Con Sonza

Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics

Sri H Ramarathinam, Stephanie Gras, Sheilajen Alcantara, Amanda WS Yeung, Nicole A Mifsud, Secondo Sonza, Patricia T Illing, Elias N Glaros, Robert J Center, Shane R Thomas, Stephen J Kent, Nicola Ternette, Damian FJ Purcell, Jamie Rossjohn, Anthony W Purcell

Journal article  |  2018  |  PROTEOMICS

Increasing prevalence of K65K and K66K in HIV-1 subtype B reverse transcriptase

Sushama Telwatte, Chanson J Brumme, Anna C Hearps, Catherine F Latham, Joshua A Hayward, Secondo Sonza, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian

Journal article  |  2016  |  AIDS

MYB Elongation Is Regulated by the Nucleic Acid Binding of NF kappa B p50 to the Intronic Stem-Loop Region

Lloyd A Pereira, Honor J Hugo, Jordane Malaterre, Huiling Xu, Secondo Sonza, Alina Cures, Damian FJ Purcell, Paul A Ramsland, Steven Gerondakis, Thomas J Gonda, Robert G Ramsay

Journal article  |  2015  |  PLOS ONE

Silent mutations at codons 65 and 66 in reverse transcriptase alleviate indel formation and restore fitness in subtype B HIV-1 containing D67N and K70R drug resistance mutations

Sushama Telwatte, Anna C Hearps, Adam Johnson, Catherine F Latham, Katie Moore, Paul Agius, Mary Tachedjian, Secondo Sonza, Nicolas Sluis-Cremer, P Richard Harrigan, Gilda Tachedjian

Journal article  |  2015  |  Nucleic Acids Research

Vaginal concentrations of lactic acid potently inactivate HIV

Muriel Aldunate, David Tyssen, Adam Johnson, Tasnim Zakir, Secondo Sonza, Thomas Moench, Richard Cone, Gilda Tachedjian

Journal article  |  2013  |  Journal of Antimicrobial Chemotherapy

Phosphatidylethanolamine Binding Is a Conserved Feature of Cyclotide-Membrane Interactions

Sonia Troeira Henriques, Yen-Hua Huang, Miguel ARB Castanho, Luis A Bagatolli, Secondo Sonza, Gilda Tachedjian, Norelle L Daly, David J Craik

Journal article  |  2012  |  Journal of Biological Chemistry

SPL7013 Gel (VivaGel (R)) Retains Potent HIV-1 and HSV-2 Inhibitory Activity following Vaginal Administration in Humans

Clare F Price, David Tyssen, Secondo Sonza, Ashley Davie, Sonya Evans, Gareth R Lewis, Shirley Xia, Tim Spelman, Peter Hodsman, Thomas R Moench, Andrew Humberstone, Jeremy RA Paull, Gilda Tachedjian

Journal article  |  2011  |  PLoS One

Decoding the Membrane Activity of the Cyclotide Kalata B1 THE IMPORTANCE OF PHOSPHATIDYLETHANOLAMINE PHOSPHOLIPIDS AND LIPID ORGANIZATION ON HEMOLYTIC AND ANTI-HIV ACTIVITIES

Sonia Troeira Henriques, Yen-Hua Huang, K Johan Rosengren, Henri G Franquelim, Filomena A Carvalho, Adam Johnson, Secondo Sonza, Gilda Tachedjian, Miguel ARB Castanho, Norelle L Daly, David J Craik

Journal article  |  2011  |  Journal of Biological Chemistry

N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations.

Nicolas Sluis-Cremer, Katie Moore, Jessica Radzio, Secondo Sonza, Gilda Tachedjian

Journal article  |  2010  |  AIDS

We previously demonstrated that N348I in HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance. However, both o..

Enhancement of human immunodeficiency virus type 1 replication is not intrinsic to all polyanion-based microbicides.

Secondo Sonza, Adam Johnson, David Tyssen, Tim Spelman, Gareth R Lewis, Jeremy RA Paull, Gilda Tachedjian

Journal article  |  2009  |  Antimicrobial Agents and Chemotherapy

Polyanion-based microbicides have been developed to prevent the sexual transmission of human immunodeficiency virus (HIV). Recent ..