Pasi Korhonen

High-Throughput Phenotypic Assay to Screen for Anthelmintic Activity on Haemonchus contortus

Aya C Taki, Joseph J Byrne, Tao Wang, Brad E Sleebs, Nghi Nguyen, Ross S Hall, Pasi K Korhonen, Bill CH Chang, Paul Jackson, Abdul Jabbar, Robin B Gasser

Journal article  |  2021  |  PHARMACEUTICALS

Parasitic worms cause very significant diseases in animals and humans worldwide, and their control is critical to enhance health, ..

High-quality reference genome for Clonorchis sinensis

Neil D Young, Andreas J Stroehlein, Liina Kinkar, Tao Wang, Woon-Mok Sohn, Bill CH Chang, Parwinder Kaur, David Weisz, Olga Dudchenko, Erez Lieberman Aiden, Pasi K Korhonen, Robin B Gasser

Journal article  |  2021  |  GENOMICS

The Chinese liver fluke, Clonorchis sinensis, causes the disease clonorchiasis, affecting ~35 million people in regions of China, ..

Cross-Predicting Essential Genes between Two Model Eukaryotic Species Using Machine Learning

Tulio L Campos, Pasi K Korhonen, Neil D Young

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Experimental studies of Caenorhabditis elegans and Drosophila melanogaster have contributed substantially to our understanding of ..

Dipylidium caninum draft genome-a new resource for comparative genomic and genetic explorations of flatworms

Guo-Hua Liu, Pasi K Korhonen, Neil D Young, Jiang Lu, Tao Wang, Yi-Tian Fu, Anson V Koehler, Andreas Hofmann, Bill CH Chang, Shuai Wang, Nan Li, Chu-Yu Lin, Hui Zhang, Lingzi Xiangli, Lin Lin, Wei-Min Liu, Nan Li, Hua-Wei Li, Robin B Gasser, Xing-Quan Zhu

Journal article  |  2021  |  GENOMICS

Here, we present a draft genome of the tapeworm Dipylidium caninum (family Dipylidiidae) and compare it with other cestode genomes..

Nanopore Sequencing Resolves Elusive Long Tandem-Repeat Regions in Mitochondrial Genomes

Liina Kinkar, Robin B Gasser, Bonnie L Webster, David Rollinson, D Timothy J Littlewood, Bill CH Chang, Andreas J Stroehlein, Pasi K Korhonen, Neil D Young

Journal article  |  2021  |  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Long non-coding, tandem-repetitive regions in mitochondrial (mt) genomes of many metazoans have been notoriously difficult to char..

Molecular diagnosis of scabies using a novel probe-based polymerase chain reaction assay targeting high-copy number repetitive sequences in the Sarcoptes scabiei genome

Lena Chng, Deborah C Holt, Matt Field, Joshua R Francis, Dev Tilakaratne, Milou H Dekkers, Greg Robinson, Kate Mounsey, Rebecca Pavlos, Asha C Bowen, Katja Fischer, Anthony T Papenfuss, Robin B Gasser, Pasi K Korhonen, Bart J Currie, James S McCarthy, Cielo Pasay

Journal article  |  2021  |  PLOS NEGLECTED TROPICAL DISEASES

BACKGROUND: The suboptimal sensitivity and specificity of available diagnostic methods for scabies hampers clinical management, tr..

OGEE v3: Online GEne Essentiality database with increased coverage of organisms and human cell lines

Sanathoi Gurumayum, Puzi Jiang, Xiaowen Hao, Tulio L Campos, Neil D Young, Pasi K Korhonen, Robin B Gasser, Peer Bork, Xing-Ming Zhao, Li-jie He, Wei-Hua Chen

Journal article  |  2021  |  NUCLEIC ACIDS RESEARCH

OGEE is an Online GEne Essentiality database. Gene essentiality is not a static and binary property, rather a context-dependent an..

Bulinus truncatus transcriptome – a resource to enable molecular studies of snail and schistosome biology

Andreas J Stroehlein, Pasi K Korhonen, David Rollinson, J Russell Stothard, Ross S Hall, Robin B Gasser, Neil D Young

Journal article  |  2021  |  Current Research in Parasitology & Vector-Borne Diseases

Mitochondrial genome of Bulinus truncatus (Gastropoda: Lymnaeoidea): Implications for snail systematics and schistosome epidemiology

Neil D Young, Liina Kinkar, Andreas J Stroehlein, Pasi K Korhonen, J Russell Stothard, David Rollinson, Robin B Gasser

Journal article  |  2021  |  Current Research in Parasitology & Vector-Borne Diseases

Toward integrative 'omics of the barber's pole worm and related parasitic nematodes

Guangxu Ma, Robin B Gasser, Tao Wang, Pasi K Korhonen, Neil D Young

Journal article  |  2020  |  INFECTION GENETICS AND EVOLUTION

Advances in nucleic acid sequencing, mass spectrometry and computational biology have facilitated the identification, annotation a..