Lisa Mielke

TCF-1 limits the formation of Tc17 cells via repression of the MAF-ROR gamma t axis

Lisa A Mielke, Yang Liao, Ella Bridie Clemens, Matthew A Firth, Brigette Duckworth, Qiutong Huang, Francisca F Almeida, Michael Chopin, Hui-Fern Koay, Carolyn A Bell, Soroor Hediyeh-Zadeh, Simone L Park, Dinesh Raghu, Jarny Choi, Tracy L Putoczki, Philip D Hodgkin, Ashley E Franks, Laura K Mackay, Dale Godfrey, Melissa J Davis, et al.

Journal article  |  2019  |  Journal of Experimental Medicine

Transcription Factor PU.1 Promotes Conventional Dendritic Cell Identity and Function via Induction of Transcriptional Regulator DC-SCRIPT

Michael Chopin, Aaron T Lun, Yifan Zhan, Jaring Schreuder, Hannah Coughlan, Angela D'Amico, Lisa A Mielke, Francisca F Almeida, Andrew J Kueh, Ross A Dickins, Gabrielle T Belz, Shalin H Naik, Andrew M Lew, Phillipe Bouillet, Marco J Herold, Gordon K Smyth, Lynn M Corcoran, Stephen L Nutt

Journal article  |  2019  |  Immunity

Plasmacytoid dendritic cell heterogeneity is defined by CXCL10 expression following TLR7 stimulation

Casper Marsman, Fanny Lafouresse, Yang Liao, Tracey M Baldwin, Lisa A Mielke, Yifang Hu, Matthias Mack, Paul J Hertzog, Carolyn A de Graaf, Wei Shi, Joanna R Groom

Journal article  |  2018  |  Immunology and Cell Biology

NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease

Hazel Tye, Chien-Hsiung Yu, Lisa A Simms, Marcel R de Zoete, Man Lyang Kim, Martha Zakrzewski, Jocelyn S Penington, Cassandra R Harapas, Fernando Souza-Fonseca-Guimaraes, Leesa F Wockner, Adele Preaudet, Lisa A Mielke, Stephen A Wilcox, Yasunori Ogura, Sinead C Corr, Komal Kanojia, Konstantinos A Kouremenos, David P De Souza, Malcolm J McConville, Richard A Flavell, et al.

Journal article  |  2018  |  Nature Communications

Characterization of Blimp-1 function in effector regulatory T cells

Erika Cretney, Patrick SK Leung, Stephanie Trezise, Dane M Newman, Lucille C Rankin, Charis E Teh, Tracy L Putoczki, Daniel HD Gray, Gabrielle T Belz, Lisa A Mielke, Sheila Dias, Stephen L Nutt

Journal article  |  2018  |  Journal of Autoimmunity

Loss of NF-kappa B1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner

Lorraine A O'Reilly, Tracy L Putoczki, Lisa A Mielke, Jun T Low, Ann Lin, Adele Preaudet, Marco J Herold, Kelvin Yaprianto, Lin Tai, Andrew Kueh, Guido Pacini, Richard L Ferrero, Raffi Gugasyan, Yifang Hu, Michael Christie, Stephen Wilcox, Raelene Grumont, Michael DW Griffin, Liam O'Connor, Gordon K Smyth, et al.

Journal article  |  2018  |  Immunity

The TNF Receptor Superfamily-NF-kappa B Axis Is Critical to Maintain Effector Regulatory T Cells in Lymphoid and Non-lymphoid Tissues

Ajithkumar Vasanthakumar, Yang Liao, Peggy Teh, Maria F Pascutti, Anna E Oja, Alexandra L Garnham, Renee Gloury, Jessica C Tempany, Tom Sidwell, Eloy Cuadrado, Paul Tuijnenburg, Taco W Kuijpers, Najoua Lalaoui, Lisa A Mielke, Vanessa L Bryant, Philip D Hodgkin, John Silke, Gordon K Smyth, Martijn A Nolte, Wei Shi, et al.

Journal article  |  2017  |  Cell Reports

Deciphering the Innate Lymphoid Cell Transcriptional Program

Cyril Seillet, Lisa A Mielke, Daniela B Amann-Zalcenstein, Shian Su, Jerry Gao, Francisca F Almeida, Wei Shi, Matthew E Ritchie, Shalin H Naik, Nicholas D Huntington, Sebastian Carotta, Gabrielle T Belz

Journal article  |  2016  |  Cell Reports

NF kappa B1 suppresses intestinal-type gastric cancer development by preventing chronic inflammation in the stomach

LA O'Reilly, TP Putoczki, L Mielke, A Lin, A Preaudet, JT Low, MJ Herold, L Tai, R Ferrero, Y Hu, R Grumont, G Smyth, M Ernst, P Waring, S Gerondakis, A Strasser

Conference Proceedings  |  2016  |  EUROPEAN JOURNAL OF IMMUNOLOGY

Granzyme M has a critical role in providing innate immune protection in ulcerative colitis

F Souza-Fonseca-Guimaraes, Y Krasnova, T Putoczki, K Miles, KP MacDonald, L Town, W Shi, GC Gobe, L McDade, LA Mielke, H Tye, SL Masters, GT Belz, ND Huntington, G Radford-Smith, MJ Smyth

Journal article  |  2016  |  Cell Death & Disease

Complementarity and redundancy of IL-22-producing innate lymphoid cells

Lucille C Rankin, Mathilde JH Girard-Madoux, Cyril Seillet, Lisa A Mielke, Yann Kerdiles, Aurore Fenis, Elisabeth Wieduwild, Tracy Putoczki, Stanislas Mondot, Olivier Lantz, Dieter Demon, Anthony T Papenfuss, Gordon K Smyth, Mohamed Lamkanfi, Sebastian Carotta, Jean-Christophe Renauld, Wei Shi, Sabrina Carpentier, Tim Soos, Christopher Arendt, et al.

