Terry Mulhern

William Buelow Gould

Terrence Mulhern

Original Creative Work - Textual Work  |  2019

When we arrive at Strahan's Meredith Street boat ramp, our skipper Trevor Dennis already has the eight-metre charter boat on the w..

Making a Drama Out of Biochemistry

Terrence Mulhern

Journal article  |  2019  |  Australian Biochemist

The lights dim, and a hush falls over the audience. An Attenborough-esque naturalist appears on stage and invites us to come in se..

Old Growth, New Conflict

Terrence Mulhern

Original Creative Work - Textual Work  |  2019

The table saw screams as the blade tears through the heart of a two-inch thick piece of Tasmanian oak. I'm resawing this heavy pla..

Understanding the pedagogical practices of biochemistry and molecular biology academics

AA Espinosa, H Verkade, TD Mulhern, JM Lodge

Journal article  |  2019  |  The Australian Educational Researcher

Developing Affective Engagement in Science Education through Performative Pedagogies: The Performing Sciences

Sarah French, Terrence D Mulhern, Rinske Ginsberg

Journal article  |  2019  |  International Journal of Innovation in Science and Mathematics Education

St Valentine's Tears

Terry Mulhern

Book Chapter  |  2019

The competition is for articles up to 3,000 words on any aspect of Tasmanian history prior to the 21st century and entries for thi..

Calder v. Hull

Terrence Mulhern

Original Creative Work - Textual Work  |  2019

On Monday morning, December 12, 1881, James Erskine Calder, the Tasmanian Parliamentary Sergeant-at-Arms, made his way down Murray..

The Performing Sciences

Ruth Aston, Terry Mulhern, Rinske Ginsberg, Sarah French

Conference Proceedings  |  2018

The Roc-COR tandem domain of leucine-rich repeat kinase 2 forms dimers and exhibits conventional Ras-like GTPase properties

Ryan D Mills, Lung-Yu Liang, Daisy Sio-Seng Lio, Yee-Foong Mok, Terrence D Mulhern, George Cao, Michael Griffin, Vijaya B Kenche, Janetta G Culvenor, Heung-Chin Cheng

Journal article  |  2018  |  Journal of Neurochemistry

Four Steps to Solving the Student Misconception Problem

Terrence Mulhern, Heather Verkade

Journal article  |  2018  |  Australian Biochemist

There is no greater frustration than reading a student’s exam answer and realising that they totally and completely got the wrong ..

Saved by the bell

Terrence Mulhern

Journal article  |  2018  |  Australian Biochemist

In June 1963, a young Muhammad Ali – still known at that time as Cassius Clay – had the first of his two bouts against British hea..

Just another manic Monday?

Terrence Mulhern

Journal article  |  2018  |  Australian Biochemist

On Monday 14 May, I once again found myself pretending I was a molecule. For anyone who has seen the cover of the August 2017 issu..

Lutaralipina

Terrence Mulhern

Original Creative Work - Textual Work  |  2018

I'm panting as I struggle over fallen logs and push through prickly scrub. I can just hear the kids' voices, far ahead. I try to h..

Henry Hellyer

Terrence Mulhern

Original Creative Work - Textual Work  |  2018

Thirty kilometres north-west of Wynyard, the Bass Highway sweeps down from the Sisters Hills onto Fords Plain. On the right is the..

Henry Hellyer

Terrence Mulhern

Journal article  |  2018  |  Tasmania 40 Degrees South

Thirty kilometres north-west of Wynyard, the Bass Highway sweeps down from the Sisters Hills onto Fords Plain. On the right is the..

A giant lobster, by any other name

Terrence Mulhern

Scholarly Contribution to Database/Website  |  2018

Correcting misconceptions about the names applied to Tasmania’s giant freshwater crayfish Astacopsis gouldi (Decapoda: Parastacidae)

TD Mulhern

Journal article  |  2018  |  Papers and Proceedings of the Royal Society of Tasmania

Misconceptions as a trigger for enhancing student learning in higher education

H Verkade, TD Mulhern, J Lodge, K Elliott, S Cropper, B Rubinstein, A Horton, C Elliott, A Espinosa, L Dooley, S Frankland, R Mulder, M Livett

Book  |  2017

This handbook presents practical information for university educators looking to confront and correct misconceptions held by their..

Exploring misconceptions as a trigger for enhancing student learning

H Verkade, JM Lodge, K Elliott, TD Mulhern, AA Espinosa, SJ Cropper, BIP Rubinstein

Conference Proceedings  |  2017  |  Research and Development in Higher Education Series

This article addresses the importance of confronting misconceptions in the teaching of the STEM disciplines. First, we review the ..

