James McCaw

Influencing public health policy with data-informed mathematical models of infectious diseases: Recent developments and new challenges.

Amani Alahmadi, Sarah Belet, Andrew Black, Deborah Cromer, Jennifer A Flegg, Thomas House, Pavithra Jayasundara, Jonathan M Keith, James M McCaw, Robert Moss, Joshua V Ross, Freya M Shearer, Sai Thein Than Tun, James Walker, Lisa White, Jason M Whyte, Ada WC Yan, Alexander E Zarebski

Journal article  |  2020  |  Epidemics

Modern data and computational resources, coupled with algorithmic and theoretical advances to exploit these, allow disease dynamic..

An Activation-Clearance Model for Plasmodium vivax Malaria

Somya Mehra, James M McCaw, Mark B Flegg, Peter G Taylor, Jennifer A Flegg

Journal article  |  2020  |  Bulletin of Mathematical Biology

Malaria is an infectious disease with an immense global health burden. Plasmodium vivax is the most geographically widespread spec..

Infectious disease pandemic planning and response: Incorporating decision analysis.

Freya M Shearer, Robert Moss, Jodie McVernon, Joshua V Ross, James M McCaw

Journal article  |  2020  |  PLOS Medicine

Freya Shearer and co-authors discuss the use of decision analysis in planning for infectious disease pandemics.

Coordinating the real-time use of global influenza activity data for better public health planning

Matthew Biggerstaff, Fredrick Scott Dahlgren, Julia Fitzner, Dylan George, Aspen Hammond, Ian Hall, David Haw, Natsuko Imai, Michael A Johansson, Sarah Kramer, James M McCaw, Robert Moss, Richard Pebody, Jonathan M Read, Carrie Reed, Nicholas G Reich, Steven Riley, Katelijn Vandemaele, Cecile Viboud, Joseph T Wu

Journal article  |  2019  |  Influenza and Other Respiratory Viruses

Modeling the dynamics of Plasmodium falciparum gametocytes in humans during malaria infection

Pengxing Cao, Katharine A Collins, Sophie Zaloumis, Thanaporn Wattanakul, Joel Tarning, Julie A Simpson, James McCarthy, James M McCaw

Journal article  |  2019  |  eLife

Renewed efforts to eliminate malaria have highlighted the potential to interrupt human-to-mosquito transmission - a process mediat..

A sub-exponential branching process to study early epidemic dynamics with application to Ebola

Alexander Zarebski, Robert Moss, James McCaw

Journal article  |  2019

Abstract Exponential growth is a mathematically convenient model for the early stages of an outbreak of an infectious disease. How..

Anatomy of a seasonal influenza epidemic forecast

Robert Moss, Alexander E Zarebski, Peter Dawson, Lucinda J Franklin, Frances A Birrell, James M McCaw

Journal article  |  2019  |  Communicable Diseases Intelligence

A biological model of scabies infection dynamics and treatment informs mass drug administration strategies to increase the likelihood of elimination

MJ Lydeamore, PT Campbell, DG Regan, SYC Tong, RM Andrews, AC Steer, L Romani, JM Kaldor, J McVernon, JM McCaw

Journal article  |  2019  |  Mathematical Biosciences

A simple influenza model with complicated dynamics

MG Roberts, RI Hickson, JM McCaw, L Talarmain

Journal article  |  2019  |  Journal of Mathematical Biology

Accounting for Healthcare-Seeking Behaviours and Testing Practices in Real-Time Influenza Forecasts

R Moss, Alexander E Zarebski, Sandra J Carlson, James M McCaw

Journal article  |  2019  |  Tropical Medicine and Infectious Disease

For diseases such as influenza, where the majority of infected persons experience mild (if any) symptoms, surveillance systems are..

