James McCaw

Enhanced viral infectivity and reduced interferon production are associated with high pathogenicity for influenza viruses.

Ke Li, James M McCaw, Pengxing Cao

Journal article  |  2023  |  PLoS Comput Biol

Epidemiological and clinical evidence indicates that humans infected with the 1918 pandemic H1N1 influenza virus and highly pathog..

A modelling approach to estimate the transmissibility of SARS-CoV-2 during periods of high, low, and zero case incidence.

Nick Golding, David J Price, Gerard Ryan, Jodie McVernon, James M McCaw, Freya M Shearer

Journal article  |  2023  |  Elife

Against a backdrop of widespread global transmission, a number of countries have successfully brought large outbreaks of COVID-19 ..

Real-time analysis of hospital length of stay in a mixed SARS-CoV-2 Omicron and Delta epidemic in New South Wales, Australia

Ruarai JJ Tobin, James GG Wood, Duleepa Jayasundara, Grant Sara, Camelia RR Walker, Genevieve EE Martin, James MM McCaw, Freya MM Shearer, David JJ Price

Journal article  |  2023  |  BMC INFECTIOUS DISEASES

BACKGROUND: The distribution of the duration that clinical cases of COVID-19 occupy hospital beds (the 'length of stay') is a key ..

Stochastic Modeling of Within-Host Dynamics of Plasmodium Falciparum

Xiao Sun, James M McCaw, Pengxing Cao

Journal article  |  2022  |  MATHEMATICS

Malaria remains a major public health burden in South-East Asia and Africa. Mathematical models of within-host infection dynamics ..

A Multiscale Mathematical Model of Plasmodium Vivax Transmission

Md Nurul Anwar, Roslyn I Hickson, Somya Mehra, James M McCaw, Jennifer A Flegg

Journal article  |  2022  |  BULLETIN OF MATHEMATICAL BIOLOGY

Malaria is caused by Plasmodium parasites which are transmitted to humans by the bite of an infected Anopheles mosquito. Plasmodiu..

COVID-19 in low-tolerance border quarantine systems: Impact of the Delta variant of SARS-CoV-2

Cameron Zachreson, Freya M Shearer, David J Price, Michael J Lydeamore, Jodie McVernon, James McCaw, Nicholas Geard

Journal article  |  2022  |  SCIENCE ADVANCES

In controlling transmission of coronavirus disease 2019 (COVID-19), the effectiveness of border quarantine strategies is a key con..

Hypnozoite dynamics for Plasmodium vivax malaria: The epidemiological effects of radical cure.

Somya Mehra, Eva Stadler, David Khoury, James M McCaw, Jennifer A Flegg

Journal article  |  2022  |  J Theor Biol

Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is a major cause of human malaria beyond su..

Rapid assessment of the risk of SARS-CoV-2 importation: case study and lessons learned

Freya M Shearer, James Walker, Nefel Tellioglu, James M McCaw, Jodie McVernon, Andrew Black, Nicholas Geard

Journal article  |  2022  |  EPIDEMICS

During the early stages of an emerging disease outbreak, governments are required to make critical decisions on how to respond, de..

From Climate Change to Pandemics: Decision Science Can Help Scientists Have Impact

Christopher M Baker, Patricia T Campbell, Iadine Chades, Angela J Dean, Susan M Hester, Matthew H Holden, James M McCaw, Jodie McVernon, Robert Moss, Freya M Shearer, Hugh P Possingham

Journal article  |  2022  |  FRONTIERS IN ECOLOGY AND EVOLUTION

Scientific knowledge and advances are a cornerstone of modern society. They improve our understanding of the world we live in and ..

Estimation of the probability of epidemic fade-out from multiple outbreak data

Punya Alahakoon, James M McCaw, Peter G Taylor

Journal article  |  2022  |  EPIDEMICS

Deterministic epidemic models that allow for replenishment of susceptibles typically display damped oscillatory behaviour. If the ..