Bernhard Baune

Monocyte mitochondrial dysfunction, inflammaging, and inflammatory pyroptosis in major depression.

Maria S Simon, Carmen Schiweck, Gara Arteaga-Henríquez, Sara Poletti, Bartholomeus CM Haarman, Wim A Dik, Markus Schwarz, Elske Vrieze, Olya Mikova, Silke Joergens, Richard Musil, Stephan Claes, Bernhard T Baune, Marion Leboyer, Francesco Benedetti, Roberto Furlan, Raf Berghmans, Harm de Wit, Annemarie Wijkhuijs, Volker Arolt, et al.

Journal article  |  2021  |  Prog Neuropsychopharmacol Biol Psychiatry

BACKGROUND: The macrophage theory of depression states that macrophages play an important role in Major Depressive Disorder (MDD)...

HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders

Sigrid Le Clerc, Laura Lombardi, Bernhard T Baune, Azmeraw T Amare, Klaus Oliver Schubert, Liping Hou, Scott R Clark, Sergi Papiol, Micah Cearns, Urs Heilbronner, Franziska Degenhardt, Fasil Tekola-Ayele, Yi-Hsiang Hsu, Tatyana Shekhtman, Mazda Adli, Nirmala Akula, Kazufumi Akiyama, Rafaella Ardau, Barbara Arias, Jean-Michel Aubry, et al.

Journal article  |  2021  |  SCIENTIFIC REPORTS

Bipolar affective disorder (BD) is a severe psychiatric illness, for which lithium (Li) is the gold standard for acute and mainten..

Acute effect of vagus nerve stimulation (VNS) on brain function

Erhan Kavakbasi, Joachim Gross, Andreas Wollbrink, Ruth Fellmeth, Bernhard T Baune

Journal article  |  2021  |  JOURNAL OF PSYCHIATRIC RESEARCH

INTRODUCTION: VNS is a non-pharmalogical neuromodulatory treatment option for difficult-to-treat depression. A pulse generator imp..

Molecular biomarkers of electroconvulsive therapy effects and clinical response: Understanding the present to shape the future

E Maffioletti, RC Silva, M Bortolomasi, BT Baune, M Gennarelli, A Minelli

Journal article  |  2021  |  Brain Sciences

Electroconvulsive therapy (ECT) represents an effective intervention for treatment-resistant depression (TRD). One priority of thi..

Variations in seasonal solar insolation are associated with a history of suicide attempts in bipolar I disorder

Michael Bauer, Tasha Glenn, Eric D Achtyes, Martin Alda, Esen Agaoglu, Kursat Altinbas, Ole A Andreassen, Elias Angelopoulos, Raffaella Ardau, Edgar Arrua Vares, Memduha Aydin, Yavuz Ayhan, Christopher Baethge, Rita Bauer, Bernhard T Baune, Ceylan Balaban, Claudia Becerra-Palars, Aniruddh P Behere, Prakash B Behere, Habte Belete, et al.

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF BIPOLAR DISORDERS

BACKGROUND: Bipolar disorder is associated with circadian disruption and a high risk of suicidal behavior. In a previous explorato..

Brain microstructural changes in mice persist in adulthood and are modulated by the palmitoyl acyltransferase ZDHHC7

Nicole Kerkenberg, Lydia Wachsmuth, Mingyue Zhang, Christiane Schettler, Evgeni Ponimaskin, Cornelius Faber, Bernhard T Baune, Weiqi Zhang, Christa Hohoff

Journal article  |  2021  |  EUROPEAN JOURNAL OF NEUROSCIENCE

For a long time, mice have been classified as adults with completely mature brains at 8 weeks of age, but recent research suggests..

Brain Correlates of Suicide Attempt in 18,925 Participants Across 18 International Cohorts

Adrian Campos, Paul M Thompson, Dick J Veltman, Elena Pozzi, Laura S van Veltzen, Neda Jahanshad, Mark J Adams, Bernhard T Baune, Klaus Berger, Katharina Brosch, Robin Bulow, Colm G Connolly, Udo Dannlowski, Christopher G Davey, Greig de Zubicaray, Danai Dima, Tracy Erwin-Grabner, Jennifer W Evans, Cynthia HY Fu, Ian H Gotlib, et al.

Journal article  |  2021  |  BIOLOGICAL PSYCHIATRY

BACKGROUND: Neuroimaging studies of suicidal behavior have so far been conducted in small samples, prone to biases and false-posit..

Use of multidimensional item response theory methods for dementia prevalence prediction: an example using the Health and Retirement Survey and the Aging, Demographics, and Memory Study

Emma Nichols, Foad Abd-Allah, Amir Abdoli, Ahmed Abualhasan, Eman Abu-Gharbieh, Ashkan Afshin, Rufus Olusola Akinyemi, Fahad Mashhour Alanezi, Vahid Alipour, Amir Almasi-Hashiani, Jalal Arabloo, Amir Ashraf-Ganjouei, Getinet Ayano, Jose L Ayuso-Mateos, Atif Amin Baig, Maciej Banach, Miguel A Barboza, Suzanne Lyn Barker-Collo, Bernhard T Baune, Akshaya Srikanth Bhagavathula, et al.

Journal article  |  2021  |  BMC MEDICAL INFORMATICS AND DECISION MAKING

BACKGROUND: Data sparsity is a major limitation to estimating national and global dementia burden. Surveys with full diagnostic ev..

No evidence for clinical efficacy of adjunctive celecoxib with vortioxetine in the treatment of depression: A 6-week double-blind placebo controlled randomized trial.

Bernhard T Baune, Emma Sampson, Jennie Louise, Hikaru Hori, K Oliver Schubert, Scott R Clark, Natalie T Mills, Célia Fourrier

Journal article  |  2021  |  Eur Neuropsychopharmacol

Given the role of low-grade inflammation in the pathophysiology of major depressive disorder (MDD), anti-inflammatory strategies m..

Cerebrospinal fluid flow cytometry distinguishes psychosis spectrum disorders from differential diagnoses.

Saskia Räuber, Michael Heming, Jonathan Repple, Tillmann Ruland, Rebecca Kuelby, Andreas Schulte-Mecklenbeck, Catharina C Gross, Volker Arolt, Bernhard Baune, Tim Hahn, Udo Dannlowski, Sven G Meuth, Nico Melzer, Heinz Wiendl, Gerd Meyer Zu Hörste

Journal article  |  2021  |  Mol Psychiatry

Psychotic disorders are common and disabling mental conditions. The relative importance of immune-related mechanisms in psychotic ..