Sequential infection experiments for quantifying innate and adaptive immunity during influenza infection

Ada WC Yan, Sophie G Zaloumis, Julie A Simpson, James M McCaw

Journal article  |  2019  |  PLOS Computational Biology

MODELLING HYPOTHESIZED INTERACTIONS OF PLASMODIUM FALCIPARUM AND P. VIVAX

Roslyn Hickson, Ricardo Aguas, Angela Devine, James McCaw, Lisa White

Conference Proceedings  |  2019  |  AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE

Predicting the Outcomes of New Short-Course Regimens for Multidrug-Resistant Tuberculosis Using Intrahost and Pharmacokinetic-Pharmacodynamic Modeling

Tan N Doan, Pengxing Cao, Theophilus I Emeto, James M Mccaw, Emma S McBryde

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

In Silico Investigation of the Decline in Clinical Efficacy of Artemisinin Combination Therapies Due to Increasing Artemisinin and Partner Drug Resistance

Sophie G Zaloumis, Pengxing Cao, Saber Dini, Miles P Davenport, Deborah Cromer, David S Khoury, Freya JI Fowkes, James M McCaw, Julie A Simpson

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Characterization of Influenza B Virus Variants with Reduced Neuraminidase Inhibitor Susceptibility

R Farrukee, AE Zarebski, JM McCaw, JD Bloom, PC Reading, AC Hurt

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling

Saber Dini, Sophie Zaloumis, Pengxing Cao, Ric N Price, Freya J Fowkes, E Rob W van der Pluijm, James M McCaw, Julie A Simpson

Journal article  |  2018  |  Antimicrobial Agents and Chemotherapy

Within-host modeling of blood-stage malaria

David S Khoury, Rosemary Aogo, Georges Randriafanomezantsoa-Radohery, James M McCaw, Julie A Simpson, James S McCarthy, Ashraful Haque, Deborah Cromer, Miles P Davenport

Journal article  |  2018  |  Immunological Reviews

The distribution of the time taken for an epidemic to spread between two communities

Ada WC Yan, Andrew J Black, James M McCaw, Nicolas Rebuli, Joshua Ross, Annalisa J Swan, Roslyn Hickson

Journal article  |  2018  |  Mathematical Biosciences

Investigating Viral Interference Between Influenza A Virus and Human Respiratory Syncytial Virus in a Ferret Model of Infection

Kok Fei Chan, Louise A Carolan, Daniil Korenkov, Julian Druce, James McCaw, Patrick C Reading, Ian G Barr, Karen L Laurie

Journal article  |  2018  |  The Journal of Infectious Diseases

Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern Australia

MJ Lydeamore, PT Campbell, W Cuningham, RM Andrews, T Kearns, D Clucas, R Gundjirryirr Dhurrkay, J Carapetis, SYC Tong, JM McCaw, J McVernon

Journal article  |  2018  |  Epidemiology and Infection

Clonally diverse CD38( )HLA-DR( )CD8( ) T cells persist during fatal H7N9 disease

Zhongfang Wang, Lingyan Zhu, Thi HO Nguyen, Yanmin Wan, Sneha Sant, Sergio M Quinones-Parra, Jeremy Chase Crawford, Auda A Eltahla, Simone Rizzetto, Rowena A Bull, Chenli Qiu, Marios Koutsakos, E Bridie Clemens, Liyen Loh, Tianyue Chen, Lu Liu, Pengxing Cao, Yanqin Ren, Lukasz Kedzierski, Tom Kotsimbos, et al.

Journal article  |  2018  |  NATURE COMMUNICATIONS

Evidence for Viral Interference and Cross-reactive Protective Immunity Between Influenza B Virus Lineages

Karen L Laurie, William Horman, Louise A Carolan, Kok Fei Chan, Daniel Layton, Andrew Bean, Dhanasekaran Vijaykrishna, Patrick C Reading, James M Mccaw, Ian G Barr

Journal article  |  2018  |  The Journal of Infectious Diseases

Epidemic forecasts as a tool for public health: interpretation and (re)calibration

Robert Moss, James E Fielding, Lucinda J Franklin, Nicola Stephens, Jodie McVernon, Peter Dawson, James M McCaw

Journal article  |  2018  |  AUSTRALIAN AND NEW ZEALAND JOURNAL OF PUBLIC HEALTH

Infection-acquired versus vaccine-acquired immunity in an SIRWS model

Tiffany Leung, Patricia T Campbell, Barry D Hughes, Federico Frascoli, James M McCaw

Journal article  |  2018  |  Infectious Disease Modelling

In some disease systems, the process of waning immunity can be subtle, involving a complex relationship between the duration of im..