Why do people with East Asian heritage get flushed after drinking alcohol?

Terrence Mulhern

Scholarly Contribution to Database/Website  |  2017

‘Physical’ Biochemistry, But Not as You’ve Ever Seen it Before…

Terrence Mulhern

Journal article  |  2017  |  Australian Biochemist

Last December, I completed Rinske Ginsberg’s ‘Acting Skills Workshop for Lecturers’ at the Victorian College of the Arts. This wor..

Structural Basis for Receptor Recognition by the Human CD59-Responsive Cholesterol-Dependent Cytolysins

Sara L Lawrence, Michael A Gorman, Susanne C Feil, Terrence D Mulhern, Michael J Kuiper, Adam J Ratner, Rodney K Tweten, Craig J Morton, Michael W Parker

Journal article  |  2016  |  Structure

Crystal structure of Streptococcus pneumoniae pneumolysin provides key insights into early steps of pore formation

Sara L Lawrence, Susanne C Feil, Craig J Morton, Allison J Farrand, Terrence D Mulhern, Michael A Gorman, Kristin R Wade, Rodney K Tweten, Michael W Parker

Journal article  |  2015  |  Scientific Reports

A Biosensor of Src Family Kinase Conformation by Exposable Tetracysteine Useful for Cell-Based Screening

Sevgi Irtegun, Rebecca Wood, Kurt Lackovic, Joerg Schweiggert, Yasmin M Ramdzan, David CS Huang, Terrence D Mulhern, Danny M Hatters

Journal article  |  2014  |  ACS Chemical Biology

Prediction of the Repeat Domain Structures and Impact of Parkinsonism-Associated Variations on Structure and Function of all Functional Domains of Leucine-Rich Repeat Kinase 2 (LRRK2)

Ryan D Mills, Terrence D Mulhern, Fei Liu, Janetta G Culvenor, Heung-Chin Cheng

Journal article  |  2014  |  Human Mutation

The Structure of Integrin alpha 1I Domain in Complex with a Collagen-mimetic Peptide

Yanni K-Y Chin, Stephen J Headey, Biswaranjan Mohanty, Rahul Patil, Paul A McEwan, James D Swarbrick, Terrence D Mulhern, Jonas Emsley, Jamie S Simpson, Martin J Scanlon

Journal article  |  2013  |  Journal of Biological Chemistry

Tyrosine 416 Is Phosphorylated in the Closed, Repressed Conformation of c-Src

Sevgi Irtegun, Rebecca J Wood, Angelique R Ormsby, Terrence D Mulhern, Danny M Hatters

Journal article  |  2013  |  PLoS One

Simultaneous Binding of the Anti-Cancer IgM Monoclonal Antibody PAT-SM6 to Low Density Lipoproteins and GRP78

Zachary Rosenes, Yee-Foong Mok, Shuo Yang, Michael DW Griffin, Terrence D Mulhern, Danny M Hatters, Frank Hensel, Geoffrey J Howlett

Journal article  |  2013  |  PLoS One

Loss of Nucleosomal DNA Condensation Coincides with Appearance of a Novel Nuclear Protein in Dinoflagellates

Sebastian G Gornik, Kristina L Ford, Terrence D Mulhern, Antony Bacic, Geoffrey I McFadden, Ross F Waller

Journal article  |  2012  |  Current Biology

Analysis of LRRK2 accessory repeat domains: prediction of repeat length, number and sites of Parkinson's disease mutations

Ryan D Mills, Terrence D Mulhern, Heung-Chin Cheng, Janetta G Culvenor

Journal article  |  2012  |  Biochemical Society Transactions

The Anti-Cancer IgM Monoclonal Antibody PAT-SM6 Binds with High Avidity to the Unfolded Protein Response Regulator GRP78

Zachary Rosenes, Terrence D Mulhern, Danny M Hatters, Leodevico L Ilag, Barbara E Power, Chris Hosking, Frank Hensel, Geoffrey J Howlett, Yee-Foong Mok

Journal article  |  2012  |  PLoS One

Targeting Lyn tyrosine kinase through protein fusions encompassing motifs of Cbp (Csk-binding protein) and the SOCS box of SOCS1

Rhiannon J Whiting, Christine J Payne, Jiulia Satiaputra, Nicole Kucera, Theresa W Qiu, Sevgi Irtegun, Natalie J Gunn, Neli S Lavova-Azmanova, Terrence D Mulhern, Evan Ingley

