Giuseppe Infusini

Simplifying MS1 and MS2 spectra to achieve lower mass error, more dynamic range, and higher peptide identification confidence on the Bruker timsTOF Pro.

Daryl Wilding-McBride, Laura F Dagley, Sukhdeep K Spall, Giuseppe Infusini, Andrew I Webb

Journal article  |  2022  |  PLoS One

For bottom-up proteomic analysis, the goal of analytical pipelines that process the raw output of mass spectrometers is to detect,..

Mass Dynamics 1.0: A Streamlined, Web-Based Environment for Analyzing, Sharing, and Integrating Label-Free Data

Joseph Bloom, Aaron Triantafyllidis, Anna Quaglieri, Paula Burton Ngov, Giuseppe Infusini, Andrew Webb

Journal article  |  2021  |  JOURNAL OF PROTEOME RESEARCH

Label-free quantification (LFQ) of shotgun proteomics data is a popular and robust method for the characterization of relative pro..

Dynamic reconfiguration of pro-apoptotic BAK on membranes

Jarrod J Sandow, Iris Kl Tan, Alan S Huang, Shashank Masaldan, Jonathan P Bernardini, Ahmad Z Wardak, Richard W Birkinshaw, Robert L Ninnis, Ziyan Liu, Destiny Dalseno, Daisy Lio, Giuseppi Infusini, Peter E Czabotar, Andrew Webb, Grant Dewson

Journal article  |  2021  |  EMBO JOURNAL

BAK and BAX, the effectors of intrinsic apoptosis, each undergo major reconfiguration to an activated conformer that self-associat..

Sperm proteins and cancer-testis antigens are released by the seminiferous tubules in mice and men

Liza O'Donnell, Diane Rebourcet, Laura F Dagley, Raouda Sgaier, Giuseppe Infusini, Peter J O'Shaughnessy, Frederic Chalmel, Daniela Fietz, Wolfgang Weidner, Julien MD Legrand, Robin M Hobbs, Robert McLachlan, Andrew Webb, Adrian Pilatz, Thorsten Diemer, Lee B Smith, Peter G Stanton

Journal article  |  2021  |  FASEB JOURNAL

Sperm develop from puberty in the seminiferous tubules, inside the blood-testis barrier to prevent their recognition as "non-self"..

Physiological substrates and ontogeny-specific expression of the ubiquitin ligases MARCH1 and MARCH8.

Patrick Schriek, Haiyin Liu, Alan C Ching, Pauline Huang, Nishma Gupta, Kayla R Wilson, MinHsuang Tsai, Yuting Yan, Christophe F Macri, Laura F Dagley, Giuseppe Infusini, Andrew I Webb, Hamish EG McWilliam, Satoshi Ishido, Justine D Mintern, Jose A Villadangos

Journal article  |  2021  |  Curr Res Immunol

MARCH1 and MARCH8 are ubiquitin ligases that control the expression and trafficking of critical immunoreceptors. Understanding of ..

Serum microRNA is a biomarker for post-operative monitoring in glioma

Andrew Morokoff, Jordan Jones, Hong Nguyen, Chenkai Ma, Arian Lasocki, Frank Gaillard, Iwan Bennett, Rod Luwor, Stanley Stylli, Lucia Paradiso, Rachel Koldej, Iddo Paldor, Ramyar Molania, Terence P Speed, Andrew Webb, Guiseppe Infusini, Jason Li, Charles Malpas, Tomas Kalincik, Katharine Drummond, et al.

Journal article  |  2020  |  JOURNAL OF NEURO-ONCOLOGY

PURPOSE: A circulating biomarker has potential to provide more accurate information for glioma progression post treatment, however..

Airway Exosomes Released During Influenza Virus Infection Serve as a Key Component of the Antiviral Innate Immune Response

James G Bedford, Giuseppe Infusini, Laura F Dagley, Fernando Villalon-Letelier, Ming ZM Zheng, Vicki Bennett-Wood, Patrick C Reading, Linda M Wakim

Journal article  |  2020  |  FRONTIERS IN IMMUNOLOGY

Exosomes are extracellular vesicles secreted by cells that have an important biological function in intercellular communication by..

Universal Solid-Phase Protein Preparation (USP3) for Bottom-up and Top-down Proteomics

Laura F Dagley, Giuseppe Infusini, Rune H Larsen, Jarrod J Sandow, Andrew I Webb

Journal article  |  2019  |  JOURNAL OF PROTEOME RESEARCH

Selecting a sample preparation strategy for mass spectrometry-based proteomics is critical to the success of quantitative workflow..

Menstrual fluid factors facilitate tissue repair: identification and functional action in endometrial and skin repair.

Jemma Evans, Giuseppe Infusini, Jacqui McGovern, Leila Cuttle, Andrew Webb, Thomas Nebl, Liz Milla, Roy Kimble, Margit Kempf, Christine J Andrews, David Leavesley, Lois A Salamonsen

Journal article  |  2019  |  FASEB J

Repair after damage is essential for tissue homeostasis. Postmenstrual endometrial repair is a cyclical manifestation of rapid, sc..

Aspartyl Protease 5 Matures Dense Granule Proteins That Reside at the Host-Parasite Interface in Toxoplasma gondii

Michael J Coffey, Laura F Dagley, Simona Seizova, Eugene A Kapp, Giuseppe Infusini, David S Roos, Justin A Boddey, Andrew I Webb, Christopher J Tonkin

Journal article  |  2018  |  MBIO

Toxoplasma gondii infects approximately 30% of the world's population, causing disease primarily during pregnancy and in individua..