A Dynamic Stress Model Explains the Delayed Drug Effect in Artemisinin Treatment of Plasmodium falciparum

Pengxing Cao, Nectarios Klonis, Sophie Zaloumis, Con Dogovski, Stanley C Xie, Sompob Saralamba, Lisa J White, Freya JI Fowkes, Leann Tilley, Julie A Simpson, James M McCaw

Journal article  |  2017  |  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection

Pengxing Cao, Nectarios Klonis, Sophie Zaloumis, David S Khoury, Deborah Cromer, Miles P Davenport, Leann Tilley, Julie A Simpson, James M McCaw

Journal article  |  2017  |  Journal of Theoretical Biology

The Mechanisms for Within-Host Influenza Virus Control Affect Model-Based Assessment and Prediction of Antiviral Treatment

Pengxing Cao, James M McCaw

Journal article  |  2017  |  VIRUSES-BASEL

Influenza as a trigger for cardiovascular disease: An investigation of serotype, subtype and geographic location

DC Pearce, JM McCaw, J McVernon, JD Mathews

Journal article  |  2017  |  Environmental Research

Characterising pandemic severity and transmissibility from data collected during first few hundred studies

Andrew J Black, Nicholas Geard, James M McCaw, Jodie McVernon, Joshua V Ross

Journal article  |  2017  |  EPIDEMICS

Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host (vol 413, pg 34, 2017)

Ada WC Yan, Pengxing Cao, Jane M Heffernan, Jodie McVernon, Kylie M Quinn, Nicole L La Gruta, Karen L Laurie, James M Mccaw

Journal article  |  2017  |  Journal of Theoretical Biology

Model selection for seasonal influenza forecasting.

Alexander E Zarebski, Peter Dawson, James M McCaw, Robert Moss

Journal article  |  2017  |  Infect Dis Model

Epidemics of seasonal influenza inflict a huge burden in temperate climes such as Melbourne (Australia) where there is also signif..

Turnover of Village Chickens Undermines Vaccine Coverage to Control HPAI H5N1

JP Villanueva-Cabezas, PT Campbell, JM McCaw, PA Durr, J McVernon

Journal article  |  2017  |  Zoonoses and Public Health

Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host

Ada WC Yan, Pengxing Cao, Jane M Heffernan, Jodie McVernon, Kylie M Quinn, Nicole L La Gruta, Karen L Laurie, James M McCaw

Journal article  |  2017  |  Journal of Theoretical Biology

Retrospective forecasting of the 2010-2014 Melbourne influenza seasons using multiple surveillance systems

R Moss, A Zarebski, P Dawson, JM McCaw

Journal article  |  2017  |  EPIDEMIOLOGY AND INFECTION

On the Role of CD8( ) T Cells in Determining Recovery Time from Influenza Virus Infection

Pengxing Cao, Zhongfang Wang, Ada WC Yan, Jodie McVernon, Jianqing Xu, Jane M Heffernan, Katherine Kedzierska, James M McCaw

Journal article  |  2016  |  FRONTIERS IN IMMUNOLOGY

Periodic solutions in an SIRWS model with immune boosting and cross-immunity

Tiffany Leung, Barry D Hughes, Federico Frascoli, James M McCaw

Journal article  |  2016  |  Journal of Theoretical Biology

Reducing disease burden in an influenza pandemic by targeted delivery of neuraminidase inhibitors: mathematical models in the Australian context

Robert Moss, James M McCaw, Allen C Cheng, Aeron C Hurt, Jodie McVernon

Journal article  |  2016  |  BMC INFECTIOUS DISEASES

High Conservation Level of CD8( ) T Cell Immunogenic Regions Within an Unusual H1N2 Human Influenza Variant

