Sara Erickson

Targeting the Extrinsic Pathway of Hepatocyte Apoptosis Promotes Clearance of Plasmodium Liver Infection

Gregor Ebert, Sash Lopaticki, Matthew T O'Neill, Ryan WJ Steel, Marcel Doerflinger, Pravin Rajasekaran, Annie SP Yang, Sara Erickson, Lisa Ioannidis, Philip Arandjelovic, Liana Mackiewicz, Cody Allison, John Silke, Marc Pellegrini, Justin A Boddey

Journal article  |  2020  |  CELL REPORTS

Plasmodium sporozoites infect the liver and develop into exoerythrocytic merozoites that initiate blood-stage disease. The hepatoc..

Inhibition of Plasmepsin V Activity Blocks Plasmodium falciparum Gametocytogenesis and Transmission to Mosquitoes

Charlie Jennison, Leonardo Lucantoni, Matthew T O'Neill, Robyn McConville, Sara M Erickson, Alan F Cowman, Brad E Sleebs, Vicky M Avery, Justin A Boddey

Journal article  |  2019  |  CELL REPORTS

Plasmodium falciparum gametocytes infect mosquitoes and are responsible for malaria transmission. New interventions that block tra..

Malaria surveillance from both ends: concurrent detection of Plasmodium falciparum in saliva and excreta harvested from Anopheles mosquitoes

Ana L Ramirez, Andrew F van den Hurk, Ian M Mackay, Annie SP Yang, Glen R Hewitson, Jamie L McMahon, Justin A Boddey, Scott A Ritchie, Sara M Erickson

Journal article  |  2019  |  PARASITES & VECTORS

BACKGROUND: Malaria is the most important vector-borne disease in the world. Epidemiological and ecological studies of malaria tra..

Plasmodium falciparum subtilisin-like ookinete protein SOPT plays an important and conserved role during ookinete infection of the Anopheles stephensi midgut

Jennifer S Armistead, Charlie Jennison, Matthew T O'Neill, Sash Lopaticki, Peter Liehl, Kirsten K Hanson, Takeshi Annoura, Pravin Rajasekaran, Sara M Erickson, Christopher J Tonkin, Shahid M Khan, Maria M Mota, Justin A Boddey

Journal article  |  2018  |  MOLECULAR MICROBIOLOGY

Transmission of the malaria parasite Plasmodium falciparum involves infection of Anopheles mosquitoes. Here we characterize SOPT, ..

Protein O-fucosylation in Plasmodium falciparum ensures efficient infection of mosquito and vertebrate hosts

Sash Lopaticki, Annie SP Yang, Alan John, Nichollas E Scott, James P Lingford, Matthew T O'Neill, Sara M Erickson, Nicole C McKenzie, Charlie Jennison, Lachlan W Whitehead, Donna N Douglas, Norman M Kneteman, Ethan D Goddard-Borger, Justin A Boddey

Journal article  |  2017  |  NATURE COMMUNICATIONS

O-glycosylation of the Plasmodium sporozoite surface proteins CSP and TRAP was recently identified, but the role of this modificat..

AMA1 and MAEBL are important for Plasmodium falciparum sporozoite infection of the liver

Annie SP Yang, Sash Lopaticki, Matthew T O'Neill, Sara M Erickson, Donna N Douglas, Norman M Kneteman, Justin A Boddey

Journal article  |  2017  |  CELLULAR MICROBIOLOGY

The malaria sporozoite injected by a mosquito migrates to the liver by traversing host cells. The sporozoite also traverses hepato..

Cell Traversal Activity Is Important for Plasmodium falciparum Liver Infection in Humanized Mice

Annie SP Yang, Matthew T O'Neill, Charlie Jennison, Sash Lopaticki, Cody C Allison, Jennifer S Armistead, Sara M Erickson, Kelly L Rogers, Andrew M Ellisdon, James C Whisstock, Rebecca E Tweedell, Rhoel R Dinglasan, Donna N Douglas, Norman M Kneteman, Justin A Boddey

Journal article  |  2017  |  CELL REPORTS

Malaria sporozoites are deposited into the skin by mosquitoes and infect hepatocytes. The molecular basis of how Plasmodium falcip..

Dual RNA-seq of parasite and host reveals gene expression dynamics during filarial worm-mosquito interactions.

Young-Jun Choi, Matthew T Aliota, George F Mayhew, Sara M Erickson, Bruce M Christensen

Journal article  |  2014  |  PLoS Negl Trop Dis

BACKGROUND: Parasite biology, by its very nature, cannot be understood without integrating it with that of the host, nor can the h..

Mosquito-Parasite Interactions Can Shape Filariasis Transmission Dynamics and Impact Elimination Programs

Sara M Erickson, Edward K Thomsen, John B Keven, Naomi Vincent, Gussy Koimbu, Peter M Siba, Bruce M Christensen, Lisa J Reimer

Journal article  |  2013  |  PLOS NEGLECTED TROPICAL DISEASES

The relationship between mosquito vectors and lymphatic filariasis (LF) parasites can result in a range of transmission outcomes. ..

Resident alveolar macrophages are susceptible to and permissive of Coxiella burnetii infection.

Matthew Calverley, Sara Erickson, Amanda J Read, Allen G Harmsen

Journal article  |  2012  |  PLoS One

Coxiella burnetii, the causative agent of Q fever, is a zoonotic disease with potentially life-threatening complications in humans..