Sarah-Jane Dawson

Detection of cell-free microbial DNA using a contaminant-controlled analysis framework

Enrique Zozaya-Valdes, Stephen Q Wong, Jeanette Raleigh, Athena Hatzimihalis, Sarah Ftouni, Anthony T Papenfuss, Shahneen Sandhu, Mark A Dawson, Sarah-Jane Dawson

Journal article  |  2021  |  GENOME BIOLOGY

BACKGROUND: The human microbiome plays an important role in cancer. Accumulating evidence indicates that commensal microbiome-deri..

HIV is associated with an increased risk of age-related clonal hematopoiesis among older adults

Nila J Dharan, Paul Yeh, Mark Bloch, Miriam M Yeung, David Baker, Jerick Guinto, Norman Roth, Sarah Ftouni, Katherine Ognenovska, Don Smith, Jennifer F Hoy, Ian Woolley, Catherine Pell, David J Templeton, Neil Fraser, Nectarios Rose, Jolie Hutchinson, Kathy Petoumenos, Sarah-Jane Dawson, Mark N Polizzotto, et al.

Journal article  |  2021  |  NATURE MEDICINE

People with human immunodeficiency virus (HIV) have higher rates of certain comorbidities, particularly cardiovascular disease and..

Evolution of late-stage metastatic melanoma is dominated by aneuploidy and whole genome doubling

Ismael A Vergara, Christopher P Mintoff, Shahneen Sandhu, Lachlan McIntosh, Richard J Young, Stephen Q Wong, Andrew Colebatch, Daniel L Cameron, Julia Lai Kwon, Rory Wolfe, Angela Peng, Jason Ellul, Xuelin Dou, Clare Fedele, Samantha Boyle, Gisela Mir Arnau, Jeanette Raleigh, Athena Hatzimihalis, Pacman Szeto, Jennifer Mooi, et al.

Journal article  |  2021  |  NATURE COMMUNICATIONS

Although melanoma is initiated by acquisition of point mutations and limited focal copy number alterations in melanocytes-of-origi..

P76.64 Alternating Osimertinib and Gefitinib as Second-Line Treatment for EGFR-Mutated NSCLC Harbouring a T790M Resistance Mutation (OSCILLATE)

B Solomon, A Mersiades, C Brown, S Dawson, S Wong, L Tan, S Yip, Y Cheung, H Jurkovic, M Walker, S Kao, CK Lee, G Newnham, K O'Byrne, S Parakh, K Jasas, V Bray, M Stockler, T John, N Pavlakis

Journal article  |  2021  |  Journal of Thoracic Oncology

Alternating Osimertinib and Gefitinib as Second-Line Treatment for EGFR-Mutated NSCLC Harbouring a T790M Resistance Mutation (OSCILLATE)

B Solomon, A Mersiades, C Brown, S Dawson, S Wong, L Tan, S Yip, Y Cheung, H Jurkovic, M Walker, S Kao, CK Lee, G Newnham, K O'Byrne, S Parakh, K Jasas, V Bray, M Stockler, T John, N Pavlakis

Conference Proceedings  |  2021  |  JOURNAL OF THORACIC ONCOLOGY

Abstract OT-27-01: PALVEN: A phase 1b study of palbociclib, letrozole and venetoclax in estrogen receptor, BCL2-positive metastatic breast cancer

Christine Muttiah, Avraham Travers, James R Whittle, Sarah-Jane Dawson, Belinda Yeo, Jane E Visvader, Catherine Oakman, Geoffrey J Lindeman

Conference Proceedings  |  2021  |  Ongoing Clinical Trials Abstracts

PALVEN: A phase 1b study of palbociclib, letrozole and venetoclax in estrogen receptor, BCL2-positive metastatic breast cancer

Christine Muttiah, Avraham Travers, James R Whittle, Sarah-Jane Dawson, Belinda Yeo, Jane E Visvader, Catherine Oakman, Geoffrey J Lindeman

Conference Proceedings  |  2021  |  CANCER RESEARCH

Towards Routine Implementation of Liquid Biopsies in Cancer Management: It Is Always Too Early, until Suddenly It Is Too Late

Maarten J IJzerman, Jasper de Boer, Arun Azad, Koen Degeling, Joel Geoghegan, Chelsee Hewitt, Frederic Hollande, Belinda Lee, Yat Ho To, Richard W Tothill, Gavin Wright, Jeanne Tie, Sarah-Jane Dawson

Journal article  |  2021  |  DIAGNOSTICS

Blood-based liquid biopsies are considered a new and promising diagnostic and monitoring tool for cancer. As liquid biopsies only ..

Circulating Tumor DNA Predicts Outcome from First-, but not Second-line Treatment and Identifies Melanoma Patients Who May Benefit from Combination Immunotherapy

Gabriela Marsavela, Jenny Lee, Leslie Calapre, Stephen Q Wong, Michelle R Pereira, Ashleigh C McEvoy, Anna L Reid, Cleo Robinson, Lydia Warburton, Afaf Abed, Muhammad A Khattak, Tarek M Meniawy, Sarah-Jane Dawson, Shahneen Sandhu, Matteo S Carlino, Alexander M Menzies, Richard A Scolyer, Georgina Long, Benhur Amanuel, Michael Millward, et al.

Journal article  |  2020  |  CLINICAL CANCER RESEARCH

PURPOSE: We evaluated the predictive value of pretreatment ctDNA to inform therapeutic outcomes in patients with metastatic melano..

Longitudinal Genomic Characterization Using Cell-Free DNA in Patients with Idiopathic Aplastic Anemia

Georgina L Ryland, Lucy C Fox, Xiangting Chen, Satwica Yerneni, Jeffrey Szer, Ashish Bajel, Robin J Filshie, Sue Morgan, Sarah-Jane Dawson, Piers Blombery

Journal article  |  2020  |  Blood

The molecular profile of clonal hematopoiesis in patients (pts) with idiopathic aplastic anaemia (iAA) has been shown to predict r..