Naomi Komadina, Sergio M Quinones-Parra, Katherine Kedzierska, James M McCaw, Anne Kelso, Karin Leder, Jodie McVernon

Journal article  |  2016  |  JOURNAL OF MEDICAL VIROLOGY

On the extinction probability in models of within-host infection: the role of latency and immunity

Ada WC Yan, Pengxing Cao, James M McCaw

Journal article  |  2016  |  Journal of Mathematical Biology

Model-Informed Risk Assessment and Decision Making for an Emerging Infectious Disease in the Asia-Pacific Region

Robert Moss, Roslyn I Hickson, Jodie McVernon, James M McCaw, Krishna Hort, Jim Black, John R Madden, Nhi H Tran, Emma S McBryde, Nicholas Geard

Journal article  |  2016  |  PLOS NEGLECTED TROPICAL DISEASES

Comparison of the Exposure Time Dependence of the Activities of Synthetic Ozonide Antimalarials and Dihydroartemisinin against K13 Wild-Type and Mutant Plasmodium falciparum Strains

Tuo Yang, Stanley C Xie, Pengxing Cao, Carlo Giannangelo, James McCaw, Darren J Creek, Susan A Charman, Nectarios Klonis, Leann Tilley

Journal article  |  2016  |  ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Forecasting influenza outbreak dynamics in Melbourne from Internet search query surveillance data

Robert Moss, Alexander Zarebski, Peter Dawson, James M McCaw

Journal article  |  2016  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Heightened self-reactivity associated with selective survival, but not expansion, of naive virus-specific CD8( ) T cells in aged mice

Kylie M Quinn, Sophie G Zaloumis, Tania Cukalac, Wan-Ting Kan, Xavier YX Sng, Michiko Mirams, Katherine A Watson, James M McCaw, Peter C Doherty, Paul G Thomas, Andreas Handel, Nicole L La Gruta

Journal article  |  2016  |  Proceedings of the National Academy of Sciences

Parasite Strain, Host Immunity, and Circulating Blood Cells with Dead Parasites: Why Predicting Malaria Parasite Clearance Is Not a Simple Task

J Simpson, J McCaw, FJ Fowkes

Journal article  |  2016  |  Antimicrobial Agents and Chemotherapy

Mathematical modelling for the development, monitoring and evaluation of intervention strategies for infectious diseases.

James McCaw

Journal article  |  2016  |  Pathology

The effects of demographic change on disease transmission and vaccine impact in a household structured population

Nicholas Geard, Kathryn Glass, James M McCaw, Emma S McBryde, Kevin B Korb, Matt J Keeling, Jodie McVernon

Journal article  |  2015  |  EPIDEMICS

Interval Between Infections and Viral Hierarchy Are Determinants of Viral Interference Following Influenza Virus Infection in a Ferret Model

Karen L Laurie, Teagan A Guarnaccia, Louise A Carolan, Ada WC Yan, Malet Aban, Stephen Petrie, Pengxing Cao, Jane M Heffernan, Jodie McVernon, Jennifer Mosse, Anne Kelso, James M Mccaw, Ian G Barr

Journal article  |  2015  |  JOURNAL OF INFECTIOUS DISEASES

Social encounter profiles of greater Melbourne residents, by location - a telephone survey

David A Rolls, Nicholas L Geard, Deborah J Warr, Paula M Nathan, Garry L Robins, Philippa E Pattison, James M McCaw, Jodie McVernon

Journal article  |  2015  |  BMC INFECTIOUS DISEASES

A new approach to estimating trends in chlamydia incidence

Hammad Ali, Ewan Cameron, Christopher C Drovandi, James M Mccaw, Rebecca J Guy, Melanie Middleton, Carol El-Hayek, Jane S Hocking, John M Kaldor, Basil Donovan, David P Wilson

Journal article  |  2015  |  Sexually Transmitted Infections

Defining long-term drivers of pertussis resurgence, and optimal vaccine control strategies

