Paul Klauser

The 2019 ESCAP research academy workshop: how novel technologies are impacting child and adolescent psychiatry.

Paul Klauser, Johannes Hebebrand, Laura A Kehoe, Mercedes Huscsava, Alexis Revet

Journal article  |  2020  |  European Child & Adolescent Psychiatry

N-Acetyl-Cysteine Supplementation Improves Functional Connectivity Within the Cingulate Cortex in Early Psychosis: A Pilot Study.

Emeline Mullier, Timo Roine, Alessandra Griffa, Lijing Xin, Philipp S Baumann, Paul Klauser, Martine Cleusix, Raoul Jenni, Yasser Alemàn-Gómez, Rolf Gruetter, Philippe Conus, Kim Q Do, Patric Hagmann

Journal article  |  2019  |  International Journal of Neuropsychopharmacology

BACKGROUND: There is increasing evidence that redox dysregulation, which can lead to oxidative stress and eventually to impairment..

Frontal cortical thickness correlates positively with impulsivity in early psychosis male patients.

Philipp S Baumann, Paul Klauser, Alessandra Griffa, Philippe Golay, Julie Palix, Luis Alameda, Valérie Moulin, Patric Hagmann, Kim Q Do, Philippe Conus

Journal article  |  2019  |  Early Intervention in Psychiatry

AIM: Impulsive behaviours, which are frequent in young people suffering from psychosis have been linked to risky and violent behav..

Brain connectivity alterations in early psychosis: from clinical to neuroimaging staging.

Alessandra Griffa, Philipp S Baumann, Paul Klauser, Emeline Mullier, Martine Cleusix, Raoul Jenni, Martijn P van den Heuvel, Kim Q Do, Philippe Conus, Patric Hagmann

Journal article  |  2019  |  Translational Psychiatry

Early in the course of psychosis, alterations in brain connectivity accompany the emergence of psychiatric symptoms and cognitive ..

MMP9/RAGE pathway overactivation mediates redox dysregulation and neuroinflammation, leading to inhibitory/excitatory imbalance: a reverse translation study in schizophrenia patients

D Dwir, B Giangreco, L Xin, L Tenenbaum, JH Cabungcal, P Steullet, A Goupil, M Cleusix, R Jenni, PS Baumann, P Klauser, P Conus, R Tirouvanziam, M Cuenod, KQ Do

Journal article  |  2019  |  Molecular Psychiatry

Redox dysregulation as a link between childhood trauma and psychopathological and neurocognitive profile in patients with early psychosis.

Luis Alameda, Margot Fournier, Ines Khadimallah, Alessandra Griffa, Martine Cleusix, Raoul Jenni, Carina Ferrari, Paul Klauser, Philipp S Baumann, Michel Cuenod, Patric Hagmann, Philippe Conus, Kim Q Do

Journal article  |  2018  |  Proceedings of the National Academy of Sciences

Exposure to childhood trauma (CT) increases the risk for psychosis and affects the development of brain structures, possibly throu..

N-acetylcysteine add-on treatment leads to an improvement of fornix white matter integrity in early psychosis: a double-blind randomized placebo-controlled trial.

Paul Klauser, Lijing Xin, Margot Fournier, Alessandra Griffa, Martine Cleusix, Raoul Jenni, Michel Cuenod, Rolf Gruetter, Patric Hagmann, Philippe Conus, Philipp S Baumann, Kim Q Do

Journal article  |  2018  |  Translational Psychiatry

Mechanism-based treatments for schizophrenia are needed, and increasing evidence suggests that oxidative stress may be a target. P..

Widespread white matter microstructural differences in schizophrenia across 4322 individuals: results from the ENIGMA Schizophrenia DTI Working Group

S Kelly, N Jahanshad, A Zalesky, P Kochunov, I Agartz, C Alloza, OA Andreassen, C Arango, N Banaj, S Bouix, CA Bousman, RM Brouwer, J Bruggemann, J Bustillo, W Cahn, V Calhoun, D Cannon, V Carr, S Catts, J Chen, et al.

Journal article  |  2018  |  Molecular Psychiatry

CHILDHOOD TRAUMA ENGAGES OXIDATIVE STRESS, HIPPOCAMPUS ALTERATIONS, AND POORER CLINICAL OUTCOME IN EARLY PSYCHOSIS PATIENTS

Luis Alameda, Margot Fournier, Ines Khadimallah, Philippe S Baumann, Martine Cleusix, Alessandra Griffa, Paul Klauser, Raoul Jenni, Michel Cuenod, Patric Hagmann, Philippe Conus, Kim Do

Conference Proceedings  |  2018  |  SCHIZOPHRENIA BULLETIN

Neuregulin-1 (NRG1) polymorphisms linked with psychosis transition are associated with enlarged lateral ventricles and white matter disruption in schizophrenia

CA Bousman, V Cropley, P Klauser, JL Hess, A Pereira, R Idrizi, J Bruggemann, MS Mostaid, R Lenroot, TW Weickert, SJ Glatt, IP Everall, S Sundram, A Zalesky, CS Weickert, C Pantelis

Journal article  |  2018  |  Psychological Medicine

Dual training as clinician-scientist in child and adolescent psychiatry: are we there yet?

Alexis Revet, Johannes Hebebrand, Sampada Bhide, Joao Caseiro, Eugenia Conti, Marike Deutz, Andra Isac, Athanasios Kanellopoulos, Tugba Kalyoncu, Katri Maasalo, Silvana Markovska-Simoska, Marija Mitkovic-Voncina, Silvia Molteni, Mariela Mosheva, Susanne Mudra, Julia Philipp, Cecil Prins-Aardema, Marina Romero Gonzalez, Antonin Sebela, Jochen Seitz, et al.

