Catarina Dos Santos Sa E Almeida

Glycolipid-peptide vaccination induces liver-resident memory CD8( ) T cells that protect against rodent malaria

Lauren E Holz, Yu Cheng Chua, Maria N de Menezes, Regan J Anderson, Sarah L Draper, Benjamin J Compton, Susanna TS Chan, Juby Mathew, Jasmine Li, Lukasz Kedzierski, Zhongfang Wang, Lynette Beattie, Matthias H Enders, Sonia Ghilas, Rose May, Thiago M Steiner, Joshua Lange, Daniel Fernandez-Ruiz, Ana Maria Valencia-Hernandez, Taryn L Osmond, et al.

Journal article  |  2020  |  Science Immunology

Liver resident-memory CD8+ T cells (TRM cells) can kill liver-stage Plasmodium-infected cells and prevent malaria, but simple vacc..

alpha-Glucuronosyl and alpha-glucosyl diacylglycerides, natural killer T cell-activating lipids from bacteria and fungi

Satvika Burugupalli, Catarina F Almeida, Dylan GM Smith, Sayali Shah, Onisha Patel, Jamie Rossjohn, Adam P Uldrich, Dale I Godfrey, Spencer J Williams

Journal article  |  2020  |  Chemical Science

Microbial α-glycosyl diacylglycerides when presented by the antigen presenting molecule CD1d are recognized by both classical type..

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors

Catarina F Almeida, Srinivasan Sundararaj, Jerome Le Nours, T Praveena, Benjamin Cao, Satvika Burugupalli, Dylan GM Smith, Onisha Patel, Manfred Brigl, Daniel G Pellicci, Spencer J Williams, Adam P Uldrich, Dale I Godfrey, Jamie Rossjohn

Journal article  |  2019  |  Nature Communications

Type I and type II natural killer T (NKT) cells are restricted to the lipid antigen-presenting molecule CD1d. While we have an und..

MAIT CELLS CONTRIBUTE TO A PROTECTIVE ANTIVIRAL INNATE RESPONSE TO INFLUENZA INFECTION

TSC Hinks, B van Wilgenburg, L Loh, TJ Pediongco, H Wang, M Shi, Z Zhao, M Koutsakos, S Nussing, S Sant, Z Wang, C D'Souza, CF Almeida, P Reading, AJ Corbett, J McCluskey, P Klenerman, K Kedzierska

Conference Proceedings  |  2018  |  The influence of influenza: from cells to humans

MAIT cells contribute to protection against lethal influenza infection in vivo

Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Xiaoxiao Jia, Catarina F Almeida, Lyudmila Kostenko, Sidonia BG Eckle, Bronwyn S Meehan, Axel Kallies, Dale I Godfrey, Patrick C Reading, et al.

Journal article  |  2018  |  NATURE COMMUNICATIONS

MAIT cells contribute to a protective antiviral innate response to influenza infection

Timothy Hinks, Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nussing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Catarina Almeida, Patrick Reading, Alexandra Corbett, James Mccluskey, Paul Klenerman, Katherine Kedzierska

Conference Proceedings  |  2018  |  Respiratory infections

Augmenting Influenza-Specific T Cell Memory Generation with a Natural Killer T Cell-Dependent Glycolipid-Peptide Vaccine

Regan J Anderson, Jasmine Li, Lukasz Kedzierski, Benjamin J Compton, Colin M Hayman, Taryn L Osmond, Ching-wen Tang, Kathryn J Farrand, Hui-Fern Koay, Catarina Filipa Dos Santos Sa E Almeida, Lauren R Holz, Geoffrey M Williams, Margaret A Brimble, Zhongfang Wang, Marios Koutsakos, Katherine Kedzierska, Dale I Godfrey, Ian F Hermans, Stephen J Turner, Gavin F Painter

Journal article  |  2017  |  ACS Chemical Biology

A three-stage intrathymic development pathway for the mucosal-associated invariant T cell lineage

Hui-Fern Koay, Nicholas A Gherardin, Anselm Enders, Liyen Loh, Laura K Mackay, Catarina F Almeida, Brendan E Russ, Claudia A Nold-Petry, Marcel F Nold, Sammy Bedoui, Zhenjun Chen, Alexandra J Corbett, Sidonia BG Eckle, Bronwyn Meehan, Yves d'Udekem, Igor E Konstantinov, Martha Lappas, Ligong Liu, Chris C Goodnow, David P Fairlie, et al.

