My current research is focused on understanding how genetic, neurochemical and structural changes that occur in the brain in hypertension and following myocardial infarction contributes to an overactive sympathetic nervous system and consequently disease progression. Current research projects include identifying and understanding the function of specific cytokines and their role in furthering hypertension and heart failure progression.
Another area of interest is the blood brain barrier and its integrity in hypertension and heart failure.
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Chemoattraction and Recruitment of Activated Immune Cells, Central Autonomic Control, and ..
Blunted diuretic and natriuretic responses to acute sodium loading early after catheter-ba..
Displaying the 6 most recent projects by Song Yao.
Internal Research Grant
Displaying the 70 most recent scholarly works by Song Yao.
Systemic administration of pentoxifylline attenuates the development of hypertension in renovascular hypertensive rats
Anthony Setiadi, Willian S Korim, Clive N May, Song T Yao
Journal article | 2020 | Hypertension Research
There is evidence to suggest that hypertension involves a chronic low-grade systemic inflammatory response; however, the underlyin..
Blunted diuretic and natriuretic responses to acute sodium loading early after catheter-based renal denervation in normotensive sheep
Zoe McArdle, Roberto B Pontes, Song T Yao, Yugeh R Lankadeva, Reetu R Singh, Sally G Hood, Markus P Schlaich, Clive N May, Lindsea C Booth
Journal article | 2019 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Catheter-based renal denervation (RDN) was introduced as a treatment for resistant hypertension. There remain critical questions r..
Stretchable Low Impedance Electrodes for Bioelectronic Recording from Small Peripheral Nerves
Francesco Decataldo, Tobias Cramer, Davide Martelli, Isacco Gualandi, Willian S Korim, Song T Yao, Marta Tessarolo, Mauro Murgia, Erika Scavetta, Roberto Amici, Beatrice Fraboni
Journal article | 2019 | Scientific Reports
Monitoring of bioelectric signals in peripheral sympathetic nerves of small animal models is crucial to gain understanding of how ..
A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1
Mohammed Akhter Hossain, Martina Kocan, Song T Yao, Simon G Royce, Vinojini B Nair, Christopher Siwek, Nitin A Patil, Ian P Harrison, K Johan Rosengren, Stavros Selemidis, Roger J Summers, John D Wade, Ross AD Bathgate, Chrishan S Samuel
Journal article | 2016 | Chemical Science
Short-term effects of catheter-based renal denervation on cardiac sympathetic drive and cardiac baroreflex function in heart failure
Lindsea C Booth, Markus P Schlaich, Erika E Nishi, Song T Yao, Jianzhong Xu, Rohit Ramchandra, Gavin W Lambert, Clive N May
Journal article | 2015 | International journal of cardiology
Osmoregulation Requires Brain Expression of the Renal Na-K-2Cl Cotransporter NKCC2
Agnieszka Konopacka, Jing Qiu, Song T Yao, Michael P Greenwood, Mingkwan Greenwood, Thomas Lancaster, Wataru Inoue, Andre de Souza Mecawi, Fernanda MV Vechiato, Juliana BM de Lima, Ricardo Coletti, See Ziau Hoe, Andrew Martin, Justina Lee, Marina Joseph, Charles Hindmarch, Julian Paton, Jose Antunes-Rodrigues, Jaideep Bains, David Murphy
Journal article | 2015 | The Journal of Neuroscience
The Use of Protein-DNA, Chromatin Immunoprecipitation, and Transcriptome Arrays to Describe Transcriptional Circuits in the Dehydrated Male Rat Hypothalamus
Jing Qiu, Anna Kleineidam, Sabine Gouraud, Song Tieng Yao, Mingkwan Greenwood, See Ziau Hoe, Charles Hindmarch, David Murphy
Journal article | 2014 | Endocrinology
Reflex control of inflammation by the splanchnic anti-inflammatory pathway is sustained and independent of anesthesia
Davide Martelli, Song T Yao, Julian Mancera, Michael J McKinley, Robin M McAllen
Journal article | 2014 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Anteroventral third ventricle (AV3V) lesion affects hypothalamic neuronal nitric oxide synthase (nNOS) expression following water deprivation
Fabio Alves Aguila, Gabriela Ravanelli Oliveira-Pelegrin, Song Tieng Yao, David Murphy, Maria Jose Alves Rocha
Journal article | 2011 | Brain research bulletin
Temporal profile of arginine vasopressin release from the neurohypophysis in response to hypertonic saline and hypotension measured using a fluorescent fusion protein
Song T Yao, Vagner R Antunes, Peter MJ Bradley, Sergey Kasparov, Yoichi Ueta, Julian FR Paton, David Murphy
Journal article | 2011 | Journal of neuroscience methods
Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration
Debora SA Colombari, Eduardo Colombari, Andre H Freiria-Oliveira, Vagner R Antunes, Song T Yao, Charles Hindmarch, Alastair V Ferguson, Mark Fry, David Murphy, Julian FR Paton
Journal article | 2011 | The Journal of physiology
The transcriptome of the medullary area postrema: the thirsty rat, the hungry rat and the hypertensive rat
Charles CT Hindmarch, Mark Fry, Pauline M Smith, Song T Yao, Georgina GJ Hazell, Stephen J Lolait, Julian FR Paton, Alastair V Ferguson, David Murphy
Journal article | 2011 | Experimental physiology
Cardioprotection, attenuated systemic inflammation, and survival benefit of beta(1)-adrenoceptor blockade in severe sepsis in rats
Gareth L Ackland, Song T Yao, Alain Rudiger, Alex Dyson, Ray Stidwill, Dmitry Poputnikov, Mervyn Singer, Alexander V Gourine
Journal article | 2010 | Critical care medicine
Microarray analysis of the transcriptome of the subfornical organ in the rat: regulation by fluid and food deprivation
Charles Hindmarch, Mark Fry, Song T Yao, Pauline M Smith, David Murphy, Alastair V Ferguson
Journal article | 2008 | American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Transcription factor expression in the hypothalamo-neurohypophyseal system of the dehydrated rat: Upregulation of gonadotrophin inducible transcription factor 1 mRNA is mediated by cAMP-dependent protein kinase A
Jing Qiu, Song Yao, Charles Hindmarch, Vagner Antunes, Julian Paton, David Murphy
Journal article | 2007 | The Journal of neuroscience
Comparative study on the distribution patterns of P2X(1)-P2X(6) receptor immunoreactivity in the brainstem of the rat and the common marmoset (Callithrix jacchus): Association with catecholamine cell groups
ST Yao, JA Barden, DI Finkelstein, MR Bennett, AJ Lawrence
Journal article | 2000 | Journal of Comparative Neurology
Honours, Awards and Fellowships
Senior Research Fellow
Florey Department Of Neuroscience And Mental Health
International Society of Autonomic Neuroscience
Physiological Society (UK)
American Physiological Soceity
High Blood Pressure Research Council of Australia
Australian Neuroscience Society