Journal article  |  2012  |  Biochemical Journal

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain

Charles A Galea, Mehdi Mobli, Kerrie A McNeil, Terrence D Mulhern, John C Wallace, Glenn F King, Briony E Forbes, Raymond S Norton

Journal article  |  2012  |  Biochimie

Structure of the Lectin Regulatory Domain of the Cholesterol-Dependent Cytolysin Lectinolysin Reveals the Basis for Its Lewis Antigen Specificity

Susanne C Feil, Sara Lawrence, Terrence D Mulhern, Jessica K Holien, Eileen M Hotze, Stephen Farrand, Rodney K Tweten, Michael W Parker

Journal article  |  2012  |  Structure

Insulin-like growth factor binding protein-2: NMR analysis and structural characterization of the N-terminal domain.

CA Galea, M Mobli, KA McNeil, TD Mulhern, JC Wallace, GF King, BE Forbes, RS Norton

Journal article  |  2012  |  Biochimie

Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin

Sara L Lawrence, Susanne C Feil, Jessica K Holien, Michael J Kuiper, Larissa Doughty, Olan Dolezal, Terrence D Mulhern, Rodney K Tweten, Michael W Parker

Journal article  |  2012  |  Frontiers in Immunology

ReAsH/FlAsH Labeling and Image Analysis of Tetracysteine Sensor Proteins in Cells

Sevgi Irtegun, Yasmin M Ramdzan, Terrence D Mulhern, Danny M Hatters

Journal article  |  2011  |  Journal of Visualized Experiments

Bacterial expression and purification of active hematopoietic cell kinase

Romana Kristelly, Theresa Wenli Qiu, Natalie J Gunn, Denis B Scanlon, Terrence D Mulhern

Journal article  |  2011  |  Protein Expression and Purification

Purification, crystallization, small-angle X-ray scattering and preliminary X-ray diffraction analysis of the SH2 domain of the Csk-homologous kinase

Natalie J Gunn, Michael A Gorman, Renwick CJ Dobson, Michael W Parker, Terrence D Mulhern

Journal article  |  2011  |  Acta Crystallographica Section F - Structural Biology and Crystallization Communications

Recognition of Mitochondrial Targeting Sequences by the Import Receptors Tom20 and Tom22

Kieran A Rimmer, Jung Hock Foo, Alicia Ng, Emma J Petrie, Patrick J Shilling, Andrew J Perry, Haydyn DT Mertens, Trevor Lithgow, Terrence D Mulhern, Paul R Gooley

Journal article  |  2011  |  Journal of Molecular Biology

Domain Organization of the Monomeric Form of the Tom70 Mitochondrial Import Receptor

Ryan D Mills, Jill Trewhella, Theresa Wenli Qiu, Thomas Welte, Timothy M Ryan, Tracey Hanley, Robert B Knott, Trevor Lithgow, Terrence D Mulhern

Journal article  |  2009  |  Journal of Molecular Biology

Evidence of a Reduced and Modified Mitochondrial Protein Import Apparatus in Microsporidian Mitosomes

Ross F Waller, Carole Jabbour, Nickie C Chan, Nermin Celik, Vladimir A Likic, Terrence D Mulhern, Trevor Lithgow

Journal article  |  2009  |  Eukaryotic Cell

Structure and Function of Human Apolipoprotein

PF James, BW Atcliffe, PR Gooley, T Mulhern, GJ Howlett, RA O'Hair, MAP Perugini

Journal article  |  2009  |  Current Topics in Biochemical Research

Biochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)

Ryan D Mills, Chou Hung Sim, Su San Mok, Terrence D Mulhern, Janetta G Culvenor, Heung-Chin Cheng

Journal article  |  2008  |  Journal of Neurochemistry

Structure, topology and function of the translocase of the outer membrane of mitochondria

Andrew J Perry, Kieran A Rimmer, Haydyn DT Mertens, Ross F Waller, Terrence D Mulhern, Trevor Lithgow, Paul R Gooley

Journal article  |  2008  |  Plant Physiology and Biochemistry

PTEN catalysis of phospholipid dephosphorylation reaction follows a two-step mechanism in which the conserved aspartate-92 does not function as the general acid - Mechanistic analysis of a familial Cowden disease-associated PTEN mutation

Yi Xiao, Joel Yeong Chit Chia, Joanna E Gajewski, Daisy Sio Seng Lio, Terrence D Mulhern, Hong-Jian Zhu, Harshal Nandurkar, Heung-Chin Cheng