Journal article  |  2016  |  Nature Immunology

The Helix-Loop-Helix Protein ID2 Governs NK Cell Fate by Tuning Their Sensitivity to Interleukin-15

Rebecca B Delconte, Wei Shi, Priyanka Sathe, Takashi Ushiki, Cyril Seillet, Martina Minnich, Tatiana B Kolesnik, Lucille C Rankin, Lisa A Mielke, Jian-Guo Zhang, Meinrad Busslinger, Mark J Smyth, Dana S Hutchinson, Stephen L Nutt, Sandra E Nicholson, Warren S Alexander, Lynn M Corcoran, Eric Vivier, Gabrielle T Belz, Sebastian Carotta, et al.

Journal article  |  2016  |  Immunity

T-box Transcription Factors Combine with the Cytokines TGF-beta and IL-15 to Control Tissue-Resident Memory T Cell Fate

Laura K Mackay, Erica Wynne-Jones, David Freestone, Daniel G Pellicci, Lisa A Mielke, Dane M Newman, Asolina Braun, Frederick Masson, Axel Kallies, Gabrielle T Belz, Francis R Carbone

Journal article  |  2015  |  Immunity

Confocal laser endomicroscopy to monitor the colonic mucosa of mice

Lisa Mielke, Adele Preaudet, Gabrielle Belz, Tracy Putoczki

Journal article  |  2015  |  Journal of Immunological Methods

The transcriptional regulators IRF4, BATF and IL-33 orchestrate development and maintenance of adipose tissue-resident regulatory T cells

Ajithkumar Vasanthakumar, Kazuyo Moro, Annie Xin, Yang Liao, Renee Gloury, Shimpei Kawamoto, Sidonia Fagarasan, Lisa A Mielke, Shoukat Afshar-Sterle, Seth L Masters, Susumu Nakae, Hirohisa Saito, John M Wentworth, Peng Li, Wei Liao, Warren J Leonard, Gordon K Smyth, Wei Shi, Stephen L Nutt, Shigeo Koyasu, et al.

Journal article  |  2015  |  Nature Immunology

Complexity of cytokine network regulation of innate lymphoid cells in protective immunity

Cyril Seillet, Gabrielle T Belz, Lisa A Mielke

Journal article  |  2014  |  Cytokine

Nfil3 is required for the development of all innate lymphoid cell subsets

Cyril Seillet, Lucille C Rankin, Joanna R Groom, Lisa A Mielke, Julie Tellier, Michael Chopin, Nicholas D Huntington, Gabrielle T Belz, Sebastian Carotta

Journal article  |  2014  |  Journal of Experimental Medicine

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells

Priyanka Sathe, Rebecca B Delconte, Fernando Souza-Fonseca-Guimaraes, Cyril Seillet, Michael Chopin, Cassandra J Vandenberg, Lucille C Rankin, Lisa A Mielke, Ingela Vikstrom, Tatiana B Kolesnik, Sandra E Nicholson, Eric Vivier, Mark J Smyth, Stephen L Nutt, Stefan P Glaser, Andreas Strasser, Gabrielle T Belz, Sebastian Carotta, Nicholas D Huntington

Journal article  |  2014  |  Nature Communications

TCF-1 Controls ILC2 and NKp46( )ROR gamma t( ) Innate Lymphocyte Differentiation and Protection in Intestinal Inflammation

Lisa A Mielke, Joanna R Groom, Lucille C Rankin, Cyril Seillet, Frederick Masson, Tracy Putoczki, Gabrielle T Belz

Journal article  |  2013  |  Journal of Immunology

The transcription factor T-bet is essential for the development of NKp46( ) innate lymphocytes via the Notch pathway

Lucille C Rankin, Joanna R Groom, Michael Chopin, Marco J Herold, Jennifer A Walker, Lisa A Mielke, Andrew NJ McKenzie, Sebastian Carotta, Stephen L Nutt, Gabrielle T Belz

Journal article  |  2013  |  Nature Immunology

Diversity, function, and transcriptional regulation of gut innate lymphocytes

Lucille Rankin, Joanna Groom, Lisa A Mielke, Cyril Seillet, Gabrielle T Belz

Journal article  |  2013  |  Frontiers in Immunology

A mutation in the translation initiation codon of Gata-1 disrupts megakaryocyte maturation and causes thrombocytopenia

Ian J Majewski, Donald Metcalf, Lisa A Mielke, Danielle L Krebs, Sarah Ellis, Marina R Carpinelli, Sandra Mifsud, Ladina Di Rago, Jason Corbin, Nicos A Nicola, Douglas J Hilton, Warren S Alexander

Journal article  |  2006  |  Proceedings of the National Academy of Sciences of the United States of America