Ana Janic

Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis

Sarah A Best, Cassandra J Vandenberg, Etna Abad, Lachlan Whitehead, Laia Guiu, Sheryl Ding, Margs S Brennan, Andreas Strasser, Marco J Herold, Kate D Sutherland, Ana Janic

Journal article  |  2020  |  Cell Death and Disease

TP53 is a critical tumor suppressor that is mutated in approximately 50% of human cancers. Unveiling the downstream target genes o..

Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development

Brandon J Aubrey, Ana Janic, Yunshun Chen, Catherine Chang, Elizabeth C Lieschke, Sarah T Diepstraten, Andrew J Kueh, Jonathan P Bernardini, Grant Dewson, Lorraine A O'Reilly, Lachlan Whitehead, Anne K Voss, Gordon K Smyth, Andreas Strasser, Gemma L Kelly

Journal article  |  2018  |  Genes & Development

DNA repair processes are critical mediators of p53-dependent tumor suppression

Ana Janic, Liz J Valente, Matthew J Wakefield, Leon Di Stefano, Liz Milla, Stephen Wilcox, Haoyu Yang, Lin Tai, Cassandra J Vandenberg, Andrew J Kueh, Shinsuke Mizutani, Margs S Brennan, Robyn L Schenk, Lisa M Lindqvist, Anthony T Papenfuss, Liam O'Connor, Andreas Strasser, Marco J Herold

Journal article  |  2018  |  Nature Medicine

How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression?

Brandon J Aubrey, Gemma L Kelly, Ana Janic, Marco J Herold, Andreas Strasser

Journal article  |  2018  |  Cell Death & Differentiation

Stimulating p53 down-under: a report from the 1st Australian p53 Workshop

PM Neilsen, AW Braithwaite, C Gamell, S Haupt, A Janic, A Strasser, K Wolyniec, Y Haupt

Journal article  |  2013  |  Cell Death & Differentiation

p53 Efficiently Suppresses Tumor Development in the Complete Absence of Its Cell-Cycle Inhibitory and Proapoptotic Effectors p21, Puma, and Noxa

Liz J Valente, Daniel HD Gray, Ewa M Michalak, Josefina Pinon-Hofbauer, Alex Egle, Clare L Scott, Ana Janic, Andreas Strasser

Journal article  |  2013  |  Cell Reports

Surgical crown lengthening in a population with human immunodeficiency virus: a retrospective analysis).

Shilpa Kolhatkar, Suzanne A Mason, Ana Janic, Monish Bhola, Shaziya Haque, James R Winkler

Journal article  |  2012  |  JOURNAL OF PERIODONTOLOGY

BACKGROUND: Individuals with human immunodeficiency virus (HIV) have an increased risk of developing health problems, including so..

Ectopic Expression of Germline Genes Drives Malignant Brain Tumor Growth in Drosophila

Ana Janic, Leire Mendizabal, Salud Llamazares, David Rossell, Cayetano Gonzalez

Journal article  |  2010  |  SCIENCE

Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling.

Anne-Marie Martinez, Bernd Schuettengruber, Samy Sakr, Ana Janic, Cayetano Gonzalez, Giacomo Cavalli

Journal article  |  2009  |  NATURE GENETICS

Polycomb Group (PcG) proteins silence critical developmental genes and modulate cell proliferation. Using the Drosophila melanogas..