Journal article  |  2007  |  Cellular Signaling

A novel binding site for the human insulin-like growth factor-II (IGF-II)/mannose 6-phosphate receptor on IGF-II

Carlie Delaine, Clair L Alvino, Kerrie A McNeil, Terrance D Mulhern, Lisbeth Gauguin, Pierre De Meyts, E Yvonne Jones, James Brown, John C Wallace, Briony E Forbes

Journal article  |  2007  |  Journal of Biological Chemistry

C-terminal Src kinase-homologous kinase (CHK), a unique inhibitor inactivating multiple active conformations of Src family tyrosine kinases

Yuh-Ping Chong, Andrew S Chan, Khai-Chew Chan, Nicholas A Williamson, Edwina C Lerner, Thomas E Smithgall, Jeffrey D Bjorge, Donald J Fujita, Anthony W Purcell, Glen Scholz, Terrence D Mulhern, Heung-Chin Cheng

Journal article  |  2006  |  Journal of Biological Chemistry

The C-terminal TPR domain of Tom70 defines a family of mitochondrial protein import receptors found only in animals and fungi

Nickie C Chan, Vladimir A Likic, Ross F Waller, Terrence D Mulhern, Trevor Lithgow

Journal article  |  2006  |  Journal of Molecular Biology

Engineering of the Escherichia coli Im7 immunity protein as a loop display scaffold

SM Juraja, TD Mulhern, PJ Hudson, MK Hattarki, JA Carmichael, SD Nuttall

Journal article  |  2006  |  Protein Engineering Design & Selection

Improved antigen binding by a CD20-specific single-chain antibody fragment with a mutation in CDRH1

PJ Adamson, DJ Millard, AW Hohmann, C Mavrangelos, PJ Macardle, G Pilkington, TD Mulhern, TF Tedder, H Zola, IC Nicholson

Journal article  |  2006  |  Molecular Immunology

Endogenous and synthetic inhibitors of the Src-family protein tyrosine kinases

YP Chong, KK Ia, TD Mulhern, HC Cheng

Journal article  |  2005  |  Biochimica et Biophysica Acta-Proteins and Proteomics

C-terminal Src kinase (CSK) and CSK-homologous kinase (CHK)-endogenous negative regulators of Src-family protein kinases

YP Chong, TD Mulhern, HC Cheng

Journal article  |  2005  |  Growth Factors

Endogenous and synthetic inhibitors of Src-family protein tyrosine kinases

YP CHONG, K IA, T Mulhern, HC Cheng

Journal article  |  2005  |  Biochimica et Biophysica Acta-Proteins and Proteomics

A biophysical analysis of the tetratricopeptide repeat-rich mitochondrial import receptor, Tom70, reveals an elongated monomer that is inherently flexible, unstable, and unfolds via a multistate pathway

T Beddoe, SR Bushell, MA Perugini, T Lithgow, TD Mulhern, SP Bottomley, J Rossjohn

Journal article  |  2004  |  Journal of Biological Chemistry

Tom22', an 8-kDa trans-site receptor in plants and protozoans, is a conserved feature of the TOM complex that appeared early in the evolution of eukaryotes

D Macasev, J Whelan, E Newbigin, MC Silva-Filho, TD Mulhern, T Lithgow

Journal article  |  2004  |  Molecular Biology and Evolution

A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity

YP Chong, TD Mulhern, HJ Zhu, DJ Fujita, JD Bjorge, JP Tantiongco, N Sotirellis, DSS Lio, G Scholz, HC Cheng

Journal article  |  2004  |  Journal of Biological Chemistry

A novel non-catalytic mechanism employed by the C-terminal Src-homologous kinase to inhibit Src-family kinase activity.

YP CHONG, T Mulhern, H ZHU, D FUJITA, J BJORGE, JP TANTIONGCO, N Sotirellis, SS Lio, G SCHOLZ, HC Cheng

Journal article  |  2004  |  Journal of Biological Chemistry

Letter to the Editor: H-1, C-13 and N-15 chemical shift assignments of the SH2 domain of the Csk homologous kinase

TD Mulhern, C To, HC Cheng

Journal article  |  2002  |  Journal of Biomolecular NMR

The solution structure and intramolecular associations of the Tec kinase Src homology 3 domain

SE Pursglove, TD Mulhern, JP Mackay, MG Hinds, GW Booker

Journal article  |  2002  |  Journal of Biological Chemistry

1H, 13C and 15N chemical shift assignments of the SH2 domain of the Csk homologous kinase

T MULHERN, C TO, HC CHENG

Journal article  |  2002  |  Journal of Biomolecular NMR

The C-terminal domain of biotin protein ligase from E-coli is required for catalytic activity

