Sant-Rayn Pasricha

Safety of rapid injection of undiluted ferric carboxymaltose to patients with iron-deficiency anaemia: a Phase II single-arm study

Sant-Rayn Pasricha, Michael Gilbertson, Tishya Indran, Ashwini Bennett, Matthew van Dam, Elizabeth Coughlin, Anouk Dev, Sanjeev Chunilal, Stephen Opat

Journal article  |  2021  |  INTERNAL MEDICINE JOURNAL

BACKGROUND: Ferric carboxymaltose is increasingly utilised to treat iron deficiency and is usually diluted in saline and administe..

Immediate impact of stay-at-home orders to control COVID-19 transmission on socioeconomic conditions, food insecurity, mental health, and intimate partner violence in Bangladeshi women and their families: an interrupted time series

Jena Derakhshani Hamadani, Mohammed Imrul Hasan, Andrew J Baldi, Sheikh Jamal Hossain, Shamima Shiraji, Mohammad Saiful Alam Bhuiyan, Syeda-Fardina Mehrin, Jane Fisher, Fahmida Tofail, SM Mulk Uddin Tipu, Sally Grantham-McGregor, Beverley-Ann Biggs, Sabine Braat, Sant-Rayn Pasricha

Journal article  |  2020  |  LANCET GLOBAL HEALTH

BACKGROUND: Stay-at-home orders (lockdowns) have been deployed globally to control COVID-19 transmission, and might impair economi..

Anemia and water, sanitation, and hygiene (WASH)-is there really a link?

Andrew J Baldi, Danielle Clucas, Sant-Rayn Pasricha

Journal article  |  2020  |  AMERICAN JOURNAL OF CLINICAL NUTRITION

Antibodies against the erythroferrone N-terminal domain prevent hepcidin suppression and ameliorate murine thalassemia

Joao Arezes, Niall Foy, Kirsty McHugh, Doris Quinkert, Susan Benard, Anagha Sawant, Joe N Frost, Andrew E Armitage, Sant-Rayn Pasricha, Pei Jin Lim, May S Tam, Edward Lavallie, Debra D Pittman, Orla Cunningham, Matthew Lambert, John E Murphy, Simon J Draper, Reema Jasuja, Hal Drakesmith

Journal article  |  2020  |  BLOOD

Erythroferrone (ERFE) is produced by erythroblasts in response to erythropoietin (EPO) and acts in the liver to prevent hepcidin s..

Balancing Safety and Potential for Impact in Universal Iron Interventions

Andrew J Baldi, Leila M Larson, Sant-Rayn Pasricha

Journal article  |  2020  |  GLOBAL LANDSCAPE OF NUTRITION CHALLENGES IN INFANTS AND CHILDREN

Almost 300 million children under 5 years of age are anemic worldwide. International policymakers recommend universal distribution..

Changes in micronutrient and inflammation serum biomarker concentrations after a norovirus human challenge

Anne M Williams, Chandresh N Ladva, Juan S Leon, Ben A Lopman, Vin Tangpricha, Ralph D Whitehead, Andrew E Armitage, Katherine Wray, Alireza Morovat, Sant-Rayn Pasricha, David Thurnham, Sherry A Tanumihardjo, Setti Shahab-Ferdows, Lindsay Allen, Rafael C Flores-Ayala, Parminder S Suchdev

Journal article  |  2019  |  AMERICAN JOURNAL OF CLINICAL NUTRITION

BACKGROUND: To accurately assess micronutrient status, it is necessary to characterize the effects of inflammation and the acute-p..

Hepcidin-guided screen-and-treat interventions against iron-deficiency anaemia in pregnancy: a randomised controlled trial in The Gambia

Amat Bah, Abdul Khalie Muhammad, Rita Wegmuller, Hans Verhoef, Morgan M Goheen, Saikou Sanyang, Ebrima Danso, Ebrima A Sise, Sant-Rayn Pasricha, Andrew E Armitage, Hal Drakesmith, James H Cross, Sophie E Moore, Carla Cerami, Andrew M Prentice

Journal article  |  2019  |  LANCET GLOBAL HEALTH

BACKGROUND: WHO recommends daily iron supplementation for pregnant women, but adherence is poor because of side-effects, effective..

Transcriptomic profiling of the myeloma bone-lining niche reveals BMP signalling inhibition to improve bone disease

Sarah Gooding, Sam WZ Olechnowicz, Emma Morris, Andrew E Armitage, Joao Arezes, Joe Frost, Emmanouela Repapi, James R Edwards, Neil Ashley, Craig Waugh, Nicola Gray, Erik Martinez-Hackert, Pei Jin Lim, Sant-Rayn Pasricha, Helen Knowles, Adam J Mead, Karthik Ramasamy, Hal Drakesmith, Claire M Edwards

Journal article  |  2019  |  NATURE COMMUNICATIONS

Multiple myeloma is an incurable, bone marrow-dwelling malignancy that disrupts bone homeostasis causing skeletal damage and pain...

Use and interpretation of hemoglobin concentrations for assessing anemia status in individuals and populations: results from a WHO technical meeting

Maria Nieves Garcia-Casal, Sant-Rayn Pasricha, Andrea J Sharma, Juan Pablo Pena-Rosas

Journal article  |  2019  |  ANNALS OF THE NEW YORK ACADEMY OF SCIENCES

Anemia is an important public health problem that negatively affects health of individuals and economic potential of populations. ..

Rapid growth is a dominant predictor of hepcidin suppression and declining ferritin in Gambian infants

Andrew E Armitage, Schadrac C Agbla, Modupeh Betts, Ebrima A Sise, Momodou W Jallow, Ellen Sambou, Bakary Darboe, Archibald Worwui, George M Weinstock, Martin Antonio, Sant-Rayn Pasricha, Andrew M Prentice, Hal Drakesmith, Momodou K Darboe, Brenda Anna Kwambana-Adams

Journal article  |  2019  |  HAEMATOLOGICA

Iron deficiency and iron deficiency anemia are highly prevalent in low-income countries, especially among young children. Hepcidin..