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Displaying the 3 most recent scholarly works by Maximilien Tailler.
TBK1 and IKK epsilon Act Redundantly to Mediate STING-Induced NF-kappa B Responses in Myeloid Cells
Katherine R Balka, Cynthia Louis, Tahnee L Saunders, Amber M Smith, Dale J Calleja, Damian B D'Silva, Fiona Moghaddas, Maximilien Tailler, Kate E Lawlor, Yifan Zhan, Christopher J Burns, Ian P Wicks, Jonathan J Miner, Benjamin T Kile, Seth L Masters, Dominic De Nardo
Journal article | 2020 | Cell Reports
Stimulator of Interferon Genes (STING) is a critical component of host innate immune defense but can contribute to chronic autoimm..
By reducing global mRNA translation in several ways, 2-deoxyglucose lowers MCL-1 protein and sensitizes hemopoietic tumor cells to BH3 mimetic ABT737
Maximilien Tailler, Lisa M Lindqvist, Leonie Gibson, Jerry M Adams
Journal article | 2019 | Cell Death and Differentiation
Drugs targeting various pro-survival BCL-2 family members (''BH3 mimetics'') have efficacy in hemopoietic malignancies, but the no..
Medical Biology (W.E.H.I.)