ming ZM Zheng, Vicki Bennett-Wood, Patrick C Reading, Linda M Wakim

Journal article  |  2020  |  FRONTIERS IN IMMUNOLOGY

Exosomes are extracellular vesicles secreted by cells that have an important biological function in intercellular communication by..

Universal Solid-Phase Protein Preparation (USP3) for Bottom-up and Top-down Proteomics

Laura F Dagley, Giuseppe Infusini, Rune H Larsen, Jarrod J Sandow, Andrew I Webb

Journal article  |  2019  |  JOURNAL OF PROTEOME RESEARCH

Selecting a sample preparation strategy for mass spectrometry-based proteomics is critical to the success of quantitative workflow..

Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair.

Jemma Evans, Giuseppe Infusini, Jacqui McGovern, Leila Cuttle, Andrew Webb, Thomas Nebl, Liz Milla, Roy Kimble, Margit Kempf, Christine J Andrews, David Leavesley, Lois A Salamonsen

Journal article  |  2019  |  FASEB J

Repair after damage is essential for tissue homeostasis. Postmenstrual endometrial repair is a cyclical manifestation of rapid, sc..

Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii

Michael J Coffey, Laura F Dagley, Simona Seizova, Eugene A Kapp, Giuseppe Infusini, David S Roos, Justin A Boddey, Andrew I Webb, Christopher J Tonkin

Journal article  |  2018  |  MBIO

Toxoplasma gondii infects approximately 30% of the world's population, causing disease primarily during pregnancy and in individua..

Idiopathic infertility in women is associated with distinct changes in proliferative phase uterine fluid proteins

Harriet C Fitzgerald, Jemma Evans, Nicholas Johnson, Giuseppe Infusini, Andrew Webb, Luk JR Rombauts, Beverley J Vollenhoven, Lois A Salamonsen, Tracey A Edgell

Journal article  |  2018  |  BIOLOGY OF REPRODUCTION

The regenerative, proliferative phase of a woman's menstrual cycle is a critical period which lays the foundation for the subseque..

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine

Jarrod J Sandow, Adam Rainczuk, Giuseppe Infusini, Ming Makanji, Maree Bilandzic, Amy L Wilson, Nicole Fairweather, Peter G Stanton, Daniel Garama, Daniel Gough, Thomas W Jobling, Andrew I Webb, Andrew N Stephens

Journal article  |  2018  |  PROTEOMICS CLINICAL APPLICATIONS

PURPOSE: For the vast majority of ovarian cancer patients, optimal surgical debulking remains a key prognostic factor associated w..

Quantitative proteomic analysis of EZH2 inhibition in acute myeloid leukemia reveals the targets and pathways that precede the induction of cell death

Jarrod J Sandow, Giuseppe Infusini, Aliaksei Z Holik, Gabriela Brumatti, Tessa V Averink, Paul G Ekert, Andrew I Webb

Journal article  |  2017  |  PROTEOMICS CLINICAL APPLICATIONS

PURPOSE: Chromosomal translocation of the mixed lineage leukemia (MLL) locus generates fusion proteins that drive acute myeloid le..