Khalid Mahmood

Tumor mutational signatures in sebaceous skin lesions from individuals with Lynch syndrome

Peter Georgeson, Michael D Walsh, Mark Clendenning, Simin Daneshvar, Bernard J Pope, Khalid Mahmood, Jihoon E Joo, Harindra Jayasekara, Mark A Jenkins, Ingrid M Winship, Daniel D Buchanan

Journal article  |  2019  |  Molecular Genetics & Genomic Medicine

sEst: Accurate Sex-Estimation and Abnormality Detection in Methylation Microarray Data

Chol-Hee Jung, Daniel J Park, Peter Georgeson, Khalid Mahmood, Roger L Milne, Melissa C Southey, Bernard J Pope

Journal article  |  2018  |  International Journal of Molecular Sciences

Risk of colorectal cancer for carriers of a germ-line mutation in POLE or POLD1

Daniel D Buchanan, Jenna R Stewart, Mark Clendenning, Christophe Rosty, Khalid Mahmood, Bernard J Pope, Mark A Jenkins, John L Hopper, Melissa C Southey, Finlay A Macrae, Ingrid M Winship, Aung Ko Win

Journal article  |  2018  |  Genet Med

Is RNASEL:p.Glu265*a modifier of early-onset breast cancer risk for carriers of high-risk mutations?

Tu Nguyen-Dumont, Zhi L Teo, Fleur Hammet, Alexis Roberge, Maryam Mahmoodi, Helen Tsimiklis, Daniel J Park, Bernard J Pope, Andrew Lonie, Miroslav K Kapuscinski, Khalid Mahmood, David E Goldgar, Graham G Giles, Ingrid Winship, John L Hopper, Melissa C Southey

Journal article  |  2018  |  BMC Cancer

Variant effect prediction tools assessed using independent, functional assay-based datasets: implications for discovery and diagnostics

Khalid Mahmood, Chol-hee Jung, Gayle Philip, Peter Georgeson, Jessica Chung, Bernard J Pope, Daniel J Park

Journal article  |  2017  |  Human Genomics

Single nucleotide-level mapping of DNA double-strand breaks in human HEK293T cells

Bernard J Pope, Khalid Mahmood, Chol-hee Jung, Peter Georgeson, Daniel J Park

Journal article  |  2017  |  Genomics Data

Fine resolution mapping of double-strand break sites for human ribosomal DNA units

Bernard J Pope, Khalid Mahmood, Chol-hee Jung, Daniel J Park

Journal article  |  2016  |  Genomics Data

Mutation of the nuclear lamin gene LMNB2 in progressive myoclonus epilepsy with early ataxia

John A Damiano, Zaid Afawi, Melanie Bahlo, Monika Mauermann, Adel Misk, Todor Arsov, Karen L Oliver, Hans-Henrik M Dahl, A Eliot Shearer, Richard JH Smith, Nathan E Hall, Khalid Mahmood, Richard J Leventer, Ingrid E Scheffer, Mikko Muona, Anna-Elina Lehesjoki, Amos D Korczyn, Harald Herrmann, Samuel F Berkovic, Michael S Hildebrand

Journal article  |  2015  |  Human Molecular Genetics

Predicting giant transmembrane beta-barrel architecture

Cyril F Reboul, Khalid Mahmood, James C Whisstock, Michelle A Dunstone

Journal article  |  2012  |  Bioinformatics

MOTIVATION: The β-barrel is a ubiquitous fold that is deployed to accomplish a wide variety of biological functions including memb..

Efficient large-scale protein sequence comparison and gene matching to identify orthologs and co-orthologs

Khalid Mahmood, Geoffrey I Webb, Jiangning Song, James C Whisstock, Arun S Konagurthu

Journal article  |  2012  |  Nucleic Acids Research

BIOINFORMATIC APPROACHES FOR PREDICTING SUBSTRATES OF PROTEASES

Jiangning Song, Hao Tan, Sarah E Boyd, Hongbin Shen, Khalid Mahmood, Geoffrey I Webb, Tatsuya Akutsu, James C Whisstock, Robert N Pike

Journal article  |  2011  |  Journal of Bioinformatics and Computational Biology

EGM: encapsulated gene-by-gene matching to identify gene orthologs and homologous segments in genomes

Khalid Mahmood, Arun S Konagurthu, Jiangning Song, Ashley M Buckle, Geoffrey I Webb, James C Whisstock

Journal article  |  2010  |  Bioinformatics

Cascleave: towards more accurate prediction of caspase substrate cleavage sites

Jiangning Song, Hao Tan, Hongbin Shen, Khalid Mahmood, Sarah E Boyd, Geoffrey I Webb, Tatsuya Akutsu, James C Whisstock

Journal article  |  2010  |  Bioinformatics

Prodepth: Predict Residue Depth by Support Vector Regression Approach from Protein Sequences Only

Jiangning Song, Hao Tan, Khalid Mahmood, Ruby HP Law, Ashley M Buckle, Geoffrey I Webb, Tatsuya Akutsu, James C Whisstock

Journal article  |  2009  |  PLoS ONE

eResearch solutions for high throughput structural biology

N Faux, A Beitz, M Bate, AA Amin, I Atkinson, C Enticott, K Mahmood, M Swift, A Treloar, D Abramson, JC Whisstock, AM Buckle

Conference Proceedings  |  2007  |  Third IEEE International Conference on e-Science and Grid Computing (e-Science 2007)

RCPdb: An evolutionary classification and codon usage database for repeat-containing proteins

Noel G Faux, Gavin A Huttley, Khalid Mahmood, Geoffrey I Webb, Maria Garcia de la Banda, James C Whisstock

Journal article  |  2007  |  Genome Research

GABA production by glutamic acid decarboxylase is regulated by a dynamic catalytic loop

Gustavo Fenalti, Ruby HP Law, Ashley M Buckle, Christopher Langendorf, Kellie Tuck, Carlos J Rosado, Noel G Faux, Khalid Mahmood, Christiane S Hampe, J Paul Banga, Matthew Wilce, Jason Schmidberger, Jamie Rossjohn, Ossama El-Kabbani, Robert N Pike, A Ian Smith, Ian R Mackay, Merrill J Rowley, James C Whisstock

Journal article  |  2007  |  Nature Structural & Molecular Biology

Protein Folding Database (PFD 2.0): an online environment for the International Foldeomics Consortium

Kate F Fulton, Mark A Bate, Noel G Faux, Khalid Mahmood, Chris Betts, Ashley M Buckle

Journal article  |  2007  |  Nucleic Acids Research