Journal article  |  2016  |  NATURE IMMUNOLOGY

Vitamin A restrains gamma delta T cells Taming pathogenic gamma delta T cells with vitamin A

Catarina F Almeida, Dale I Godfrey

Journal article  |  2016  |  Immunology & Cell Biology

Plasticity in CD1d-lipid antigen recognition by non-canonical NKT cells

CF Almeida, S Sundararaj, J Le Nours, O Patel, B Cao, DG Pellicci, S Williams, J Rossjohn, AP Uldrich, DI Godfrey

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

IL-9 Expression by Invariant NKT Cells Is Not Imprinted during Thymic Development.

Marta Monteiro, Ana Agua-Doce, Catarina F Almeida, Diogo Fonseca-Pereira, Henrique Veiga-Fernandes, Luis Graca

Journal article  |  2015  |  The Journal of Immunology

Invariant NKT (iNKT) cell thymic development can lead to distinct committed effector lineages, namely NKT1, NKT2, and NKT17. Howev..

Identification of a Potent Microbial Lipid Antigen for Diverse NKT Cells

Benjamin J Wolf, Raju VV Tatituri, Catarina F Almeida, Jerome Le Nours, Veemal Bhowruth, Darryl Johnson, Adam P Uldrich, Fong-Fu Hsu, Manfred Brigl, Gurdyal S Besra, Jamie Rossjohn, Dale I Godfrey, Michael B Brenner

Journal article  |  2015  |  JOURNAL OF IMMUNOLOGY

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

Raju VV Tatituri, Gerald FM Watts, Veemal Bhowruth, Nathaniel Barton, Alissa Rothchild, Fong-Fu Hsu, Catarina F Almeida, Liam R Cox, Lothar Eggeling, Susanna Cardell, Jamie Rossjohn, Dale I Godfrey, Samuel M Behar, Gurdyal S Besra, Michael B Brenner, Manfred Brigl

Journal article  |  2013  |  PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Induced IL-17-producing invariant NKT cells require activation in presence of TGF-β and IL-1β.

Marta Monteiro, Catarina F Almeida, Ana Agua-Doce, Luis Graca

Journal article  |  2013  |  The Journal of Immunology

IL-17 production by innate-like lymphocytes, including γδ and invariant NKT (iNKT) cells, have been ascribed to specific lineages ..

T cell apoptosis and induction of Foxp3 regulatory T cells underlie the therapeutic efficacy of CD4 blockade in experimental autoimmune encephalomyelitis.

Joana Duarte, Nadège Carrié, Vanessa G Oliveira, Catarina Almeida, Ana Agua-Doce, Lénia Rodrigues, J Pedro Simas, Lennart T Mars, Luis Graca

Journal article  |  2012  |  The Journal of Immunology

The pathogenesis of multiple sclerosis requires the participation of effector neuroantigen-specific T cells. Thus, T cell targetin..

Regulation of the germinal center reaction by Foxp3 follicular regulatory T cells.

Ivonne Wollenberg, Ana Agua-Doce, Andrea Hernández, Catarina Almeida, Vanessa G Oliveira, Jose Faro, Luis Graca

Journal article  |  2011  |  The Journal of Immunology

Follicular helper T (T(FH)) cells participate in humoral responses providing selection signals to germinal center B cells. Recentl..

Identification of regulatory Foxp3 invariant NKT cells induced by TGF-beta.

Marta Monteiro, Catarina F Almeida, Marta Caridade, Julie C Ribot, Joana Duarte, Ana Agua-Doce, Ivonne Wollenberg, Bruno Silva-Santos, Luis Graca

Journal article  |  2010  |  The Journal of Immunology

Invariant NKT (iNKT) cells were shown to prevent the onset of experimental autoimmune encephalomyelitis in mice following administ..