James Beeson

Defining species-specific and conserved interactions of apical membrane protein 1 during erythrocyte invasion in malaria to inform multi-species vaccines

Damien R Drew, Danny W Wilson, Gretchen E Weiss, Lee M Yeoh, Isabelle G Henshall, Brendan S Crabb, Sheetij Dutta, Paul R Gilson, James G Beeson

Journal article  |  2023  |  CELLULAR AND MOLECULAR LIFE SCIENCES

Plasmodium falciparum and P. vivax are the major causes of human malaria, and P. knowlesi is an important additional cause in SE A..

Low knowledge of newborn danger signs among pregnant women in Papua New Guinea and implications for health seeking behaviour in early infancy - findings from a longitudinal study.

Donya Eghrari, Michelle JL Scoullar, Alyce N Wilson, Elizabeth Peach, Arthur Elijah, Pele Melepia, Hadlee SupSup, Lisa M Vallely, Peter M Siba, Elissa C Kennedy, Joshua P Vogel, Caroline SE Homer, Leanne J Robinson, Freya JI Fowkes, William Pomat, Brendan S Crabb, James G Beeson, Christopher J Morgan

Journal article  |  2023  |  BMC Pregnancy Childbirth

BACKGROUND: Globally, 2.5 million babies die in the first 28 days of life each year with most of these deaths occurring in low- an..

Fc engineered ACE2-Fc is a potent multifunctional agent targeting SARS-CoV2 (vol 13, 889372, 2022)

Bruce D Wines, Liriye Kurtovic, Halina M Trist, Sandra Esparon, Ester Lopez, Klasina Chappin, Li-Jin Chan, Francesca L Mordant, Wen Shi Lee, Nicholas A Gherardin, Sheila K Patel, Gemma E Hartley, Phillip Pymm, James P Cooney, James G Beeson, Dale I Godfrey, Louise M Burrell, Menno C van Zelm, Adam K Wheatley, Amy WW Chung, et al.

Journal article  |  2023  |  FRONTIERS IN IMMUNOLOGY

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The direct binding of Plasmodium vivax AMA1 to erythrocytes defines a RON2-independent invasion pathway.

Seong-Kyun Lee, Leanne M Low, John F Andersen, Lee M Yeoh, Paola Carolina Valenzuela Leon, Damien R Drew, Johannes SP Doehl, Eric Calvo, Louis H Miller, James G Beeson, Karthigayan Gunalan

Journal article  |  2023  |  Proc Natl Acad Sci U S A

We used a transgenic parasite in which Plasmodium falciparum parasites were genetically modified to express Plasmodium vivax apica..

Targeting malaria parasites with novel derivatives of azithromycin

Amy L Burns, Brad E Sleebs, Maria Gancheva, Kimberley T McLean, Ghizal Siddiqui, Henrietta Venter, James G Beeson, Ryan O'Handley, Darren J Creek, Shutao Ma, Sonja Froelich, Christopher D Goodman, Geoffrey McFadden, Danny W Wilson

Journal article  |  2022  |  FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

INTRODUCTION: The spread of artemisinin resistant Plasmodium falciparum parasites is of global concern and highlights the need to ..

The RTS,S malaria vaccine: Current impact and foundation for the future

James G Beeson, Liriye Kurtovic, Clarissa Valim, Kwaku Poku Asante, Michelle J Boyle, Don Mathanga, Carlota Dobano, Gemma Moncunill

Journal article  |  2022  |  SCIENCE TRANSLATIONAL MEDICINE

The RTS,S vaccine has recently been recommended for implementation as a childhood vaccine in regions with moderate-to-high malaria..

Impact of Environmental Modifications on the Ecology, Epidemiology, and Pathogenesis of Plasmodium falciparum and Plasmodium vivax Malaria in East Africa.

Guiyun Yan, Ming-Chieh Lee, Guofa Zhou, Ai-Ling Jiang, Teshome Degefa, Daibin Zhong, Xiaoming Wang, Elizabeth Hemming-Schroeder, Wolfgang R Mukabana, Arlene E Dent, Christopher L King, Kuolin Hsu, James Beeson, John I Githure, Harrysone Atieli, Andrew K Githeko, Delenasaw Yewhalaw, James W Kazura

Journal article  |  2022  |  Am J Trop Med Hyg

Food insecurity, recurrent famine, and poverty threaten the health of millions of African residents. Construction of dams and rura..

Asia-Pacific ICEMR: Understanding Malaria Transmission to Accelerate Malaria Elimination in the Asia Pacific Region.

Ivo Mueller, Amelie Vantaux, Stephan Karl, Moses Laman, Benoit Witkowski, Anais Pepey, Rebecca Vinit, Michael White, Alyssa Barry, James G Beeson, Leanne J Robinson

Journal article  |  2022  |  Am J Trop Med Hyg

Gaining an in-depth understanding of malaria transmission requires integrated, multifaceted research approaches. The Asia-Pacific ..

Induction, decay, and determinants of functional antibodies following vaccination with the RTS,S malaria vaccine in young children

Gaoqian Feng, Liriye Kurtovic, Paul A Agius, Elizabeth H Aitken, Jahit Sacarlal, Bruce D Wines, P Mark Hogarth, Stephen J Rogerson, Freya J Fowkes, Carlota Dobano, James G Beeson

Journal article  |  2022  |  BMC MEDICINE

BACKGROUND: RTS,S is the first malaria vaccine recommended for implementation among young children at risk. However, vaccine effic..

Author Correction: Antibody responses to the RTS,S/AS01E vaccine and Plasmodium falciparum antigens after a booster dose within the phase 3 trial in Mozambique.

Lina Sánchez, Marta Vidal, Chenjerai Jairoce, Ruth Aguilar, Itziar Ubillos, Inocencia Cuamba, Augusto J Nhabomba, Nana Aba Williams, Núria Díez-Padrisa, David Cavanagh, Evelina Angov, Ross L Coppel, Deepak Gaur, James G Beeson, Sheetij Dutta, Pedro Aide, Joseph J Campo, Gemma Moncunill, Carlota Dobaño

Journal article  |  2022  |  NPJ Vaccines

In the original version of this Article, the Data Availability statement was missing the link to the datasets generated during the..