Patricia Therese Campbell, James Matthew McCaw, Peter McIntyre, Jodie McVernon

Journal article  |  2015  |  Vaccine

Quantifying relative within-host replication fitness in influenza virus competition experiments

Stephen M Petrie, Jeff Butler, Ian G Barr, Jodie McVernon, Aeron C Hurt, James M McCaw

Journal article  |  2015  |  JOURNAL OF THEORETICAL BIOLOGY

Factors associated with transmission of influenza-like illness in a cohort of households containing multiple children

Chelsea R Brown, James M McCaw, Emily J Fairmaid, Lorena E Brown, Karin Leder, Martha Sinclair, Jodie McVernon

Journal article  |  2015  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Innate Immunity and the Inter-exposure Interval Determine the Dynamics of Secondary Influenza Virus Infection and Explain Observed Viral Hierarchies

Pengxing Cao, Ada WC Yan, Jane M Heffernan, Stephen Petrie, Robert G Moss, Louise A Carolan, Teagan A Guarnaccia, Anne Kelso, Ian G Barr, Jodie McVernon, Karen L Laurie, James M McCaw

Journal article  |  2015  |  PLOS COMPUTATIONAL BIOLOGY

Targeting the Cell Stress Response of Plasmodium falciparum to Overcome Artemisinin Resistance

Con Dogovski, Stanley C Xie, Gaetan Burgio, Jess Bridgford, Sachel Mok, James M McCaw, Kesinee Chotivanich, Shannon Kenny, Nina Gnaedig, Judith Straimer, Zbynek Bozdech, David A Fidock, Julie A Simpson, Arjen M Dondorp, Simon Foote, Nectarios Klonis, Leann Tilley

Journal article  |  2015  |  PLOS BIOLOGY

Prior Population Immunity Reduces the Expected Impact of CTL-Inducing Vaccines for Pandemic Influenza Control

Kirsty J Bolton, James M McCaw, Lorena Brown, David Jackson, Katherine Kedzierska, Jodie McVernon

Journal article  |  2015  |  PLOS ONE

Pertussis models to inform vaccine policy

Patricia T Campbell, James M McCaw, Jodie McVernon

Journal article  |  2015  |  HUMAN VACCINES & IMMUNOTHERAPEUTICS

Quantifying differences in the epidemic curves from three influenza surveillance systems: a nonlinear regression analysis

EG Thomas, JM McCaw, HA Kelly, KA Grant, J McVernon

Journal article  |  2015  |  Epidemiology and Infection

The dynamical consequences of seasonal forcing, immune boosting and demographic change in a model of disease transmission

Mathew P Dafilis, Federico Frascoli, Jodie McVernon, Jane M Heffernan, James M McCaw

Journal article  |  2014  |  JOURNAL OF THEORETICAL BIOLOGY

Population pharmacokinetics of intravenous artesunate: a pooled analysis of individual data from patients with severe malaria.

SG Zaloumis, J Tarning, S Krishna, RN Price, NJ White, TME Davis, JM McCaw, P Olliaro, RJ Maude, P Kremsner, A Dondorp, M Gomes, K Barnes, JA Simpson

Journal article  |  2014  |  CPT Pharmacometrics Syst Pharmacol

There are ~660,000 deaths from severe malaria each year. Intravenous artesunate (i.v. ARS) is the first-line treatment in adults a..

Population Pharmacokinetics of Intravenous Artesunate: A Pooled Analysis of Individual Data From Patients With Severe Malaria.

SG Zaloumis, J Tarning, S Krishna, RN Price, NJ White, TME Davis, JM McCaw, P Olliaro, RJ Maude, P Kremsner, A Dondorp, M Gomes, K Barnes, JA Simpson

Journal article  |  2014  |  CPT: pharmacometrics & systems pharmacology

There are ~660,000 deaths from severe malaria each year. Intravenous artesunate (i.v. ARS) is the first-line treatment in adults a..