Journal article  |  2018  |  European Child & Adolescent Psychiatry

Differential effect of disease-associated ST8S/A2 haplotype on cerebral white matter diffusion properties in schizophrenia and healthy controls

Janice M Fullerton, Paul Klauser, Rhoshel K Lenroot, Alex D Shaw, Bronwyn Overs, Anna Heath, Murray J Cairns, Joshua Atkins, Rodney Scott, Peter R Schofield, Cyndi Shannon Weickert, Christos Pantelis, Alex Fornito, Thomas J Whitford, Thomas W Weickert, Andrew Zalesky

Journal article  |  2018  |  Translational Psychiatry

Cannabis use in early psychosis is associated with reduced glutamate levels in the prefrontal cortex.

Silvia Rigucci, Lijing Xin, Paul Klauser, Philipp S Baumann, Luis Alameda, Martine Cleusix, Raoul Jenni, Carina Ferrari, Maurizio Pompili, Rolf Gruetter, Kim Q Do, Philippe Conus

Journal article  |  2018  |  Psychopharmacology

RATIONALE: Recent studies have shown that cannabis may disrupt glutamate (Glu) signaling depressing Glu tone in frequent users. Cu..

White Matter Disruptions in Schizophrenia Are Spatially Widespread and Topologically Converge on Brain Network Hubs

Paul Klauser, Simon T Baker, Vanessa L Cropley, Chad Bousman, Alex Fornito, Luca Cocchi, Janice M Fullerton, Paul Rasser, Ulrich Schall, Frans Henskens, Patricia T Michie, Carmel Loughland, Stanley V Catts, Bryan Mowry, Thomas W Weickert, Cynthia Shannon Weickert, Vaughan Carr, Rhoshel Lenroot, Christos Pantelis, Andrew Zalesky

Journal article  |  2017  |  Schizophrenia Bulletin

Accelerated Gray and White Matter Deterioration With Age in Schizophrenia

Vanessa L Cropley, Paul Klauser, Rhoshel K Lenroot, Jason Bruggemann, Suresh Sundram, Chad Bousman, Avril Pereira, Maria A Di Biase, Thomas W Weickert, Cynthia Shannon Weickert, Christos Pantelis, Andrew Zalesky

Journal article  |  2017  |  American Journal of Psychiatry

Neuroprotection after a first episode of mania: a randomized controlled maintenance trial comparing the effects of lithium and quetiapine on grey and white matter volume

M Berk, O Dandash, R Daglas, SM Cotton, K Allott, A Fornito, C Suo, P Klauser, B Liberg, L Henry, C Macneil, M Hasty, P McGorry, Cs Pantelis, M Yucel

Journal article  |  2017  |  Translational Psychiatry

Baseline grey matter volume of non-transitioned "ultra high risk" for psychosis individuals with and without attenuated psychotic symptoms at long-term follow-up

Vanessa L Cropley, Ashleigh Lin, Barnaby Nelson, Renate LEP Reniers, Alison R Yung, Cali F Bartholomeusz, Paul Klauser, Dennis Velakoulis, Patrick McGorry, Stephen J Wood, Christos Pantelis

Journal article  |  2016  |  SCHIZOPHRENIA RESEARCH

The effect of a muscarinic receptor 1 gene variant on grey matter volume in schizophrenia

Vanessa L Cropley, Elizabeth Scarr, Alex Fornito, Paul Klauser, Chad A Bousman, Rodney Scott, Murray J Cairns, Paul A Tooney, Christos Pantelis, Brian Dean

Journal article  |  2015  |  Psychiatry Research: Neuroimaging

Lack of Evidence for Regional Brain Volume or Cortical Thickness Abnormalities in Youths at Clinical High Risk for Psychosis: Findings From the Longitudinal Youth at Risk Study

Paul Klauser, Juan Zhou, Joseph KW Lim, Joann S Poh, Hui Zheng, Han Ying Tng, Ranga Krishnan, Jimmy Lee, Richard SE Keefe, R Alison Adcock, Stephen J Wood, Alex Fornito, Michael WL Chee

Journal article  |  2015  |  Schizophrenia Bulletin

Cortico-limbic network abnormalities in individuals with current and past major depressive disorder

Paul Klauser, Alex Fornito, Valentina Lorenzetti, Christopher G Davey, Dominic B Dwyer, Nicholas B Allen, Murat Yuecel

Journal article  |  2015  |  Journal of Affective Disorders

Reduced frontal white matter volume in children with early onset of adrenarche

Paul Klauser, Sarah Whittle, Julian G Simmons, Michelle L Byrne, Lisa K Mundy, George C Patton, Alex Fornito, Nicholas B Allen

Journal article  |  2015  |  Psychoneuroendocrinology

Functional and structural alterations in the cingulate motor area relate to decreased fronto-striatal coupling in major depressive disorder with psychomotor disturbances

Benny Liberg, Paul Klauser, Ian H Harding, Mats Adler, Christoffer Rahm, Johan Lundberg, Thomas Masterman, Caroline Wachtler, Tomas Jonsson, Maria Kristoffersen-Wiberg, Christos Pantelis, Bjorn Wahlund

Journal article  |  2014  |  Frontiers in Psychiatry

Reduced orbitofrontal cortical thickness in male adolescents with internet addiction

Soon-Beom Hong, Jae-Won Kim, Eun-Jung Choi, Ho-Hyun Kim, Jeong-Eun Suh, Chang-Dai Kim, Paul Klauser, Sarah Whittle, Murat Yucel, Christos Pantelis, Soon-Hyung Yi

Journal article  |  2013  |  Behavioral and Brain Functions