Pasi Korhonen

Toward integrative 'omics of the barber's pole worm and related parasitic nematodes

Guangxu Ma, Robin B Gasser, Tao Wang, Pasi K Korhonen, Neil D Young

Journal article  |  2020  |  Infection Genetics and Evolution

Advances in nucleic acid sequencing, mass spectrometry and computational biology have facilitated the identification, annotation a..

High-quality nuclear genome for Sarcoptes scabiei-A critical resource for a neglected parasite

Pasi K Korhonen, Robin B Gasser, Guangxu Ma, Tao Wang, Andreas J Stroehlein, Neil D Young, Ching-Seng Ang, Deepani D Fernando, Hieng C Lu, Sara Taylor, Simone L Reynolds, Ehtesham Mofiz, Shivashankar H Najaraj, Harsha Gowda, Anil Madugundu, Santosh Renuse, Deborah Holt, Akhilesh Pandey, Anthony T Papenfuss, Katja Fischer

Journal article  |  2020  |  PLoS Neglected Tropical Diseases

The parasitic mite Sarcoptes scabiei is an economically highly significant parasite of the skin of humans and animals worldwide. I..

First record of a tandem-repeat region within the mitochondrial genome ofClonorchis sinensisusing a long-read sequencing approach

Liina Kinkar, Neil D Young, Woon-Mok Sohn, Andreas J Stroehlein, Pasi K Korhonen, Robin B Gasser

Journal article  |  2020  |  PLoS Neglected Tropical Diseases

BACKGROUND: Mitochondrial genomes provide useful genetic markers for systematic and population genetic studies of parasitic helmin..

Marked mitochondrial genetic variation in individuals and populations of the carcinogenic liver fluke Clonorchis sinensis

Liina Kinkar, Pasi K Korhonen, Daxi Wang, Xing-Quan Zhu, Galina N Chelomina, Tao Wang, Ross S Hall, Anson Koehler, Ivon Harliwong, Bicheng Yang, J Lynn Fink, Neil D Young, Robin B Gasser

Journal article  |  2020  |  PLoS Neglected Tropical Diseases

Clonorchiasis is a neglected tropical disease caused by the Chinese liver fluke, Clonorchis sinensis, and is often associated with..

The developmental phosphoproteome of Haemonchus contortus

Tao Wang, Guangxu Ma, Ching-Seng Ang, Pasi K Korhonen, Andreas J Stroehlein, Neil D Young, Andreas Hofmann, Bill CH Chang, Nicholas A Williamson, Robin B Gasser

Journal article  |  2020  |  Journal of Proteomics

Protein phosphorylation plays essential roles in many cellular processes. Despite recent progress in the genomics, transcriptomics..

Gene content evolution in the arthropods

Gregg WC Thomas, Elias Dohmen, Daniel ST Hughes, Shwetha C Murali, Monica Poelchau, Karl Glastad, Clare A Anstead, Nadia A Ayoub, Phillip Batterham, Michelle Bellair, Greta J Binford, Hsu Chao, Yolanda H Chen, Christopher Childers, Huyen Dinh, Harsha Vardhan Doddapaneni, Jian J Duan, Shannon Dugan, Lauren A Esposito, Markus Friedrich, et al.

Journal article  |  2020  |  GENOME BIOLOGY

BACKGROUND: Arthropods comprise the largest and most diverse phylum on Earth and play vital roles in nearly every ecosystem. Their..

Elucidating the molecular and developmental biology of parasitic nematodes: Moving to a multiomics paradigm.

Guangxu Ma, Tao Wang, Pasi K Korhonen, Andreas Hofmann, Paul W Sternberg, Neil D Young, Robin B Gasser

Book Chapter  |  2020  |  Advances in Parasitology

In the past two decades, significant progress has been made in the sequencing, assembly, annotation and analyses of genomes and tr..

Predicting gene essentiality in Caenorhabditis elegans by feature engineering and machine-learning.

Tulio L Campos, Pasi K Korhonen, Paul W Sternberg, Robin B Gasser, Neil D Young

Journal article  |  2020  |  Computational and Structural Biotechnology Journal

Defining genes that are essential for life has major implications for understanding critical biological processes and mechanisms. ..

High-quality Schistosoma haematobium genome achieved by single-molecule and long-range sequencing

Andreas J Stroehlein, Pasi K Korhonen, Teik Min Chong, Yan Lue Lim, Kok Gan Chan, Bonnie Webster, David Rollinson, Paul J Brindley, Robin B Gasser, Neil D Young

Journal article  |  2019  |  GigaScience

BACKGROUND: Schistosoma haematobium causes urogenital schistosomiasis, a neglected tropical disease affecting >100 million people ..

High throughput LC-MS/MS-based proteomic analysis of excretory-secretory products from short-term in vitro culture of Haemonchus contortus

Tao Wang, Guangxu Ma, Ching-Seng Ang, Pasi K Korhonen, Anson Koehler, Neil D Young, Shuai Nie, Nicholas A Williamson, Robin B Gasser

Journal article  |  2019  |  Journal of Proteomics

Parasitic nematodes of humans, animals and plants have a major, adverse impact on global health and agricultural production worldw..