Dynamical crises, multistability and the influence of the duration of immunity in a seasonally-forced model of disease transmission

Mathew P Dafilis, Federico Frascoli, Jodie McVernon, Jane M Heffernan, James M McCaw

Journal article  |  2014  |  THEORETICAL BIOLOGY AND MEDICAL MODELLING

Making the Most of Clinical Data: Reviewing the Role of Pharmacokinetic-Pharmacodynamic Models of Anti-malarial Drugs

Julie A Simpson, Sophie Zaloumis, Alysha M DeLivera, Ric N Price, James M McCaw

Journal article  |  2014  |  AAPS JOURNAL

Evaluation of oseltamivir prophylaxis regimens for reducing influenza virus infection, transmission and disease severity in a ferret model of household contact

Ding Yuan Oh, Sue Lowther, James M McCaw, Sheena G Sullivan, Sook-Kwan Leang, Jessica Haining, Rachel Arkinstall, Anne Kelso, Jodie Mcvernon, Ian G Barr, Deborah Middleton, Aeron C Hurt

Journal article  |  2014  |  JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

The influence of changing host immunity on 1918-19 pandemic dynamics

KJ Bolton, JM McCaw, J McVernon, JD Mathews

Journal article  |  2014  |  EPIDEMICS

Estimating the Fitness Advantage Conferred by Permissive Neuraminidase Mutations in Recent Oseltamivir-Resistant A(H1N1) pdm09 Influenza Viruses

Jeff Butler, Kathryn A Hooper, Stephen Petrie, Raphael Lee, Sebastian Maurer-Stroh, Lucia Reh, Teagan Guarnaccia, Chantal Baas, Lumin Xue, Sophie Vitesnik, Sook-Kwan Leang, Jodie McVernon, Anne Kelso, Ian G Barr, James M McCaw, Jesse D Bloom, Aeron C Hurt

Journal article  |  2014  |  PLOS PATHOGENS

Pandemic controllability: a concept to guide a proportionate and flexible operational response to future influenza pandemics

JM McCaw, K Glass, GN Mercer, J McVernon

Journal article  |  2014  |  Journal of Public Health

Faculty Opinions recommendation of Does homologous reinfection drive multiple-wave influenza outbreaks? Accounting for immunodynamics in epidemiological models.

Lewi Stone, James McCaw

Dataset  |  2014

Faculty Opinions recommendation of Inferring the causes of the three waves of the 1918 influenza pandemic in England and Wales.

Lewi Stone, James McCaw

Dataset  |  2013

Reducing Uncertainty in Within-Host Parameter Estimates of Influenza Infection by Measuring Both Infectious and Total Viral Load

Stephen M Petrie, Teagan Guarnaccia, Karen L Laurie, Aeron C Hurt, Jodie McVernon, James M McCaw

Journal article  |  2013  |  PLOS ONE

Antigenic Drift of the Pandemic 2009 A(H1N1) Influenza Virus in a Ferret Model

Teagan Guarnaccia, Louise A Carolan, Sebastian Maurer-Stroh, Raphael TC Lee, Emma Job, Patrick C Reading, Stephen Petrie, James M McCaw, Jodie McVernon, Aeron C Hurt, Anne Kelso, Jennifer Mosse, Ian G Barr, Karen L Laurie

Journal article  |  2013  |  PLOS PATHOGENS

Virus detection and its association with symptoms during influenza-like illness in a sample of healthy adults enrolled in a randomised controlled vaccine trial

Peter F Howard, James M McCaw, Peter C Richmond, Michael Nissen, Theo Sloots, Stephen B Lambert, Michael Lai, Michael Greenberg, Terry Nolan, Jodie McVernon

Journal article  |  2013  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Altered temporal response of malaria parasites determines differential sensitivity to artemisinin

Nectarios Klonis, Stanley C Xie, James M McCaw, Maria P Crespo-Ortiz, Sophie G Zaloumis, Julie A Simpson, Leann Tilley

Journal article  |  2013  |  Proceedings of the National Academy of Sciences of the United States of America