A Chapman-Smith, TD Mulhern, F Whelan, JE Cronan, JC Wallace

Journal article  |  2001  |  Protein Science

ATM, a central controller of cellular responses to DNA damage

KK Khanna, MF Lavin, SP Jackson, TD Mulhern

Journal article  |  2001  |  Cell Death and Differentiation

ATM, a central controller of cellular responses to DNA damage

KK Khanna, MF Lavin, SP Jackson, TD Mulhern

Journal article  |  2001  |  Cell Death & Differentiation

Sedimentation analysis of novel DNA structures formed by homo-oligonucleotides

DM Hatters, L Wilson, BW Atcliffe, TD Mulhern, N Guzzo-Pernell, GJ Howlett

Journal article  |  2001  |  Biophysical Journal

The role of the Src homology 3-Src homology 2 interface in the regulation of Src kinases

ST Arold, TS Ulmer, TD Mulhern, JM Werner, JE Ladbury, ID Campbell, MEM Noble

Journal article  |  2001  |  Journal of Biological Chemistry

Mutational analysis of protein substrate presentation in the post-translational attachment of biotin to biotin domains

SW Polyak, A Chapman-Smith, TD Mulhern, JE Cronan, JC Wallace

Journal article  |  2001  |  Journal of Biological Chemistry

Erratum: Maculatin 1.1, an anti-microbial peptide from the australian tree frog, Litoria genimaculata. Solution structure and biological activity (European Journal of Biochemistry (2000) 267 (1894-1908))

BCS Chia, JA Carver, TD Mulhern, JH Bowie

Journal article  |  2000  |  European Journal of Biochemistry

The solution structure of the cytokine-binding domain of the common beta-chain of the receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3 and interleukin-5

TD Mulhern, AF Lopez, RJ D'Andrea, C Gaunt, L Vandeleur, MA Vadas, GW Booker, CJ Bagley

Journal article  |  2000  |  Journal of Molecular Biology

Maculatin 1.1, an anti-microbial peptide from the Australian tree frog, Litoria genimaculata - Solution structure and biological activity

BCS Chia, JA Carver, TD Mulhern, JH Bowie

Journal article  |  2000  |  European Journal of Biochemistry

Probing the nature of interactions in SH2 binding interfaces - Evidence from electrospray ionization mass spectrometry

EW Chung, DA Henriques, D Renzoni, CJ Morton, TD Mulhern, MC Pitkeathly, JE Ladbury, CV Robinson

Journal article  |  1999  |  Protein Science

The solution structure of uperin 3.6, an antibiotic peptide from the granular dorsal glands of the Australian toadlet, Uperoleia mjobergii

BCS Chia, JA Carver, TD Mulhern, JH Bowie

Journal article  |  1999  |  Journal of Peptide Research

H-1 and N-15 chemical shift assignments for domain 4 of the common beta-chain of the IL-3, IL-5 and GM-CSF receptors

TD Mulhern, CJ Bagley, C Gaunt, AF Lopez, MA Vadas, RJ D'Andrea, GW Booker

Journal article  |  1999  |  Journal of Biomolecular NMR

A third fibronectin type-III domain in the insulin-family receptors

TD Mulhern, GW Booker, L Cosgrove

Journal article  |  1998  |  Trends in Biochemical Sciences

Assignment of H-1 and N-15 resonances of murine Tec SH3 domain

SE Pursglove, TD Mulhern, MG Hinds, RS Norton, GW Booker

Journal article  |  1998  |  Journal of Biomolecular NMR

The SH2 domain from the tyrosine kinase Fyn in complex with a phosphotyrosyl peptide reveals insights into domain stability and binding specificity

TD Mulhern, GL Shaw, CJ Morton, AJ Day, ID Campbell

Journal article  |  1997  |  Structure

Bound tris confounds the identification of binding site residues in a paraquat single chain antibody

MR Bowles, TD Mulhern, RB Gordon, HR Inglis, IA Sharpe, JL Cogill, SM Pond

Journal article  |  1997  |  Journal of Biochemistry

SOLUTION STRUCTURE OF A POLYPEPTIDE CONTAINING 4 HEPTAD REPEAT UNITS FROM A MEROZOITE SURFACE-ANTIGEN OF PLASMODIUM-FALCIPARUM

TD MULHERN, GJ HOWLETT, GE REID, RJ SIMPSON, DJ MCCOLL, RF ANDERS, RS NORTON

Journal article  |  1995  |  Biochemistry