Synthetic Population Dynamics: A Model of Household Demography

Nicholas Geard, James M McCaw, Alan Dorin, Kevin B Korb, Jodie McVernon

Journal article  |  2013  |  Journal of Artifical Societies and Social Simulation

Household transmission of respiratory viruses - assessment of viral, individual and household characteristics in a population study of healthy Australian adults

James M McCaw, Peter F Howard, Peter C Richmond, Michael Nissen, Theo Sloots, Stephen B Lambert, Michael Lai, Michael Greenberg, Terry Nolan, Jodie McVernon

Journal article  |  2012  |  BMC Infectious Diseases

Drivers and consequences of influenza antiviral resistant-strain emergence in a capacity-constrained pandemic response

Mathew P Dafilis, Robert Moss, Jodie McVernon, James McCaw

Journal article  |  2012  |  EPIDEMICS

THE INFLUENCE OF INCREASING LIFE EXPECTANCY ON THE DYNAMICS OF SIRS SYSTEMS WITH IMMUNE BOOSTING

MP Dafilis, F Frascoli, JG Wood, JM Mccaw

Journal article  |  2012  |  The ANZIAM Journal

Assessing the utility of an anti-malarial pharmacokinetic-pharmacodynamic model for aiding drug clinical development

Sophie Zaloumis, Andrew Humberstone, Susan A Charman, Ric N Price, Joerg Moehrle, Javier Gamo-Benito, James McCaw, Kris M Jamsen, Katherine Smith, Julie A Simpson

Journal article  |  2012  |  Malaria Journal

Application of a case-control study design to investigate genotypic signatures of HIV-1 transmission

Talia M Mota, John M Murray, Rob J Center, Damian FJ Purcell, James M McCaw

Journal article  |  2012  |  Retrovirology

Likely effectiveness of pharmaceutical and non-pharmaceutical interventions for mitigating influenza virus transmission in Mongolia

KJ Bolton, JM McCaw, R Moss, RS Morris, S Wang, A Burma, B Darma, D Narangerel, P Nymadawa, J McVernon

Journal article  |  2012  |  BULLETIN OF THE WORLD HEALTH ORGANIZATION

Influence of Contact Definitions in Assessment of the Relative Importance of Social Settings in Disease Transmission Risk

Kirsty J Bolton, James M McCaw, Kristian Forbes, Paula Nathan, Garry Robins, Philippa Pattison, Terry Nolan, Jodie McVernon

Journal article  |  2012  |  PLOS ONE

H1N1 influenza and the Australian macroeconomy

George Verikios, James M McCaw, Jodie McVernon, Anthony H Harris

Journal article  |  2012  |  Journal of the Asia Pacific Economy

Incorporating population dynamics into household models of infectious disease transmission

K Glass, JM McCaw, J McVernon

Journal article  |  2011  |  Epidemics

Proof of principle for an immunological model to explain mortality variations over the three waves of the 1918-1919 pandemic

John D Mathews, Dora C Pearce, Kirsty J Bolton, Jodie McVernon, James M McCaw

Conference Proceedings  |  2011  |  Influenza and Other Respiratory Viruses

A decision support tool for evaluating the impact of a diagnostic-capacity and antiviral-delivery constrained intervention strategy on an influenza pandemic

James M McCaw, Robert Moss, Jodie McVernon

Conference Proceedings  |  2011  |  Influenza and Other Respiratory Viruses

Exploring alternate immune hypotheses in dynamical models of the 1918-1919 influenza pandemic

Kirsty J Bolton, James M McCaw, Jodie McVernon, John D Mathews

Conference Proceedings  |  2011  |  Influenza and Other Respiratory Viruses

A Mathematical Framework for Estimating Pathogen Transmission Fitness and Inoculum Size Using Data from a Competitive Mixtures Animal Model

James M McCaw, Nimalan Arinaminpathy, Aeron C Hurt, Jodie McVernon, Angela R McLean

Journal article  |  2011  |  PLoS Computational Biology

Understanding mortality in the 1918-1919 influenza pandemic in England and Wales

Dora C Pearce, Paul K Pallaghy, James M McCaw, Jodie McVernon, John D Mathews

Journal article  |  2011  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Diagnosis and Antiviral Intervention Strategies for Mitigating an Influenza Epidemic

Robert Moss, James M McCaw, Jodie McVernon

Journal article  |  2011  |  PLOS ONE

Assessing the Viral Fitness of Oseltamivir-Resistant Influenza Viruses in Ferrets, Using a Competitive-Mixtures Model

Aeron C Hurt, Siti Sarah Nor'e, James M McCaw, Helen R Fryer, Jennifer Mosse, Angela R McLean, Ian G Barr

Journal article  |  2010  |  Journal of Virology

Comparison of three methods for ascertainment of contact information relevant to respiratory pathogen transmission in encounter networks

James M McCaw, Kristian Forbes, Paula M Nathan, Philippa E Pattison, Garry L Robins, Terence M Nolan, Jodie McVernon

Journal article  |  2010  |  BMC Infectious Diseases

Prior immunity helps to explain wave-like behaviour of pandemic influenza in 1918-9

John D Mathews, Emma S McBryde, Jodie McVernon, Paul K Pallaghy, James M McCaw

Journal article  |  2010  |  BMC Infectious Diseases

Modelling strategic use of the national antiviral stockpile during the CONTAIN and SUSTAIN phases of an Australian pandemic influenza response

Jodie McVernon, James M McCaw, Terence M Nolan

Journal article  |  2010  |  Australian and New Zealand Journal of Public Health

Influenza: Accounting for Prior Immunity

James M McCaw, Jodie McVernon, Emma S McBryde, John D Mathews

Journal article  |  2009  |  Science

Understanding Australia's influenza pandemic policy on the strategic use of the antiviral drug stockpile

James M McCaw, James G Wood, Emma S McBryde, Terry M Nolan, Joseph T Wu, Marc Lipsitch, Jodie McVernon

Journal article  |  2009  |  Medical Journal of Australia

Understanding influenza transmission, immunity and pandemic threats

John D Mathews, Joanne M Chesson, James M McCaw, Jodie McVernon

Journal article  |  2009  |  INFLUENZA AND OTHER RESPIRATORY VIRUSES

Optimal Dosing and Dynamic Distribution of Vaccines in an Influenza Pandemic

James Wood, James McCaw, Niels Becker, Terry Nolan, C Raina MacIntyre

Journal article  |  2009  |  American Journal of Epidemiology

A Mathematical Model to Determine Optimal Dosing and Dynamic Distribution of Pandemic Influenza Vaccines

JG Wood, J Mccaw, N Becker, T Nolan, CR MacIntyre

Conference Proceedings  |  2008  |  International Journal of Infectious Diseases

Impact of Emerging Antiviral Drug Resistance on Influenza Containment and Spread: Influence of Subclinical Infection and Strategic Use of a Stockpile Containing One or Two Drugs

James M McCaw, James G Wood, Christopher T McCaw, Jodie McVernon

Journal article  |  2008  |  PLoS One

A Biological Model for Influenza Transmission: Pandemic Planning Implications of Asymptomatic Infection and Immunity

John D Mathews, Christopher T McCaw, Jodie McVernon, Emma S McBryde, James M McCaw

Journal article  |  2007  |  PLOS ONE

Prophylaxis or treatment? Optimal use of an antiviral stockpile during an influenza pandemic

James M McCaw, Jodie McVernon

Journal article  |  2007  |  Mathematical Biosciences

On the continuous spectral component of the Floquet operator for a periodically kicked quantum system

J McCaw, BHJ McKellar

Journal article  |  2005  |  Journal of Mathematical Physics

Pure point spectrum for the time evolution of a periodically rank-N kicked Hamiltonian

J McCaw, BHJ McKeller

Journal article  |  2005  |  Journal of Mathematical Physics

Quantum Chaos: Spectral Analysis of Floquet Operators

J MCCAW

Book  |  2005